Changes in bone mass during low dose corticosteroid treatment in patients with polymyalgia rheumatica: A double blind, prospective comparison between prednisolone and deflazacort

Annals of the Rheumatic Diseases

Volumn 55, Issue 2, 1996, Pages 143-146

  Krogsgaard, Michael R ^a,d   Thamsborg, Gorm ^b   Lund, Birger ^c  

^a Department of Internal Medicine   (Denmark)

^b Copenhagen Municipal Hospital ^*  (Denmark)

^c Geriatric Rehabilitation Centre   (Denmark)

^d Rigshospitalet   (Denmark)

Author keywords

[No Author keywords available]

Indexed keywords

DEFLAZACORT; PREDNISOLONE;

AGED; ARTICLE; BONE ATROPHY; BONE MINERAL; CLINICAL ARTICLE; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DOUBLE BLIND PROCEDURE; FEMALE; HUMAN; MALE; ORAL DRUG ADMINISTRATION; PHOTON ABSORPTIOMETRY; PRIORITY JOURNAL; RHEUMATIC POLYMYALGIA;

EID: 0030063712     PISSN: 00034967     EISSN: None     Source Type: Journal    
DOI: 10.1136/ard.55.2.143     Document Type: Article

References (15)

1. Adinoff A D, Hollister J R. Steroid induced fractures and bone loss in patients with asthma. N Engl J Med 1983; 309: 265-8.
2. Dykman T R, Gluck O S, Murphy W A, Hahn T J, Hahn B H. Evaluation of factors associated with glucocorticoid-induced osteopenia in patients with rheumatic disease. Arthritis Rheum 1985; 28: 361-8.
3. Reid D M, Kennedy N S J, Smith M A, et al. Bone loss in rheumatoid arthritis and primary generalised osteoarthrosis: effects of corticosteroids, suppressive anti-rheumatic drugs and calcium supplements. Br J Rheumatol 1986; 25: 253-9.
4. Sambrook P N, Eisman J A, Champion G D, Yeates M G, Pocock N A, Eberl S. Determinants of axial bone loss in rheumatoid arthritis. Arthritis Rheum 1987; 30; 721-8.
5. Olgaard K, Storm T, Wowern N V, et al. Glucocorticoid-induced osteoporosis in the lumbar spine, forearm, and mandible of nephrotic patients: a double-blind study on the high-dose, long-term effects of prednisone versus deflazacon. Calcif Tissue Int 1992; 50: 490-7.
6. Sambrook P N, Eisman J A, Yeates M G, Pocock N A, Eberl S, Champion G D. Osteoporosis in rheumatoid arthritis: safety of low dose corticosteroids. Ann Rheum Dis 1986; 45: 950-3.
7. Loftus J K, Reeve J, Hesp R, David J, Ansell B M, Woo P M M. Deflazacort in juvenile chronic arthritis. J Rheumatol 1993; 20: 40-2.
8. Bird H A, Esselintk W, Dixon A St J, Mowat A G, Wood P H N. An evaluation of criteria for polymyalgia rheumatica. Ann Rheum Dis 1979; 38: 434-9.
9. Messina O D, Barreira J C, Zanchetta J R, et al. Effect of low doses of deflazacort vs prednisonc on bone mineral content in premenopausal rheumatoid arthritis. J Rheumatol 1992; 19: 1520-6.
10. Gray R E S, Doherty S M, Galloway J, Coulton L, de Broe M, Kanis J A. A double-blind study of deflazacort and prednisolone in patients with chronic inflammatory disorders. Arthritis Rheum 1991; 34: 287-95.
11. Lund B, Egsmose C, Jørgensen S, Krogsgaard M R. Establishment of the relative antiinflammatory potency of deflazacort and prednisone in polymyalgia rheumatica. Calcif Tissue Int 1987; 41: 316-20.
12. Krølner B, Toft B. Vertebral bone loss: an unheeded side effect of therapeutic bed rest. Clin Aci 1983; 64: 537-40.
13. Pacifici R, Susman N, Carr P L, Birge S J, Avioli L V. Single and dual energy tomographic analysis of spinal trabecular bone: a comparative study in normal and osteoporotic women. J Clin Endocrinol Metab 1987; 64: 209-14.
14. Thamsborg G, Storm T L, Sørensen O H. Serial changes in forearm and lumbar bone mineral content (BMC) during treatment with glucocorticoids in patients with giant cell arteritis. Calcif Tissue Int 1986; 39 (suppl): A108.
15. Gennari C, Imbimbo B. Effects of prednisone and deflazacort on vertebral bone mass. Calcif Tissue Int 1985; 37: 592-3.