Cocaine-induced microvascular vasoconstriction but differential systemic haemodynamic responses in Yucatan versus Yorkshire varieties of swine

British Journal of Pharmacology

Volumn 117, Issue 3, 1996, Pages 559-565

  Miao, Lin ^a,c   Núñez, Boris D ^a,d   Susulic, Vojken ^a   Wheeler, Suzanne ^b   Carrozza, Joseph P ^a   Ross, James N ^b   Morgan, James P ^a  

^a BETH ISRAEL DEACONESS MEDICAL CENTER   (United States)

^b TUFTS UNIVERSITY SCHOOL OF MEDICINE   (United States)

^c BROWN UNIVERSITY   (United States)

^d ST MARY S HOSPITAL   (United States)

Author keywords

Cocaine; Coronary blood flow; Coronary flow reserve; Microcirculation; Microvascular spasm

Indexed keywords

COCAINE;

ANIMAL EXPERIMENT; ARTICLE; CONTROLLED STUDY; CORONARY ARTERY BLOOD FLOW; CORONARY ARTERY CONSTRICTION; CORONARY HEMODYNAMICS; CORONARY VASCULAR RESISTANCE; EPICARDIUM; HEART RATE; HEMODYNAMICS; INTRAVENOUS DRUG ADMINISTRATION; MEAN ARTERIAL PRESSURE; MICROVASCULATURE; NONHUMAN; PRIORITY JOURNAL; STRAIN DIFFERENCE; SWINE; SYSTOLIC BLOOD PRESSURE; VASOCONSTRICTION;

EID: 0030065042     PISSN: 00071188     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1476-5381.1996.tb15227.x     Document Type: Article

References (53)

1. ABEL, F.L., WILSON, S.P., ZHAO, R.R. & FENNEL, W.H. (1989). Cocaine depresses the canine myocardium. Circ. Shock. 28, 309-319.
2. BAYER, H. B. (1938). Epinephrine, cocaine and ergotamine. Arch. Int. Pharmacol. Ther., 58, 103-114.
3. BECKMAN, K.J., PARKER, R.B., HARIMAN, R.J., GALLASTEGUI, J.L. JAVAID, J.I. & BAUMAN, J.I., (1991). Hemodynamic and electrophysiological actions of cocaine. Effects of sodium bicarbonate as an antidote in dogs. Circulation, 83, 1799-1807.
4. BRADLEY, A.B. & MORGAN, K.G. (1987). Alterations in cytoplasmic calcium senstivity during porcine artery contractions as detected by aequorin. J. Physiol., 385, 437.
5. BRAUNWALD, K. & SOBEL, B.E. (1992). Coronary blood (low and myocardial ischemia. In Heart Disease. A Textbook of Cardiovascular Medicine, 4th ed., ed. Braunwald, E. pp. 1161-1199. Philadelphia: W.B. Saunders.
6. BUSH, A.D. (1920). Perfusion of the medulla of the turtle with atropin, caffeine and strichmin. J. Pharmacol. Exp. Ther., 15, 173-183.
7. CATRAVAS, J.D. & WATERS, I.W. (1981). Acute cocaine intoxication in the conscious dog: studies on the mechanism of lethality. J. Pharmacol. Exp. Ther., 217, 350-356.
8. CATRAVAS, J.D., WATERS, I.W., WALTZ, M.A. & DAVIS, W.M. (1978). Acute cocaine intoxication in the conscious dog: pathophysiologic profile of acute lethality. Arch. Int. Pharmacodyn. Ther., 235, 328-340.
9. EGASHIRA, K., PIPERS, F.S. & MORGAN, J.P. (1991). Effects of cocaine on epicardial coronary artery reactivity in miniature swine after endothelial injury and high cholesterol feeding: in vivo and in vitro analysis. J. Clin. Invest., 88, 1307-1314.
10. EGASHIRA, K., TOMOIKE, H., YAMAMOTO, Y., YAMADA, A. & HAYASHI, Y. (1986). Histamine-induced coronary spasm in regions of internal thickening. Circulation, 74, 826.
11. FRAKER, T.D., TEMESY-ARMOS, P.M., BREWSTER, P.S. & WILKERSON, R.D. (1990). Mechanism of cocaine-induced myocardial depression in dogs. Circulation, 81, 1012-1016.
12. GILLIS, R.A., QUEST, J.A. & WILKERSON, R.D. (1992). Underlying mechanisms responsible for cardiovascular disorders associated with cocaine abuse. In Cocaine: Pharmacology. Physiology, and Clinical Strategies, ed. Lakoski, J.M., Galloway, M.P. & White, F.J. pp. 371-390. Boca Raton: CRC Press.
13. GINSBURG, R. (1983). The isolated human epicardial coronary artery. Am. J. Cardiol., 52, 61.
14. GINSBURG, R., BRISTOW, M.R., HARRISON, D.C. & STINSON, E.B. (1980). Studies with isolated human coronary arteries. Some general observations, potential mediators of spasm, role of calcium antagonists. Chest, 78, 180.
15. GONZALEZ, F.A. & BYRD, L.D. (1977). Physiologic effects of cocaine in squirrel monkey. Life Sci., 21, 1417-1421.
16. GRAHAM, M.H., ABBOUD, F.M. & ECKSTEIN, J.W. (1965). Effect of cocaine on cardiovascular responses in dogs. J. Pharmacol. Exp. Ther., 150, 46-52.
17. GROSSMAN, W. & BAIM, D.S. (1991). Evaluation of myocardial blood flow and metabolism. Card. Catheter. Angiogr. Interv., 21, 349.
18. HALE, S.L., ALKER, K.J., REZKALLA, S.H., EISENHAUER, A.C. & KLONER, R.A. (1991). Nifedipine protects the heart from the acute deleterious effects of cocaine if administered before but not after cocaine. Circulation, 83, 1437-1443.
19. HAYES, S.N., MOYER, T.P., MORLEY, D. & BOVE, A.A. (1991). Intravenous cocaine causes epicardial vasoconstriction in the intact dog. Am. Heart J., 121, 1639-1648.
20. HERMAN, E.H. & VICK, J. (1987) A study of direct effect of cocaine on the heart. Fed. Proc., 46, 1146.
21. HOLLANDER, J.D. & CARTER, W.A. (1992). Use of phentolamine for cocaine induced myocardial ischemia. N. Eng. J. Med., 327, 361.
22. ISNER, J.M. & CHOKSHI, S.K. (1991). Cardiovascular complications of cocaine. Curr. Probl. Cardiol., 64, 94-123.
23. ISNER, J.M., ESTES III, N.A., THOMPSON, P.D., COSTANZONORDIN, M.R., SUBRAMANAIAN, R., MILLER, G., KATSAS, G., SWEENEY, K. & STURNER, W.Q. (1986). Acute cardiac events temporally related to cocaine abuse. N. Eng. J. Med., 315, 1438-1443.
24. JOHNSON, M.N., KARAS, S.P., HURSEY, T.L., GILLIS, R.A. & SCHAER, G.L. (1989). Cocaine bingeing produces progressively left ventricular dysfunction. Circulation, 80 (Suppl II): II 15.
25. KOCHMANN, M. & DALES, F. (1908). Wirkung des Kokains auf Warmblüterherz unter besonderer Berücksichtigung der Extrasystole. Arch. Int. Pharmacol., 18, 41-63.
26. KOERKER, R.L., & MORAN, N. (1971). An evaluation of the inability of cocaine to potentiate the responses to cardiac sympathetic nerve stimulation in the dog. J. Pharmacol. Exp. Ther., 178, 482-496.
27. KOSSOWSKEY, W.A. & LYON, A.F. (1984). Cocaine and acute myocardial infarction, a probable connection. Chest, 86, 729-731.
28. KUHN, F.E., GILLlS, R.A., WAHLSTROM, S.K. & VISNER, M.S. (1989). Cocaine induced deleterious effects on the canine coronary circulation (Abstract). J. Am. Coll. Cardiol., 13, 2: 79A.
29. KURODA, M. (1915). Cocaine actions. J. Pharmacol. Exp. Ther., 7, 423-429.
30. LAN, Y.H., MCKEITH, S.K., NOVAKOFSKI, J. & CARR, T.R. (1993). Carcass and muscle characteristics of Yorkshire, Meishan, Yorkshire x Meishan, Engjing x Yorkshire and Minzhu x Yorkshire pigs. J. Animal Sci., 71, 3344-3349.
31. LANGE, R.A., CIGARROA, R.G., YANCY, J.R., WILLARD, J.E., POPMA, J.J., SILLS, M.N., MCBRIDE, W., KIM, A.S. & HILLIS, L.D. (1989). Cocaine-induced coronary artery vasoconstriction. N. Eng. J. Med., 321, 1557-1562.
32. MORCOS, N.C., FAIRHURST, A.S. & HENRY, W.L. (1988). Direct but reversible effects of cocaine on the myocardium. J. Am. Coll. Cardiol., 9, 172A.
33. MORELAND, R.S. & BOHR, D.F. (1984). Adrenergic control of coronary arteries. Fed. Proc., 43, 2857.
34. MOSSO, U. (1887). Über die physiolgische Wirkung des Kokains. Naunyn Schmied. Arch. Exp. Pathol. Pharmacol., 23, 153-208.
35. NANJI, A.A. & FILIPENKO, J.D. (1984). Asystole and ventricular fibrillation assocated with cocaine intoxication. Chest, 85, 132-133.
36. NÚÑEZ, B., MIAO, L., CARROZZA, J., ROSS, J., DOUGLAS, P., GORDON, P., KATZ, S.E., KUNTZ, R. & MORGAN, J.P. (1994a). Cocaine-induced transmural myocardial infarction in a Yorkshire swine with normal coronary arteries: evidence for microvascular and/or epicardial coronary artery spasm. Cardiovasc. Pathol., 3, 93-97.
37. NÚÑEZ, B.D., MIAO, L., CARROZZA, J.P., ROSS, J., GLADSTONE, S., GROSSMAN, W., BAIM, D.S. & MORGAN, J.P. (1993). Effects of cocaine on carotoid artery reactivity in Yorkshire swine after balloon vascular injury: an in vivo and in vitro study (Abstract). J. Am. Coll. Cardiol., 21 (Suppl A): 369A.
38. NÚÑEZ, B.D., MIAO, L., KUNTZ, R.E., ROSS, J.N., GLADSTONE, S., BAIM, D.S., GORDON, P.C., MORGAN, J.P., & CARROZZA, J.P. (1994b). Cardiogenic shock induced by cocaine in swine with normal coronary arteries. Cardiovasc. Res., 28, 105-111.
39. NÚNẼZ, B.D., MIAO, L., WANG, Y., NÚÑEZ, M.M., SELLKE, F.W., ROSS, J.N., ROSS, J.N., VOJKAN, S., PAIK, G.Y., CARROZZA, J.P. & MORGAN, J.P. (1994c). Cocaine-induced microvascular spasm in Yucatan miniature swine: in vivo and in vitro evidence of spasm. Circ. Res., 74, 281-294.
40. 2+ responsiveness of ferret ventricular myocardium. Br. J. Pharmacol., 101, 679-685.
41. PIERRE, S., KOSSOWSKY, W., CHOU, S.T. & ABADIR, A.R. (1985). Coronary and systemic hemodynamics after intravenous injection of cocaine. Anesthesiology, 63, A28.
42. PRUS, J. (1913). Über die Wirkung des Kokains auf das Herz. Ztschr Fed. Exp. Pathol., 14, 161-170.
43. REZKALLA, S.H., HALE, S. & KLONER, R.A. (1990). Cocaine-induced heart diseases. Am. Heart J., 120, 1403-1408.
44. RITCHIE, J.M. & GREENE, N.M. (1990). Cocaine. In The Pharmacological Basis of Therapeutics, 8th ed., ed. Gilman, A.G., Roll, T.W., Nies, A.S. & Taylor, P. pp. 319-320. New York: Pergamon Press.
45. ROTH, G.B. (1917). Cocaine and procainamide. Hyg. Lab, Bull., 20, 109-113.
46. SCHWARTZ, A.B., JANSEN, D., JONES, R.T. & BOYLE, W. (1989). Electrocardiographic and hemodynamic effects of intravenous cocaine in awake and anesthetized dogs. J. Electrocardiol., 22, 159-166.
47. SHIMOKAWA, H., TOMOIKE, H., NABEYAMA, S., YAMAMOTO, H., ARAKI, H., NAKAMURA, M., ISHIJ, Y. & TANAKA, K. (1983). Coronary artery spasm induced in atherosclerotic miniature swine. Science, 221, 560.
48. STAMBLER, B.S., KOMAMURA, K., IHARA, T. & SHANNON, R.P. (1993). Acute intravenous cocaine causes transient depression followed by sustained left ventricular function in conscious dogs. Circulation, 87, 1687-1697.
49. WANG, S.V., NÚÑEZ, B.D., MORGAN, J.P., ROSS, J.N. & SELLKE, F.W. (1994). Cocaine and the porcine coronary microcirculation: effects of chronic cocaine exposure and hypercholesterolemia. J. Cardiothoracic Vas. Anesth., 9, 290-296.
50. WETLI, C.V. & WRIGHT, R.K. (1979). Death caused by recreational cocaine use. J. Am. Med. Assoc., 241, 2519-2522.
51. WILKERSON, R.D. (1988). Cardiovascular effects of cocaine in conscious dogs: importance of fully functional autonomic and central system. J. Pharmacol. Exp. Ther., 246, 466-471.
52. YAMAMOTO, Y., TOMOIKE, H., EGASHIRA, K. & NAKAMURA, M. (1987). Pathogenesis of coronary artery spasm in miniature swine with regional internal thickening after balloon denudation. Circ. Res., 60, 113.
53. ZIMMERMAN, F.H., GUSTAFSON, G.M. & KEMP, H.G. (1987). Recurrent myocardial infarction associated with cocaine abuse in a young man with normal coronaries: evidence for coronary artery spasm culminating in thrombus. J. Am. Coll. Cardiol., 9, 964-968.