Heterogeneous distribution and organization of cytoskeletal proteins drive differential modulation of metabolic fluxes

Journal of Cellular Biochemistry

Volumn 60, Issue 2, 1996, Pages 271-278

  Aon, M A ^a,c   Caceres A ^b   Cortassa, S ^a  

^a UNIVERSIDAD NACIONAL DE TUCUMÁN   (Argentina)

^b INSTITUTO DE INVESTIGACIÓN MÉDICA MERCEDES Y MARTÍN FERREYRA   (Argentina)

^c GOETHE UNIVERSITY   (Germany)

Author keywords

actin; cytoplasmic segregation; cytoskeleton; metabolic fluxes; microtubular protein; topological regulation

Indexed keywords

ACTIN; CYTOSKELETON PROTEIN; G ACTIN; MICROTUBULE PROTEIN; PYRUVATE KINASE; TUBULIN;

ACTIN POLYMERIZATION; ANIMAL TISSUE; ARTICLE; BRAIN TISSUE; CELL METABOLISM; CELLULAR DISTRIBUTION; CONTROLLED STUDY; CYTOARCHITECTURE; DEPOLYMERIZATION; ENZYME ACTIVITY; MATHEMATICAL MODEL; NONHUMAN; PRIORITY JOURNAL; PROTEIN DETERMINATION; PROTEIN LOCALIZATION; PROTEIN POLYMERIZATION; RAT;

ANIMALIA;

EID: 0030064932     PISSN: 07302312     EISSN: None     Source Type: Journal    
DOI: 10.1002/(SICI)1097-4644(19960201)60:2<271::AID-JCB11>3.0.CO;2-Q     Document Type: Article

References (31)

1. Adams AEM, Pringle JR (1984): Relationship of actin and tubulin distribution in wild-type and morphogenetic mutant Saccharomyces cerevisiae. J Cell Biol 98:934-945.
2. Aon MA, Cortassa S (1994): On the fractal nature of cytoplasm. FEBS Lett 344:1-4.
3. Aon MA, Monaco ME, Cortassa S (1995a): Carbon and energetic uncoupling are associated with block of division at different stages of the cell cycle in several cdc mutants of Saccharomyces cerevisiae. Exp Cell Res 217:42-51.
4. Aon MA, Cortassa S, Cáceres A (1995b): Models of cytoplasmic structure and function. In "Proceedings of the International Workshop on Information Processing in Cells and Tissues." Liverpool (accepted).
5. Barnes G, Louie KA, Botstein D (1992): Yeast proteins associated with microtubules in vitro and in vivo. Mol Biol Cell 3:29-47.
6. Carlier MF, Melki R, Pantaloni D, Hill TL, Chen Y (1987): Synchronous oscillations in microtubule polymerization. Proc Natl Acad Sci USA 84:5257-5261.
7. Chant J (1994): Cell polarity in yeast. Trends Genet 10:328-333.
8. Clegg JS (1984): Properties and metabolism of the aqueous cytoplasm and its boundaries. Am J Physiol 246:R133-R151.
9. Clegg JS (1992): Cellular infrastructure and metabolic organization. Curr Topics Cell Regul 33:3-14.
10. Cortassa S, Aon M.A. (1994): Spatio-temporal regulation of glycolysis and oxidative phosphorylation in vivo in tumor and yeast cells. Cell Biol Int 18:687-714.
11. Cortassa S, Cáceres A, Aon MA (1994): Microtubular protein in its polymerized or non polymerized states differentially modulates in vitro and intracellular fluxes catalyzed by enzymes of carbon metabolism. J Cell Biochem 55:120-132.
12. Cuneo P, Magri E, Verzola A, Grazi E (1992): "Macromolecular crowding" is a primary factor in the organization of the cytoskeleton. Biochem J 281:507-512.
13. Feder J (1988): "Fractals." New York: Plenum Press.
14. Fulton A (1982): How crowded is the cytoplasm? Cell 30.345-347.
15. Garner MM, Burg MB (1994): Macromolecular crowding and confinement in cells exposed to hypertonicity. Am J Physiol 266:C877-C892.
16. Hirokawa N (1991): Molecular architecture and dynamics of the neuronal cytoskeleton. In "The Neuronal Cytoskeleton." New York: Wiley-Liss, pp. 5-74.
17. Jacobs ChW, Adams AEM, Szaniszlo PJ, Pringle JR (1988): Functions of microtubules in the Saccharomyces cerevisiae cell cycle. J Cell Biol 107:1409-1426.
18. Kilmartin JV, Adams AEM (1984): Structural rearrangements of tubulin and actin during the cell cycle of the yeast Saccharomyces. J Cell Biol 98:922-933.
19. Knull HR, Walsh JL (1992): Association of glycolytic enzymes with the cytoskeleton. Curr Topics Cell Regul 33: 15-30.
20. Lehotzky A, Telegdi M, Liliom K, Ovádi J (1993): Interaction of phosphofructokinase with tubulin and microtubules. Quantitative evaluation of the mutual effects. J Biol Chem 268:10888-10894.
21. Lew DJ, Reed SI (1993): Morphogenesis in the yeast cell cycle: regulation by cdc28 andcyclins. J Cell Biol 120:1305-1320.
22. Luby-Phelps K, Lanni F, Taylor DL (1988): The submicroscopic properties of cytoplasm as a determinant of cellular function. Annu Rev Biophys Biophys Chem 17:369-396.
23. Minton AP (1992): Confinement as a determinant of macromolecular structure and reactivity. Biophys J 63:1090-1100.
24. Morfini G, DiTella MC, Feiguin F, Carri N, Cáceres A (1994): Neurotrophin-3 enhances neurite outgrowth in cultured hippocampal pyramidal neurons. J Neurosci Res 39:219-232.
25. Mulholland J, Preuss D, Moon A, Wong A, Drubin D, Botstein D (1994): Ultrastructure of the yeast actin cytoskeleton and its association with the plasma membrane. J Cell Biol 125:381-391.
26. Novick P, Botstein D (1985): Phenotypic analysis of temperature-sensitive yeast actin mutants. Cell 40:405-416.
27. Rabouillé C, Cortassa S, Aon MA (1992): Fractal organization in biological macromolecular lattices. J Biomol Struct Dynam 9:1013-1024.
28. Roberts SJ, Somero GN (1987): Binding of phosphofructokinase to filamentous actin. Biochemistry 26:3437-3442.
29. Solomon F (1991): Analyses of the cytoskeleton in Saccharomyces cerevisiae. Annu Rev Cell Biol 7:633-662.
30. Suzuki A, Yamazaki M, Ito T (1989): Osmoelastic coupling in biological structures: formation of parallel bundles of actin filaments in a crystalline-like structure caused by osmotic stress. Biochemistry 28:6513-6518.
31. Welch MD, Holtzman DA, Drubin DG (1994): The yeast actin cytoskeleton. Curr Opin Cell Biol 6:110-119.