Amperometric biosensors

Current Opinion in Biotechnology

Volumn 7, Issue 1, 1996, Pages 50-

  Heller, Adam ^a  

^a The University of Texas at Austin   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AVIDIN; BIOTIN; DNA; GLUCOSE; HYDROGEN PEROXIDE;

AMPEROMETRY; BIOSENSOR; BLOOD GLUCOSE MONITORING; DNA DETERMINATION; IMMUNOASSAY; OXIDATION REDUCTION STATE; PRIORITY JOURNAL; SHORT SURVEY;

EID: 0030066857     PISSN: 09581669     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (39)

1. Bourdillon C, Demaille C, Gueris J, Moiroux J, Saveant JM: A fully active monolayer enzyme electrode derivatized by antigen-antibody attachment. J Am Chem Soc 1993, 115:12264-12269.
2. Bourdillon, C, Demaille C, Moiroux J, Saveant JM: Step-by-step immunological construction of a fully active multilayer enzyme electrode. J Am Chem Soc 1994, 116:10328-10329. This paper reports the construction of an electrode with a known number of enzyme layers. Operation of the multilayer enzyme electrode is analyzed.
3. Vreeke MS, Rocca P: Biosensors based on crosslinking biotinylated glucose oxidase by avidin. Electroanalysis 1996, in press.
4. 2 molecule to the electrode, thereby improving the efficiency of signal transduction.
5. Kulys J, Buch-Rasmussen T, Bechgaard K: Kinetics of glucose oxidase catalyzed electron transfer mediated by sulfur and selenium compounds. FEBS Lett 1993, 329:205-209.
6. Martens N, Hindle A, Hall EAH: An assessment of mediators as oxidants for glucose oxldase in the presence of oxygen. Biosens Bioelectron 1995, 10:393-403.
7. Aoki A, Rajagopalan R, Heller A: Effect of quaternization on electron diffusion coefficients for redox hydrogels based on poly(4vinylpyridine). J Phys Chem 1995, 99:5102-5110. Establishes that electron conduction in redox hydrogels originates from electron-transferring collisions between mobile polymer chain segments. Such knowledge is important to biosensor design.
8. 2 centers of enzymes are efficiently connected to electrodes via redox hydrogels when the enzyme protein and the polymer of the hydrogel are oppositely charged.
9. Talbott J, Jordan J: A new microchemlcal approach to amperometric analysis. Microchem J 1988, 37:5-12.
10. Wang J, Chen O, Pedrero M: Highly selective biosensing of lactate at lactate oxidase containing rhodium-dispersed carbon paste electrodes. Anal Chim Acta 1995, 304:41-46.
11. Wang J, Fang L, Lopez D, Tobias H: Highly selective and sensitive amperometric biosensing of glucose at ruthenium-dispersed carbon paste enzyme electrodes. Anal Lett 1093, 26:1819-1630.
12. Yang L, Janle E, Huang T, Gitzen J, Kissinger PT, Vreeke M, Heller A: Application of 'wired' peroxidase electrodes for peroxide determination in liquid chromatography coupled to oxidase immobilized enzyme reactors. Anal Chem 1995, 67:1326-1331. A horseradish peroxidase electrode, wired using a redox hydrogel, is compared with one with a plain platinum surface. The wired electrode outperforms the platinum electrode because it is not subject to fouling, it has a better detection efficiency and it exhibits an enhanced signal-to-noise ratio.
13. Kennedy RT, Huang L, Atkinson MA, Dush P: Amperometric monitoring of chemical secretions from individual pancreatic beta cells. Anal Chem 1993, 65:1882-1887.
14. 2 with a 'wired' horseradish peroxidase microsensor. J Phys Chem 1995, 99:11896-11900.
15. Horrocks BR, Schmidtke D, Heller A, Bard AJ: SECM 24 enzyme microelectrodes for the measurement of hydrogen peroxide at surfaces. Anal Chem 1993, 65:3605-3614.
16. 2 electroreduction current.
17. Kaneki N, Xu Y, Kumari A, Halsall HB, Heineman WR, Kissinger PT: Electrochemical enzyme immunoassay using sequential saturation technique in a 20 μL capillary digoxin as a model analyts. Anal Chim Acta 1994, 287:253-258. Immunoassays with amperometric detection can be used to determine very small amounts of antigen or antibody in a sample. This report demonstrates an amperometric immunoassay in a 20 μl volume.
18. Jiang T, Halsall HB, Heineman WR, Giersch T, Hock B: Capillary enzyme immunoassay with electrochemical detection for the determination of atrazine in water. J Agric Food Chem 1995, 43:1098-1104. These authors utilize a sandwich immunoassay with amperometric detection to determine atrazine levels in water. The system is capable of detecting an unprecedentedly small number of atrazine molecules in a sample.
19. Rishpon J, Gezundhajt Y, Soussan L, Rosen-Margalit I, Hadas E: Immunoelectrodes for the detection of bacteria. Am Chem Soc Symp Ser 1992, 511:59-72.
20. Duan C, Meyerhoff ME: Separation-free sandwich enzyme immunoassays using microporous gold electrodes and self-assembled monolayer/immobilized capture antibodies. Anal Chem 1994, 66:1369-1377. See annotation for [21•].
21. Duan C, Meyerhoff ME: Immobilization of proteins on gold coated porous membranes via an activated self-assembled monolayer of thioctic acid. Mikrochim Acta 1995, 117:195-206. This paper and [20•] introduce an amperometric immunosensor employing a sandwich immunoassay in a two-compartment cell. The method has the significant advantage of avoiding the need for rinsing.
22. Millan KM, Mikkelsen SR: Sequence-selective biosensor for DNA based on electroactive hybridization indicators. Anal Chem 1993, 65:2317-2323.
23. Millan KM, Saraullo A, Mikkelsen SR: Voltammetric DNA biosensor for cystic fibrosis based on a modified carbon paste electrode. Anal Chem 1994, 66:2943-2948. Voltammetric detection is used to monitor hybridization of a probe to a DNA sequence. In this case, the technique is used to detect a gene associated with disease (i.e. cystic fibrosis).
24. Hashimoto K, Ito K, Ishimori Y: Novel DNA sensor for electrochemical gene detection. Anal Chim Acta 1994, 286:219-224.
25. Diabetes Control and Complications Trial Research Group: The effect of intensive insulin treatment of diabetes on the development and progression of long-term complications in insulin dependent diabetes mellitus. N Engl J Med 1993, 329:977-986.
26. Eastman RC, Siebert CW, Harris M, Gordon P: Clinical review 51. Implications of the diabetes control and complications trial. J Clin Endocrinol Meteb 1993, 77:1105.
27. Moatti-Sirat D, Poitout V, Thome V, Gangnerau MN, Zhang Y, Hu Y, Wilson GS, Lemonnier F, Klein JC, Reach G: Reduction of acetaminophen interference in glucose sensors by a composite Nation membrane: demonstration in rats and man. Diabetologia 1994, 37:610-616. These authors improve the sensitivity of an in vivo glucose sensor through the use of a novel composite membrane. This membrane reduces signal interference by acetaminophen.
28. Bindra DS, Zhang Y, Wilson GS: Design and in vitro studies of a needle-type glucose sensor for subcutaneous monitoring. Anal Chem 1991, 63:1692-1696.
29. Zhang Y, Hu Y, Wilson GS, Moatti-Sirat D, Poitout V, Reach G: Elimination of the acetaminophen interference in an implantable glucose sensor. Anal Chem 1994, 66:1183-1188.
30. Moatti-Sirat D, Capron F, Poitoul V, Reach G, Bindra DS, Zhang Y, Wilson GS, Thévenot DR: Towards continuous glucose monitoring: in vivo evaluation of a miniaturized glucose sensor implanted for several days in rat subcutaneous tissue. Diabetologia 1992, 36:224-230.
31. Poitout V, Moatti-Sirat D, Reach G, Zhang Y, Wilson GS, Lemonnier F, Klein JC: A glucose monitoring system for on line estimation in man of blood glucose concentration using a miniaturized glucose sensor implanted in the subcutaneous tissue and a wearable control unit. Diabetologia 1993, 36:668-663.
32. Moussy F, Jakeway S, Harrison DJ, Rajotte RV: In vitro and in vivo performance and lifetime of perfluorinated ionomer-coated glucose sensors after high-temperature curing. Anal Chem 1994, 66:3882-3888. A glucose-sensing electrode is prepared by curing at a temperature exceeding 100°C. Curing enhances the performance of the perfluorinated ionomer coaled electrode.
33. Moussy F, Harrison DJ, Rajotte RV: A miniaturized Nation-based glucose sensor: in vitro and in vivo evaluation in dogs. Int J Artif Organs 1994, 17:89-94.
34. Moussy F, Harrison DJ: Prevention of the rapid degradation of subcutaneously Implanted Ag/AgCl reference electrodes using polymer coatings. Anal Chem 1994, 66:674-679. These authors show that the Ag/AgCl reference/counter electrode is stabilized by overcoating with Nation™ and high-temperature curing (see also [32•]).
35. Johnson KW, Bryan-Poole N, Mastrototaro JJ: Reduction of electrooxidizable interferent effects: optimization of the applied potential for amperometric glucose sensors. Electroanalysis 1994, 6:321-326.
36. Csöregi EC, Quinn CP, Schmidtke DW, Lindquist S-E, Pishko MV, Ye L, Katakis I, Hubbell A, Heller A: Design, characterization and one-point in vivo calibration of a subcutaneously implanted glucose electrode. Anal Chem 1994, 66:3131-3138. See annotation for [37•].
37. Csöregi E, Schmidtke DW, Heller A: Design and optimization of a selective subcutaneously implantable glucose electrode based on 'wired' glucose oxidase. Anal Chem 1995, 67:1240-1244. This paper and [36•] show that an implanted glucose electrode can be calibrated by assaying a single sample of blood. The electrode is a 0.3 mm plastically deformable microwire.
38. Quinn CP, Pathak CP, Heller A, Hubbell JA: Photo-crosslinked copolymers of 2-hydroxyethyl methacrylate, poly(ethylene glycol) tetra-acrylate and ethylene dimethacrylate for improving biocompatibility of biosensors. Biomaterials 1995, 16:389-396. In this study, sensors are designed with a biocompatible coating that is highly permeable to glucose. The coaling is made by photocrosslinking a tetraacrylated polyethylene oxide.
39. Quinn CP, Pishko MV, Schmidtke DW, Ishikawa M, Wagner JG, Raskin P, Hubbell JA, Heller A: Kinetics of glucose delivery to subcutaneous tissue in rats measured with 0.3 mm amperometric microsensors. Am J Physiol 1995, 269:E155-E161. An amperometric sensor is used to study the kinetics of glucose delivery in rats. For high intravenous doses of glucose, the time delay between glucose concentration maxima in blood and subcutaneous tissue is shown to increase with the size of glucose dose, a phenomenon that results from facilitated transport.