-
1
-
-
0026071588
-
Scid mutation in mice confers hypersensitivity to ionizing radiation and a deficiency in DNA double-strand break repair
-
K. A. Biedermann, J. Sun, A. J. Giaccia, L. M. Tosto and J. M. Brown, Scid mutation in mice confers hypersensitivity to ionizing radiation and a deficiency in DNA double-strand break repair. Proc. Natl. Acad. Sci. USA 88, 1394-1397 (1991).
-
(1991)
Proc. Natl. Acad. Sci. USA
, vol.88
, pp. 1394-1397
-
-
Biedermann, K.A.1
Sun, J.2
Giaccia, A.J.3
Tosto, L.M.4
Brown, J.M.5
-
2
-
-
0025011134
-
The scid mutation in mice causes a general defect in DNA repair
-
G. M. Fulop and R. A. Phillips, The scid mutation in mice causes a general defect in DNA repair. Nature 347, 479-482 (1990).
-
(1990)
Nature
, vol.347
, pp. 479-482
-
-
Fulop, G.M.1
Phillips, R.A.2
-
3
-
-
0025778519
-
A link between double-strand break-related repair and V(D)J recombination: The seid mutation
-
E. A. Hendrickson, X. Q. Qin, E. A. Bump, D. G. Schatz, M. Oettinger and D. T. Weaver, A link between double-strand break-related repair and V(D)J recombination: the seid mutation. Proc. Natl. Acad. Sci. USA 88, 4061-W65 (1991).
-
(1991)
Proc. Natl. Acad. Sci. USA
, vol.88
-
-
Hendrickson, E.A.1
Qin, X.Q.2
Bump, E.A.3
Schatz, D.G.4
Oettinger, M.5
Weaver, D.T.6
-
4
-
-
0027512522
-
Characterization of the DNA double strand break repair defect in scid mice
-
C. Chang, A. Biedermann, K. M. Mezzina and J M. Brown, Characterization of the DNA double strand break repair defect in scid mice. Cancer Res. 53, 1244-1248 (1993).
-
(1993)
Cancer Res.
, vol.53
, pp. 1244-1248
-
-
Chang, C.1
Biedermann, A.2
Mezzina, K.M.3
Brown, J.M.4
-
5
-
-
0023026643
-
Rearrangement of antigen receptor genes is defective in mice with severe combined immune deficiency
-
W. Schuler, I. J. Weiler, A. Schuler, R. A. Phillips, N. Rosenberg, T. W. Mak, J. F. Kearney, R. P. Perry and M. J. Bosma, Rearrangement of antigen receptor genes is defective in mice with severe combined immune deficiency. Cell 46, 963-972 (1986).
-
(1986)
Cell
, vol.46
, pp. 963-972
-
-
Schuler, W.1
Weiler, I.J.2
Schuler, A.3
Phillips, R.A.4
Rosenberg, N.5
Mak, T.W.6
Kearney, J.F.7
Perry, R.P.8
Bosma, M.J.9
-
6
-
-
0023801238
-
The defect in murine severe combined immune deficiency: Joining of signal sequences but not coding segments in V(D)J recombination
-
M. R. Lieber, J. E. Hesse, S. Lewis, G. C. Bosma, N. Rosenberg, K. Mizuuchi, M. J. Bosma and M. Gellert, The defect in murine severe combined immune deficiency: joining of signal sequences but not coding segments in V(D)J recombination. Cell 55, 7-16 (1988).
-
(1988)
Cell
, vol.55
, pp. 7-16
-
-
Lieber, M.R.1
Hesse, J.E.2
Lewis, S.3
Bosma, G.C.4
Rosenberg, N.5
Mizuuchi, K.6
Bosma, M.J.7
Gellert, M.8
-
7
-
-
0023792756
-
The scid defect affects the final step of the immunoglobulin VDJ recombinase mechanism
-
B. A. Malynn, T. K. Blackwell, G. M. Fulop, G. A. Rathbun, A. J. Furley, P. Ferner, L. B. Heinke, R. A. Phillips, G. D. Yancopoulos and F. W. Alt. The scid defect affects the final step of the immunoglobulin VDJ recombinase mechanism. Cell 54, 453-460 (1988).
-
(1988)
Cell
, vol.54
, pp. 453-460
-
-
Malynn, B.A.1
Blackwell, T.K.2
Fulop, G.M.3
Rathbun, G.A.4
Furley, A.J.5
Ferner, P.6
Heinke, L.B.7
Phillips, R.A.8
Yancopoulos, G.D.9
Alt, F.W.10
-
8
-
-
0024052153
-
The scid gene encodes a trans-acting factor that mediates the rejoining event of Ig gene rearrangement
-
E. A. Hendrickson, D. G. Schatz and D. T. Weaver, The scid gene encodes a trans-acting factor that mediates the rejoining event of Ig gene rearrangement. Genes Dev. 2, 817-829 (1988).
-
(1988)
Genes Dev.
, vol.2
, pp. 817-829
-
-
Hendrickson, E.A.1
Schatz, D.G.2
Weaver, D.T.3
-
9
-
-
0027245559
-
V(D)J recombination in mammalian cell mutants defective in DNA double-strand break repair
-
F. Pergola, M. Z. Zdzienicka and M. R. Lieber, V(D)J recombination in mammalian cell mutants defective in DNA double-strand break repair. Mol. Cell. Biol. 13, 3464-3471 (1993).
-
(1993)
Mol. Cell. Biol.
, vol.13
, pp. 3464-3471
-
-
Pergola, F.1
Zdzienicka, M.Z.2
Lieber, M.R.3
-
10
-
-
0027156278
-
Impairment of V(D)J recombination in double-strand repair mutants
-
G. E. Taccioli, G. Rathbun, E. Oltz, T. Stamato, P. A. Jeggo and F. W. Alt. Impairment of V(D)J recombination in double-strand repair mutants. Science 260, 207-210 (1993).
-
(1993)
Science
, vol.260
, pp. 207-210
-
-
Taccioli, G.E.1
Rathbun, G.2
Oltz, E.3
Stamato, T.4
Jeggo, P.A.5
Alt, F.W.6
-
11
-
-
0028960511
-
Defective DNA-dependent protein kinase activity is linked to V(D)J recombination and DNA repair defects associated with the murine scid mutation
-
T. Blunt, N. J. Finnie, G. E. Taccioli, G. C. Smith, J. Demengeot, T. M. Gottlieb, R. Mizuta, A. J. Varghese, F. W. Alt and P. A. Jeggo, Defective DNA-dependent protein kinase activity is linked to V(D)J recombination and DNA repair defects associated with the murine scid mutation. Cell 80, 813-823 (1995).
-
(1995)
Cell
, vol.80
, pp. 813-823
-
-
Blunt, T.1
Finnie, N.J.2
Taccioli, G.E.3
Smith, G.C.4
Demengeot, J.5
Gottlieb, T.M.6
Mizuta, R.7
Varghese, A.J.8
Alt, F.W.9
Jeggo, P.A.10
-
12
-
-
0028953951
-
DNA-dependent kinase (p350) as a candidate gene for the murine SCID defect
-
C. U. Kirchgessner, C. K. Patil, J. W. Evans, C. A. Cuomo, L. M. Fried, T. Carter, M. A. Oettinger and J. M. Brown, DNA-dependent kinase (p350) as a candidate gene for the murine SCID defect. Science 267, 1178-1183 (1995).
-
(1995)
Science
, vol.267
, pp. 1178-1183
-
-
Kirchgessner, C.U.1
Patil, C.K.2
Evans, J.W.3
Cuomo, C.A.4
Fried, L.M.5
Carter, T.6
Oettinger, M.A.7
Brown, J.M.8
-
13
-
-
0028902932
-
Loss of the catalytic subunit of the DNA-dependent protein kinase in DNA double-strand-break-repair mutant mammalian cells
-
S. R. Peterson, A. Kurimasa, M. Oshimura, W. S. Dynan, E. M. Bradbury and D. J. Chen, Loss of the catalytic subunit of the DNA-dependent protein kinase in DNA double-strand-break-repair mutant mammalian cells. Proc. Natl. Acad. Sci. USA 92, 3171-3174 (1995).
-
(1995)
Proc. Natl. Acad. Sci. USA
, vol.92
, pp. 3171-3174
-
-
Peterson, S.R.1
Kurimasa, A.2
Oshimura, M.3
Dynan, W.S.4
Bradbury, E.M.5
Chen, D.J.6
-
14
-
-
0028112944
-
Restoration of X-ray resistance and V(D)J recombination in mutant cells by Ku cDNA
-
V. Smider, W. K. Rathmell, M. R. Lieber and G. Chu, Restoration of X-ray resistance and V(D)J recombination in mutant cells by Ku cDNA. Science 266, 288-291 (1994).
-
(1994)
Science
, vol.266
, pp. 288-291
-
-
Smider, V.1
Rathmell, W.K.2
Lieber, M.R.3
Chu, G.4
-
15
-
-
0028025020
-
Ku80: Product of the XRCC5 gene and its role in DNA repair and V(D)J recombination
-
G. E. Taccioli, T. M. Gottlieb, T. Blunt, A. Priestley, J. Demengeot, R. Mizuta, A. R. Lehmann, F. W. Alt, S. P. Jackson and P. A. Jeggo, Ku80: product of the XRCC5 gene and its role in DNA repair and V(D)J recombination. Science 265, 1442-1445 (1994).
-
(1994)
Science
, vol.265
, pp. 1442-1445
-
-
Taccioli, G.E.1
Gottlieb, T.M.2
Blunt, T.3
Priestley, A.4
Demengeot, J.5
Mizuta, R.6
Lehmann, A.R.7
Alt, F.W.8
Jackson, S.P.9
Jeggo, P.A.10
-
16
-
-
10544220050
-
Nomenclature of human genes involved in ionizing radiation sensitivity
-
in press
-
L. H. Thompson and P. A. Jeggo, Nomenclature of human genes involved in ionizing radiation sensitivity. Mutat. Res., in press.
-
Mutat. Res.
-
-
Thompson, L.H.1
Jeggo, P.A.2
-
17
-
-
0028363754
-
Absence of a Ku-like DNA end binding activity in the xrs double-strand DNA repair-deficient mutant
-
R. C. Getts and T. D. Stamato. Absence of a Ku-like DNA end binding activity in the xrs double-strand DNA repair-deficient mutant. J. Biol. Chem. 269, 15981-15984 (1994).
-
(1994)
J. Biol. Chem.
, vol.269
, pp. 15981-15984
-
-
Getts, R.C.1
Stamato, T.D.2
-
18
-
-
0027966126
-
Involvement of the Ku autoantigen in the cellular response to DNA double-strand breaks
-
W. K. Rathmell and G. Chu, Involvement of the Ku autoantigen in the cellular response to DNA double-strand breaks. Proc. Natl. Acad. Sci. USA 91, 7623-7627 (1994).
-
(1994)
Proc. Natl. Acad. Sci. USA
, vol.91
, pp. 7623-7627
-
-
Rathmell, W.K.1
Chu, G.2
-
19
-
-
0025201179
-
A DNA-activated protein kinase from HeLa cell nuclei
-
T. Carter, I. Vancurova, I. Sun, W. Lou and S. DeLeon, A DNA-activated protein kinase from HeLa cell nuclei. Mol. Cell. Biol. 10, 6460-6471 (1990).
-
(1990)
Mol. Cell. Biol.
, vol.10
, pp. 6460-6471
-
-
Carter, T.1
Vancurova, I.2
Sun, I.3
Lou, W.4
DeLeon, S.5
-
20
-
-
0024357643
-
The human double-stranded DNA-activated protein kinase phosphorylates the 90-kDa heat-shock protein. hsp90 alpha, at two NH2-terminal threonine residues
-
M. S. Lees and C. W. Anderson, The human double-stranded DNA-activated protein kinase phosphorylates the 90-kDa heat-shock protein. hsp90 alpha, at two NH2-terminal threonine residues. J. Biol. Chem. 264, 17275-17280 (1989).
-
(1989)
J. Biol. Chem.
, vol.264
, pp. 17275-17280
-
-
Lees, M.S.1
Anderson, C.W.2
-
21
-
-
0027397867
-
The DNA-dependent protein kinase: Requirement for DNA ends and association with Ku antigen
-
T. M. Gottlieb and S. P. Jackson, The DNA-dependent protein kinase: Requirement for DNA ends and association with Ku antigen. Cell 72, 131-142 (1993).
-
(1993)
Cell
, vol.72
, pp. 131-142
-
-
Gottlieb, T.M.1
Jackson, S.P.2
-
23
-
-
0028897304
-
DNA-dependent protein kinase activity is absent in xrs-6 cells: Implications for site-specific recombination and DNA double-strand break repair
-
N. J. Finnie, T. M. Gottlieb, T. Blunt, P. A. Jeggo and S. P. Jackson, DNA-dependent protein kinase activity is absent in xrs-6 cells: implications for site-specific recombination and DNA double-strand break repair. Proc. Natl. Acad. Sci USA 92, 320-324 (1995).
-
(1995)
Proc. Natl. Acad. Sci USA
, vol.92
, pp. 320-324
-
-
Finnie, N.J.1
Gottlieb, T.M.2
Blunt, T.3
Jeggo, P.A.4
Jackson, S.P.5
-
24
-
-
0025324367
-
Production and repair of chromosome damage in an X-ray sensitive CHO mutant visualized and analyzed in interphase using the technique of premature chromosome condensation
-
G. E. Iliakis and G. E. Pantelias, Production and repair of chromosome damage in an X-ray sensitive CHO mutant visualized and analyzed in interphase using the technique of premature chromosome condensation. Int. J. Radiat. Biol. 57, 1213-1223 (1990).
-
(1990)
Int. J. Radiat. Biol.
, vol.57
, pp. 1213-1223
-
-
Iliakis, G.E.1
Pantelias, G.E.2
-
25
-
-
0027420454
-
Hypertonic treatment does not affect the radiation yield of interphase chromosome breaks in DNA double-strand break repair-deficient xrs-5 cells
-
R. Okayasu, J. Varlotto and G. Iliakis, Hypertonic treatment does not affect the radiation yield of interphase chromosome breaks in DNA double-strand break repair-deficient xrs-5 cells. Radiat. Res. 135, 171-177 (1993).
-
(1993)
Radiat. Res.
, vol.135
, pp. 171-177
-
-
Okayasu, R.1
Varlotto, J.2
Iliakis, G.3
-
26
-
-
0014959463
-
Mammalian cell fusion: Induction of premature chromosome condensation in interphase nuclei
-
R. T. Johnson and P. N. Rao, Mammalian cell fusion: induction of premature chromosome condensation in interphase nuclei. Nature 226, 717-722 (1970).
-
(1970)
Nature
, vol.226
, pp. 717-722
-
-
Johnson, R.T.1
Rao, P.N.2
-
27
-
-
0021037997
-
High-resolution measurement of breaks in prematurely condensed chromosomes by differential staining
-
M. N. Cornforth and J. S. Bedford, High-resolution measurement of breaks in prematurely condensed chromosomes by differential staining. Chromosoma 88, 315-318 (1983).
-
(1983)
Chromosoma
, vol.88
, pp. 315-318
-
-
Cornforth, M.N.1
Bedford, J.S.2
-
28
-
-
0021024317
-
X-ray-induced breakage and rejoining of human interphase chromosomes
-
M. N. Cornforth and J. S. Bedford, X-ray-induced breakage and rejoining of human interphase chromosomes. Science 222, 1141-1143 (1983).
-
(1983)
Science
, vol.222
, pp. 1141-1143
-
-
Cornforth, M.N.1
Bedford, J.S.2
-
29
-
-
0026584129
-
Defective repair of radiation-induced chromosomal damage in scid/scid mice
-
J. E. Disney, A. L. Barth and L. D. Shultz, Defective repair of radiation-induced chromosomal damage in scid/scid mice. Cytogenet. Cel. Genet, 59, 39-14 (1992).
-
(1992)
Cytogenet. Cel. Genet
, vol.59
, pp. 39-114
-
-
Disney, J.E.1
Barth, A.L.2
Shultz, L.D.3
-
30
-
-
0027133423
-
Complementation of the radiosensitive phenotype in severe combined immunodeficient mice by human chromosome 8
-
C. U. Kirchgessner, L. M. Tosto, K. A. Biedermann, M. Kovacs, D. Araujo, E. J. Stanbridge and J. M. Brown, Complementation of the radiosensitive phenotype in severe combined immunodeficient mice by human chromosome 8. Cancer Res. 53, 6011-6016 (1993).
-
(1993)
Cancer Res.
, vol.53
, pp. 6011-6016
-
-
Kirchgessner, C.U.1
Tosto, L.M.2
Biedermann, K.A.3
Kovacs, M.4
Araujo, D.5
Stanbridge, E.J.6
Brown, J.M.7
-
31
-
-
0028149198
-
Complementation of V(D)J recombination defect and X-ray sensitivity of scid mouse cells by human chromosome 8
-
S. S. Banga, K. T. Hall, A. K. Sandhu, D. T. Weaver and R. S. Athwal. Complementation of V(D)J recombination defect and X-ray sensitivity of scid mouse cells by human chromosome 8. Mutat. Res. 315, 239-247 (1994).
-
(1994)
Mutat. Res.
, vol.315
, pp. 239-247
-
-
Banga, S.S.1
Hall, K.T.2
Sandhu, A.K.3
Weaver, D.T.4
Athwal, R.S.5
-
32
-
-
0027171959
-
Human chromosome 8 (p12→q22) complements radiosensitivity in the severe combined immune deficiency (SCID) mouse
-
M. Itoh, K. Hamatani, K. Komatsu, R. Araki, K. Takayama and M. Abe. Human chromosome 8 (p12→q22) complements radiosensitivity in the severe combined immune deficiency (SCID) mouse. Radiat. Res. 134, 364-368 (1993).
-
(1993)
Radiat. Res.
, vol.134
, pp. 364-368
-
-
Itoh, M.1
Hamatani, K.2
Komatsu, K.3
Araki, R.4
Takayama, K.5
Abe, M.6
-
33
-
-
0028014320
-
A human gene that restores the DNA-repair defect in SCID mice is located on 8p11.1→q11.1
-
A. Kurimasa, Y. Nagata, M. Shimizu, M. Emi, Y. Nakamura and M. Oshimura, A human gene that restores the DNA-repair defect in SCID mice is located on 8p11.1→q11.1. Hum. Genet. 93, 21-26 (1994).
-
(1994)
Hum. Genet.
, vol.93
, pp. 21-26
-
-
Kurimasa, A.1
Nagata, Y.2
Shimizu, M.3
Emi, M.4
Nakamura, Y.5
Oshimura, M.6
-
34
-
-
0025911213
-
The use of fluorescence in situ hybridisation combined with premature chromosome condensation for the identification of chromosome damage
-
J. W. Evans, J. A. Chang, A. J. Giaccia, D. Pinkel and J. M. Brown, The use of fluorescence in situ hybridisation combined with premature chromosome condensation for the identification of chromosome damage. Br. J. Cancer 63, 517-521 (1991).
-
(1991)
Br. J. Cancer
, vol.63
, pp. 517-521
-
-
Evans, J.W.1
Chang, J.A.2
Giaccia, A.J.3
Pinkel, D.4
Brown, J.M.5
-
35
-
-
0025887647
-
Non-isotopical labeling of murine heterochromatin in situ by hybridization with in vitro-synthesized biotinylated gamma (major) satellite DNA
-
H. U. Weier, H. F. Zitzelsberger and J. W. Gray, Non-isotopical labeling of murine heterochromatin in situ by hybridization with in vitro-synthesized biotinylated gamma (major) satellite DNA. Biotechniques 10, 498-505 (1991).
-
(1991)
Biotechniques
, vol.10
, pp. 498-505
-
-
Weier, H.U.1
Zitzelsberger, H.F.2
Gray, J.W.3
-
36
-
-
0022446922
-
Cytogenetic analysis using quantitative, high-sensitivity, fluorescence hybridization
-
D. Pinkel, T. Straume and J. W. Gray, Cytogenetic analysis using quantitative, high-sensitivity, fluorescence hybridization. Proc. Natl. Acad. Sci. USA 83, 2934-2938 (1986).
-
(1986)
Proc. Natl. Acad. Sci. USA
, vol.83
, pp. 2934-2938
-
-
Pinkel, D.1
Straume, T.2
Gray, J.W.3
-
38
-
-
0028209635
-
Evidence that the product of the xrs gene is predominantly involved in the repair of a subset of radiation-induced interphase chromosome breaks rejoining with fast kinetics
-
R. Okayasu and G. Iliakis, Evidence that the product of the xrs gene is predominantly involved in the repair of a subset of radiation-induced interphase chromosome breaks rejoining with fast kinetics. Radiat. Res. 138, 34-43 (1994).
-
(1994)
Radiat. Res.
, vol.138
, pp. 34-43
-
-
Okayasu, R.1
Iliakis, G.2
-
39
-
-
0027482118
-
Hypertonic treatment during premature chromosome condensation allows visualization of interphase chromosome breaks repaired with fast kinetics in irradiated CHO cells
-
G. Iliakis, R. Okayasu, J. Varlotto, C. Shernoff and Y. Wang, Hypertonic treatment during premature chromosome condensation allows visualization of interphase chromosome breaks repaired with fast kinetics in irradiated CHO cells. Radiat. Res. 135, 160-170 (1993).
-
(1993)
Radiat. Res.
, vol.135
, pp. 160-170
-
-
Iliakis, G.1
Okayasu, R.2
Varlotto, J.3
Shernoff, C.4
Wang, Y.5
-
40
-
-
0028944675
-
Cultured cells from a severe combined immunodeficient mouse have a slower than normal rate of repair of potentially lethal damage sensitive to hypertonic treatment
-
H. Kimura, T. Terado, K. Komatsu, A. Nozawa, M. Ikebuchi and T. Aoyama. Cultured cells from a severe combined immunodeficient mouse have a slower than normal rate of repair of potentially lethal damage sensitive to hypertonic treatment. Radiat. Res. 142, 176-180 (1995).
-
(1995)
Radiat. Res.
, vol.142
, pp. 176-180
-
-
Kimura, H.1
Terado, T.2
Komatsu, K.3
Nozawa, A.4
Ikebuchi, M.5
Aoyama, T.6
|