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Volumn 51, Issue 11, 1996, Pages 1553-1561

Cell cycle-dependent inhibition of the proliferation of human neural tumor cell lines by iron chelators

Author keywords

cell cycle; desferrioxamine; DNA synthesis; iron chelators; neural tumors

Indexed keywords

CHELATING AGENT; DEFEROXAMINE MESYLATE; RAZOXANE;

EID: 0030063939     PISSN: 00062952     EISSN: None     Source Type: Journal    
DOI: 10.1016/0006-2952(96)00099-8     Document Type: Article
Times cited : (53)

References (55)
  • 1
    • 0028219018 scopus 로고
    • Iron-chelating agents in non-iron overload conditions
    • Voest EE, Vreugdenhil G and Marx JJM, Iron-chelating agents in non-iron overload conditions. Ann Intern Med 120: 490-499, 1994.
    • (1994) Ann Intern Med , vol.120 , pp. 490-499
    • Voest, E.E.1    Vreugdenhil, G.2    Marx, J.J.M.3
  • 2
    • 0023092624 scopus 로고
    • Antineurohlastoma activity of desferoxamine in human cell lines
    • Blatt J and Stitely S, Antineurohlastoma activity of desferoxamine in human cell lines. Cancer Res 47: 1749-1750, 1987.
    • (1987) Cancer Res , vol.47 , pp. 1749-1750
    • Blatt, J.1    Stitely, S.2
  • 3
    • 0024241764 scopus 로고
    • Deferoxamine inhibition of human neuroblastoma viability and proliferation
    • Becton DL and Bryles P, Deferoxamine inhibition of human neuroblastoma viability and proliferation. Cancer Res 48: 7189-7192, 1988.
    • (1988) Cancer Res , vol.48 , pp. 7189-7192
    • Becton, D.L.1    Bryles, P.2
  • 8
    • 0025726827 scopus 로고
    • Failure to alter the course of acute myelogenous leukemia in the rat with subcutaneous deferoxamine
    • Blatt J, Boegel F, Hedlund BE, Arena VC and Shadduck RK, Failure to alter the course of acute myelogenous leukemia in the rat with subcutaneous deferoxamine. Leuk Res 15: 391-394, 1991.
    • (1991) Leuk Res , vol.15 , pp. 391-394
    • Blatt, J.1    Boegel, F.2    Hedlund, B.E.3    Arena, V.C.4    Shadduck, R.K.5
  • 9
    • 0018777993 scopus 로고
    • Studies in desferrioxamine and ferroxamine metabolism in normal and iron-loaded subjects
    • Summers MR, Jacobs A, Tudway D and Perera P, Studies in desferrioxamine and ferroxamine metabolism in normal and iron-loaded subjects. Br J Haematol 42: 547-555, 1979.
    • (1979) Br J Haematol , vol.42 , pp. 547-555
    • Summers, M.R.1    Jacobs, A.2    Tudway, D.3    Perera, P.4
  • 11
    • 0025827421 scopus 로고
    • Growth, ribonucleotide reductase and metals in murine leukemic lymphocytes
    • Oblender M and Carpentieri U, Growth, ribonucleotide reductase and metals in murine leukemic lymphocytes. J Cancer Res Clin Oncol 17: 444-448, 1991.
    • (1991) J Cancer Res Clin Oncol , vol.17 , pp. 444-448
    • Oblender, M.1    Carpentieri, U.2
  • 12
    • 0026782447 scopus 로고
    • Cell cycle synchronization and growth inhibition by 3-hydroxypyridin-4-one iron chelators in leukemia cell lines
    • Hoyes KP, Hider RC and Porter JB, Cell cycle synchronization and growth inhibition by 3-hydroxypyridin-4-one iron chelators in leukemia cell lines. Cancer Res 52: 4591-4599, 1992.
    • (1992) Cancer Res , vol.52 , pp. 4591-4599
    • Hoyes, Kp.1    Hider, R.C.2    Porter, J.B.3
  • 13
    • 0027521831 scopus 로고
    • Role of ribonucleotide reductase in inhibition of mammalian cell cycle growth by potent iron chelators
    • Nyholm S, Mann GJ, Johansson AG, Bergeron RJ, Graslund A and Thelander L, Role of ribonucleotide reductase in inhibition of mammalian cell cycle growth by potent iron chelators. J Biol Chem 268: 26200-26205, 1993.
    • (1993) J Biol Chem , vol.268 , pp. 26200-26205
    • Nyholm, S.1    Mann, G.J.2    Johansson, A.G.3    Bergeron, R.J.4    Graslund, A.5    Thelander, L.6
  • 14
    • 0021259518 scopus 로고
    • Deferioxamine: A reversible S-phase inhibitor of human lymphocyte proliferation
    • Lederman HM, Cohen A, Lee JWW, Freedman MH and Gelfand EW, Deferioxamine: A reversible S-phase inhibitor of human lymphocyte proliferation. Blood 64: 748-753, 1984.
    • (1984) Blood , vol.64 , pp. 748-753
    • Lederman, H.M.1    Cohen, A.2    Lee, J.W.W.3    Freedman, M.H.4    Gelfand, E.W.5
  • 15
    • 0023605740 scopus 로고
    • Microbial iron chelator-induced cell cycle synchronization in L1210 cells: Potential in combination chemotherapy
    • Bergeron RJ and Ingeno MJ, Microbial iron chelator-induced cell cycle synchronization in L1210 cells: Potential in combination chemotherapy. Cancer Res 47: 6010-6016, 1987.
    • (1987) Cancer Res , vol.47 , pp. 6010-6016
    • Bergeron, R.J.1    Ingeno, M.J.2
  • 16
    • 0026095172 scopus 로고
    • The effect of desferrioxamine on cell proliferation in human tumor cell lines
    • Siegers C-P, Bumann D and Baretton G, The effect of desferrioxamine on cell proliferation in human tumor cell lines. Toxicol In Vitro 5: 427-430, 1991.
    • (1991) Toxicol In Vitro , vol.5 , pp. 427-430
    • Siegers, C.-P.1    Bumann, D.2    Baretton, G.3
  • 17
    • 0023689207 scopus 로고
    • Mechanism of antineuroblastoma activity of deferoxamine in vitro
    • Blatt J, Taylor SR and Stitely S, Mechanism of antineuroblastoma activity of deferoxamine in vitro. J Lab Clin Med 112: 433-436, 1988.
    • (1988) J Lab Clin Med , vol.112 , pp. 433-436
    • Blatt, J.1    Taylor, S.R.2    Stitely, S.3
  • 18
    • 0024348430 scopus 로고
    • Comparison of activity of deferoxamine with that of oral iron chelators against human neuroblastoma cell lines
    • Blatt J, Taylor SR and Kontoghiorghes GJ, Comparison of activity of deferoxamine with that of oral iron chelators against human neuroblastoma cell lines. Cancer Res 49: 2925-2927, 1989.
    • (1989) Cancer Res , vol.49 , pp. 2925-2927
    • Blatt, J.1    Taylor, S.R.2    Kontoghiorghes, G.J.3
  • 20
    • 0022651531 scopus 로고
    • The effect of desferrioxamine on transferrin receptors, the cell cycle and growth rates of human leukaemia cells
    • Bomford A, Issac J, Roberts S, Edwards A, Young S and Williams R, The effect of desferrioxamine on transferrin receptors, the cell cycle and growth rates of human leukaemia cells. Biochem J 236: 243-249, 1986.
    • (1986) Biochem J , vol.236 , pp. 243-249
    • Bomford, A.1    Issac, J.2    Roberts, S.3    Edwards, A.4    Young, S.5    Williams, R.6
  • 21
  • 22
    • 0020398870 scopus 로고
    • Metal binding by pharmaceuticals. Part 2. Interactions of Ca(II), Cu(II), Fe(II), Mg(II), Mn(II) and Zn(II) with the intracellular hydrolysis product of the antitumour agent ICRF 159 and its inactive homologue ICRF192
    • Huang ZX, May PM, Quilan KM, Williams DR and Creighton AM, Metal binding by pharmaceuticals. Part 2. Interactions of Ca(II), Cu(II), Fe(II), Mg(II), Mn(II) and Zn(II) with the intracellular hydrolysis product of the antitumour agent ICRF 159 and its inactive homologue ICRF192. Agents Actions 12: 536-542, 1982.
    • (1982) Agents Actions , vol.12 , pp. 536-542
    • Huang, Z.X.1    May, P.M.2    Quilan, K.M.3    Williams, D.R.4    Creighton, A.M.5
  • 23
    • 0024573486 scopus 로고
    • The interaction of the cardioprotective agent ICRF-187 ((±)-1,2-bis(3,5-dioxopiperazine-1-yl)propane); its hydrolysis product (ICRF-198); and other chelating agents with the Fe(III) and Cu(II) complexes with adriamycin
    • Hasinoff BB, The interaction of the cardioprotective agent ICRF-187 ((±)-1,2-bis(3,5-dioxopiperazine-1-yl)propane); its hydrolysis product (ICRF-198); and other chelating agents with the Fe(III) and Cu(II) complexes with adriamycin. Agents Actions 26: 378-385, 1989.
    • (1989) Agents Actions , vol.26 , pp. 378-385
    • Hasinoff, B.B.1
  • 24
    • 0014938009 scopus 로고
    • Mode of action of the cytostatic agent 'ICRF 159'
    • Sharpe HBA, Field EO and Hellman K, Mode of action of the cytostatic agent 'ICRF 159'. Nature 226: 524-526, 1970.
    • (1970) Nature , vol.226 , pp. 524-526
    • Sharpe, H.B.A.1    Field, E.O.2    Hellman, K.3
  • 25
    • 0017389485 scopus 로고
    • Changes in sensitivity to radiation and ICRF 159 during the life of monolayer cultures of EMT6 tumour line
    • Taylor IW and Bleehen NM, Changes in sensitivity to radiation and ICRF 159 during the life of monolayer cultures of EMT6 tumour line. Br J Cancer 35: 587-594, 1977.
    • (1977) Br J Cancer , vol.35 , pp. 587-594
    • Taylor, I.W.1    Bleehen, N.M.2
  • 26
    • 0021863965 scopus 로고
    • Estimation of nonproliferating cells in the neural retina of embryonic chicks by flow cytometry
    • Morris VB and Taylor IW, Estimation of nonproliferating cells in the neural retina of embryonic chicks by flow cytometry. Cytometry 6: 375-380, 1985.
    • (1985) Cytometry , vol.6 , pp. 375-380
    • Morris, V.B.1    Taylor, I.W.2
  • 27
    • 0026763513 scopus 로고
    • In vitro effects of three iron chelators on mitogen-activated lymphocytes: Identification of differences in their mechanisms of action
    • van Reyk DM, Sarel S and Hunt NH, In vitro effects of three iron chelators on mitogen-activated lymphocytes: Identification of differences in their mechanisms of action, Int J Immunopharmacol 14: 925-932, 1992.
    • (1992) Int J Immunopharmacol , vol.14 , pp. 925-932
    • Van Reyk, D.M.1    Sarel, S.2    Hunt, N.H.3
  • 28
    • 0023198521 scopus 로고
    • Four permanent cell lines established from human malignant gliomas: Three exhibiting striated muscle differentiation
    • Jacobsen PF, Jenkyn DJ and Papadimitriou JM, Four permanent cell lines established from human malignant gliomas: Three exhibiting striated muscle differentiation. J Neuropathol Exp Neurol 46: 431-450, 1987.
    • (1987) J Neuropathol Exp Neurol , vol.46 , pp. 431-450
    • Jacobsen, P.F.1    Jenkyn, D.J.2    Papadimitriou, J.M.3
  • 29
    • 0026535637 scopus 로고
    • Iron deprivation decreases ribonucleotide reductase activity and DNA synthesis
    • Furukawa T, Naitoh Y, Kohno H, Tokunaga R and Taketani S, Iron deprivation decreases ribonucleotide reductase activity and DNA synthesis. Life Sci 50: 2059-2065, 1992.
    • (1992) Life Sci , vol.50 , pp. 2059-2065
    • Furukawa, T.1    Naitoh, Y.2    Kohno, H.3    Tokunaga, R.4    Taketani, S.5
  • 30
    • 0026347398 scopus 로고
    • Mechanism of assembly of the tyrosyl radicaldinuclear iron cluster cofactor of ribonucleotide reductase
    • Bollinger JM, Edmondson DE, Hynh BM, Filley J, Norton JR and Stubbe J, Mechanism of assembly of the tyrosyl radicaldinuclear iron cluster cofactor of ribonucleotide reductase. Science 253: 292-298, 1991.
    • (1991) Science , vol.253 , pp. 292-298
    • Bollinger, J.M.1    Edmondson, D.E.2    Hynh, B.M.3    Filley, J.4    Norton, J.R.5    Stubbe, J.6
  • 31
    • 0025259330 scopus 로고
    • Effects of iron, copper and zinc on the activity of ribonucleotide reductase in normal leukaemic human lymphocytes
    • Oblender M and Carpentieri U, Effects of iron, copper and zinc on the activity of ribonucleotide reductase in normal leukaemic human lymphocytes. Anticancer Res 10: 123-128, 1990.
    • (1990) Anticancer Res , vol.10 , pp. 123-128
    • Oblender, M.1    Carpentieri, U.2
  • 32
    • 0024343393 scopus 로고
    • Antileukemic effects of deferoxamine on human myeloid leukemia cell lines
    • Becton DL and Roberts B, Antileukemic effects of deferoxamine on human myeloid leukemia cell lines. Cancer Res 49: 4809-4812, 1989.
    • (1989) Cancer Res , vol.49 , pp. 4809-4812
    • Becton, D.L.1    Roberts, B.2
  • 33
    • 0026611745 scopus 로고
    • rb phosphorylation during cell cycle progression of normal human T cells
    • rb phosphorylation during cell cycle progression of normal human T cells. J Immunol 148: 1804-1811, 1992.
    • (1992) J Immunol , vol.148 , pp. 1804-1811
    • Lucas, J.J.1    Terada, N.2    Szepesi, A.3    Gefland, E.W.4
  • 34
    • 0026568215 scopus 로고
    • Cell cycle regulation of the human cdc2 gene
    • Dalton S, Cell cycle regulation of the human cdc2 gene. EMBO J 11: 1797-1804, 1992.
    • (1992) EMBO J , vol.11 , pp. 1797-1804
    • Dalton, S.1
  • 35
    • 0027213013 scopus 로고
    • Definition of the roles for iron and essential fatty acids in cell cycle progression of normal human T lymphocytes
    • Terada N, Or R, Szepesi A, Lucas JJ and Gefland EW, Definition of the roles for iron and essential fatty acids in cell cycle progression of normal human T lymphocytes. Exp Cell Res 204: 260-267, 1993.
    • (1993) Exp Cell Res , vol.204 , pp. 260-267
    • Terada, N.1    Or, R.2    Szepesi, A.3    Lucas, J.J.4    Gefland, E.W.5
  • 36
    • 0019821897 scopus 로고
    • Effects of the l isomer (+)-1,2-bis(3,5-dioxopiperazine-1-yl)propane on cell survival and cell cycle progression of cultured mammalian cells
    • Traganos F, Darzynkiewicz Z and Melamed MR, Effects of the L isomer (+)-1,2-bis(3,5-dioxopiperazine-1-yl)propane on cell survival and cell cycle progression of cultured mammalian cells. Cancer Res 41: 4566-4576, 1981.
    • (1981) Cancer Res , vol.41 , pp. 4566-4576
    • Traganos, F.1    Darzynkiewicz, Z.2    Melamed, M.R.3
  • 37
    • 0025905393 scopus 로고
    • Inhibition of human hepatocellular carcinoma and hepatoblastoma cell lines by deferoxamine
    • Tabor E and Kim CM, Inhibition of human hepatocellular carcinoma and hepatoblastoma cell lines by deferoxamine. J Med Virol 34: 45-50, 1991.
    • (1991) J Med Virol , vol.34 , pp. 45-50
    • Tabor, E.1    Kim, C.M.2
  • 38
    • 0025743989 scopus 로고
    • Nuclear protein B23 translocation after deferoxamine treatment in a human leukaemia cell line
    • Yung Y-M, Yang YH and Bor AM-S, Nuclear protein B23 translocation after deferoxamine treatment in a human leukaemia cell line. Int J Cancer 48: 779-784, 1991.
    • (1991) Int J Cancer , vol.48 , pp. 779-784
    • Yung, Y.-M.1    Yang, Y.H.2    Bor, A.M.-S.3
  • 39
    • 0022256894 scopus 로고
    • Iron metabolism in K562 erythroleukemic cells
    • Bottomley SS, Wolfe LC and Bridges KR, Iron metabolism in K562 erythroleukemic cells. J Biol Chem 260: 6811-6815, 1985.
    • (1985) J Biol Chem , vol.260 , pp. 6811-6815
    • Bottomley, S.S.1    Wolfe, L.C.2    Bridges, K.R.3
  • 40
    • 0028158768 scopus 로고
    • The effect of the iron(III) chelator, desferrioxamine, on iron and transferrin uptake by the human malignant melanoma cell
    • Richardson D, Ponka P and Baker E, The effect of the iron(III) chelator, desferrioxamine, on iron and transferrin uptake by the human malignant melanoma cell. Cancer Res 54: 685-689, 1994.
    • (1994) Cancer Res , vol.54 , pp. 685-689
    • Richardson, D.1    Ponka, P.2    Baker, E.3
  • 41
    • 0018145231 scopus 로고
    • Superoxide-dependent formation of hydroxyl radicals in the presence of iron chelates
    • Halliwell B, Superoxide-dependent formation of hydroxyl radicals in the presence of iron chelates. FEBS Lett 92: 321-326, 1978.
    • (1978) FEBS Lett , vol.92 , pp. 321-326
    • Halliwell, B.1
  • 42
    • 0024355546 scopus 로고
    • Oxygen-based free radical generation by ferrous ions and deferoxamine
    • Klebanoff SJ, Waltersdorph AM, Michel BR and Rosen H, Oxygen-based free radical generation by ferrous ions and deferoxamine. J Biol Chem 264: 19765-19771, 1989.
    • (1989) J Biol Chem , vol.264 , pp. 19765-19771
    • Klebanoff, S.J.1    Waltersdorph, A.M.2    Michel, B.R.3    Rosen, H.4
  • 43
    • 0026770143 scopus 로고
    • Transferrin-receptor-independent but iron-dependent proliferation of variant Chinese hamster ovary cells
    • Chan RYY, Ponka P and Schulman HM, Transferrin-receptor-independent but iron-dependent proliferation of variant Chinese hamster ovary cells. Exp Cell Res 202: 326-336, 1992.
    • (1992) Exp Cell Res , vol.202 , pp. 326-336
    • Chan, R.Y.Y.1    Ponka, P.2    Schulman, H.M.3
  • 44
    • 0027447936 scopus 로고
    • The in vitro response of human tumour cells to desferrioxamine is growth medium dependent
    • Voest EE, Rooth H, Neijit JP, van Asbeck BS and Marx JJM, The in vitro response of human tumour cells to desferrioxamine is growth medium dependent. Cell Prolif 26: 77-88, 1993.
    • (1993) Cell Prolif , vol.26 , pp. 77-88
    • Voest, E.E.1    Rooth, H.2    Neijit, J.P.3    Van Asbeck, B.S.4    Marx, J.J.M.5
  • 45
    • 0022978272 scopus 로고
    • Effect of antioxidants on primary alloantigen-induced T cell activation and proliferation
    • Chaudhri G, Clark IA, Hunt NH, Cowden WB and Ceredig R, Effect of antioxidants on primary alloantigen-induced T cell activation and proliferation. J Immunol 137: 2646-2656, 1986.
    • (1986) J Immunol , vol.137 , pp. 2646-2656
    • Chaudhri, G.1    Clark, I.A.2    Hunt, N.H.3    Cowden, W.B.4    Ceredig, R.5
  • 46
    • 0023740171 scopus 로고
    • Antioxidants inhibit proliferation and cell surface expression of receptors for interleukin-2 and transferrin in T lymphocytes stimulated with phorbol myristate and ionomycin
    • Chaudhri G, Hunt NH, Clark IA and Ceredig R, Antioxidants inhibit proliferation and cell surface expression of receptors for interleukin-2 and transferrin in T lymphocytes stimulated with phorbol myristate and ionomycin. Cell Immunol 115: 204-213, 1988.
    • (1988) Cell Immunol , vol.115 , pp. 204-213
    • Chaudhri, G.1    Hunt, N.H.2    Clark, I.A.3    Ceredig, R.4
  • 47
    • 0026513803 scopus 로고
    • Effects of anti-oxidants on ornithine decarboxylase in mitogenically-activated T lymphocytes
    • Hunt NH and Fragonas J-C, Effects of anti-oxidants on ornithine decarboxylase in mitogenically-activated T lymphocytes. Biochim Biophys Acta 1133: 261-267, 1992.
    • (1992) Biochim Biophys Acta , vol.1133 , pp. 261-267
    • Hunt, N.H.1    Fragonas, J.-C.2
  • 48
    • 0025022631 scopus 로고
    • Delivery of iron to human cells by bovine transferrin
    • Young SP and Garner C, Delivery of iron to human cells by bovine transferrin. Biochem J 265: 587-591, 1990.
    • (1990) Biochem J , vol.265 , pp. 587-591
    • Young, S.P.1    Garner, C.2
  • 49
    • 0026701955 scopus 로고
    • Inhibition of hematopoietic tumor growth by combined treatment with deferoxamine and an IgG monoclonal antibody against the transferrin receptor: Evidence for a threshold model of iron deprivation toxicity
    • Kemp JD, Thorson JA, Stewart BC and Naumann PW, Inhibition of hematopoietic tumor growth by combined treatment with deferoxamine and an IgG monoclonal antibody against the transferrin receptor: Evidence for a threshold model of iron deprivation toxicity. Cancer Res 52: 4144-4148, 1992.
    • (1992) Cancer Res , vol.52 , pp. 4144-4148
    • Kemp, J.D.1    Thorson, J.A.2    Stewart, B.C.3    Naumann, P.W.4
  • 50
    • 0025125020 scopus 로고
    • Synergistic inhibition of lymphoid tumor growth in vitro by combined treatment with the iron chelator deferoxamine and an immunoglobulin G monoclonal antibody against the transferrin receptor
    • Kemp JD, Smith KM, Kanner LJ, Gomez F, Thorson JA and Naumann PW, Synergistic inhibition of lymphoid tumor growth in vitro by combined treatment with the iron chelator deferoxamine and an immunoglobulin G monoclonal antibody against the transferrin receptor. Blood 76: 991-995, 1990.
    • (1990) Blood , vol.76 , pp. 991-995
    • Kemp, J.D.1    Smith, K.M.2    Kanner, L.J.3    Gomez, F.4    Thorson, J.A.5    Naumann, P.W.6
  • 53
    • 0023621784 scopus 로고
    • Serial studies of auditory neurotoxicity in patients receiving deferoxamine therapy
    • Gallant T, Boyden MH, Gallant LA, Carley H and Freedman MH, Serial studies of auditory neurotoxicity in patients receiving deferoxamine therapy. Am J Med 83: 1085-1090, 1987.
    • (1987) Am J Med , vol.83 , pp. 1085-1090
    • Gallant, T.1    Boyden, M.H.2    Gallant, L.A.3    Carley, H.4    Freedman, M.H.5


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