Glucocorticoids regulate glutamine synthetase expression in lung epithelial cells

American Journal of Physiology - Lung Cellular and Molecular Physiology

Volumn 270, Issue 1 14-1, 1996, Pages

  Abcouwer, Steve F ^a   Lukaszewicz, Gregory C ^a   Souba, Wiley W ^a,b  

^a HARVARD MEDICAL SCHOOL   (United States)

^b MASSACHUSETTS GENERAL HOSPITAL   (United States)

Author keywords

cycloheximide; dexamethasone; L2 cells; messenger ribonucleic acid stability; sepsis

Indexed keywords

COMPLEMENT COMPONENT C5; CYCLOHEXIMIDE; CYTOKINE; DACTINOMYCIN; DEXAMETHASONE; ESCHERICHIA COLI LIPOPOLYSACCHARIDE; GLUCOCORTICOID; GLUCOCORTICOID RECEPTOR; GLUTAMATE AMMONIA LIGASE; MESSENGER RNA; MIFEPRISTONE; PROSTAGLANDIN;

ARTICLE; ENZYME ACTIVITY; GENE EXPRESSION REGULATION; HUMAN; HUMAN CELL; LUNG ALVEOLUS EPITHELIUM; PRIORITY JOURNAL; REGULATORY MECHANISM; SEPSIS; SEPTIC SHOCK;

EID: 0030067430     PISSN: 10400605     EISSN: None     Source Type: Journal    
DOI: 10.1152/ajplung.1996.270.1.l141     Document Type: Article

References (47)

1. Abcouwer, S. F., B. P. Bode, and W. W. Souba. Glucocorticoids regulate glutamine synthetase expression in a tissue-specific manner. J. Surg. Res. 59: 59-65, 1995.
2. Aiba, M., A. Hirayama, M. Sakurada, and T. Suzuki. Socalled sclerosing hemangioma of the lung with nuclear inclusion bodies. Immunohistochemical study of a case. Acta Pathol. Jpn. 38: 873-881, 1988.
3. Altus, M. S., and Y. Nagamine. Protein synthesis inhibition stabilizes urokinase-type plasminogen activator mRNA. J. Biol. Chem. 266: 21190-21196, 1991.
4. Ardawi, M. S. M. Glutamine and alamne metabolism in the lungs of septic rats. Clin. Sci. 81: 603-609, 1991.
5. Ardawi, M. S. M. Glutamme metabolism in the lungs of glucorticoid-treated rats. Clin. Sci. 81: 37-42, 1991.
6. Ardawi, M. S. M. Glutamine-synthesizing activity in lungs of fed, starved, acidotic, diabetic, injured and septic rats. Biochem. J. 270: 829-832, 1985.
7. Ballard, P. L. Glucocorticoid receptors in the lung. Federation Proc. 36: 2660-2665, 1977.
8. Bhandari, B., and R. E. Miller. Glutamine synthetase gene transcription in cultured 3T3-L1 adipocytes: regulation by dexamethasone, insulin and dibutyryl cyclic AMP. Mol. Cell. Endocrinol. 51: 7-11, 1987.
9. Calvalieri, R. L., E. A. Havel, J. Vilcek, and S. Pestka. Induction and decay of human fibroblast interferon mRNA. Proc. Natl. Acad. Sci USA 74: 4415-4419, 1977.
10. Chomcynski, P., and N. Sacchi. Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction. Anal. Biochem. 162: 156-159, 1987.
11. Crook, R. B., M. Louie, T. P. Deuel, and G. M. Tompkins. Regulation of glutamine synthetase by dexamethasone in hepatoma tissue culture cells. J. Biol. Chem. 253: 6125-6131, 1978.
12. Douglas, W. H., S. K. Sommers-Smith, and J. M. Johnson. Phoshatidate phosphohydrolase activity as a marker for surfactant synthesis in organotypic cultures of type II alveolar pneumonocytes. J. Cell. Sci. 60: 199-207, 1983.
13. Edwards, D. R., and L. C. Mahadevan. Protein synthesis inhibitors differentially superinduce c-fos and c-jun by three distinct mechanisms: lack of evidence for labile repressors. EMBO J. 11: 2415-2424, 1992.
14. Fahrner, J., W. T. Labruyere, C. Gaunitz, A. F. Moorman, R. Gebhardt, and W. H. Lamers. Identification and functional characterization of regulatory elements of the glutamine synthetase gene from rat liver. Eur. J. Biochem. 213: 1067-1073, 1993.
15. Feng, B., D. C. Hilt, and S. R. Max. Transcriptional regulation of glutamine synthetase gene expression by dexamethasone in L6 muscle cells. J. Biol. Chem. 265: 18702-18706, 1990.
16. Fressinaud, C., H. Weinrauder, J.-P. Delaunoy, G. Tholey, G. Labourette, and L. L. Sarlieve. Glutamine synthetase expression in rat oligodendrocytes in culture: regulation by hormones and growth factors. J. Cell. Physiol. 149: 459-468, 1991.
17. Gagne, D., M. Pons, and D. Philibert. RU-38486: a potent antiglucocorticoid in vitro and in vivo. J. Steroid Biochem. 23: 247-251, 1985.
18. Garfield, S., and A. A. Moscona. Experimental conservation and delayed expression of labile templates for enzyme synthesis in neural cells. Biochem. Biophys. Res. Commun. 51: 718-724, 1973.
19. Gebhart, R., and D. Mecke. The role of growth hormone, dexamethasone and triiodothyronine in the regulation of glutamine synthetase in primary cultures of rat hepatocytes. Eur. J. Biochem. 100: 519-525, 1979.
20. Hargrove, J. L., M. G. Hulsey, and E. G. Beale. The kinetics of mammalian gene expression. BioEssays 13: 667-674, 1992.
21. Harmon, J. M., and E. B. Thompson. Glucocorticoid synthetase induction by glucocorticoids in the glucocorticoid-sensitive human leukemic cell line CEM-C7. J. Cell. Physiol. 110: 155-160, 1982.
22. Heinrich, P. C., J. V. Castell, and T. Andus. Interleukin-6 and the acute phase response. Biochem. J. 265: 621-636, 1990.
23. Kaign, M. E., and W. H. J. Douglas. Isolation of clonal lines from normal rat lung with lung-specific properties (Abstract). Cell. Biol. 59: 160A, 1973.
24. Laping, N. J., N. R. Nichols, J. R. Day, S. A. Johnson, and C. E. Finch. Transcriptional control of glial fibrillary acidic protein and glutamine synthetase in vivo shows opposite responses to corticosterone in the hippocampus. Endocrinolology 135: 1928-1933, 1994.
25. Lau, L. F., and D. Nathans. Expression of a set of growth-related immediate early genes in BALB/c 3T3 cells: coordinant regulation with c-fos and c-myc. Proc. Natl. Acad. Sci. USA 84: 1182-1186, 1987.
26. Max, S. R., J. Mill, K. Mearow, M. Konagaya, Y. Konagaya. J. W. Thomas, C. Banner, and L. Vitkovic. Dexamethasone regulates glutamine synthetase expression in rat skeletal muscles. Am. J. Physiol. 255 (Endocrinol. Metab. 18): E397-E403, 1988.
27. Max, S. R., J. W. Thomas, C. Banner, L. Vitkovic, M. Konagaya, and Y. Konagaya. Glucocorticoid receptor-mediated induction of glutamine synthetase in skeletal muscle cells in vitro. Endocrinology 120: 1179-1183, 1987.
28. Mill, J. F., K. M. Mearow, H. J. Purohit, H. Haleem-Smith, R. King, and E. Freese. Cloning and functional characterization of the rat glutamine synthetase gene. Mol. Brain Res. 9: 197-207, 1991.
29. Müllner, E. W., and L. C. Kühn. A stem-loop in the 3′ untranslated region mediates iron-dependent regulation of transferrin receptor mRNA stability in the cytoplasm. Cell 53: 815-825, 1988.
30. Patejunas, G., and A. P. Young. Constitutive and glucocorticoid-mediated activation of glutamine synthetase expression in the developing chicken retina. J. Biol. Chem. 265: 15280-15285, 1990.
31. Patel, A. J., and A. Hunt. Observations on cell growth and regulation of glutamine synthetase by dexamethasone in primary cultures of forebrain and cerebral astrocytes. Develop. Brain Res. 18: 175-184, 1985.
32. Perretti, M., G. S. Duncan, R. J. Flower, and S. H. Peers. Serum corticosterone, interleukin-1 and tumour necrosis factor in rat experimental endotoxaemia: comparison between Lewis and Wister strains. Br. J. Pharmacol. 110: 868-874, 1993.
33. Plumley, D. A., W. W. Souba, R. D. Hautamaki, T. D. Martin, T. C. Flinn, W. R. Ront, and E. M. Copeland III. Accelerated lung amino acid release in hyperdynamic septic surgical patients. Arch. Surg. 125: 57-61, 1990.
34. Saini, K., P. Thomas, and B. Bhandari. Hormonal regulation of stability of glutamine synthetase mRNA in cultured 3T3-L1 adipocytes. Biochem. J. 267: 241-244, 1990.
35. Salem, M., R. E. Tainsh, J. Bromberg, D. L. Loreaux, and B. Chernow. Perioperative glucocorticoid coverage. A reassessment 42 years after emergence of a problem. Ann. Surg. 219: 416-425, 1994.
36. Sambrook, J., R. F. Fritsh, and R. Maniatis. Molecular Cloning: A Laboratory Manual. Cold Spring Harbor, NY: Cold Spring Harbor Laboratory, 1989.
37. Sandrasagra, A., G. Patejunas, and A. P. Young. Multiple mechanisms by which glutamine synthetase levels are controlled in murine tissue culture cells. Arch. Biochem. Biophys. 266: 522-531, 1988.
38. Sarantos, P., D. Howard, and W. W. Souba. Dexamethasone regulates glutamine synthetase expression in rat lung. Metabolism 42: 795-800, 1993.
39. Sarkar, P. K., and S. Chaudhury. Messenger RNA for glutamine synthetase. Mol. Cell. Biochem. 53/54: 233-244, 1983.
40. Schwartz, M. L., P. S. Shneidman, J. Bruce, and W. W. Schlaepfer. Actinomycin prevents the destabilization of neurofilament mRNA in primary sensory neurons. J. Biol. Chem. 267: 24596-24600, 1992
41. Shyu, A.-B., M. E. Greenberg, and J. G. Belasco. The c-fos transcript is targeted for rapid decay by two distinct mRNA degradation pathways. Genes Develop. 3: 60-72, 1989.
42. Smith, R. J., S. Larson, S. E. Stred, and R. P. Durschlag. Regulation of glutamine synthetase and glutaminase activities in cultured skeletal muscle cells. J. Cell. Physiol. 120: 197-203, 1984.
43. Souba, W. W., and T. R. Austgen. Interorgan glutamine flow following surgery and infection. J. Parenter. Enter. Nutr. 14 Suppl.: 90S-93S, 1990.
44. Souba, W. W., D. A. Plumley, R. M. Salloum, and E. M. Copeland. Effects of glucocorticoids on lung glutamine and alanine metabolism. Surgery 108: 213-219, 1990.
45. Vardimon, L., L. L. Fox, L. Degenstein, and A. A. Moscona. Cell contacts are required for induction by cortisol of glutamine synthetase gene transcription in the retina Proc. Natl. Acad. Sci. USA 85: 5981-5985, 1988.
46. Wisdom, R., and W. Lee. The protein-coding region of c-myc mRNA contains a sequence that specifies rapid mRNA turnover and induction by protein synthesis inhibitors. Genes Develop. 5: 232-243, 1991.
47. Zhang, H., and A. P. Young. A single upstream glucocorticoid response element juxaposed to an AP1/ATF/CRE-like site renders the chicken glutamine synthetase gene hormonally inducible in transfected retina. J. Biol. Chem. 266: 24332-24338, 1991.