Synthesis of propane-2,3-diol combinatorial monomers

Tetrahedron Letters

Volumn 37, Issue 23, 1996, Pages 3931-3934

  Acevedo, Oscar L ^a   Andrews, Robert S ^a  

^a ISIS PHARMACEUTICALS   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

PHOSPHORAMIDIC ACID DERIVATIVE; PURINE DERIVATIVE;

ARTICLE; CATALYSIS; DRUG SYNTHESIS; REACTION ANALYSIS;

EID: 0030067393     PISSN: 00404039     EISSN: None     Source Type: Journal    
DOI: 10.1016/0040-4039(96)00745-9     Document Type: Article

References (18)

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5. Amplification methods using PCR or T-7 RNA polymerases have used modified pyrimidines as substrates. See: Latham, J.A., Johnson, R. and Toole, J.J. Nucleic Acids Research 1994, 14, 2817-2822; Dewey, T.M., Mundt, A.A., Crouch, G.J., Zyzniewski, M.C. and Eaton, B.E. J. Am. Chem. Soc. 1995, 117, 8474-8475.
6. Amplification methods using PCR or T-7 RNA polymerases have used modified pyrimidines as substrates. See: Latham, J.A., Johnson, R. and Toole, J.J. Nucleic Acids Research 1994, 14, 2817-2822; Dewey, T.M., Mundt, A.A., Crouch, G.J., Zyzniewski, M.C. and Eaton, B.E. J. Am. Chem. Soc. 1995, 117, 8474-8475.
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8. Wyatt, J.R., Vickers, T.A., Roberson, J.L., Buckheit, R.W., Jr., Klimkait, T., DeBaets, E., Davis, P.W., Rayner, B., Imbach, J.L. and Ecker, D.J. Proc. Natl. Acad. Sci. USA 1994, 91, 1356-1360.
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10. 2O); 6.9, 7.1, and 7.6 (3 s, 3, imidazole).
11. Ueda, N. J. Heterocylic Chem. 1971, 9, 827-829.
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13. 2O); 6.2 (s, 1, thymine); 11.2 (bs, 1, NH).
14. Jones, R. A. "Preparation of Protected Deoxyribonucleotides" in Oligonucletide Synthesis: A Practical Approach", Gait, M.J. ed., IRL Press, 1985, Chapter 2.
15. 3); 6.9 and 7.3 (m, 13, aryl).
16. 2O); 3.7-3.8 (m, 7, dimethoxy and methine); 6.9-7.5 (2 m, 13, aryl).
17. Kenan, D.J., Tsai, D.E. and Keene, J.D. Trends in Biochemical Sciences 1994, 19, 57-64.
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