Prostate specific antigen releases a kinin-like substance on proteolysis of seminal vesicle fluid that stimulates smooth muscle contraction

Journal of Urology

Volumn 155, Issue 2, 1996, Pages 738-742

  Fichtner, Jan ^a   Graves, Howard C B ^a   Thatcher, Kay ^a   Yemoto, Cheryl ^a   Shortliffe, Linda M D ^a  

^a STANFORD UNIVERSITY MEDICAL CENTER   (United States)

Author keywords

bradykinin; kallikrein; prostate; prostate specific antigen; seminal vesicles

Indexed keywords

BRADYKININ; KALLIKREIN; PROSTATE SPECIFIC ANTIGEN;

ANIMAL EXPERIMENT; ARTICLE; BLADDER CONTRACTION; EJACULATION; ENZYME ACTIVITY; MALE; NONHUMAN; PRIORITY JOURNAL; PROTEIN DEGRADATION; RAT; SEMINAL PLASMA; SEMINAL VESICLE; SMOOTH MUSCLE CONTRACTION; SPERMATOZOON MOTILITY; UTERUS CONTRACTION;

EID: 0030064613     PISSN: 00225347     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0022-5347(01)66512-1     Document Type: Article

References (34)

1. Hartmann, R., Steiner, R., Hofmann, N. and Kaufmann, R.: The effect of the kallikrein-kinin system and prostaglandins E on the motility of human spermatozoa measured by the laser Doppler method. Adv. Exp. Med. Biol., 120B: 311, 1979.
2. Fink, E., Schill, W. B., Fiedler, F., Shimamoto, K., Krassnigg, F. and Frick, J.: The tissue kallikrein-kinin system in human seminal plasma-biochemical and functional aspects. Adv. Exp. Med. Biol., 198A: 291, 1986.
3. Fink, E., Schill, W. B. and Miska, W.: Kinin-containing kininogen is present in human seminal plasma. Adv. Exp. Med. Biol., 247B: 311, 1989.
4. Geiger, R. and Clausitzer, B.: Isolation of an enzymatically active tissue kallikrein from human seminal plasma by immunoaffinity chromatography. Z. Physiol. Chem., 83: 362, 1981.
5. Yokoyama, M., Hiwada, K., Kokubu, T., Takaha, M. and Takeuchi, M.: Angiotensin converting enzyme in human prostate. Clin. Chem., 100: 253, 1980.
6. Krassnigg, F., Niederhauser, H., Fink, E., Frick, J. and Schill, W. B.: Angiotensin converting enzyme (ACE) of human seminal plasma is synthesized by the testis, epididymis and prostate. Int. J. Androl., 12: 22, 1989.
7. Schill, W. B.: Stimulation of sperm motility by kinins in fresh and 24 hours aged human ejaculates. Andrologia, 7: 135, 1975.
8. Cohen, M. L. and Drey, K.: Contractile responses in bladder body, bladder neck and prostate from rat guinea pig and cat. J. Pharmacol. Exp. Ther., 248: 1063, 1989.
9. Catacutan-Labay, P. and Boyarsky, S.: Bradykinin: effect on ureteral peristalsis. Science, 151: 78, 1966.
10. Watt, K. W. K., Lee, P. J., M'Timkulu, T., Chan, W. P. and Loor, R.: Human prostate-specific antigen: structural and functional similarity with serine proteases. Proc. Natl. Acad. Sci. U.S.A., 83: 3166, 1986.
11. Schachter, M.: Kallikreins (kininogenases)-A group of serine proteases with bioregulatory actions. Pharmacol. Rev., 80: 1, 1980.
12. Hara, M., Koyanagi, Y., Inoue, T. and Fukuyama, T.: Some physiochemical characteristics of gamma-seminoprotein, an antigen component specific for human seminal plasma. Jap. J. Legal Med., 25: 322, 1971.
13. Li, T. S. and Belling, C. G.: Isolation and characterization of two specific antigens of human seminal plasma. Fertil. Steril., 24: 134, 1973.
14. Sensabaugh, G. F.: Isolation and characterization of a semen-specific protein from human seminal plasma: a potential new marker for semen identification. J. Forensic Sci., 23: 106, 1978.
15. Graves, H. C. B., Sensabaugh, G. F. and Blake, E. T.: Postcoital detection of a male specific semen protein: application to the investigation of rape. N. Engl. J. Med., 312: 338, 1985.
16. Wang, M. C., Valenzuela, L. A., Murphy, G. P. and Chu, T. M.: Purification of a human prostate specific antigen. Invest. Urol., 17: 159, 1979.
17. Stamey, T. A., Yang, N. A., Hay, A. R., McNeal, J. E., Freiha, F. S. and Redwine, E.: Prostate-specific antigen as a serum marker for adenocarcinoma of the prostate. N. Engl. J. Med., 317: 909, 1987.
18. Ban, Y., Wang, M. C., Watt, K. W. K., Loor, R. M. and Chu, T. M.: The proteolytic activity of human prostate-specific antigen. Biochem. Biophys. Res. Commun., 123: 482, 1984.
19. Lilja, H.: A kallikrein-like serine protease in prostatic fluids cleaves the predominant seminal vesicle protein. J. Clin. Invest., 76: 1899, 1985.
20. Akiyama, K., Nakamura, T., Iwagana, S. and Hara, M.: The chymotrypsin-like activity of human prostate-specific antigen, gamma-seminoprotein. F.E.B.S. Lett., 225: 168, 1987.
21. Lilja, H., Oldbring, J., Rannevik, G. and Laurell, C. B.: Seminal vesicle secreted proteins and their reaction during gelation and liquefaction of human semen. J. Clin. Invest., 80: 281, 1987.
22. McGee, R. S. and Herr, J. C.: Human seminal vesicle-specific antigen is a substrate for prostate-specific antigen (or p30). Biol. Reprod., 39: 499, 1988.
23. Cohen, P., Graves, H. C. B., Peehl, D., Kamarei, M., Giudice, L. and Rosenfeld, R. G.: Prostate-specific antigen (PSA) is an insulin-like growth factor binding protein-3 protease found in seminal plasma. J. Clin. Endocrinol. Metab., 75: 1046, 1993.
24. Whalley, E. T.: The action of bradykinin and oxytocin on the isolated whole uterus and myometrium of the rat in oestrus. Br. J. Pharmacol., 64: 21, 1978.
25. Sensabaugh, G. F. and Blake, E. T.: Seminal plasma protein p30: simplified purification and evidence for identity with prostate-specific antigen. J. Urol., 144: 1523, 1990.
26. Graves, H. C. B., Kamarei, M. and Stamey, T. A.: Identity of prostate specific antigen and the semen protein p30 purified by a rapid chromatography technique. J. Urol., 144: 1510, 1990.
27. Stamey, T. A., Teplow, D. B. and Graves, H. C. B.: Identity of PSA purified from seminal fluid by different methods: comparison by amino acid analysis and assigned extinction coefficients. Prostate, 27: 198, 1995.
28. Shimamoto, K., Chao, J. and Margolius, H. S.: The radioimmunoassay of human urinary kallikrein and comparisons with kallikrein activity measurements. J. Clin. Endocrinol. Metab., 51: 840, 1980.
29. Harper, J. W., Hemmi, K. and Powers, J. C.: Reaction of serine proteases with substituted isocumarins: discovery of 3,4-dichloroisocumarin, a new general mechanism based serine protease inhibitor. Biochemistry, 24: 1831, 1985.
30. Vavrek, R. J. and Stewart, J. S.: Kinin-antagonists: design and activities. J. Cardiovasc. Pharmacol., suppl 6, 15: S69, 1990.
31. Smyth, T. B., Shortliffe, L. M. D. and Constantinou, C. E.: The effect of urinary flow and bladder fullness on renal pelvic pressure in a rat model. J. Urol., 146: 592, 1991.
32. Christensson, A., Laurell, C. B. and Lilja, H.: Enzymatic activity of prostate-specific antigen and its reactions with extracellular serine proteinase inhibitors. Eur. J. Biochem., 194: 755, 1990.
33. Powers, J. C., Odake, S., Ueda, T., Hudig, D., Graves, H. C. B., Kamarei, M. and Kam, C. M.: Synthetic substrates and inhibitors for serine proteases from lymphocytes, mast cells, semen and blood. In: Recent progress on Kinins. Part I. Pharmacological and clinical aspects of the kallikrein-kinin system. Agents Actions, suppl. 38/II: 128, 1992.
34. Paradis, G., Tremblay, R. R. and Dube, J. Y.: Looking for the human glandular kallikrein-1 in the prostate. Prostate, 15: 343, 1989.