Corticosterone modulates behavioral and metabolic effects of lipopolysaccharide

American Journal of Physiology - Regulatory Integrative and Comparative Physiology

Volumn 270, Issue 1 39-1, 1996, Pages

  Johnson, R W ^a   Propes, M J ^b   Shavit, Y ^b  

^a UNIVERSITY OF ILLINOIS AT URBANA CHAMPAIGN   (United States)

^b NONE

Author keywords

cytokines; endotoxin; glucocorticoids; metabolism; rat

Indexed keywords

CORTICOSTERONE; CYTOKINE; ESCHERICHIA COLI LIPOPOLYSACCHARIDE; GLUCOCORTICOID; PLACEBO;

ADRENALECTOMY; ANIMAL BEHAVIOR; ANIMAL EXPERIMENT; ARTICLE; BODY TEMPERATURE; CONTROLLED STUDY; CORTICOSTERONE BLOOD LEVEL; EXPERIMENTAL INFECTION; HORMONAL REGULATION; HYPOTHALAMUS HYPOPHYSIS ADRENAL SYSTEM; ILLNESS BEHAVIOR; MALE; METABOLISM; NEUROIMMUNOLOGY; NONHUMAN; PRIORITY JOURNAL; RADIOIMMUNOASSAY; RAT; SOCIAL BEHAVIOR; WEIGHT GAIN;

EID: 0030066646     PISSN: 03636119     EISSN: None     Source Type: Journal    
DOI: 10.1152/ajpregu.1996.270.1.r192     Document Type: Article

References (28)

1. Ban, E., C. Marquette, A. Sarrieau, F. Fitzpatrick, G. Fillion, G. Milon, W. Rostene, and F. Haour. Regulation of interleukin-1 receptor expression in mouse brain and pituitary by lipopolysaccharide and glucocorticoids. Neuroendocrinology 58: 581-587, 1993.
2. Berkenbosch, F., J. van Oers, A. del Rey, F. Tilders, and H. Besedovsky. Corticotropin-releasing factor-producing neurons in the rat activated by interleukin-1. Science Wash. DC 238: 524-526, 1987.
3. Bertini, R., M. Bianchi, and P. Ghezzi. Adrenalectomy sensitizes mice to the lethal effects of interleukin 1 and tumor necrosis factor. J. Exp. Med. 167: 1708-1712, 1988.
4. Betancur, C., A. Lledó, J. Borrell, and C. Guaza. Corticosteroid regulation of IL-1 receptors in the mouse hippocampus: effects of glucocorticoid treatment, stress, and adrenalectomy. Neuroendocrinology 59: 120-128, 1994.
5. Blalock, J. E. The immune system: our sixth sense. The Immunologist 2: 8-15, 1994.
6. Bluthé, R.-M., R. Dantzer, and K. W. Kelley. Interleukin-1 mediates behavioural but not metabolic effects of tumor necrosis factor a in mice. Eur. J. Pharmacol. 209: 281-283, 1991.
7. Bluthé, R.-M., R. Dantzer, K. W. Kelley. Effects of interleukin-1 receptor antagonist on the behavioral effects of lipopolysaccharide in rat. Brain Res. 573: 318-320, 1992.
8. Bluthé, R.-M., P. Parnet, R. Dantzer, and K. W. Kelley. Interleukin-1 receptor antagonist blocks effects of IL-1α on social behaviour and body weight in mice. Neurosci. Res. Commun. 15: 151-158, 1991.
9. Bluthé, R.-M., M. Pawlowski, S. Suarez, P. Parnet, Q. Pittman, K. W. Kelley, and R. Dantzer. Synergy between tumor necrosis factor α and interleukin-1 in the induction of sickness behavior in mice. Psychoneuroendocrinology 19: 197-207, 1994.
10. Chover-Gonzalez, A. J., M. S. Harbuz, and S. L. Lightman. Effect of adrenalectomy and stress on interleukin-1β-mediated activation of hypothalamic corticotropin-releasing factor mRNA. J. Neuroimmunol. 42: 155-160, 1993.
11. Coelho, M. M., G. E. P. Souza, and I. R. Pela. Endotoxin-induced fever is modulated by endogenous glucocorticoids in rats. Am. J. Physiol. 263 (Regulatory Integrative Comp. Physiol. 32): R423-R427, 1992.
12. Dinarello, C. A. Biology of interleukin 1. FASEB J. 2: 108-115, 1988.
13. Dunhara, D. M., S. Arkins, C. K. Edwards, III, R. Dantzer, and K. W. Kelley. Role of interferon-γ in counteracting the suppressive effects of transforming growth factor-β2 and glucocorticoids on the production of tumor necrosis factor-α. J. Leukocyte Biol. 48: 473-481, 1990.
14. Hart, B. L. Biological basis of the behavior of sick animals. Neurosci. Biobehav Rev. 12: 123-137, 1988.
15. Johnson, R. W., and E. von Borell. Lipopolysaceharide-induced sickness behavior in pigs is inhibited by pretreatment with indomethacin. J. Anim. Sci. 72: 809-314, 1994.
16. Kakucska, I., Y. Qi, B. D. Clark, and R. M. Lechan. Endotoxin-induced corticotropin-releasing hormone gene expression in the hypothalamic paraventricular nucleus is mediated centrally by interleukin-1. Endocrinology 133: 815-821, 1993.
17. Kent, S., R.-M. Bluthé, R. Dantzer, A. J. Hardwick, K. W. Kelley, N. J. Rothwell, and J. L. Vannice. Different receptor mechanisms mediate the pyrogenic and behavioral effects of interleukin 1. Proc. Natl. Acad. Sci. USA 89: 9117-9120, 1992.
18. Kluger, M. J. Fever: role of pyrogens and cryogens. Physiol. Rev. 71: 93-127, 1991.
19. Knudsen, P. J., C. A. Dinarello, and T. B. Strom. Glucocorticoids inhibit transcriptional and post-transcriptional expression of interleukin 1 in U937 cells. J. Immunol. 139: 4129-4134, 1987.
20. Lee, S. W., A.-P. Tsou, H. Chan, J. Thomas, K. Petrie, E. M. Eugui, and A. C. Allison. Glucocorticoids selectively inhibit the transcription of the interleukin 1β gene and decrease the stability of interleukin 1β mRNA. Proc. Natl. Acad. Sci. USA 85: 1204-1208, 1988.
21. McCallum, R. E., S. S. Lloyd, and S. R. Hyde. Enhanced TNF response in endotoxic mice after treatment with the glucocorticoid antagonist RU 486. In: Cellular and Molecular Aspects of Endotoxin Reactions, edited by A. Nowotny, J. J. Spitzer, and E. J. Ziegler. New York: Elsevier, 1990, p. 493-500.
22. Morrow, L. E., J. L. McClellan, C. A. Conn, and M. J. Kluger. Glucocorticoids alter fever and IL-6 responses to psychological stress and to lipopolysaccharide. Am. J. Physiol. 264 (Regulatory Integrative Comp. Physiol. 33):R1010-R1016, 1993.
23. Perlstein, R. S., M. H. Whitnall, J. S. Abrams, E. H. Mougey, and R. Neta. Synergistic roles of interleukin-6, interleukin-1, and tumor necrosis factor in the adrenocorticotropin response to bacterial lipopolysaccharide in vivo. Endocrinology 132: 946-952, 1993.
24. Plata-Salamán, C. R., Y. Oomura, and Y. Kai. Tumor necrosis factor and interleukin-1β: suppression of food intake by direct action in the central nervous system. Brain Res. 448: 106-114, 1988.
25. Sapolsky, R., C. Rivier, G. Yamamoto, P. Plotsky, and W. Vale. Interleukin-1 stimulates the secretion of hypothalamic corticotropin-releasing factor. Science Wash. DC 238: 522-524, 1987.
26. SAS Institute, Inc. SAS/STAT User's Guide, (4th ed.). Cary, NC: SAS Institute, Version 6, 1992.
27. Staruch, M. J., and D. D. Wood. Reduction of serum interleukin-1-like activity after treatment with dexamethasone. J. Leukocyte Biol. 37: 193-207, 1985.
28. Zuckerman, S. H., J. Shellhaas, and L. D. Butler. Differential regulation of lipopolysaccharide-induced interleukin 1 and tumor necrosis factor synthesis: effects of endogenous and exogenous glucocorticoids and the role of the pituitary-adrenal axis. Eur. J. Immunol. 19: 301-305, 1989.