Camptothecin yield and distribution within Camptotheca acuminata trees cultivated in Louisiana

Canadian Journal of Botany

Volumn 74, Issue 3, 1996, Pages 360-365

  Liu, Zhijun ^a   Adams, John ^b  

^a LOUISIANA STATE UNIVERSITY AGRICULTURAL CENTER   (United States)

^b LOUISIANA TECH UNIVERSITY   (United States)

Author keywords

Biomass; Camptotheca acuminata; Camptothecin content; Camptothecin distribution; Medicinal plants cultivation

Indexed keywords

CAMPTOTHECA ACUMINATA;

EID: 0030065373     PISSN: 00084026     EISSN: None     Source Type: Journal    
DOI: 10.1139/b96-045     Document Type: Article

References (13)

1. Aiyama, R., Nagai, H., Nokata, H., Shinohara, C., and Sawada, S. 1988. A camptothecin derivative from Nothapodytes foetida. Phytochemistry, 27: 3663-3664.
2. Baldwin, I.T., and Ohnmeiss, T. 1994. Coordination of photosynthetic and alkaloidal responses to damage in uninducible and inducible Nicotiana sylvestris. Ecology, 75: 1003-1014.
3. Buta, J.G., and Novak, M.J. 1978. Ind. Eng. Chem. Prod. Res. Dev. 17: 160.
4. Cai, J.-C., and Hutchinson, C.R. 1983. Camptothecin. In The alkaloids Vol. 21. Chemistry and Pharmacology. Edited by A. Brossi. Academic Press, New York. pp. 101-137.
5. Comins, D.L., Hong, H., Saha, J.K., and Jianhua, G. 1994. A six-step synthesis of (±)-camptothecin. J. Org. Chem. 59: 5120-5121.
6. De Luca, V., and Cutler, A.J. 1987. Subcellular localization of enzymes involved in indole alkaloid biosynthesis in Catharanthus roseus. Plant Physiol. 85: 1099-1102.
7. Govindachari, T.R., and Viswanathan, N. 1972. Alkaloids of Mappia foetida. J. Am. Chem. Soc. 11: 3529-3531.
8. Poehland, B.L., Troupe, N., Carte, B.K., and Westley, J.W. 1989. Reversed-phase high-performance liquid chromatographic assay for camptothecin and related alkaloids. J. Chromatogr. 481: 421-427.
9. SAS Institute Inc. 1988. SAS/STAT users's guide, version 6.03 edition. SAS Institute Inc., Cary, N.C.
10. Slichenmyer, W.J., and van Hoff, D.D. 1990. New natural products in cancer chemotherapy. J. Clin. Pharmacol. 30: 770-788.
11. U.S. Department of Agriculture. 1978. Camptotheca acuminata Decaisne (Nyssaceae) Source of camptothecin, an antileukemic alkaloid. U.S. Dep. Agric. Tech. Bull. No. 1415.
12. Wall, M.E., and Wani, M.C. 1991. Antitumour and topoisomerase I inhibition activity of camptothecin and its analogues. In Economic and medicinal plant research. Vol. 5. Plants and traditional medicine, pp. 111-127.
13. Waller, G.R., and Nowacki, E.K. 1978. Alkaloid biology and metabolism in plants. Plenum Press, New York.