Organ specificity of antihypertensive therapy on ocular albumin vascular clearance and albuminuria in the hypertensive diabetic rat

Investigative Ophthalmology and Visual Science

Volumn 37, Issue 2, 1996, Pages 281-289

  Gin, Trevor ^a   Joon, Troy Lim ^a   Panagiotopoulos, Sianna ^a   Cooper, Mark ^a   Taylor, Hugh ^a   Jerums, George ^a  

^a NONE

Author keywords

albuminuria; hypertension; lacidipine perindopril; retina

Indexed keywords

ALBUMIN; CALCIUM CHANNEL; EYE PROTEIN; HYDRALAZINE; HYDROCHLOROTHIAZIDE; LACIDIPINE; PERINDOPRIL; RESERPINE;

ANIMAL CELL; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BLOOD VESSEL PERMEABILITY; CONTROLLED STUDY; DIABETES MELLITUS; HUMAN; HYPERTENSION; MALE; PRIORITY JOURNAL; PROTEINURIA; RAT; RETINA BLOOD VESSEL; URINARY EXCRETION;

ALBUMINURIA; ANGIOTENSIN-CONVERTING ENZYME INHIBITORS; ANIMALS; ANTIHYPERTENSIVE AGENTS; BLOOD PRESSURE; CALCIUM CHANNEL BLOCKERS; CAPILLARY PERMEABILITY; DIABETES MELLITUS, EXPERIMENTAL; DIABETIC RETINOPATHY; DIHYDROPYRIDINES; DRUG THERAPY, COMBINATION; HYDRALAZINE; HYDROCHLOROTHIAZIDE; HYPERTENSION, RENAL; INDOLES; KIDNEY; MALE; ORGAN SPECIFICITY; PERINDOPRIL; RATS; RATS, INBRED SHR; RATS, INBRED WKY; RESERPINE; RETINA; SERUM ALBUMIN;

EID: 0030065053     PISSN: 01460404     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (41)

1. Williamson JR, Kilo C. Capillary basement membrane in diabetes. Diabetes. 1983;32(suppl 2):96-100.
2. Kimmelsteil P, Kim OJ, Beres J. Studies on renal biopsy specimens with the aid of the electron microscope: I: Glomeruli in Diabetes. Am J Clin Path. 1962;38:270-279.
3. Engerman RL. Pathogenesis of diabetic retinopathy. Diabetes. 1989;38:1203-1206.
4. Cunha-Vaz JG. Natural history of diabetic retinopathy. In: Andreani D et al, eds. Diabetic Complications: Epidemiology and Pathogenetic Mechanisms. New York: Raven Press; 1991:171-180.
5. Alm A, Bill A. Ocular circulation. In: Moses RA, Hart WM, eds. Adler's Physiology of the Eye, Clinical Application. 8th ed. St. Louis: CV Mosby; 1987:183-203.
6. Myers BD. Pathophysiology of proteinuria in diabetic glomerular disease. J Hypertens. 1990;8(suppl 1):541-546.
7. Krogsaa B, Lund-Anderssen H, Mehlsen J, Sestoft L. Blood retinal barrier permeability versus diabetes duration and retinal morphology in insulin dependent diabetic patients. Acta Ophthalmol. 1987;65:686-692.
8. Pugliese G, Tilton RG, Speedy A, et al. Effects of very mild versus overt diabetes on vascular haemodynamics and barrier function in rats. Diabetolagia. 1989;32:845-857.
9. Knowler WC, Bennett PH, Ballintine EJ. Increased incidence of retinopathy in diabetics with elevated blood pressure: A six year follow-up study in Pima Indians. N Engl J Med. 1980;302:645-650.
10. Klein R, Klein BEK, Moss SE. The Wisconsin Epidemiological Study of Diabetic Retinopathy: A review. Diabetes Metab Rev. 1989;7:559-570.
11. Parving HH, Viberti GC, Keen H, Christiansen JS, Lassen NA. Haemodynamic factors in the genesis of diabetic microangiopathy. Metabolism. 1983;32:943-949.
12. Parving HH, Hommel E. High blood pressure is a major factor in progression of diabetic nephropathy. J Diabetic Complications. 1988;2:92-95.
13. Cooper ME, Allen TJ, Macmillan P, Bach L, Jerums G, Doyle AE. Genetic hypertension accelerates nephropathy in the streptozotocin diabetic rat. Am J Hypertens. 1988;1:5-10.
14. Soulis-Liparota T, Cooper M, Papazoglou D, Clarke B, Jerums G. Retardation by aminoguanidine of development of albuminuria, mesangial expansion and tissue fluorescence in streptozotocin-induced diabetic rat. Diabetes. 1991;40:1328-1334.
15. Tilton RG, Pugliese G, Faller AM, LaRose LS, Province MA, Williamson JR. Interactions between hypertension and diabetes on vascular function and structure in rats. J Diabetes Complications. 1992;6:187-196.
16. Somani P, Singh HP, Saini RK, Rabinovitch A. Streptozotocin-induced diabetes in the spontaneously hypertensive rat. Metabolism. 1979;28:1075-1077.
17. Bunag RD. Validation in awake rats of a tail-cuff method for assessing systolic blood pressure. J Appl Physiol. 1973;34:279-282.
18. Schmidt FH. Enzymatic determination of glucose and fructose simultaneously. Klin Wochenschr. 1961;39: 1244-1247.
19. Catt KG, Tregear GW, Burger HG, Skermer C. Antibody-coated tube method for radioimmunoassay of growth hormone. Clin Chim Acta. 1970;27:267-279.
20. 131I-labelled human growth hormone of high specific radioactivity. Biochem J. 1963;89:114-123.
21. Lightman S, Rechthand E, Latker C, Palestine A, Rapoport S. Assessment of the permeability of the blood-retinal barrier in hypertensive rats. Hypertension. 1987;10:390-395.
22. Snedecor GW, Cochran WG. Statistical Methods. 7th ed. Ames, IA: Iowa State University; 1980:228-236.
23. Lightman S, Pinter G, Yuen L, Bradbury M. Permeability changes at blood-retinal barrier in diabetes and effect of aldose reductase inhibition. Am J Physiol. 1990;259:R601-R605.
24. Parving H-H, Andersen AR, Smidt UM, Hommel E, Mathiesen ER, Svendsen PA. Effect of antihypertensive treatment on kidney function in diabetic nephropathy. BMJ. 1987;294:1443-1447.
25. Anderson S, Rennke HG, Garcia DL, Brenner BM. Short and long term effects of antihypertensive therapy in the diabetic rat. Kidney Int. 1989;36:526-536.
26. Fabris B, Jackson B, Johnston CI. Salt blocks the renal benefits of ramipril in diabetic hypertensive rats. Hypertension. 1991;17:497-503.
27. Cooper ME, Allen TJ, O'Brien RC, et al. Nephropathy in a model combining genetic hypertension with experimental diabetes: Enalapril versus hydralazine and metoprolol therapy. Diabetes. 1990;39:1575-1579.
28. Lewis EJ, Hunsicker LG, Bain RP, Rohde RD for the Collaborative Study Group. The effect of angiotensin-converting-enzyme inhibition on diabetic nephropathy. N Engl J Med. 1993;329:1456-1462.
29. Franken AAM, Derkx FHM, Man in't Veld AJ, et al. High plasma prorenin in diabetes mellitus and its correlation with some complications. J Clin Endocrinol Metab. 1990;71:1008-1015.
30. Resnick LM. Calcium metabolism in hypertension and allied metabolic disorders. Diabetes Care. 1991;14:505-520.
31. Parving H-H. Impact of blood pressure and antihypertensive treatment on incipient and overt nephropathy, retinopathy, and endothelial permeability in diabetes mellitus. Diabetes Care. 1991;14:260-269.
32. Cunha-Vaz JG, Fonseca JR, de Abrau JRF. Studies on retinal blood flow: II: Diabetic retinopathy. Arch Ophthalmol. 1978;96:809-811.
33. Kohner EM. The problems of retinal blood flow in diabetes. Diabetes. 1976;25(suppl 2):839-844.
34. Grunwald JE, Riva CE, Sinclair SH. Laser Doppler velocimetry study of retinal circulation in diabetes mellitus. Arch Ophthalmol. 1986;104:991-996.
35. McMillan DE. The effect of diabetes on blood flow properties. Diabetes. 1982;23 (suppl 2):56-63.
36. Bresnick GH. The pathophysiology of diabetic retinopathy: An overview. In: Andreani D et al, eds. Diabetic Complications: Epidemiology and Pathogenetic Mechanisms. New York: Raven Press; 1991:187-210.
37. Grunwald JE, Riva CE, Brucker AJ. Altered retinal vascular response to 100% oxygen breathing in diabetes mellitus. Ophthalmology. 1984;91:1447-1452.
38. Sinclair SH, Grunwald JE, Riva CE. Retinal vascular autoregulation in diabetes mellitus. Ophthalmology. 1982;89:748-750.
39. Fallon TJ, Maxwell DL, Kohner EM. Autoregulation of retinal blood flow in diabetic retinopathy measured by the blue-light entoptic technique. Ophthalmology. 1987;94:1410-1415.
40. Patel V, Rassam SMB, Chen HC, Kohner EM. Oxygen reactivity in diabetes mellitus: Effect of hypertension and hyperglycaemia. Clin Sci. 1994;86:689-695.
41. Williamson JR, Chang K, Frangos M, et al. Hyperglycemic pseudohypoxia and diabetic complications. Diabetes. 1993;42:801-813.