Randomized, double blind comparison of brand and generic antibiotic suspensions: II. A study of taste and compliance in children

Pediatric Infectious Disease Journal

Volumn 15, Issue 1, 1996, Pages 18-22

  El Chaar, Gladys M ^a,b   Mardy, Gisele ^b   Wehlou, Kicki ^b   Rubin, Lorry G ^b  

^a ST JOHN'S UNIVERSITY   (United States)

^b SCHNEIDER CHILDREN'S HOSPITAL   (United States)

Author keywords

antibiotic; brand; children; compliance; generic; Palatability

Indexed keywords

ANTIBIOTIC AGENT; CEFALEXIN; COTRIMOXAZOLE; ERYTHROMYCIN ETHYLSUCCINATE; GENERIC DRUG; PEDIAZOLE; SULFAFURAZOLE;

ADOLESCENT; ANTIBIOTIC THERAPY; ARTICLE; BACTERIAL INFECTION; CHILD; CHILDHOOD DISEASE; CLINICAL ARTICLE; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; CROSSOVER PROCEDURE; DOUBLE BLIND PROCEDURE; DRUG COST; DRUG FORMULATION; FEMALE; HUMAN; MALE; ORAL DRUG ADMINISTRATION; PALATABILITY; PATIENT COMPLIANCE; PHARYNGITIS; PRIORITY JOURNAL; RANDOMIZED CONTROLLED TRIAL; SCARLET FEVER; STREPTOCOCCUS INFECTION;

ADOLESCENT; ANTI-BACTERIAL AGENTS; CEPHALEXIN; CHILD; CHILD, PRESCHOOL; DOUBLE-BLIND METHOD; DRUG COMPOUNDING; DRUG THERAPY, COMBINATION; DRUGS, GENERIC; ERYTHROMYCIN; FEMALE; HUMANS; MALE; PATIENT COMPLIANCE; PATIENT SATISFACTION; SULFISOXAZOLE; TASTE; TRIMETHOPRIM-SULFAMETHOXAZOLE COMBINATION;

EID: 0030067844     PISSN: 08913668     EISSN: None     Source Type: Journal    
DOI: 10.1097/00006454-199601000-00004     Document Type: Article

References (10)

1. Demers DM, Chan DS, Bass JW. Antimicrobial drug suspensions: a blinded comparison of taste of twelve common pediatric drugs including cefixime, cefpodoxime, cefprozil and loracarbef. Pediatr Infect Dis J 1994;13:87-9.
2. Greenberg RN. Overview of patient compliance with medication dosing: a literature review. Clin Ther 1984;6:592-9.
3. Dagan R, Shvartzman P, Liss Z. Variation in acceptance of common oral antibiotic suspensions. Pediatr Infect Dis J 1994;13:686-90.
4. Prenson SA. The health needs of infants and children under 12. In: Better health for our children: a national strategy. Publication PHS 79-55071. vol. 4. United States Department of Health and Human Services. Washington, DC: United States Government Printing Office, 1981:243-83.
5. Nightingale SL, Morrison JC. Generic drugs and the prescribing physician. JAMA 1987;258:1200-4.
6. Sjovall J, Fogh A, Huifeldt B, Karlsson G, Nylen O. Methods for evaluating the taste of paediatric formulations in children: a comparison between the facial hedonic method and the patient's own spontaneous verbal judgment. Eur J Pediatr 1984;141:243-7.
7. Bagger-Sjoback D, Bondesson G. Taste evaluation and compliance of two paediatric formulations of phenoxymethylpenicillin in children. Scand J Prim Health Care 1989;7:87-92.
8. Uhari M, Eskelinen L, Jokisalo J. Acceptance of antibiotic mixtures by infants and children. Eur J Clin Pharmacol 1986;30:503-4.
9. Jahnsen T, Thorn P. An acceptability study of two pivampicillin mixtures in children in general practice. Scand J Prim Health Care 1987;5:241-3.
10. Samulak KM, El-Chaar GM, Rubin LG. Randomized, double blind comparison of brand and generic antibiotic suspensions: I. A study of taste in adults. Pediatr Infect Dis J 1996;15:14-7.