Ischemia - A coagulation problem?

Journal of Cardiovascular Pharmacology

Volumn 27, Issue SUPPL. 1, 1996, Pages

  Spiess, Bruce D ^a  

^a UNIVERSITY OF WASHINGTON   (United States)

Author keywords

Cardiopulmonary bypass; Coagulation; Hematocrit; Inflammation; Myocardial ischemia; Plasminogen activator inhibitor

Indexed keywords

PLASMINOGEN ACTIVATOR INHIBITOR; PROTAMINE; TISSUE PLASMINOGEN ACTIVATOR;

BLOOD CLOTTING; CONFERENCE PAPER; CORONARY ARTERY BYPASS GRAFT; ENDOTHELIUM CELL; FIBRIN CLOT; FIBRINOLYSIS; HEART INFARCTION; HEMATOCRIT; HUMAN; INFLAMMATION; ISCHEMIA; PEROPERATIVE COMPLICATION; PLASMINOGEN ACTIVATION; PRIORITY JOURNAL; THROMBOCYTE AGGREGATION;

EID: 0030066474     PISSN: 01602446     EISSN: None     Source Type: Journal    
DOI: 10.1097/00005344-199600001-00009     Document Type: Conference Paper

References (19)

1. Jain U. Myocardial infarction during coronary artery bypass surgery. J Cardiothorac Vasc Anesth 1992;6:612-23.
2. Mangano DT. Perioperative cardiac morbidity. Anesthesiology 1990;72:153-84.
3. Thompson SG, Kiemast J, Pyke SDM, et al. Hemostatic factors and the risk of myocardial infarction or sudden death in patients with angina pectoris. N Engl J Med 1995;332:635-41.
4. ECAT Angina Pectoris Study. Baseline associations of haemostatic factors with extent of coronary arteriosclerosis and other coronary risk factors in 3000 patients with angina pectoris undergoing coronary angiography. Eur Heart J 1993;14:8-17.
5. Kostis JB, Baughman DJ, Kuo PT. Association of recurrent myocardial infarction with hemostatic factors: a prospective study. Chest 1982;81:571-5.
6. Smith RC, Leung JM, Mangano DT. Postoperative myocardial ischemia in patients undergoing coronary artery bypass graft surgery. S.P.I. Research Group. Anesthesiology 1991;74:464-73.
7. Jain U, Wallis De, Moran JF. Significance of electrocardiographic ST elevation during coronary artery bypass surgery. Anesth Analg 1994;78:638-43.
8. Selke FW, Shafique T, Ely DL, et al. Coronary endothelial injury after cardiopulmonary bypass and ischemic cardioplegia is mediated by oxygen-derived free radicals. Circulation 1993;88: 395-400.
9. Rinder CS, Bonan JL, Mathew J, Hines R, Smith BR. Cardiopulmonary bypass induces leukocyte-platelet adhesion. Blood 1992;79:1201-5.
10. Wilson I, Gillinov AM, Curtis WE, et al. Inhibition of neutrophil adherence improves postischemic ventricular performance of the neonatal heart. Circulation 1993;88:II372-9.
11. Hashimoto K, Pearson PJ, Schaff HV, Cartier R. Endothelial cell dysfunction after ischemic arrest and reperfusion: a possible mechanism of myocardial injury during reflow. J Thorac Cardiovasc Surg 1991;102:688-94.
12. Mollace V, Salvemini D, Sessa WC, Vane JR. Inhibition of human platelet aggregation by endothelium-derived relaxing factor, sodium nitroprusside or iloprost is potentiated by captopril and reduced thiols. J Pharmacol Exp Ther 1991;258:820-3.
13. Kawata H, Aoki M, Mayer J Jr. Nitroglycerin improves functional recovery of neonatal lamb hearts after 2 hours of cold ischemia. Circulation 1993;88:11366-71.
14. Evora PR, Pearson PJ, Schaff HV. Crystalloid cardioplegia and hypothermia do not impair endothelium-dependent relaxation or damage vascular smooth muscle of epicardial coronary arteries. J Thorac Cardiovasc Surg 1992;104:1365-74.
15. Mankad PS, Chester AH, Yacoub MH. Role of potassium concentration in cardioplegic solutions in mediating endothelial damage. Ann Thorac Surg 1991;51:89-93.
16. Tanaka K, Takao M, Yada I, Yuasa H, Kusagawa M, Deguchi K. Alterations in coagulation and fibrinolysis associated with cardiopulmonary bypass during open heart surgery. J Cardiothorac Anesth 1989;3:181-8.
17. Gouin I, Lecompte T, Morel MC, et al. In vitro effect of plasmin on human platelet function in plasma. Inhibition of aggregation caused by fibrinogenolysis. Circulation 1992;85:935-41.
18. Chandler WL, Fitch JCK, Wall MH, et al. Individual variations in the fibrinolytic response during and after cardiopulmonary bypass. J Thromb Haemost [submitted].
19. Spiess BD, Kapitan S, Body S, et al. ICU entry hematocrit does influence the risk for perioperative myocardial infarction (MI) in coronary artery bypass graft surgery [Abstract]. Anesth Analg 1995;80:SCA47.