Synthesis, enzymatic phosphorylation and antiviral activity of acyclic dienyl phosphonate derivatives of guanine

Bioorganic and Medicinal Chemistry Letters

Volumn 6, Issue 2, 1996, Pages 179-184

  Navé, Jean François ^a   Casara, Patrick J ^a   Taylor, Debra L ^b   Tyms, A Stanley ^b   Kenny, Michael ^c   Halazy, Serge ^a,d  

^a SANOFI   (France)

^b MEDICAL RESEARCH COUNCIL   (United Kingdom)

^c Marion Merrell Dow Inc   (United States)

^d INSTITUT DE RECHERCHE PIERRE FABRE   (France)

Author keywords

[No Author keywords available]

Indexed keywords

9 (5 PHOSPHONO 3 METHYLENE 4 PENTENYL)GUANINE; 9 [2 (PHOSPHONOMETHOXY)ETHYL]ADENINE; ANTIVIRUS AGENT; DIDANOSINE; GUANINE DERIVATIVE; GUANYLATE KINASE; UNCLASSIFIED DRUG; ZIDOVUDINE;

ANIMAL CELL; ANTIVIRAL ACTIVITY; ARTICLE; CONTROLLED STUDY; CYTOMEGALOVIRUS; CYTOTOXICITY; DRUG SYNTHESIS; ENZYME ACTIVITY; HERPES SIMPLEX VIRUS 1; HUMAN; HUMAN CELL; HUMAN IMMUNODEFICIENCY VIRUS 1; NONHUMAN; NUCLEAR MAGNETIC RESONANCE; PHOSPHORYLATION;

EID: 0030066729     PISSN: 0960894X     EISSN: None     Source Type: Journal    
DOI: 10.1016/0960-894X(95)00585-H     Document Type: Article

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