Influence of gastric acid secretion blockade and food intake on the bioavailability of a potassium diclofenac suspension in healthy male volunteers

International Journal of Clinical Pharmacology and Therapeutics

Volumn 34, Issue 2, 1996, Pages 76-79

  Poli, A ^b   Moreno, R A ^a   Ribeiro, W ^a   Dias, H B ^a   Moreno Jr , H ^a   Muscara M N ^a   De Nucci, G ^a  

^a UNIVERSITY OF CAMPINAS   (Brazil)

^b FEDERAL UNIVERSITY OF SANTA CATARINA   (Brazil)

Author keywords

Bioavailability; Drug interaction; Food intake; Gastric acid blockade; Human volunteer pharmacokinetics; Omeprazole; Potassium diclofenac suspension

Indexed keywords

DICLOFENAC POTASSIUM; OMEPRAZOLE;

ADULT; ANALGESIA; AREA UNDER THE CURVE; ARTICLE; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DIET RESTRICTION; DOUBLE BLIND PROCEDURE; DRUG ABSORPTION; DRUG BIOAVAILABILITY; DRUG BLOOD LEVEL; DRUG CLEARANCE; DRUG ELIMINATION; DRUG HALF LIFE; FOOD INTAKE; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HUMAN; HUMAN EXPERIMENT; MALE; NORMAL HUMAN; STATISTICAL ANALYSIS; STOMACH ACID SECRETION; STOMACH PH; ULTRAVIOLET RADIATION;

ADMINISTRATION, ORAL; ADULT; ANTI-INFLAMMATORY AGENTS, NON-STEROIDAL; AREA UNDER CURVE; BIOLOGICAL AVAILABILITY; DICLOFENAC; DRUG INTERACTIONS; EATING; ENZYME INHIBITORS; GASTRIC ACID; HALF-LIFE; HUMANS; HYDROGEN-ION CONCENTRATION; MALE; MIDDLE AGED; OMEPRAZOLE; REFERENCE VALUES; STOMACH; SUSPENSIONS;

EID: 0030064161     PISSN: 09461965     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

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