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Volumn 47, Issue 2, 1996, Pages 195-208

H- and K- ras mutational profiles in chemically induced liver tumors from B6C3F1 and CD-1 mice

Author keywords

[No Author keywords available]

Indexed keywords

4 BIPHENYLAMINE; BENZO[A]PYRENE; CARCINOGEN; CHRYSENE DERIVATIVE;

EID: 0030065903     PISSN: 00984108     EISSN: None     Source Type: Journal    
DOI: 10.1080/009841096161898     Document Type: Article
Times cited : (40)

References (58)
  • 1
    • 0023264512 scopus 로고
    • Statistical test for the comparison of samples from mutational spectra
    • Adams, W. T., and Skopek, T. R. 1987. Statistical test for the comparison of samples from mutational spectra. J. Mol. Biol. 194:391-396.
    • (1987) J. Mol. Biol. , vol.194 , pp. 391-396
    • Adams, W.T.1    Skopek, T.R.2
  • 2
    • 0026669733 scopus 로고
    • Mutations causing defective splicing in the human hprt gene
    • Anderson, B., Hou, S. M., and Lambert, B. 1992a. Mutations causing defective splicing in the human hprt gene. Environ. Mol. Mutagen. 20:89-95.
    • (1992) Environ. Mol. Mutagen. , vol.20 , pp. 89-95
    • Anderson, B.1    Hou, S.M.2    Lambert, B.3
  • 3
    • 0026707320 scopus 로고
    • Strand specificity for mutations induced by BPDE in the hprt gene in human T-lymphocytes
    • Anderson, B., Falt, S., and Lambert, B. 1992b. Strand specificity for mutations induced by BPDE in the hprt gene in human T-lymphocytes. Mutat. Res. 269:129-140.
    • (1992) Mutat. Res. , vol.269 , pp. 129-140
    • Anderson, B.1    Falt, S.2    Lambert, B.3
  • 4
    • 0027960682 scopus 로고
    • Ras protooncogene activation in dichloroacetic acid-, trichloroethylene- and tetrachloroethylene-induced liver tumors in B6C3F1mice
    • Anna, C. H., Maronpot, R. R., Pereira, M. A., Foley, J. F., Malarkey, D. E., and Anderson, M. W. 1994. Ras protooncogene activation in dichloroacetic acid-, trichloroethylene- and tetrachloroethylene-induced liver tumors in B6C3F1mice. Carcinogenesis 15:2255-2261.
    • (1994) Carcinogenesis , vol.15 , pp. 2255-2261
    • Anna, C.H.1    Maronpot, R.R.2    Pereira, M.A.3    Foley, J.F.4    Malarkey, D.E.5    Anderson, M.W.6
  • 5
    • 0024236909 scopus 로고
    • Oncogene activation in chemical carcinogenesis
    • Balmain, A., and Brown, K. 1988. Oncogene activation in chemical carcinogenesis. Adv. Cancer Res. 51:147-182.
    • (1988) Adv. Cancer Res. , vol.51 , pp. 147-182
    • Balmain, A.1    Brown, K.2
  • 8
    • 0000037422 scopus 로고
    • Metabolic activation and DNA adducts of aromatic amines and nitroaromatic hydrocarbons
    • Chemical Carcinogenesis and Mutagenesis, eds. C. S. Cooper and P. L. Grover, Berlin: Springer-Verlag
    • Beland, F. A., and Kadlubar, F. F. 1990. Metabolic activation and DNA adducts of aromatic amines and nitroaromatic hydrocarbons. In Handbook of Experimental Pharmacology, Vol. 94/I, Chemical Carcinogenesis and Mutagenesis, eds. C. S. Cooper and P. L. Grover, pp. 267-325. Berlin: Springer-Verlag.
    • (1990) Handbook of Experimental Pharmacology , vol.94 , Issue.1 , pp. 267-325
    • Beland, F.A.1    Kadlubar, F.F.2
  • 9
    • 0020972626 scopus 로고
    • Arylamine-DNA adducts in vitro and in vivo—Their role in bacterial mutagenesis and urinary bladder carcinogenesis
    • Beland, F. A., Beranek, D. T., Dooley, K. L., Heflich, R. H., and Kadlubar, F. F. 1983. Arylamine-DNA adducts in vitro and in vivo—Their role in bacterial mutagenesis and urinary bladder carcinogenesis. Environ. Health Perspect. 49:125-134.
    • (1983) Environ. Health Perspect. , vol.49 , pp. 125-134
    • Beland, F.A.1    Beranek, D.T.2    Dooley, K.L.3    Heflich, R.H.4    Kadlubar, F.F.5
  • 11
    • 0023898932 scopus 로고
    • The ras family and human carcinogenesis
    • Bos, J. L. 1988. The ras family and human carcinogenesis. Mutat. Res. 195:255-271.
    • (1988) Mutat. Res. , vol.195 , pp. 255-271
    • Bos, J.L.1
  • 12
    • 0024436733 scopus 로고
    • Mutations at codon 61of the Haras protooncogene in precancerous liver lesions of the B6C3F, mouse
    • Buchmann, A., Mahr, J., Bauer-Hofmann, R., and Schwarz, M. 1989. Mutations at codon 61of the Haras protooncogene in precancerous liver lesions of the B6C3F, mouse. Mol. Carcinogen. 2:121-125.
    • (1989) Mol. Carcinogen. , vol.2 , pp. 121-125
    • Buchmann, A.1    Mahr, J.2    Bauer-Hofmann, R.3    Schwarz, M.4
  • 13
    • 0026092941 scopus 로고
    • Mutation activation of the c-Ha-ras gene in liver tumors of different rodent strains: Correlation with susceptibility to hepatocarcinogenesis
    • Buchmann, A., Bauer-Hofmann, R., Mahr, J., Drinkwater, N. R., Luz, A., and Schwarz, M. 1991. Mutation activation of the c-Ha-ras gene in liver tumors of different rodent strains: Correlation with susceptibility to hepatocarcinogenesis. Proc. Natl. Acad. Sci. USA 88:911-915.
    • (1991) Proc. Natl. Acad. Sci. USA , vol.88 , pp. 911-915
    • Buchmann, A.1    Bauer-Hofmann, R.2    Mahr, J.3    Drinkwater, N.R.4    Luz, A.5    Schwarz, M.6
  • 14
    • 0028034656 scopus 로고
    • Computer program for the analysis of mutational spectra: Application to p53 mutations
    • Cariello, N. F., Piegorsch, W. W., Adams, W. T., and Skopek, T. R. 1994. Computer program for the analysis of mutational spectra: Application to p53 mutations. Carcinogenesis 15:2281-2285.
    • (1994) Carcinogenesis , vol.15 , pp. 2281-2285
    • Cariello, N.F.1    Piegorsch, W.W.2    Adams, W.T.3    Skopek, T.R.4
  • 15
    • 0026063036 scopus 로고
    • DNA strand-specific mutations induced by BcPHDE in the dihydrofolate reductase gene
    • Carothers, A. M., Mucha, J., and Grunberger, D. 1991. DNA strand-specific mutations induced by BcPHDE in the dihydrofolate reductase gene. Proc. Natl. Acad. Sci. USA 88:5749-5753.
    • (1991) Proc. Natl. Acad. Sci. USA , vol.88 , pp. 5749-5753
    • Carothers, A.M.1    Mucha, J.2    Grunberger, D.3
  • 16
    • 0028287098 scopus 로고
    • N-Nitroso N-methylurea-induced rat mammary tumors arise from cells with preexisting oncogene H-ras1gene mutations
    • Cha, R. S., Thilly, W. G., and Zarbl, H. 1994. N-Nitroso N-methylurea-induced rat mammary tumors arise from cells with preexisting oncogene H-ras1gene mutations. Proc. Natl. Acad. Sci. USA 91:3749-3753.
    • (1994) Proc. Natl. Acad. Sci. USA , vol.91 , pp. 3749-3753
    • Cha, R.S.1    Thilly, W.G.2    Zarbl, H.3
  • 17
    • 0027292743 scopus 로고
    • Dose-dependent ras mutation spectra in N-nitrosodiethylamine-induced mouse liver tumors and 4-(Methyl-nitrosoamino)-1-(3-pyri dyl)-1-butanone-induced mouse lung tumors
    • Chen, B., Liu, L., Castonguay, A., Maronpot, R. R., Anderson, M. W., and You, M. 1993. Dose-dependent ras mutation spectra in N-nitrosodiethylamine-induced mouse liver tumors and 4-(methyl-nitrosoamino)-1-(3-pyri dyl)-1-butanone-induced mouse lung tumors. Carcinogenesis 14:1603-1608.
    • (1993) Carcinogenesis , vol.14 , pp. 1603-1608
    • Chen, B.1    Liu, L.2    Castonguay, A.3    Maronpot, R.R.4    Erson, M.W.5    You, M.6
  • 18
    • 0025152226 scopus 로고
    • Effect of excision repair by diploid human fibroblasts on the kinds and locations of mutations induced by BPDE in the coding region of the hprt gene
    • Chen, R. H., Maher, V. M., and McCormick, J. J. 1990. Effect of excision repair by diploid human fibroblasts on the kinds and locations of mutations induced by BPDE in the coding region of the hprt gene. Proc. Natl. Acad. Sci. USA 87:8680-8684.
    • (1990) Proc. Natl. Acad. Sci. USA , vol.87 , pp. 8680-8684
    • Chen, R.H.1    Maher, V.M.2    McCormick, J.J.3
  • 19
    • 0025807132 scopus 로고
    • Lack of a cell cycle dependent strand bias for mutations in the hprt gene by BPDE in excision repair-deficient human cells
    • Chen, R. H., Maher, V. M., and McCormick, J. J. 1991. Lack of a cell cycle dependent strand bias for mutations in the hprt gene by BPDE in excision repair-deficient human cells. Cancer Res. 51:2587-2592.
    • (1991) Cancer Res , vol.51 , pp. 2587-2592
    • Chen, R.H.1    Maher, V.M.2    McCormick, J.J.3
  • 20
    • 0023491231 scopus 로고
    • Carcinogen-DNA adduct formation in the lungs and livers of preweanling CD-1male mice following administration of [H]6-nitrochrysene, [H]6-aminochrysene, and [H]1- 6-dinitropyrene
    • Delclos, K. B., Walker, R. P., Dooley, K. L., Fu, P. P., and Kadlubar, F. F. 1987. Carcinogen-DNA adduct formation in the lungs and livers of preweanling CD-1male mice following administration of [H]6-nitrochrysene, [H]6-aminochrysene, and [H]1- 6-dinitropyrene. Cancer Res. 47:6272-6277.
    • (1987) Cancer Res , vol.47 , pp. 6272-6277
    • Delclos, K.B.1    Walker, R.P.2    Dooley, K.L.3    Fu, P.P.4    Kadlubar, F.F.5
  • 21
    • 0023821530 scopus 로고
    • Metabolism of the carcinogen [H]6-nitrochrysene in the preweanling mouse: Identification of 6-aminochrysene-1,2-dihydrodiol as the probable proximate carcinogenic metabolite
    • Delclos, K. B., El-Bayoumy, K., Hecht, S. S., Walker, R. P., and Kadlubar, F. F. 1988. Metabolism of the carcinogen [H]6-nitrochrysene in the preweanling mouse: Identification of 6-aminochrysene-1,2-dihydrodiol as the probable proximate carcinogenic metabolite. Carcinogenesis 9:1875-1884.
    • (1988) Carcinogenesis , vol.9 , pp. 1875-1884
    • Delclos, K.B.1    El-Bayoumy, K.2    Hecht, S.S.3    Walker, R.P.4    Kadlubar, F.F.5
  • 23
    • 0028179829 scopus 로고
    • Low frequency of H-ras mutations in hepatocellular adenomas and carcinomas and in hepatoblastomas from B6C3F1mice exposed to oxazepam in the diet
    • Devereux, T. R., White, C. M., Sills, R. C., Bucher, J. R., Maronpot, R. R., and Anderson, M. W. 1994. Low frequency of H-ras mutations in hepatocellular adenomas and carcinomas and in hepatoblastomas from B6C3F1mice exposed to oxazepam in the diet. Carcinogenesis 15:1083-1087.
    • (1994) Carcinogenesis , vol.15 , pp. 1083-1087
    • Devereux, T.R.1    White, C.M.2    Sills, R.C.3    Bucher, J.R.4    Maronpot, R.R.5    Anderson, M.W.6
  • 24
    • 0026100163 scopus 로고
    • Incidence of mutations at codon 61 of the Ha-ras gene in liver tumors of mice genetically susceptible and resistant to hepatocarcinogenesis
    • Dragani, T. A., Menenti, G., Colombo, B. M., Falvella, F. S., Gariboldi, M., Pierotti, M. A., and Della Porta, G. 1991. Incidence of mutations at codon 61 of the Ha-ras gene in liver tumors of mice genetically susceptible and resistant to hepatocarcinogenesis. Oncogene 6:333-338.
    • (1991) Oncogene , vol.6 , pp. 333-338
    • Dragani, T.A.1    Menenti, G.2    Colombo, B.M.3    Falvella, F.S.4    Gariboldi, M.5    Pierotti, M.A.6    Della Porta, G.7
  • 25
    • 0024306535 scopus 로고
    • Genetic determinants of hepatocarcinogene-sis in the B6C3F1mouse
    • Drinkwater, N. R., Hanigan, M. H., and Kemp, C. J. 1989. Genetic determinants of hepatocarcinogene-sis in the B6C3F1mouse. Toxicol. Lett. 49:255-265.
    • (1989) Toxicol. Lett. , vol.49 , pp. 255-265
    • Drinkwater, N.R.1    Hanigan, M.H.2    Kemp, C.J.3
  • 26
    • 0004842780 scopus 로고
    • Selection and use of the B6C3F1mouse and F344 rat in long-term bioassays for carcinogenicity
    • H. A. Milman and E. K. Weisburger, Park Ridge, N.J.: Noyes Publications
    • Goodman, D. G., Boorman, G. A., and Strandberg, J. D. 1985. Selection and use of the B6C3F1mouse and F344 rat in long-term bioassays for carcinogenicity. In Handbook of carcinogen testing, eds. H. A. Milman and E. K. Weisburger, pp. 282-325. Park Ridge, N.J.: Noyes Publications.
    • (1985) Handbook of Carcinogen Testing , pp. 282-325
    • Goodman, D.G.1    Boorman, G.A.2    Strandberg, J.D.3
  • 28
    • 0023222283 scopus 로고
    • Mutational activation of oncogenes in animal model systems of carcinogenesis
    • Guerrero, I., and Pellicer, A. 1987. Mutational activation of oncogenes in animal model systems of carcinogenesis. Mutat. Res. 185:293-308.
    • (1987) Mutat. Res. , vol.185 , pp. 293-308
    • Guerrero, I.1    Pellicer, A.2
  • 29
    • 0042534797 scopus 로고
    • Chemical mutagens
    • A. P. Li and R. H. Heflich, Boca Raton, Fla.: CRC Press
    • Heflich, R. H. 1991. Chemical mutagens. In Genetic toxicology, eds. A. P. Li and R. H. Heflich, pp. 143-202. Boca Raton, Fla.: CRC Press.
    • (1991) Genetic Toxicology , pp. 143-202
    • Heflich, R.H.1
  • 31
    • 0026511264 scopus 로고
    • Mutational spectrometry: A general approach for hot-spot point mutations in selectable genes
    • Keohavong, P., and Thilly, W. G. 1992. Mutational spectrometry: A general approach for hot-spot point mutations in selectable genes. Proc. Natl. Acad. Sci. USA 89:4623-4629.
    • (1992) Proc. Natl. Acad. Sci. USA , vol.89 , pp. 4623-4629
    • Keohavong, P.1    Thilly, W.G.2
  • 34
    • 0027370923 scopus 로고
    • Trans-1,2-Dihydro-1,2-dihydroxy-6-aminochrysene is metabolized to form a major adduct with deoxyguanosine and produces mutations in the hprt gene of CHO cells at G:C basepairs
    • Li, E. E., Heflich, R. H., and Delclos, K. B. 1993. trans-1,2-Dihydro-1,2-dihydroxy-6-aminochrysene is metabolized to form a major adduct with deoxyguanosine and produces mutations in the hprt gene of CHO cells at G:C basepairs. Carcinogenesis 14:2109-2114.
    • (1993) Carcinogenesis , vol.14 , pp. 2109-2114
    • Li, E.E.1    Heflich, R.H.2    Delclos, K.B.3
  • 35
    • 0028245344 scopus 로고
    • Relationships of DNA adduct formation, K-ras activating mutations and carcinogenic activities of 6-nitrochrysene and its metabolites in the lungs of CD-1mice
    • Li, E. E., Heflich, R. H., Bucci, T. J., Manjanatha, M. G., Blaydes, B. S., and Delclos, K. B. 1994. Relationships of DNA adduct formation, K-ras activating mutations and carcinogenic activities of 6-nitrochrysene and its metabolites in the lungs of CD-1mice. Carcinogenesis 15:1377-1385.
    • (1994) Carcinogenesis , vol.15 , pp. 1377-1385
    • Li, E.E.1    Heflich, R.H.2    Bucci, T.J.3    Manjanatha, M.G.4    Blaydes, B.S.5    Delclos, K.B.6
  • 37
    • 0023746566 scopus 로고
    • Sequence specificity of mutations induced by BPDE at the endogenous aprt gene in CHO cells
    • Mazur, M., and Glickman, B. W. 1988. Sequence specificity of mutations induced by BPDE at the endogenous aprt gene in CHO cells. Somat. Cell Mol. Genet. 14:393-400.
    • (1988) Somat. Cell Mol. Genet. , vol.14 , pp. 393-400
    • Mazur, M.1    Glickman, B.W.2
  • 38
    • 0027975141 scopus 로고
    • Mutations induced by aromatic amine DNA adducts in pBR322
    • Melchior, W. B., Jr., Marques, M. M., and Beland, F. A. 1994. Mutations induced by aromatic amine DNA adducts in pBR322. Carcinogenesis 15:889-899.
    • (1994) Carcinogenesis , vol.15 , pp. 889-899
    • Melchior, W.B.1    Marques, M.M.2    Beland, F.A.3
  • 40
    • 0027225639 scopus 로고
    • Genotypic mutation analysis by RFLP/PCR
    • Pourzand, C., and Cerutti, P. 1993. Genotypic mutation analysis by RFLP/PCR. Mutat. Res. 288:113-121.
    • (1993) Mutat. Res. , vol.288 , pp. 113-121
    • Pourzand, C.1    Cerutti, P.2
  • 43
    • 0022602565 scopus 로고
    • Detection and identification of activated oncogenes in spontaneously occurring benign and malignant hepatocellular tumors of the B6C3F, mouse
    • Reynolds, S. H., Stowers, S. J., Maronpot, R. R., Anderson, M. W., and Aaronson, S. A. 1986. Detection and identification of activated oncogenes in spontaneously occurring benign and malignant hepatocellular tumors of the B6C3F, mouse. Proc. Natl. Acad. Sci. USA 83:33-37.
    • (1986) Proc. Natl. Acad. Sci. USA , vol.83 , pp. 33-37
    • Reynolds, S.H.1    Stowers, S.J.2    Maronpot, R.R.3    Erson, M.W.4    Aaronson, S.A.5
  • 45
    • 0026708387 scopus 로고
    • Genetic alterations in the 61st codon of the H-ras oncogene isolated from archival sections of hepatic hyperplasias, adenomas and carcinomas in control groups of B6C3F1mouse bioassay studies conducted from 1979 to 1986
    • Richardson, K. K., Helvering, L. H., Copple, D. M., Rexroat, M. A., Linville, D. W., Engelhardt, J. A., Todd, G. C., and Richardson, F. C. 1992a. Genetic alterations in the 61st codon of the H-ras oncogene isolated from archival sections of hepatic hyperplasias, adenomas and carcinomas in control groups of B6C3F1mouse bioassay studies conducted from 1979 to 1986. Carcinogenesis 13:935-941.
    • (1992) Carcinogenesis , vol.13 , pp. 935-941
    • Richardson, K.K.1    Helvering, L.H.2    Copple, D.M.3    Rexroat, M.A.4    Linville, D.W.5    Engelhardt, J.A.6    Todd, G.C.7    Richardson, F.C.8
  • 46
    • 0026772815 scopus 로고
    • Temporal changes in the mutant frequency and mutation spectra of the 61st codon of the H-ras oncogene following exposure of B6C3F1mice to DEN
    • Richardson, K. K., Rexroat, M. A., Helvering, L. M., Copple, D. M., and Richardson, F. C. 1992b. Temporal changes in the mutant frequency and mutation spectra of the 61st codon of the H-ras oncogene following exposure of B6C3F1mice to DEN. Carcinogenesis 13:1277-1279.
    • (1992) Carcinogenesis , vol.13 , pp. 1277-1279
    • Richardson, K.K.1    Rexroat, M.A.2    Helvering, L.M.3    Copple, D.M.4    Richardson, F.C.5
  • 47
    • 0000163138 scopus 로고
    • Isolation of high molecular weight DNA from mammalian cells
    • Cold Spring Harbor, N.Y.: Cold Spring Harbor Laboratory Press
    • Sambrook, J., Fritsch, E. F., and Maniatis, T. 1989. Isolation of high molecular weight DNA from mammalian cells. In Molecular cloning: A laboratory manual, 2nd ed., pp. 9.16-9.19. Cold Spring Harbor, N.Y.: Cold Spring Harbor Laboratory Press.
    • (1989) Molecular Cloning: A Laboratory Manual , pp. 9.16-9.19
    • Sambrook, J.1    Fritsch, E.F.2    Maniatis, T.3
  • 50
    • 0023852502 scopus 로고
    • Detection of activated protooncogenes in N-nitrosodiethylamine-induced liver tumors: A comparison between B6C3F, mice and Fischer 344 rats
    • Stowers, S. J., Wiseman, R. W., Ward, J. M., Miller, E. C., Miller, J. A., Anderson, M. W., and Eva, A. 1988. Detection of activated protooncogenes in N-nitrosodiethylamine-induced liver tumors: A comparison between B6C3F, mice and Fischer 344 rats. Carcinogenesis 9:271-276.
    • (1988) Carcinogenesis , vol.9 , pp. 271-276
    • Stowers, S.J.1    Wiseman, R.W.2    Ward, J.M.3    Miller, E.C.4    Miller, J.A.5    Erson, M.W.6    Eva, A.7
  • 51
    • 0025293818 scopus 로고
    • Detection of ras mutations in human lung cancers by single-strand conformation polymorphism analysis of polymerase chain reaction products
    • Suzuki, Y., Orita, M., Shiraishi, M., Hayashi, K., and Sekiya, T. 1990. Detection of ras mutations in human lung cancers by single-strand conformation polymorphism analysis of polymerase chain reaction products. Oncogene 5:1037-1043.
    • (1990) Oncogene , vol.5 , pp. 1037-1043
    • Suzuki, Y.1    Orita, M.2    Shiraishi, M.3    Hayashi, K.4    Sekiya, T.5
  • 52
    • 0002459290 scopus 로고
    • The value of historical control data
    • H. C. Grice and J. L. Ciminera, New York: Springer-Verlag
    • van Zwieten, M. J., Majka, J. A., Peter, C. P., and Burek, J. D. 1988. The value of historical control data. In Carcinogenecity, eds. H. C. Grice and J. L. Ciminera, pp. 39-51. New York: Springer-Verlag.
    • (1988) Carcinogenecity , pp. 39-51
    • Van Zwieten, M.J.1    Majka, J.A.2    Peter, C.P.3    Burek, J.D.4
  • 53
    • 0027521097 scopus 로고
    • Ras mutations in 2-acetylaminofluorene-induced lung and liver tumors from C3 H/HeJ and (C3HXA/J) F1mice
    • Wang, Y., Wang, Y., Stoner, G., and You, M. 1993. ras mutations in 2-acetylaminofluorene-induced lung and liver tumors from C3 H/HeJ and (C3HXA/J) F1mice. Cancer Res. 53:1620-1624.
    • (1993) Cancer Res , vol.53 , pp. 1620-1624
    • Wang, Y.1    Wang, Y.2    Stoner, G.3    You, M.4
  • 55
    • 0027160625 scopus 로고
    • Dose-dependent differences in the profile of mutations induced by BPDE in the coding region of the hprt gene in CHO V-79 cells
    • Wei, S. J. C., Chang, R. L., Bhachech, N., Cui, X. X., Merkler, K. A., Wong, C. Q., Henning, E., Yagi, H., Jerina, D. M., and Conney, A. H. 1993. Dose-dependent differences in the profile of mutations induced by BPDE in the coding region of the hprt gene in CHO V-79 cells. Cancer Res. 53:3294-3300.
    • (1993) Cancer Res , vol.53 , pp. 3294-3300
    • Wei, S.J.C.1    Chang, R.L.2    Bhachech, N.3    Cui, X.X.4    Merkler, K.A.5    Wong, C.Q.6    Henning, E.7    Yagi, H.8    Jerina, D.M.9    Conney, A.H.10
  • 57
    • 0026062178 scopus 로고
    • Kinds and locations of mutations induced by BPDE in the coding region of the hprt gene in diploid human fibroblasts
    • Yang, J. L., Chen, R. H., Maher, V. M., and McCormick, J. J. 1991. Kinds and locations of mutations induced by BPDE in the coding region of the hprt gene in diploid human fibroblasts. Carcinogenesis 12:71-75.
    • (1991) Carcinogenesis , vol.12 , pp. 71-75
    • Yang, J.L.1    Chen, R.H.2    Maher, V.M.3    McCormick, J.J.4
  • 58
    • 21544459983 scopus 로고
    • Molecular characterization of mutations in the hprt gene of CHO cells induced by benzo[a]pyrene trans-7,8-diol-anti-9,10-epoxide and two nitrated derivatives
    • (abstr.)
    • Zhan, D. J., Heflich, R. H., and Fu, P. P. 1994. Molecular characterization of mutations in the hprt gene of CHO cells induced by benzo[a]pyrene trans-7,8-diol-anti-9,10-epoxide and two nitrated derivatives. Environ. Mol. Mutagen. 23:76 (abstr.).
    • (1994) Environ. Mol. Mutagen. , vol.76 , pp. 23
    • Zhan, D.J.1    Heflich, R.H.2    Fu, P.P.3


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