메뉴 건너뛰기




Volumn 70, Issue 3, 1996, Pages 1535-1541

Downstream regulatory elements increase acute and latent herpes simplex virus type 2 latency-associated transcript expression but do not influence recurrence phenotype or establishment of latency

Author keywords

[No Author keywords available]

Indexed keywords

ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; CELL CULTURE; GENE DELETION; GENETIC TRANSCRIPTION; GUINEA PIG; HERPES SIMPLEX VIRUS 2; HUMAN; HUMAN CELL; INTRON; NONHUMAN; PRIORITY JOURNAL; PROMOTER REGION; REGULATOR GENE; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; VIRUS EXPRESSION; VIRUS INFECTION; VIRUS LATENCY; VIRUS MUTANT; VIRUS REACTIVATION;

EID: 0030067688     PISSN: 0022538X     EISSN: None     Source Type: Journal    
DOI: 10.1128/jvi.70.3.1535-1541.1996     Document Type: Article
Times cited : (21)

References (43)
  • 1
    • 0025336767 scopus 로고
    • Regulation and cell-type-specific activity of a promoter located upstream of the latency-associated transcript of herpes simplex virus type 1
    • Batchelor, A. H., and P. O'Hare. 1990. Regulation and cell-type-specific activity of a promoter located upstream of the latency-associated transcript of herpes simplex virus type 1. J. Virol. 64:3269-3279.
    • (1990) J. Virol. , vol.64 , pp. 3269-3279
    • Batchelor, A.H.1    O'Hare, P.2
  • 2
    • 0028010088 scopus 로고
    • Molecular analysis of herpes simplex virus type 1 during epinephrine-induced reactivation of latently infected rabbits in vivo
    • Bloom, D. C., G. B. Devi-Rao, J. M. Hill, J. G. Stevens, and E. K. Wagner. 1994 Molecular analysis of herpes simplex virus type 1 during epinephrine-induced reactivation of latently infected rabbits in vivo. J. Virol. 68:1283-1292
    • (1994) J. Virol. , vol.68 , pp. 1283-1292
    • Bloom, D.C.1    Devi-Rao, G.B.2    Hill, J.M.3    Stevens, J.G.4    Wagner, E.K.5
  • 3
    • 0027934653 scopus 로고
    • Quantity of latency associated transcript produced by herpes simplex virus is not predictive of the frequency of experimental recurrent genital herpes
    • Bourne, N., L. R. Stanberry, B. Connelly, J. F. Kurawadwala, S. E. Straus, and P. R. Krause. 1994. Quantity of latency associated transcript produced by herpes simplex virus is not predictive of the frequency of experimental recurrent genital herpes. J. Infect. Dis. 169:1084-1087
    • (1994) J. Infect. Dis. , vol.169 , pp. 1084-1087
    • Bourne, N.1    Stanberry, L.R.2    Connelly, B.3    Kurawadwala, J.F.4    Straus, S.E.5    Krause, P.R.6
  • 4
    • 0022646583 scopus 로고
    • Injections with herpes simplex viruses N
    • Corey, L., and P. G. Spear. 1986. Injections with herpes simplex viruses N. Engl J Med. 314:686-691.
    • (1986) Engl J Med. , vol.314 , pp. 686-691
    • Corey, L.1    Spear, P.G.2
  • 5
    • 0025967411 scopus 로고
    • Characterization of herpes simplex virus type 2 latency associated transcription in human sacral ganglia and in cell culture
    • Croen, K. D., L. Dragovic, J. M. Ostrove, and S. E. Straus. 1991. Characterization of herpes simplex virus type 2 latency associated transcription in human sacral ganglia and in cell culture. J. Infect. Dis 163:23-28.
    • (1991) J. Infect. Dis , vol.163 , pp. 23-28
    • Croen, K.D.1    Dragovic, L.2    Ostrove, J.M.3    Straus, S.E.4
  • 8
    • 0009602729 scopus 로고
    • RNA from an immediate early region of the HSV-1 genome is present in the trigeminal ganglia of latently infected mice
    • Deatly, A. M., J. G. Spivack, E. Lavi, and N. W. Fraser. 1987 RNA from an immediate early region of the HSV-1 genome is present in the trigeminal ganglia of latently infected mice. Proc. Natl. Acad. Sci. USA 84:3204-3208.
    • (1987) Proc. Natl. Acad. Sci. USA , vol.84 , pp. 3204-3208
    • Deatly, A.M.1    Spivack, J.G.2    Lavi, E.3    Fraser, N.W.4
  • 9
    • 0028903361 scopus 로고
    • In vivo deletion analysis of the herpes simplex virus type 1 latency-associated transcript promoter
    • Dobson, A. T., T. P. Margolis, W. A. Gomes, and L. T. Feldman. 1995. In vivo deletion analysis of the herpes simplex virus type 1 latency-associated transcript promoter. J. Virol 69:2264-2270.
    • (1995) J. Virol , vol.69 , pp. 2264-2270
    • Dobson, A.T.1    Margolis, T.P.2    Gomes, W.A.3    Feldman, L.T.4
  • 10
    • 0024311526 scopus 로고
    • Identification of the latency-associated transcript promoter by expression of rabbit beta-globin mRNA in mouse sensory ganglia latently infected with a recombinant herpes simplex virus
    • Dobson, A. T., F. Sederati, G. Devi-Rao, M. W. Flanagan, M. J. Farrell, J. G. Stevens, E. K. Wagner, and L. T. Feldman. 1989. Identification of the latency-associated transcript promoter by expression of rabbit beta-globin mRNA in mouse sensory ganglia latently infected with a recombinant herpes simplex virus. J. Virol. 63:3844-3851.
    • (1989) J. Virol. , vol.63 , pp. 3844-3851
    • Dobson, A.T.1    Sederati, F.2    Devi-Rao, G.3    Flanagan, M.W.4    Farrell, M.J.5    Stevens, J.G.6    Wagner, E.K.7    Feldman, L.T.8
  • 11
    • 0027181073 scopus 로고
    • Reactivation in vivo and in vitro of herpes simplex virus from mouse dorsal root ganglia which contain different levels of latency-associated transcripts
    • Ecob-Prince, M. S., F. J. Rixon, C. M. Preston, K. Hassan, and P. G. Kennedy. 1993. Reactivation in vivo and in vitro of herpes simplex virus from mouse dorsal root ganglia which contain different levels of latency-associated transcripts. J. Gen. Virol. 74:995-1002.
    • (1993) J. Gen. Virol. , vol.74 , pp. 995-1002
    • Ecob-Prince, M.S.1    Rixon, F.J.2    Preston, C.M.3    Hassan, K.4    Kennedy, P.G.5
  • 12
    • 0026025927 scopus 로고
    • Herpes simplex virus latency-associated transcript is a stable intron
    • Farrell, M. J., A. T. Dobson, and L. T. Feldman. 1991. Herpes simplex virus latency-associated transcript is a stable intron. Proc. Natl. Acad. Sci. USA 88:790-794.
    • (1991) Proc. Natl. Acad. Sci. USA , vol.88 , pp. 790-794
    • Farrell, M.J.1    Dobson, A.T.2    Feldman, L.T.3
  • 14
    • 0025166428 scopus 로고
    • Herpes simplex virus latent phase facilitates in vivo reactivation
    • Hill, J. M., F. Sedarati, R. T. Javier, E. K. Wagner, and J. G. Stevens. 1990. Herpes simplex virus latent phase facilitates in vivo reactivation. Virology 174:117-125.
    • (1990) Virology , vol.174 , pp. 117-125
    • Hill, J.M.1    Sedarati, F.2    Javier, R.T.3    Wagner, E.K.4    Stevens, J.G.5
  • 15
    • 0024077236 scopus 로고
    • A herpes simplex virus transcript abundant in latently infected neurons is dispensable for establishment of the latent state
    • Javier, R. T., J. G. Stevens, V. B. Dissette, and E. K. Wagner. 1988. A herpes simplex virus transcript abundant in latently infected neurons is dispensable for establishment of the latent state. Virology 166:254-257.
    • (1988) Virology , vol.166 , pp. 254-257
    • Javier, R.T.1    Stevens, J.G.2    Dissette, V.B.3    Wagner, E.K.4
  • 16
    • 0026526728 scopus 로고
    • A CT promoter element binding protein: Definition of a double-strand and a novel-strand DNA binding motif
    • Kolluri, R., T. A. Torrey, and A. J. Kinniburgh. 1992. A CT promoter element binding protein: definition of a double-strand and a novel-strand DNA binding motif. Nucleic Acids Res. 20:111-116.
    • (1992) Nucleic Acids Res. , vol.20 , pp. 111-116
    • Kolluri, R.1    Torrey, T.A.2    Kinniburgh, A.J.3
  • 17
    • 0028928894 scopus 로고
    • Expression of the herpes simplex virus type 2 latency-associated transcript enhances spontaneous reactivation of genital herpes in latently infected guinea pigs
    • Krause, P. R., N. Bourne, B. Connelly, J. F. Kurawadwala, A. Patel, L. R. Stanberry, and S. E. Straus. 1995. Expression of the herpes simplex virus type 2 latency-associated transcript enhances spontaneous reactivation of genital herpes in latently infected guinea pigs J. Exp. Med. 181:297-306.
    • (1995) J. Exp. Med. , vol.181 , pp. 297-306
    • Krause, P.R.1    Bourne, N.2    Connelly, B.3    Kurawadwala, J.F.4    Patel, A.5    Stanberry, L.R.6    Straus, S.E.7
  • 18
    • 0024209360 scopus 로고
    • Detection and preliminary characterization of herpes simplex virus type 1 transcripts in latently infected human trigeminal ganglia
    • Krause, P. R., K. D. Croen, J. M. Ostrove, and S. E. Straus. 1988. Detection and preliminary characterization of herpes simplex virus type 1 transcripts in latently infected human trigeminal ganglia J. Virol. 62:4819-4823.
    • (1988) J. Virol. , vol.62 , pp. 4819-4823
    • Krause, P.R.1    Croen, K.D.2    Ostrove, J.M.3    Straus, S.E.4
  • 19
    • 0025995702 scopus 로고
    • The nucleotide sequence. 5′ end, promoter domain, and kinetics of expression of the gene encoding the herpes simplex virus type 2 latency-associated transcript
    • Krause, P. R., J. M. Ostrove, and S. E. Straus. 1991 The nucleotide sequence. 5′ end, promoter domain, and kinetics of expression of the gene encoding the herpes simplex virus type 2 latency-associated transcript. J. Virol. 65:5619-5623.
    • (1991) J. Virol. , vol.65 , pp. 5619-5623
    • Krause, P.R.1    Ostrove, J.M.2    Straus, S.E.3
  • 20
    • 0023226177 scopus 로고
    • Recurrences after oral and genital herpes simplex virus infection influence of site of infection and viral type
    • Lafferty, W. E., R. W. Coombs, J. Benedetti, C. Critchlow, and L. Corey. 1987 Recurrences after oral and genital herpes simplex virus infection influence of site of infection and viral type. N. Engl. J. Med. 316:1444-1449
    • (1987) N. Engl. J. Med. , vol.316 , pp. 1444-1449
    • Lafferty, W.E.1    Coombs, R.W.2    Benedetti, J.3    Critchlow, C.4    Corey, L.5
  • 21
    • 0024312746 scopus 로고
    • A deletion mutant of the latency-associated transcript of herpes simplex virus type 1 reactivates from the latent state with reduced frequency
    • Leib, D. A., C. L. Bogard, M. Kosz-Vnenchak, K. A. Hicks, D. M. Coen, D. M. Knipe, and P. A. Schaffer. 1989. A deletion mutant of the latency-associated transcript of herpes simplex virus type 1 reactivates from the latent state with reduced frequency. J Virol 63:2893-2900.
    • (1989) J Virol , vol.63 , pp. 2893-2900
    • Leib, D.A.1    Bogard, C.L.2    Kosz-Vnenchak, M.3    Hicks, K.A.4    Coen, D.M.5    Knipe, D.M.6    Schaffer, P.A.7
  • 22
    • 0028032995 scopus 로고
    • Long-term promoter activity during herpes simplex virus latency
    • Lokensgard, J. R., D. C. Bloom, A. T. Dobson, and L. T. Feldman. 1994. Long-term promoter activity during herpes simplex virus latency. J. Virol. 68:7148-7158.
    • (1994) J. Virol. , vol.68 , pp. 7148-7158
    • Lokensgard, J.R.1    Bloom, D.C.2    Dobson, A.T.3    Feldman, L.T.4
  • 23
    • 0028077278 scopus 로고
    • Analysis of a herpes simplex virus type 1 LAT mutant with a deletion between the putative promoter and the 5′ end of the 2.0-kilobase transcript
    • Maggioncalda, J., A. Mehta, N. W. Fraser, and T. M. Block. 1994. Analysis of a herpes simplex virus type 1 LAT mutant with a deletion between the putative promoter and the 5′ end of the 2.0-kilobase transcript. J. Virol. 68:7816-7824.
    • (1994) J. Virol. , vol.68 , pp. 7816-7824
    • Maggioncalda, J.1    Mehta, A.2    Fraser, N.W.3    Block, T.M.4
  • 24
    • 0025173023 scopus 로고
    • Characterization of herpes simplex virus type 2 transcription during latent infection of mouse trigeminal ganglia
    • Mitchell, W. J., S. L. Deshmane, A. Dolan, D. J. McGeoch, and N. W. Fraser. 1990. Characterization of herpes simplex virus type 2 transcription during latent infection of mouse trigeminal ganglia. J. Virol. 64:5342-5348.
    • (1990) J. Virol. , vol.64 , pp. 5342-5348
    • Mitchell, W.J.1    Deshmane, S.L.2    Dolan, A.3    McGeoch, D.J.4    Fraser, N.W.5
  • 25
    • 0026333513 scopus 로고
    • Comparative sequence analysis of the long repeat regions and adjoining parts of the long unique regions in the genomes of herpes simplex viruses types 1 and 2
    • McGeoch, D. J., C. Cunningham, G. McIntyre, and A. Dolan. 1991 Comparative sequence analysis of the long repeat regions and adjoining parts of the long unique regions in the genomes of herpes simplex viruses types 1 and 2. J. Gen. Virol 72:3057-3075.
    • (1991) J. Gen. Virol , vol.72 , pp. 3057-3075
    • McGeoch, D.J.1    Cunningham, C.2    McIntyre, G.3    Dolan, A.4
  • 26
    • 0027496350 scopus 로고
    • Herpes simplex virus type 1 latency-associated transcript (LAT) promoter deletion mutants, can express a 2-kilobase transcript mapping to the LAT region
    • Nicosia, M., S. L. Deshmane, T. Zabolotny, T. Valyi-Nagy, and N. W. Fraser. 1993. Herpes simplex virus type 1 latency-associated transcript (LAT) promoter deletion mutants, can express a 2-kilobase transcript mapping to the LAT region. J. Virol. 67:7276-7283
    • (1993) J. Virol. , vol.67 , pp. 7276-7283
    • Nicosia, M.1    Deshmane, S.L.2    Zabolotny, T.3    Valyi-Nagy, T.4    Fraser, N.W.5
  • 27
    • 0027186444 scopus 로고
    • In vivo characterization of site-directed mutations in the promoter of the herpes simplex virus type 1 latency-associated transcripts
    • Rader, K. A., C. E. Ackland-Berglund, J. K. Miller, J. S. Pepose, and D. A. Leib. 1993. In vivo characterization of site-directed mutations in the promoter of the herpes simplex virus type 1 latency-associated transcripts. J. Gen Virol. 74:1859-1869.
    • (1993) J. Gen Virol. , vol.74 , pp. 1859-1869
    • Rader, K.A.1    Ackland-Berglund, C.E.2    Miller, J.K.3    Pepose, J.S.4    Leib, D.A.5
  • 28
    • 0026583838 scopus 로고
    • Herpes simplex virus type 1 latency-associated transcription unit promotes anatomical site-dependent establishment and reactivation from latency
    • Sawtell, N. M., and R. L. Thompson, 1992. Herpes simplex virus type 1 latency-associated transcription unit promotes anatomical site-dependent establishment and reactivation from latency. J. Virol. 66:2157-2169
    • (1992) J. Virol. , vol.66 , pp. 2157-2169
    • Sawtell, N.M.1    Thompson, R.L.2
  • 29
    • 0027321358 scopus 로고
    • Transcriptional analysis of the herpes simplex virus type 1 region containing the TRL/UL junction
    • Singh, J., and E. K. Wagner. 1993. Transcriptional analysis of the herpes simplex virus type 1 region containing the TRL/UL junction Virology 196:220-231.
    • (1993) Virology , vol.196 , pp. 220-231
    • Singh, J.1    Wagner, E.K.2
  • 30
    • 0023472243 scopus 로고
    • Detection of herpes simplex virus type 1 transcripts during latent infection in mice
    • Spivack, J. G., and N. W. Fraser. 1988 Detection of herpes simplex virus type 1 transcripts during latent infection in mice J Virol 61:3841-3847.
    • (1988) J Virol , vol.61 , pp. 3841-3847
    • Spivack, J.G.1    Fraser, N.W.2
  • 31
    • 0028002276 scopus 로고
    • Animal models and HSV latency
    • Stanberry, L. R. 1994. Animal models and HSV latency. Semin. Virol. 5:213-219.
    • (1994) Semin. Virol. , vol.5 , pp. 213-219
    • Stanberry, L.R.1
  • 32
    • 0019966496 scopus 로고
    • Genital herpes in guinea pigs: Pathogenesis of the primary infection and the description of recurrent disease
    • Stanberry, L. R., E. R. Kern, J. T. Richards, T. M. Abbott, and J. C. Overall, Jr. 1984. Genital herpes in guinea pigs: pathogenesis of the primary infection and the description of recurrent disease. J. Infect. Dis. 146:391-404.
    • (1984) J. Infect. Dis. , vol.146 , pp. 391-404
    • Stanberry, L.R.1    Kern, E.R.2    Richards, J.T.3    Abbott, T.M.4    Overall Jr., J.C.5
  • 35
    • 0023140228 scopus 로고
    • RNA complementary to a herpesvirus alpha gene mRNA is prominent in latently infected mice
    • Stevens, J. G., E. K. Wagner, G. Devi-Rao, M. Cook, and L. T. Feldman. 1987. RNA complementary to a herpesvirus alpha gene mRNA is prominent in latently infected mice. Science 235:1056-1059
    • (1987) Science , vol.235 , pp. 1056-1059
    • Stevens, J.G.1    Wagner, E.K.2    Devi-Rao, G.3    Cook, M.4    Feldman, L.T.5
  • 36
    • 0025789629 scopus 로고
    • In vivo and in vitro reactivation impairment of a herpes simplex virus type 1 latency-associated transcript variant in a rabbit eye model
    • Trousdale, M. D., I. Steiner, J. G. Spivack, S. L. Deshmane, S. M. Brown, A. R. MacLean, J. H. Subak-Sharpe, and N. W. Fraser. 1991. In vivo and in vitro reactivation impairment of a herpes simplex virus type 1 latency-associated transcript variant in a rabbit eye model. J. Virol. 65:6989-6993.
    • (1991) J. Virol. , vol.65 , pp. 6989-6993
    • Trousdale, M.D.1    Steiner, I.2    Spivack, J.G.3    Deshmane, S.L.4    Brown, S.M.5    MacLean, A.R.6    Subak-Sharpe, J.H.7    Fraser, N.W.8
  • 38
    • 0024205630 scopus 로고
    • The herpes simplex virus latency-associated transcript is spliced during the latent phase of infection
    • Wagner, E. K., W. M. Flanagan, G. Devi Rao, Y.-F. Zhang, J. M. Hill, K. P. Anderson, and J. G. Stevens. 1988. The herpes simplex virus latency-associated transcript is spliced during the latent phase of infection. J. Virol. 62:4577-4585
    • (1988) J. Virol. , vol.62 , pp. 4577-4585
    • Wagner, E.K.1    Flanagan, W.M.2    Devi Rao, G.3    Zhang, Y.-F.4    Hill, J.M.5    Anderson, K.P.6    Stevens, J.G.7
  • 39
    • 0028951651 scopus 로고
    • Analysis of the promoter and cis-acting elements regulating expression of herpes simplex virus type 2 latency-associated transcripts
    • Wang, K., P. R. Krause, and S. E. Straus. 1995. Analysis of the promoter and cis-acting elements regulating expression of herpes simplex virus type 2 latency-associated transcripts. J. Virol. 69:2873-2880.
    • (1995) J. Virol. , vol.69 , pp. 2873-2880
    • Wang, K.1    Krause, P.R.2    Straus, S.E.3
  • 40
    • 0024230295 scopus 로고
    • Fine mapping of the major latency-related gene of herpes simplex virus type 1 in humans
    • Wechsler, S. L., A. B. Nesburn, R. Watson, S. Slanina, and H. Ghiasi. 1988 Fine mapping of the major latency-related gene of herpes simplex virus type 1 in humans. J Gen Virol 69:3101-3106.
    • (1988) J Gen Virol , vol.69 , pp. 3101-3106
    • Wechsler, S.L.1    Nesburn, A.B.2    Watson, R.3    Slanina, S.4    Ghiasi, H.5
  • 41
    • 0023774515 scopus 로고
    • Fine mapping of the latency-related gene of herpes simplex virus type 1: Alternative splicing produces distinct latency-related open reading frames
    • Wechsler, S. L., A. B. Nesburn, R. Watson, S. M. Slanina, and H. Ghiasi. 1988. Fine mapping of the latency-related gene of herpes simplex virus type 1: alternative splicing produces distinct latency-related open reading frames. J Virol. 62:4051-4058.
    • (1988) J Virol. , vol.62 , pp. 4051-4058
    • Wechsler, S.L.1    Nesburn, A.B.2    Watson, R.3    Slanina, S.M.4    Ghiasi, H.5
  • 42
    • 0025048749 scopus 로고
    • Activity of herpes simplex virus type 1 latency associated transcript promoter in neuron-derived cells, evidence for neuron specificity and for a large LAT transcript
    • Zwaagstra, J., H. Ghiasi, S. M. Slanina, A. B. Nesburn, S. C. Wheatley, K. Lillycrop, J. Wood, D. S. Latchman, K. Patel, and S. L. Wechsler. 1990. Activity of herpes simplex virus type 1 latency associated transcript promoter in neuron-derived cells, evidence for neuron specificity and for a large LAT transcript. J. Virol. 64:5019-5028.
    • (1990) J. Virol. , vol.64 , pp. 5019-5028
    • Zwaagstra, J.1    Ghiasi, H.2    Slanina, S.M.3    Nesburn, A.B.4    Wheatley, S.C.5    Lillycrop, K.6    Wood, J.7    Latchman, D.S.8    Patel, K.9    Wechsler, S.L.10
  • 43
    • 0025897495 scopus 로고
    • Identification of a major regulatory sequence in the latency associated transcript (LAT) promoter of herpes simplex virus type 1 (HSV-1)
    • Zwaagstra, J. C., H. Ghiasi, A. B. Nesburn, and S. L. Wechsler. 1991. Identification of a major regulatory sequence in the latency associated transcript (LAT) promoter of herpes simplex virus type 1 (HSV-1). Virology 182:287-297.
    • (1991) Virology , vol.182 , pp. 287-297
    • Zwaagstra, J.C.1    Ghiasi, H.2    Nesburn, A.B.3    Wechsler, S.L.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.