Virus-induced autoimmune disease: Transgenic approach to mimic insulin-dependent diabetes mellitus and multiple sclerosis

Current Topics in Microbiology and Immunology

Volumn 206, Issue , 1996, Pages 67-83

  Oldstone, M B A ^a   Von Herrath, M ^a   Evans, C F ^a   Horwitz, M S ^a  

^a SCRIPPS RESEARCH INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANIMAL MODEL; CELL INFILTRATION; INSULIN DEPENDENT DIABETES MELLITUS; LYMPHOCYTIC CHORIOMENINGITIS VIRUS; MAJOR HISTOCOMPATIBILITY COMPLEX; MOUSE; MULTIPLE SCLEROSIS; NONHUMAN; PRIORITY JOURNAL; REVIEW; THYMUS; TRANSGENIC MOUSE; VIRUS INFECTION;

ANIMALIA; CHORIOMENINGITIS VIRUS; LYMPHOCYTIC CHORIOMENINGITIS VIRUS; MUS MUSCULUS;

EID: 0030066265     PISSN: 0070217X     EISSN: None     Source Type: Book Series    
DOI: 10.1007/978-3-642-85208-4_5     Document Type: Review

References (34)

1. Allison J, Campbell I, Morahau G, Mandil E, Harrison C, Miller JFAP (1988) IDDM in transgenic mice resulting from over-expression of class I molecules in pancreatic β-cells. Nature 333: 529-533
2. Chisari F, Filippi P, Burns J, McLachlan A, Popper H, Pinkert C, Palmiter P, Brinster R (1987) Structural and pathological effects of synthesis of hepatitis B virus large envelope polypeptide in transgenic mice. Proc Natl Acad Sci USA 84: 6909-6913
3. Chisari F, Klopchin K, Moriyama T, Pasquinelli C, Dunsford H, Sell S, Pinkert C (1989) Molecular pathogenesis of hepatocetlular carcinoma in hepatitis B virus transgenic mice. Cell 58: 1145-1156
4. Ebers GC, Bulman DE, Sadovnick AD, Paty DW, Warren S, Hader W, Murray TJ, Seleand TP, Duquette P, Grey T et al. (1986) A population-based study of multiple sclerosis in twins. N Engl J Med 315. 1638-1642
5. Gow A, Friedrich VL Jr, Lazzarini RA (1992) Myelin basic protein gene contains separate enhancers for oligodendrocyte and Schwann cell expression. J Cell Biol 119. 605-616
6. Green A (1990) The role of genetic factors in development of insulin dependent diabetes mellitus. Curr Top Microbiol Immunol 164: 3-17
7. Horie H, Koike S, Kurata T, Sato-Yoshida Y et al. (1994) Transgenic mice carrying the human poliovirus receptor: new animal model for study of poliovirus neurovirulence. J Virol 68: 681-688
8. Horwitz MS, Evans CF, Lazzarini RA, Oldstone MBA (1994) A transgenic model for immune mediated demyelination. FASEB J 8. 1142
9. Koike A, Taya C, Kurata T, Abe S et al. (1991) Transgenic mice susceptible to poliovirus. Proc Natl Acad Sci USA 88: 951-955
10. Kotzin BL (1993) Twins and T-cell responses. 364: 187-188
11. La Porte RE, Tajima N, Akerblom HK, Berlin MD, Brosseau J, Chrisley M, Drash AI, Fishbein H, Green A, Hamman R, Harris M, King H, Zaron Z, Neil A (1985) Geographic difference in the risk of IDDM. the importance of registries. Diabetes Care 8 Suppl: 101-107
12. Lo D, Burkly L, Widera G, Cowing L, Flavell RA, Palmiter R, Brinster R (1988) Diabetes and tolerance in transgenic mice expression class II MHC molecules in pancreatic β-cells. Cell 53: 159-168
13. Marks J, Lin J, Hinds P, Miller D, Levine A (1989) Cellular gene expression in papilloma of the choroid plexus from transgenic mice that express the simian 40 large T antigen J Virol 63: 790-797
14. Michelsen B, Dyberg T, Visssing H, Serup P, Lermark A (1990) HLA-DQ and -DX genes in IDDM. Curr Top Microbiol Immunol 164. 57-70
15. Nerenberg M, Henricks J, Reinolds R, Khoury G, Jay G (1987) The tat-gene of HTLV-1 induces mesenchymal tumors in transgenic mice. Science 237: 1324-1329
16. Ohashi P, Oeheu S, Buerski K, Pircher H, Ohsashi C, Odermatt B, Malisseu B, Zinkernagel RM, Hengartner H (1991) Ablation of tolerance and induction of diabetes by virus in viral antigen transgenic mice. Cell 65: 305-317
17. Oksenberg JR, Begovich AB, Erlich HA, Steinman L (1993) Genetic factors in multiple sclerosis. JAMA 270 (19): 2362-2369
18. Oldstone MBA (1987) Molecular mimicry and autoimmune disease. Cell 50: 819-820
19. Oldstone MBA (ed) (1989a) Molecular mimicry. Cross-reactivity between microbes and host proteins as a cause of autoimmunity Curr Top Microbiol Immunol 145
20. Oldstone MBA (1989b) Viral persistence. Cell 56: 517-520
21. Oldstone MBA (1991) Molecular anatomy of viral persistence. J Viral 65. 6381-6386
22. b CTL. J Exp M 168: 559-570
23. Oldstone MBA, Nerenberg M, Southern P, Price J, Lewicki H (1991) Virus infection triggers IDDM in a transgenic model: role of the anti-self (virus) immune response. Cell 65. 319-331
24. Ren R, Racaniello V (1992) Human poliovirus receptor gene expression and poliovirus tissue tropism in transgenic mice. J Virol 66. 296-304
25. Ren R, Constantini F, Gorgacz E, Lee J, Racaniello V (1990) Transgenic mice expressing a human poliovirus receptor a new model for poliomyelitis. Cell 63: 353-362
26. Roman L, Simons LF, Hammer RE, Sambrook JF, Getlinig MJH (1990) The expression of influenza virus hemagglutinin in the pancreatic β-cells of transgenic mice results in autoimmune diabetes. Cell 61. 383-396
27. Sadovnick AD, Ebers GC (1993) Epidemiology of multiple sclerosis: a critical overview Can J Neurol Sci 20: 17-29
28. Sinha A, Lopez T, McDevitt H (1990) Autoimmune Disease. the failure of self tolerance. Science 248 1380-1387
29. Toggas S, Masliah E, Rockenstein EH, Rall GF, Abraham CR, Mucke L (1994) Central nervous system damage produced by expression of the HIV-1 coat protein gp120 in transgenic mice Nature 367: 188-193
30. Von Herrath MG, Dockter J, Oldstone MBA (1994a) How virus induces a rapid or slow onset IDDM in a transgenic model. Immunity 1. 231-242
31. Von Herrath MG, Dockter J, Nereberg M, Gairin JE, Oldstone MBA (1994b) Thymic selection and adaptability of CTL responses in transgenic mice expressing a viral protein in the thymus. J Exp Med 180: 1901-1910
32. Whitton JL, Tishon A, Lewicki H, Gebhard J, Cook T, Salvato M, Joly E, Oldstone MBA (1989) Molecular analysis of a five amino-acid cytotoxic T-lymphocyte epitope: an immuno-dominant region, which induces nonreciprocal CTL cross-reactivity J Virol 63(10): 4303-4310
33. Whitton JI (1990) Lymphocytic choriomeningitis virus CTL. Semin Virol 1: 257-261
34. Yoon JW (1990) The role of viruses and environmental factors in induction of diabetes. Curr Top Microbiol Immunol 164: 95-124