메뉴 건너뛰기




Volumn 17, Issue 1, 1996, Pages 47-54

Differential modulation of prohormone convertase mRNA by second messenger activators in two cholecystokinin-producing cell lines

Author keywords

cAMP; Cell lines; Gene regulation; Peptide regulation; Peptide synthesis; PKC; Prohormone convertase; Second messengers

Indexed keywords

CYCLIC AMP; ENDOGENOUS COMPOUND; FURIN; HORMONE PRECURSOR; ISOBUTYLMETHYLXANTHINE; MESSENGER RNA; PHORBOL ESTER; PHOSPHODIESTERASE INHIBITOR; PROTEIN KINASE C;

EID: 0030067873     PISSN: 01969781     EISSN: None     Source Type: Journal    
DOI: 10.1016/0196-9781(95)02044-6     Document Type: Article
Times cited : (14)

References (30)
  • 1
    • 0028292383 scopus 로고
    • Expression of the dibasic processing enzyme furin is directed by multiple promoters
    • Ayoubi, T. A.; Creemers, J. W. M.; Roebroek, A. J. M.; Van de Ven, W. J. M. Expression of the dibasic processing enzyme furin is directed by multiple promoters. J. Biol. Chem. 269:9298-9303; 1994.
    • (1994) J. Biol. Chem. , vol.269 , pp. 9298-9303
    • Ayoubi, T.A.1    Creemers, J.W.M.2    Roebroek, A.J.M.3    Van De Ven, W.J.M.4
  • 2
    • 0025733702 scopus 로고
    • Mammalian subtilisins: The long-sought dibasic processing endoproteases
    • Barr, P. J. Mammalian subtilisins: The long-sought dibasic processing endoproteases. Cell 66:1-3; 1991.
    • (1991) Cell , vol.66 , pp. 1-3
    • Barr, P.J.1
  • 3
    • 0025763617 scopus 로고
    • cDNA and gene structure for a human subtilisin-like protease with cleavage specificity for paired basic amino acid residues
    • Barr, P. J.; Mason, O. B.; Landsberg, K. E.; Wong, P. A.; Kiefer, M. C.; Brake, A. J. cDNA and gene structure for a human subtilisin-like protease with cleavage specificity for paired basic amino acid residues. DNA Cell Biol. 10:319-328; 1991.
    • (1991) DNA Cell Biol. , vol.10 , pp. 319-328
    • Barr, P.J.1    Mason, O.B.2    Landsberg, K.E.3    Wong, P.A.4    Kiefer, M.C.5    Brake, A.J.6
  • 4
    • 0026771073 scopus 로고
    • Regulation of cholecystokinin secretion from a rat medullary thyroid carcinoma cell line: Role of calcium, cyclic nucleotides, glucocorticoids, neurotensin, and calcitonin gene-related peptide
    • Beinfeld, M. C.; Haun, R. S.; Allard, L. R.; Dixon, J. E. Regulation of cholecystokinin secretion from a rat medullary thyroid carcinoma cell line: Role of calcium, cyclic nucleotides, glucocorticoids, neurotensin, and calcitonin gene-related peptide. Peptides 13:545-550; 1992.
    • (1992) Peptides , vol.13 , pp. 545-550
    • Beinfeld, M.C.1    Haun, R.S.2    Allard, L.R.3    Dixon, J.E.4
  • 5
    • 0019497036 scopus 로고
    • The distribution of cholecystokinin in the central nervous system of the rat as determined by radioimmunoassay
    • Beinfeld, M. C.; Meyer, D. K.; Eskay, R. L.; Jensen, R. T.; Brownstein, M. J. The distribution of cholecystokinin in the central nervous system of the rat as determined by radioimmunoassay. Brain Res. 212:51-57; 1981.
    • (1981) Brain Res. , vol.212 , pp. 51-57
    • Beinfeld, M.C.1    Meyer, D.K.2    Eskay, R.L.3    Jensen, R.T.4    Brownstein, M.J.5
  • 6
    • 0027765503 scopus 로고
    • Differential processing of proenkephalin by prohormone convertases 1(3) and 2 and furin
    • Breslin, M. B.; Lindberg, I.; Benjannet, S.; Mathis, J. P.; Lazure, C.; Seidah, N. Differential processing of proenkephalin by prohormone convertases 1(3) and 2 and furin. J. Biol. Chem. 268:27084-27093; 1993.
    • (1993) J. Biol. Chem. , vol.268 , pp. 27084-27093
    • Breslin, M.B.1    Lindberg, I.2    Benjannet, S.3    Mathis, J.P.4    Lazure, C.5    Seidah, N.6
  • 7
    • 0026351028 scopus 로고
    • Neuroanatomical and functional studies of peptide precursor-processing enzymes
    • Cullinan, W. E.; Day, N. C.; Schäfer, M. K.-H.; et al. Neuroanatomical and functional studies of peptide precursor-processing enzymes. Enzyme 45:285-300; 1991.
    • (1991) Enzyme , vol.45 , pp. 285-300
    • Cullinan, W.E.1    Day, N.C.2    Schäfer, M.K.-H.3
  • 8
    • 0026609102 scopus 로고
    • Distribution and regulation of the prohormone convertase PC1 and PC2 in the rat pituitary
    • Day, R. M.; Schäfer, M. K.-H.; Watson, S. J.; Chrétien, M.; Seidah, N. G. Distribution and regulation of the prohormone convertase PC1 and PC2 in the rat pituitary. Mol. Endocrinol. 6:485-497; 1992.
    • (1992) Mol. Endocrinol. , vol.6 , pp. 485-497
    • Day, R.M.1    Schäfer, M.K.-H.2    Watson, S.J.3    Chrétien, M.4    Seidah, N.G.5
  • 9
    • 0028078905 scopus 로고
    • Processing of prodynorphin by the prohormone convertase PC1 results in high molecular weight intermediate forms
    • Dupuy, A.; Lindberg, I.; Zhou, Y.; et al. Processing of prodynorphin by the prohormone convertase PC1 results in high molecular weight intermediate forms. FEBS Lett. 337:60-65; 1994.
    • (1994) FEBS Lett. , vol.337 , pp. 60-65
    • Dupuy, A.1    Lindberg, I.2    Zhou, Y.3
  • 10
    • 0024307590 scopus 로고
    • Establishment of a cholecystokinin-producing rat medullary thyroid carcinoma cell line
    • Haun, R. S.; Beinfeld, M. C.; Roos, B. A.; Dixon, J. E. Establishment of a cholecystokinin-producing rat medullary thyroid carcinoma cell line. Endocrinology 125:850-856; 1989.
    • (1989) Endocrinology , vol.125 , pp. 850-856
    • Haun, R.S.1    Beinfeld, M.C.2    Roos, B.A.3    Dixon, J.E.4
  • 11
    • 0025916877 scopus 로고
    • Arg-X-Lys/Arg-Arg motif as a signal for precursor cleavage catalyzed by furin within the constitutive secretory pathway
    • Hosaka, M.; Nagahama, M.; Kim, W-S.; et al. Arg-X-Lys/Arg-Arg motif as a signal for precursor cleavage catalyzed by furin within the constitutive secretory pathway. J. Biol. Chem. 266:12127-12130; 1991.
    • (1991) J. Biol. Chem. , vol.266 , pp. 12127-12130
    • Hosaka, M.1    Nagahama, M.2    Kim, W.-S.3
  • 12
    • 0025646802 scopus 로고
    • Subtilisin-like proteinases involved in the activation of proproteins of the eukaryotic secretory pathway
    • Hutton, J. C. Subtilisin-like proteinases involved in the activation of proproteins of the eukaryotic secretory pathway. Curr. Opin. Biol. 2:1131-1142; 1990.
    • (1990) Curr. Opin. Biol. , vol.2 , pp. 1131-1142
    • Hutton, J.C.1
  • 13
    • 0026348132 scopus 로고
    • Identification of a second human subtilisin-like protease gene in the fes/fps region of chromosome 15
    • Kiefer, M. C.; Tucker, J. E.; Joh, R.; Landsberg, K. E.; Saltman, D.; Barr, P. J. Identification of a second human subtilisin-like protease gene in the fes/fps region of chromosome 15. DNA Cell Biol. 10:757-769; 1991.
    • (1991) DNA Cell Biol. , vol.10 , pp. 757-769
    • Kiefer, M.C.1    Tucker, J.E.2    Joh, R.3    Landsberg, K.E.4    Saltman, D.5    Barr, P.J.6
  • 14
    • 0027234185 scopus 로고
    • Processing, release and metabolism of cholecystokinin in SK-N-MCIXC cells
    • Konings, P. N. M.; Mania-Farnell, B.; Beinfeld, M. C.; et al. Processing, release and metabolism of cholecystokinin in SK-N-MCIXC cells. Neuropeptides 25:9-30; 1993.
    • (1993) Neuropeptides , vol.25 , pp. 9-30
    • Konings, P.N.M.1    Mania-Farnell, B.2    Beinfeld, M.C.3
  • 15
    • 0027274628 scopus 로고
    • cDNA structure of the mouse and rat subtilisin/kexin-like PC5: A candidate proprotein convertase expressed in endocrine and nonendocrine cells
    • Lusson, J.; Vieau, D.; Hamelin, J.; Day, R.; Chrétien, M.; Seidah, N. cDNA structure of the mouse and rat subtilisin/kexin-like PC5: A candidate proprotein convertase expressed in endocrine and nonendocrine cells. Proc. Natl. Acad. Sci. USA 90:691-6695; 1993.
    • (1993) Proc. Natl. Acad. Sci. USA , vol.90 , pp. 691-6695
    • Lusson, J.1    Vieau, D.2    Hamelin, J.3    Day, R.4    Chrétien, M.5    Seidah, N.6
  • 16
    • 0027332928 scopus 로고
    • Regulation of CCK mRNA in the human neuroepithelioma cell line SK-N-MCIXC in response to second messenger activators
    • Mania-Farnell, B. L.; Merrill, B. J.; Konings, P. N. M.; Davis, T. P. Regulation of CCK mRNA in the human neuroepithelioma cell line SK-N-MCIXC in response to second messenger activators. FEBS Lett. 335:65-68; 1993.
    • (1993) FEBS Lett. , vol.335 , pp. 65-68
    • Mania-Farnell, B.L.1    Merrill, B.J.2    Konings, P.N.M.3    Davis, T.P.4
  • 17
    • 0026775916 scopus 로고
    • Human furin is a calcium-dependent serine endoprotease that recognizes the sequence Arg-X-X-Arg and efficiently cleaves anthrax toxin protective antigen
    • Molloy, S. S.; Bresnahan, P. A.; Leppla, S. H.; Klimpel, K. R.; Thomas, G. Human furin is a calcium-dependent serine endoprotease that recognizes the sequence Arg-X-X-Arg and efficiently cleaves anthrax toxin protective antigen. J. Biol. Chem. 267:16396-16402; 1992.
    • (1992) J. Biol. Chem. , vol.267 , pp. 16396-16402
    • Molloy, S.S.1    Bresnahan, P.A.2    Leppla, S.H.3    Klimpel, K.R.4    Thomas, G.5
  • 18
    • 0027419621 scopus 로고
    • Identification and functional expression of a new member of the mammalian Kex2-like processing endoprotease family: Its striking similarity to PACE4
    • Nakagawa, T.; Hosaka, M.; Torii, S.; Watanabe, T.; Muakami, K.; Nakayama, K. Identification and functional expression of a new member of the mammalian Kex2-like Processing endoprotease family: Its striking similarity to PACE4. J. Biochem. 113:132-135; 1993.
    • (1993) J. Biochem. , vol.113 , pp. 132-135
    • Nakagawa, T.1    Hosaka, M.2    Torii, S.3    Watanabe, T.4    Muakami, K.5    Nakayama, K.6
  • 19
    • 0026660354 scopus 로고
    • Identification of the fourth member of the mammalian endoprotease family homologous to the yeast Kex2 protease: Its testis-specific expression
    • Nakayama, K.; Kim, W.-S.; Torij, S.; et al. Identification of the fourth member of the mammalian endoprotease family homologous to the yeast Kex2 protease: Its testis-specific expression. J. Biol. Chem. 267:5897-5900; 1992.
    • (1992) J. Biol. Chem. , vol.267 , pp. 5897-5900
    • Nakayama, K.1    Kim, W.-S.2    Torij, S.3
  • 20
    • 0022779175 scopus 로고
    • Evolutionary conserved close linkage of c-fes/fps proto-oncogene and genetic sequences encoding a receptor-like protein
    • Roebroek, A. J. M.; Schalken, J. A.; Leunissen, J. A. M.; Onnekink, C.; Bloemers, P. J.; Van de Ven, W. J. M. Evolutionary conserved close linkage of c-fes/fps proto-oncogene and genetic sequences encoding a receptor-like protein. EMBO J. 5:2197-2202; 1986.
    • (1986) EMBO J. , vol.5 , pp. 2197-2202
    • Roebroek, A.J.M.1    Schalken, J.A.2    Leunissen, J.A.M.3    Onnekink, C.4    Bloemers, P.J.5    Van De Ven, W.J.M.6
  • 21
    • 0027404880 scopus 로고
    • Gene expression of prohormone and proprotein convertases in the rat CNS: A comparative in situ hybridization analysis
    • Schäfer, M. K.-H.; Day, R.; Cullinan, W. E.; Chrétien, M.; Seidah, N. G.; Watson, S. J. Gene expression of prohormone and proprotein convertases in the rat CNS: A comparative in situ hybridization analysis. J. Neurosci. 13:1258-1279; 1993.
    • (1993) J. Neurosci. , vol.13 , pp. 1258-1279
    • Schäfer, M.K.-H.1    Day, R.2    Cullinan, W.E.3    Chrétien, M.4    Seidah, N.G.5    Watson, S.J.6
  • 22
    • 0025622849 scopus 로고
    • cDNA sequence of two distinct pituitary proteins homologous to kex2 and furin gene products: Tissue-specific mRNAs encoding candidates for pro-hormone processing proteinases
    • Seidah, N. G.; Gaspar, L.; Mion, P.; Marcinkiewicz, M.; Mbikay, M.; Chrétien, M. cDNA sequence of two distinct pituitary proteins homologous to kex2 and furin gene products: Tissue-specific mRNAs encoding candidates for pro-hormone processing proteinases. DNA Cell Biol. 9:415-424; 1990.
    • (1990) DNA Cell Biol. , vol.9 , pp. 415-424
    • Seidah, N.G.1    Gaspar, L.2    Mion, P.3    Marcinkiewicz, M.4    Mbikay, M.5    Chrétien, M.6
  • 23
    • 0026725984 scopus 로고
    • The cDNA sequence of the human pro-hormone and pro-protein convertase PC1
    • Seidah, N. G.; Hamelin, J.; Gaspar, A. M.; Day, R.; Chrétien, M. The cDNA sequence of the human pro-hormone and pro-protein convertase PC1. DNA Cell Biol. 11:283-289; 1992.
    • (1992) DNA Cell Biol. , vol.11 , pp. 283-289
    • Seidah, N.G.1    Hamelin, J.2    Gaspar, A.M.3    Day, R.4    Chrétien, M.5
  • 24
    • 0025803098 scopus 로고
    • Cloning and primary sequence of a mouse candidate prohormone convertase PC1 homologous to PC2, furin, and kex2: Distinct chromosomal localization and messenger RNA distribution in brain and pituitary compared to PC2
    • Seidah, N. G.; Marcinkiewicz, M.; Benjannet, S.; et al. Cloning and primary sequence of a mouse candidate prohormone convertase PC1 homologous to PC2, furin, and kex2: Distinct chromosomal localization and messenger RNA distribution in brain and pituitary compared to PC2. Mol. Endocrinol. 5:111-122; 1993.
    • (1993) Mol. Endocrinol. , vol.5 , pp. 111-122
    • Seidah, N.G.1    Marcinkiewicz, M.2    Benjannet, S.3
  • 25
    • 0026088633 scopus 로고
    • Identification of a cDNA encoding a second putative prohormone convertase related to PC2 in AtT20 cells and islets of Langerhans
    • Smeekens, S. P.; Avruch, A. S.; LaMendola, J.; Chan, S. J.; Steiner, D. F. Identification of a cDNA encoding a second putative prohormone convertase related to PC2 in AtT20 cells and islets of Langerhans. Proc. Natl. Acad. Sci. USA 88:340-344; 1991.
    • (1991) Proc. Natl. Acad. Sci. USA , vol.88 , pp. 340-344
    • Smeekens, S.P.1    Avruch, A.S.2    LaMendola, J.3    Chan, S.J.4    Steiner, D.F.5
  • 26
    • 0025214491 scopus 로고
    • Identification of a human insulinoma cDNA encoding a novel mammalian protein structurally related to the yeast dibasic processing protease kex2
    • Smeekens, S. P.; Steiner, D. F. Identification of a human insulinoma cDNA encoding a novel mammalian protein structurally related to the yeast dibasic processing protease kex2. J. Biol. Chem. 265:2997-3000; 1990.
    • (1990) J. Biol. Chem. , vol.265 , pp. 2997-3000
    • Smeekens, S.P.1    Steiner, D.F.2
  • 27
    • 0342798531 scopus 로고
    • Prohormone convertases revealed at last
    • Steiner, D. F. Prohormone convertases revealed at last. Curr. Biol. 1:375-377; 1991.
    • (1991) Curr. Biol. , vol.1 , pp. 375-377
    • Steiner, D.F.1
  • 28
    • 0027186357 scopus 로고
    • Transactivation by NF-IL6/LAP is enhanced by phosphorylation of its activation domain
    • Trautwein, C.; Caelles, C.; van der Geer, P.; Hunter, T.; Karin, M.; Chojkier, M. Transactivation by NF-IL6/LAP is enhanced by phosphorylation of its activation domain. Nature 364:544-547; 1993.
    • (1993) Nature , vol.364 , pp. 544-547
    • Trautwein, C.1    Caelles, C.2    Van Der Geer, P.3    Hunter, T.4    Karin, M.5    Chojkier, M.6
  • 29
    • 0025301506 scopus 로고
    • The cholecystokinin gene is abundantly co-expressed with gastrin-releasing peptide, enkephalin and neuropeptide Y genes in a clonal human neuroepithelioma cell line
    • Verbeeck, M. A. E.; Burbach, J. P. H. The cholecystokinin gene is abundantly co-expressed with gastrin-releasing peptide, enkephalin and neuropeptide Y genes in a clonal human neuroepithelioma cell line. FEBS Lett. 268:88-90; 1990.
    • (1990) FEBS Lett. , vol.268 , pp. 88-90
    • Verbeeck, M.A.E.1    Burbach, J.P.H.2
  • 30
    • 0025606360 scopus 로고
    • Expression of a human proprotein processing enzyme: Correct cleavage of von willebrand factor precursor at a paired basic amino site
    • Wise, R. J.; Barr, P. J.; Wong, P. A.; Kiefer, M. C.; Brake, A. J.; Kaufman, R. J. Expression of a human proprotein processing enzyme: Correct cleavage of von Willebrand factor precursor at a paired basic amino site. Proc. Natl. Acad. Sci. USA 87:9378-9382; 1990.
    • (1990) Proc. Natl. Acad. Sci. USA , vol.87 , pp. 9378-9382
    • Wise, R.J.1    Barr, P.J.2    Wong, P.A.3    Kiefer, M.C.4    Brake, A.J.5    Kaufman, R.J.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.