Sparoxomycins A1 and A2, new inducers of the flat reversion of NRK cells transformed by temperature sensitive rous sarcoma virus II. Isolation, physico-chemical properties and structure elucidation

Journal of Antibiotics

Volumn 49, Issue 1, 1996, Pages 65-70

  Ubukata, Makoto ^a,b   Morita, Tetsu Ichiro ^a,c   Uramoto, Masakazu ^c   Osada, Hiroyuki ^a  

^a INST OF PHYS AND CHEMICAL RESEARCH   (Japan)

^b TOYAMA PREFECTURAL UNIVERSITY   (Japan)

^c TAMAGAWA UNIVERSITY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

SPAROXOMYCIN A1; SPAROXOMYCIN A2; UNCLASSIFIED DRUG;

ARTICLE; CARBON NUCLEAR MAGNETIC RESONANCE; CELL ACTIVITY; CELL TRANSFORMATION; CHROMATOGRAPHY; COLUMN CHROMATOGRAPHY; DRUG ISOLATION; DRUG STRUCTURE; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; PARTITION CHROMATOGRAPHY; PHYSICAL CHEMISTRY; PRIORITY JOURNAL; PROTON NUCLEAR MAGNETIC RESONANCE; STEREOCHEMISTRY; STREPTOMYCES;

ANTIBIOTICS, ANTINEOPLASTIC; AVIAN SARCOMA VIRUSES; CELL TRANSFORMATION, NEOPLASTIC; MOLECULAR CONFORMATION; PYRIMIDINONES; TEMPERATURE;

EID: 0030067734     PISSN: 00218820     EISSN: None     Source Type: Journal    
DOI: 10.7164/antibiotics.49.65     Document Type: Article

References (8)

1. UBUKATA, M.; T.-I. MORITA, H. KAKEYA, K. KOBINATA, T. KUDO & H. OSADA: Sparoxomycins A1 and A2, new inducers of the flat reversion of NRK cells transformed by temperature sensitive Rous sarcoma virus. I. Taxonomy of the producing organism, fermentation and biological activity. J. Antibiotics, in preparation
2. HWANG, D.-R.; P. HELQUIST & M. S. SHEKHANI: Total synthesis of (+)-sparsomycin. Approaches using cysteine and serine inversion. J. Org. Chem. 50: 1264-1271, 1985
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6. MISLOW, K.; M. M. GREEN, P. LAUR, J. T. MELILLO, T. SIMMONS, A. L. TERNAY Jr: Absolute configuration and optical rotatory power of sulfoxides and sulfinate esters. J. Am. Chem. Soc. 87: 1958-1976, 1965
7. AXELROD, M.; P. BICKART, M. L. GOLDSTEIN, M. M. GREEN, A. KJAER & K. MISLOW: Absolute configuration and optical rotatory dispersion of methyl alkyl sulfoxides. Tetrahedron Lett. 3249-3252, 1968
8. ARGOUDELIS, A. D. & R. R. HERR: Sparsomycin, a new antitumor antibiotic II. Isolation and characterization. Antimicrob. Agents Chemother. 780-786, 1962