-
1
-
-
0023139907
-
The pulmonary toxicity of talk and granite dust as estimated from an in vivo hamster bioassay
-
Beck, B. B., Feldman, H. A., Brian, J. D., Smith, T. J., Hallock, M., and Gerson, B. (1987). The pulmonary toxicity of talk and granite dust as estimated from an in vivo hamster bioassay. Toxicol. Appl. Pharmacol. 87, 222-234.
-
(1987)
Toxicol. Appl. Pharmacol.
, vol.87
, pp. 222-234
-
-
Beck, B.B.1
Feldman, H.A.2
Brian, J.D.3
Smith, T.J.4
Hallock, M.5
Gerson, B.6
-
2
-
-
0028044669
-
Effects of m-xylene on rat nasal cytochrome P450 mixed function oxidase activities
-
Blanchard, K. T., and Morris, J. B. (1994). Effects of m-xylene on rat nasal cytochrome P450 mixed function oxidase activities. Toxicol. Lett. 70, 253-259.
-
(1994)
Toxicol. Lett.
, vol.70
, pp. 253-259
-
-
Blanchard, K.T.1
Morris, J.B.2
-
3
-
-
0019265962
-
Effects of inducers and inhibitors on drug-metaboliz-ing enzymes and on drug toxicity in extrahepatic tissues
-
Boyd, M. R. (1980a). Effects of inducers and inhibitors on drug-metaboliz-ing enzymes and on drug toxicity in extrahepatic tissues. Exerpta Medica (Environ. Chem., Enzyme Function Human Dis.; Ciba Foundation Symp. 76), 43-66.
-
(1980)
Exerpta Medica Environ. Chem., Enzyme Function Human Dis.; Ciba Foundation Symp.
, vol.76
, pp. 43-66
-
-
Boyd, M.R.1
-
4
-
-
0019046677
-
Biochemical mechanisms in chemical-induced lung injury; Roles of metabolic activation
-
Boyd, M. R. (1980b). Biochemical mechanisms in chemical-induced lung injury; Roles of metabolic activation. CRC Crit. Rev. Toxicol. 17, 103-176.
-
(1980)
CRC Crit. Rev. Toxicol.
, vol.17
, pp. 103-176
-
-
Boyd, M.R.1
-
5
-
-
0018215446
-
In vitro studies on the metabolic activation of the pulmonary toxin, 4-ipomeanol, by rat lung and liver microsomes
-
Boyd, M. R., Burka, L. T., Wilson, B. J., and Sasame, H. A. (1978). In vitro studies on the metabolic activation of the pulmonary toxin, 4-ipomeanol, by rat lung and liver microsomes. J. Pharmacol. Exp. Ther. 207, 677-686.
-
(1978)
J. Pharmacol. Exp. Ther.
, vol.207
, pp. 677-686
-
-
Boyd, M.R.1
Burka, L.T.2
Wilson, B.J.3
Sasame, H.A.4
-
6
-
-
0016333916
-
Ethoxyresorufin: Direct flurimetric assay of a microsomal O-dealkylation which is preferentially inducible by 3-methylcholanthrene
-
Burke, M. D., and Mayer, R. T. (1974). Ethoxyresorufin: Direct flurimetric assay of a microsomal O-dealkylation which is preferentially inducible by 3-methylcholanthrene. Drug Metab. Dispos. 2, 583-588.
-
(1974)
Drug Metab. Dispos.
, vol.2
, pp. 583-588
-
-
Burke, M.D.1
Mayer, R.T.2
-
7
-
-
0022357068
-
Ethoxy-, pentoxy-, and benzyloxyphenoxazones and homologues: A series of substrates to distinguish between different induced cytochromes P-450
-
Burke, M. D., Thompson, S., Elcombe, C. R., Halpert, J., Haaparanta, T., and Mayer, R. T. (1985). Ethoxy-, pentoxy-, and benzyloxyphenoxazones and homologues: A series of substrates to distinguish between different induced cytochromes P-450. Biochem. Pharmacol. 34, 3337-3345.
-
(1985)
Biochem. Pharmacol.
, vol.34
, pp. 3337-3345
-
-
Burke, M.D.1
Thompson, S.2
Elcombe, C.R.3
Halpert, J.4
Haaparanta, T.5
Mayer, R.T.6
-
8
-
-
0024555323
-
Comparative pneumotoxicity of cyclopentadienyl manganese tricarbonyl and methylcyclopentadienyl manganese tricarbonyl
-
Clay, R. J., and Morris, J. B. (1989). Comparative pneumotoxicity of cyclopentadienyl manganese tricarbonyl and methylcyclopentadienyl manganese tricarbonyl. Toxicol. Appl. Pharmacol. 98, 434-443.
-
(1989)
Toxicol. Appl. Pharmacol.
, vol.98
, pp. 434-443
-
-
Clay, R.J.1
Morris, J.B.2
-
9
-
-
0003690992
-
Xenobiotic metabolism by isolated pulmonary bronchiolar and alveolar cells
-
T. E. Gram, Ed., Pergamon Press, New York
-
Devereux, T. R., Domin, B. A., and Philpot, R. M. (1993). Xenobiotic metabolism by isolated pulmonary bronchiolar and alveolar cells. In Metabolic Activation and Toxicity of Chemical Agents to Lung Tissue and Cells (T. E. Gram, Ed.), pp. 25-40. Pergamon Press, New York.
-
(1993)
Metabolic Activation and Toxicity of Chemical Agents to Lung Tissue and Cells
, pp. 25-40
-
-
Devereux, T.R.1
Domin, B.A.2
Philpot, R.M.3
-
10
-
-
0020086178
-
In vitro metabolic activation of the pulmonary toxin, 4-ipomeanol, in nonciliated bronchiolar epithelium (Clara) and alveolar type II cells isolated from rabbit lung
-
Devereux, T. R., Jones, K. G., Bend, J. R., Fouts, J. R., Statham, C. N., and Boyd, M. R. (1982). In vitro metabolic activation of the pulmonary toxin, 4-ipomeanol, in nonciliated bronchiolar epithelium (Clara) and alveolar type II cells isolated from rabbit lung. J. Pharmacol. Exp. Ther. 220, 223-227.
-
(1982)
J. Pharmacol. Exp. Ther.
, vol.220
, pp. 223-227
-
-
Devereux, T.R.1
Jones, K.G.2
Bend, J.R.3
Fouts, J.R.4
Statham, C.N.5
Boyd, M.R.6
-
11
-
-
0022527271
-
An improved method for isolating type II cells in high yield and purity
-
Dobbs, L. G., Gonzalez, R., and Williams, M. C. (1986). An improved method for isolating type II cells in high yield and purity. Am. Rev. Respir. Dis. 134, 141-145.
-
(1986)
Am. Rev. Respir. Dis.
, vol.134
, pp. 141-145
-
-
Dobbs, L.G.1
Gonzalez, R.2
Williams, M.C.3
-
12
-
-
0022475744
-
The cytochrome P-450 monooxygenase system of rabbit lung: Enzyme components, activities, and induction in the nonciliated bronchiolar epithelial (Clara) cell, alveolar type II cell and alveolar macrophage
-
Domin, B. A., Devereux, T. R., and Philpot, R. M. (1986). The cytochrome P-450 monooxygenase system of rabbit lung: Enzyme components, activities, and induction in the nonciliated bronchiolar epithelial (Clara) cell, alveolar type II cell and alveolar macrophage. Mol. Pharmacol. 30, 296-303.
-
(1986)
Mol. Pharmacol.
, vol.30
, pp. 296-303
-
-
Domin, B.A.1
Devereux, T.R.2
Philpot, R.M.3
-
13
-
-
0343255244
-
-
Federal Register (1993). Vol. 58, No. 235.
-
(1993)
Federal Register
, vol.58
, Issue.235
-
-
-
14
-
-
0019973340
-
Pulmonary toxicity of methylcyclopentadienyl manganese tricarbonyl: Nonciliated bronchiolar epithelial (Clara) cell necrosis and alveolar damage in the mouse, rat, and hamster
-
Hakkinen, P. J., and Haschek, W. M. (1982). Pulmonary toxicity of methylcyclopentadienyl manganese tricarbonyl: Nonciliated bronchiolar epithelial (Clara) cell necrosis and alveolar damage in the mouse, rat, and hamster. Toxicol. Appl. Pharmacol. 65, 11-22.
-
(1982)
Toxicol. Appl. Pharmacol.
, vol.65
, pp. 11-22
-
-
Hakkinen, P.J.1
Haschek, W.M.2
-
15
-
-
0019139164
-
Toxic effects of methylcyclopentadienyl manganese tricarbonyl (MMT) in rats: Role of metabolism
-
Hanzlik, R. P., Stitt, R., and Traiger, G. J. (1980). Toxic effects of methylcyclopentadienyl manganese tricarbonyl (MMT) in rats: Role of metabolism. Toxicol. Appl. Pharmacol. 56, 353-360.
-
(1980)
Toxicol. Appl. Pharmacol.
, vol.56
, pp. 353-360
-
-
Hanzlik, R.P.1
Stitt, R.2
Traiger, G.J.3
-
16
-
-
0025053596
-
Hepatocidal toxicity of Listeria species
-
Huang, J. C., Huang, H. S., Jurima-Romet, M., Ashton, F., and Thomas, B. H. (1990). Hepatocidal toxicity of Listeria species. FEMS Microbiol. Lett. 72, 249-252.
-
(1990)
FEMS Microbiol. Lett.
, vol.72
, pp. 249-252
-
-
Huang, J.C.1
Huang, H.S.2
Jurima-Romet, M.3
Ashton, F.4
Thomas, B.H.5
-
17
-
-
0342723384
-
Hepatic nonaltruism and pulmonary toxicity of pyrrolizidine alkaloids
-
T. E. Gram, Ed., Pergamon Press, New York
-
Huxtable, R. J. (1993). Hepatic nonaltruism and pulmonary toxicity of pyrrolizidine alkaloids. In Metabolic Activation and Toxicity of Chemical Agents to Lung Tissue and Cells (T. E. Gram, Ed.), pp. 213-232. Pergamon Press, New York.
-
(1993)
Metabolic Activation and Toxicity of Chemical Agents to Lung Tissue and Cells
, pp. 213-232
-
-
Huxtable, R.J.1
-
18
-
-
0020528192
-
Xenobiotic metabolism in Clara cells and alveolar type II cells isolated from rats treated with b-naphthoflavone
-
Jones, K. G., Holland, J. F., Foureman, G. L., Bend, J. R., and Fouts, J. R. (1983). Xenobiotic metabolism in Clara cells and alveolar type II cells isolated from rats treated with b-naphthoflavone. J. Pharmacol. Exp. Ther. 225, 316-319.
-
(1983)
J. Pharmacol. Exp. Ther.
, vol.225
, pp. 316-319
-
-
Jones, K.G.1
Holland, J.F.2
Foureman, G.L.3
Bend, J.R.4
Fouts, J.R.5
-
19
-
-
0021873353
-
Systemically applied chemicals that damage lung tissue
-
Kehren, J. P., and Kacew, S. (1985). Systemically applied chemicals that damage lung tissue. Toxicology 35, 251-293.
-
(1985)
Toxicology
, vol.35
, pp. 251-293
-
-
Kehren, J.P.1
Kacew, S.2
-
20
-
-
0023115083
-
Immunological identification and effects of 3-methylcholanthrene and phenobarbital on rat pulmonary cytochrome P-450
-
Keith, I. M., Olson, E. B., Jr., Wilson, N. M., and Jefcoate, C. R. (1987). Immunological identification and effects of 3-methylcholanthrene and phenobarbital on rat pulmonary cytochrome P-450. Cancer Res. 47, 1878-1882.
-
(1987)
Cancer Res.
, vol.47
, pp. 1878-1882
-
-
Keith, I.M.1
Olson E.B., Jr.2
Wilson, N.M.3
Jefcoate, C.R.4
-
21
-
-
0003122802
-
Preparation and characterization of microsomal fractions for studies on xenobiotic metabolism
-
K. Snell and B. Mullock, Eds., IRL Press, Washington, DC
-
Lake, B. G. (1987). Preparation and characterization of microsomal fractions for studies on xenobiotic metabolism. In Biochemical Toxicology: A Practical Approach (K. Snell and B. Mullock, Eds.), pp. 183-214. IRL Press, Washington, DC.
-
(1987)
Biochemical Toxicology: A Practical Approach
, pp. 183-214
-
-
Lake, B.G.1
-
22
-
-
71849104860
-
Protein measurement with folin phenol reagent
-
Lowry, O. H., Rosenbrough, N. J., Farr, A. L., and Randall, R. J. (1951). Protein measurement with folin phenol reagent. J. Biol. Chem. 193, 265-275.
-
(1951)
J. Biol. Chem.
, vol.193
, pp. 265-275
-
-
Lowry, O.H.1
Rosenbrough, N.J.2
Farr, A.L.3
Randall, R.J.4
-
23
-
-
0025172008
-
Bioactivation of 3-methylindole by isolated rabbit lung cells
-
Nichols, W. K., Larson, D. N., and Yost, G. S. (1990). Bioactivation of 3-methylindole by isolated rabbit lung cells. Toxicol. Appl. Pharmacol. 105, 264-270.
-
(1990)
Toxicol. Appl. Pharmacol.
, vol.105
, pp. 264-270
-
-
Nichols, W.K.1
Larson, D.N.2
Yost, G.S.3
-
24
-
-
0026544554
-
Cellular localization of flavin-containing monooxygenase in rabbit lung
-
Overby, L., Nishio, S. J., Lawton, M. P., Plopper, C. G., and Philpot, R. M. (1992). Cellular localization of flavin-containing monooxygenase in rabbit lung. Exp. Lung Res. 18, 131-144.
-
(1992)
Exp. Lung Res.
, vol.18
, pp. 131-144
-
-
Overby, L.1
Nishio, S.J.2
Lawton, M.P.3
Plopper, C.G.4
Philpot, R.M.5
-
25
-
-
0021966653
-
The acute toxicity of cyclopentadienyl manganese tricarbonyl in the rat
-
Penney, D. A., Hogberg, K., Traiger, G. J., and Hanzlik, R. P. (1985). The acute toxicity of cyclopentadienyl manganese tricarbonyl in the rat. Toxicology 34, 341-347.
-
(1985)
Toxicology
, vol.34
, pp. 341-347
-
-
Penney, D.A.1
Hogberg, K.2
Traiger, G.J.3
Hanzlik, R.P.4
-
26
-
-
0025321401
-
Lung cytochrome P450-dependent benzyloxyphenoxazone debenzylase and ethoxyphenoxazone deethylase activities in total microsomal and isolated alveolar type II cells: Responses to changes in assay conditions with special reference to non-linear dependence at low enzyme concentrations
-
Rabovsky, J., Goddard, J. M., Pailes, W. H., and Castranova, V. (1990). Lung cytochrome P450-dependent benzyloxyphenoxazone debenzylase and ethoxyphenoxazone deethylase activities in total microsomal and isolated alveolar type II cells: Responses to changes in assay conditions with special reference to non-linear dependence at low enzyme concentrations. Int. J. Biochem. 22, 171-177.
-
(1990)
Int. J. Biochem.
, vol.22
, pp. 171-177
-
-
Rabovsky, J.1
Goddard, J.M.2
Pailes, W.H.3
Castranova, V.4
-
27
-
-
0023582096
-
Cytochrome P450-dependent alkoxyphenoxazone dealkylase activities in lung microsomes from untreated and b-naphthoflavone-treated rats: Effect of in vitro inhibitors
-
Rabovsky, J., and Judy, D. J. (1987). Cytochrome P450-dependent alkoxyphenoxazone dealkylase activities in lung microsomes from untreated and b-naphthoflavone-treated rats: Effect of in vitro inhibitors. Res. Commun. Chem. Pathol. Pharmacol. 57(3), 375-387.
-
(1987)
Res. Commun. Chem. Pathol. Pharmacol.
, vol.57
, Issue.3
, pp. 375-387
-
-
Rabovsky, J.1
Judy, D.J.2
-
28
-
-
0025843701
-
Dealkylation of 7-methoxycoumarin as an assay for measuring constitutive and phenobarbital-inducible cytochrome P450s
-
Reen, R. K., Ramakanth, S., Weible, F. J., Jain, M. P., and Singh, J. (1991). Dealkylation of 7-methoxycoumarin as an assay for measuring constitutive and phenobarbital-inducible cytochrome P450s. Anal. Biochem. 194(2), 243-249.
-
(1991)
Anal. Biochem.
, vol.194
, Issue.2
, pp. 243-249
-
-
Reen, R.K.1
Ramakanth, S.2
Weible, F.J.3
Jain, M.P.4
Singh, J.5
-
29
-
-
6844253381
-
Metabolism of endogenous and xenobiotic substances by pulmonary vascular endothelial cells
-
T. E. Gram, Ed., Pergamon Press, New York
-
Ryan, U. S., and Li, A. P. (1993). Metabolism of endogenous and xenobiotic substances by pulmonary vascular endothelial cells. In Metabolic Activation and Toxicity of Chemical Agents to Lung Tissue and Cells (T. E. Gram, Ed.), pp. 107-122. Pergamon Press, New York.
-
(1993)
Metabolic Activation and Toxicity of Chemical Agents to Lung Tissue and Cells
, pp. 107-122
-
-
Ryan, U.S.1
Li, A.P.2
-
30
-
-
0023889046
-
The distribution of cytochrome P-450 monooxygenase in cells of the rabbit lung: An ultrastructural immunocytochemical characterization
-
Serabjit-Singh, C. J., Nishio, S. J., Philpot, R. M., and Plopper, C. G. (1988). The distribution of cytochrome P-450 monooxygenase in cells of the rabbit lung: An ultrastructural immunocytochemical characterization. Mol. Pharmacol. 33, 279-289.
-
(1988)
Mol. Pharmacol.
, vol.33
, pp. 279-289
-
-
Serabjit-Singh, C.J.1
Nishio, S.J.2
Philpot, R.M.3
Plopper, C.G.4
-
32
-
-
0343255233
-
Toxicology of methylcyclopentadienyl manganese tricarbonyl (MMT) and related manganese compounds emitted from mobile and stationary sources
-
Report AMRL-TR-73-125, Paper 20
-
Stara, J., Moore, W., Hysell, D., Lee, S., Lewkowski, J., Hall, L., Campbell, K., and Wiester, M. (1973). Toxicology of methylcyclopentadienyl manganese tricarbonyl (MMT) and related manganese compounds emitted from mobile and stationary sources. Proc. 4th Ann. Conf. Environ. Toxicol. (Report AMRL-TR-73-125, Paper 20), 251-270.
-
(1973)
Proc. 4th Ann. Conf. Environ. Toxicol.
, pp. 251-270
-
-
Stara, J.1
Moore, W.2
Hysell, D.3
Lee, S.4
Lewkowski, J.5
Hall, L.6
Campbell, K.7
Wiester, M.8
-
33
-
-
0027381510
-
Cytochrome P450 2B isozymes are responsible for the pulmonary bioactivation and toxicity of butylated hydroxytoluene, O,O,S-trimethylphosphorothioate and methylcyclopentadienyl manganese tricarbonyl
-
Verschoyle, R. D., Wolf, C. R., and Dinsdale, D. (1993). Cytochrome P450 2B isozymes are responsible for the pulmonary bioactivation and toxicity of butylated hydroxytoluene, O,O,S-trimethylphosphorothioate and methylcyclopentadienyl manganese tricarbonyl. J. Pharmacol. Exp. Ther. 266(2), 958-963.
-
(1993)
J. Pharmacol. Exp. Ther.
, vol.266
, Issue.2
, pp. 958-963
-
-
Verschoyle, R.D.1
Wolf, C.R.2
Dinsdale, D.3
-
34
-
-
0025037874
-
In situ localization and distribution of xenobiotic-activating enzymes and aryl hydrocarbon hydrolase activity in lungs of untreated rats
-
Voigt, J. M., Kawabata, T. T., Burke, J. P., Martin, M. V., Guengerich, F. P., and Baron, J. (1990). In situ localization and distribution of xenobiotic-activating enzymes and aryl hydrocarbon hydrolase activity in lungs of untreated rats. Mol. Pharmacol. 37, 182-191.
-
(1990)
Mol. Pharmacol.
, vol.37
, pp. 182-191
-
-
Voigt, J.M.1
Kawabata, T.T.2
Burke, J.P.3
Martin, M.V.4
Guengerich, F.P.5
Baron, J.6
-
35
-
-
0011905566
-
Lactate dehydrogenase: uv method with L-lactate and NAD
-
H. U. Bergmeyer, Ed., 3rd ed., Academic Press, New York
-
Wahlefeld, A. W. (1985). Lactate dehydrogenase: uv method with L-lactate and NAD. In Methods of Enzymatic Analysis (H. U. Bergmeyer, Ed.), 3rd ed., Vol. 2, pp. 574-579. Academic Press, New York.
-
(1985)
Methods of Enzymatic Analysis
, vol.2
, pp. 574-579
-
-
Wahlefeld, A.W.1
-
36
-
-
0016566218
-
A physiological approach to hepatic drug clearance
-
Wilkinson, G. R., and Shand, D. G. (1975). A physiological approach to hepatic drug clearance. Clin. Pharmacol. Ther. 18(4), 377-389.
-
(1975)
Clin. Pharmacol. Ther.
, vol.18
, Issue.4
, pp. 377-389
-
-
Wilkinson, G.R.1
Shand, D.G.2
-
37
-
-
0024416367
-
Mechanisms of 3-methylindole pneumotoxicity
-
Yost, G. S. (1989). Mechanisms of 3-methylindole pneumotoxicity. Chem. Res. Toxicol. 2(5), 273-279.
-
(1989)
Chem. Res. Toxicol.
, vol.2
, Issue.5
, pp. 273-279
-
-
Yost, G.S.1
-
38
-
-
0024762304
-
Contemporary issues in toxicology: Mechanisms of lung injury by systemically administered chemicals
-
Yost, G. S., Buckpitt, A. R., Roth, R. A., and McLemore, T. L. (1989). Contemporary issues in toxicology: Mechanisms of lung injury by systemically administered chemicals. Toxicol. Appl. Pharmacol. 101, 179-195.
-
(1989)
Toxicol. Appl. Pharmacol.
, vol.101
, pp. 179-195
-
-
Yost, G.S.1
Buckpitt, A.R.2
Roth, R.A.3
McLemore, T.L.4
|