Intracellular generation of amyloid β-protein from amyloid β-protein precursor fragment by direct cleavage with β-and γ-secretase

Biochemical and Biophysical Research Communications

Volumn 218, Issue 1, 1996, Pages 238-242

  Iizuka, Tomomichi ^a   Shoji, Mikio ^a   Kawarabayashi, Takeshi ^a   Sato, Masahiro ^b   Kobayashi, Takashi ^b   Tada, Norihiro ^b   Kasai, Kazuhiro ^b   Matsubara, Etsuro ^a   Watanabe, Mitsunori ^a   Tomidokoro, Yasushi ^a   Hirai, Shunsaku ^a  

^a GUNMA UNIVERSITY   (Japan)

^b SANOFI   (France)

Author keywords

[No Author keywords available]

Indexed keywords

AMYLOID BETA PROTEIN; AMYLOID PRECURSOR PROTEIN; PROTEINASE;

ALZHEIMER DISEASE; AMINO ACID SUBSTITUTION; AMINO TERMINAL SEQUENCE; ANIMAL CELL; ARTICLE; CARBOXY TERMINAL SEQUENCE; CONTROLLED STUDY; NONHUMAN; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN PROCESSING; PROTEIN SECRETION;

ALZHEIMER DISEASE; AMMONIUM CHLORIDE; AMYLOID BETA-PROTEIN; AMYLOID BETA-PROTEIN PRECURSOR; AMYLOID PRECURSOR PROTEIN SECRETASES; ANIMALS; ASPARTIC ENDOPEPTIDASES; BASE SEQUENCE; CELL LINE; CERCOPITHECUS AETHIOPS; DNA PRIMERS; ENDOPEPTIDASES; HUMANS; KINETICS; LEUPEPTINS; METHYLAMINES; MOLECULAR SEQUENCE DATA; PEPTIDE FRAGMENTS; POLYMERASE CHAIN REACTION; PROTEASE INHIBITORS; PROTEIN PROCESSING, POST-TRANSLATIONAL; RECOMBINANT PROTEINS; TRANSFECTION;

EID: 0030067010     PISSN: 0006291X     EISSN: None     Source Type: Journal    
DOI: 10.1006/bbrc.1996.0042     Document Type: Article

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