Estrogen modulates the dimensions of the lung's gas-exchange surface area and alveoli in female rats

American Journal of Physiology - Lung Cellular and Molecular Physiology

Volumn 270, Issue 1 14-1, 1996, Pages

  Massaro, Gloria D ^a   Mortola, Jacopo P ^b   Massaro, Donald ^b  

^a GEORGETOWN UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b NONE

Author keywords

carbon dioxide production; lactation; oxygen consumption; pregnancy; stereology

Indexed keywords

ANDROGEN; ANDROGEN RECEPTOR; CARBON DIOXIDE; ESTROGEN;

ANDROGEN THERAPY; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; ESTROGEN THERAPY; FEMALE; GAS EXCHANGE; LACTATION; LUNG ALVEOLUS; LUNG GAS EXCHANGE; NONHUMAN; OVARIECTOMY; OXYGEN CONSUMPTION; PREGNANCY; PRIORITY JOURNAL; RAT; SEX DIFFERENCE; STEREOLOGY; VIRILIZATION;

EID: 0030064516     PISSN: 10400605     EISSN: None     Source Type: Journal    
DOI: 10.1152/ajplung.1996.270.1.l110     Document Type: Article

References (25)

1. Asmussen, E. Muscular exercise. In: Handbook of Physiology. Respiration. Washington, DC: Am. Physiol. Soc., 1965, sect. 3, vol. 2, chapt. 36, p. 939-978.
2. Bardin, C. W., and J. F. Catterall. Testosterone: a major determinant of extragenital sexual dimorphism. Science Wash. DC 211: 1285-1294, 1981.
3. Barraclough, C. A. Production of anovulatory, sterile rats by single injections of testosterone propionate. Endocrinology 68: 62-67, 1961.
4. 2. Am. J. Physiol. 261 (Lung Cell. Mol. Physiol. 5): L370-L377, 1991.
5. Blanco, L., G. D. Massaro, and D. Massaro. Alveolar dimensions and number: developmental and hormonal regulation. Am. J. Physiol. 257 (Lung Cell. Mol. Physiol. 1): L240-L247, 1989.
6. Callas, G., and V. T. Adkisson. The effects of desiccated thyroid on the rat lung. Anat. Rec. 197: 331-337, 1980.
7. Cruz-Orive, L. M. Particle number can be estimated using a disector of unknown thickness: the selector. J. Microsc. Oxf. 145: 121-142, 1987.
8. Cruz-Orive, L. M., and E. R. Weibel. Sampling designs for stereology. J. Microsc. Oxf. 122: 235-257, 1981.
9. Diamond, J. Evolutionary design of intestinal nutrient absorption: enough but not too much. News Physiol. Sci. 6: 92-96, 1991.
10. Diamond, J., and K. Hammond. The matches, achieved by natural selection, between biological capacities and their natural loads. Experientia Basel 48: 551-557, 1992.
11. Duncan, D. B. Multiple range and F tests. Biometrics 11: 1-42, 1955.
12. Perńandez, A., M. Abelenda, M.-P. Nava, and M. Puerta. Oxygen consumption of oestradiol-treated rats. Pfluegers Arch. 426: 351-353, 1994.
13. Gehr, P., D. K Mwangi, A. Ammann, G. M. O. Maloiy, C. R. Taylor, and E. R. Weibel. Design of the mammalian respiratory system. V. Scaling morphometric pulmonary diffusion capacity to body mass: wild and domestic mammals. Respir. Physiol. 44: 61-86, 1981.
14. Gundersen, H. J. G., and E. B. Jensen. Stereological estimation of the volume-weighted mean volume of arbitrary particles observed on random sections. J. Microsc. Oxf. 138: 127-142, 1985.
15. Joss, E. E., K. A. Zuppinger, and E. H. Sobel. Effect of testosterone propionate and methyl testosterone on growth and skeletal maturation in rats. Endocrinology 72: 123-130, 1963.
16. Kochakian, C. D., and B. Endahl. Changes in body weight of normal and castrated rats by different doses of testosterone proprionate. Proc. Soc. Exp. Biol. Med. 100: 520-522, 1959.
17. Kramer, C. Y. Extension of multiple range tests to group means with unequal numbers of replication. Biometrics 12: 307-310, 1956.
18. Massaro, G. D., and D. Massaro. Formation of alveoli in rats: postnatal effect of dexamethasone. Am. J. Physiol. 263 (Lung Cell. Mol. Physiol. 7): L37-L41, 1992.
19. Massaro, G. D., J. P. Mortola, and D. Massaro. Sexual dimorphism in the architecture of the lung's gas-exchange region. Proc. Natl. Acad. Sci. USA 92: 1105-1107, 1995.
20. Saiki, C., T. Matsuoka, and J. P. Mortola. Metabolicventilatory interaction in conscious rats: effect of hypoxia and ambient temperature. J. Appl. Physiol. 76: 1594-1599, 1994.
21. Scherle, W. A. A simple method for volumetry of organs in quantitative stereology. Mikroskopie 26: 57-60, 1970.
22. Snedecor, G. W., and W. G. Cochran. Statistical Methods (7th ed.). Ames, IA: Iowa State Univ. Press, 1980, p. 83-106.
23. Tenney, S. M., and J. E. Remmers. Comparative quantitative morphology of the mammalian lung: diffusion area. Nature Lond. 197: 54-56, 1963.
24. Thompson, M. E. Lung growth in response to altered metabolic demand in hamsters: influence of thyroid function and cold. Respir. Physiol. 40: 335-347, 1980.
25. Weibel, E. R. Stereological Methods. New York: Academic, 1979, vol. 1, p. 9-196.