Sp1 is critical for basal and E2-transactivated transcription from the bovine papillomavirus type 1 P89 promoter

Journal of General Virology

Volumn 77, Issue 2, 1996, Pages 189-198

  Sandler, Abby B ^a,b   Baker, Carl C ^a   Spalholz, Barbara A ^a  

^a NATIONAL CANCER INSTITUTE   (United States)

^b Pro Neuron Inc   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CHLORAMPHENICOL ACETYLTRANSFERASE; TRANSCRIPTION FACTOR SP1;

ARTICLE; BINDING SITE; CONSENSUS SEQUENCE; CONTROLLED STUDY; EXPRESSION VECTOR; GENE EXPRESSION REGULATION; GENE MUTATION; NONHUMAN; NUCLEOTIDE SEQUENCE; PAPILLOMA VIRUS; PRIORITY JOURNAL; PROMOTER REGION; TRANSACTIVATION; TRANSCRIPTION REGULATION;

BOVINAE; BOVINE PAPILLOMAVIRUS; BOVINE PAPILLOMAVIRUS TYPE 1; BOVINE PARVOVIRUS; FELIS CATUS; PAPILLOMAVIRUS;

EID: 0030063608     PISSN: 00221317     EISSN: None     Source Type: Journal    
DOI: 10.1099/0022-1317-77-2-189     Document Type: Article

References (40)

1. AHOLA, H., STENLUND, A , MORENO-LOPEZ, J. & PETTERSSON, U (1987). Promoters and processing sites within the transforming region of bovine papillomavirus type 1 Journal of Virology 61, 2240-2244.
2. ANDROPHY, E. J , LOWY, D. R. & SCHILLER, J. T. (1987). A peptide encoded by the bovine papillomavirus E2 trans-acting gene binds to specific sites in papillomavirus DNA. Nature 325, 70-73.
3. BAKER, C. C. (1990). Bovine papillomavirus transcription. In Papillomaviruses and Human Cancer, pp 91-112. Edited by H. Pfister. Boca Raton, Fla.: CRC Press.
4. BLITZ, I. L. & LAIMINS, L. (1991). The 68-kilodalton E1 protein of bovine papillomavirus is a DNA binding phosphoprotein which associates with the E2 transcriptional activator in vitro. Journal of Virology 65, 649-656.
5. CHAN, W. K., CHONG, T., BERNARD, U. & KLOCK, G. (1990). Transcription of the transforming genes of the oncogenic human papillomavirus-16 is stimulated by tumor promoters through AP1 binding sites. Nucleic Acids Research 18, 763-769.
6. CHONG, T., CHAN, W. K. & BERNARD, H. U. (1990). Transcriptional activation of human papillomavirus 16 by nuclear factor 1, AP1, steroid receptors and a possibly novel transcription factor, PVF: a model for the composition of genital papillomavirus enhancers Nucleic Acids Research 18, 465-470.
7. DIGNAM, J. D., LEBOVITZ, R. M. & ROEDER, R. G. (1983). Accurate transcription initiation by RNA polymerase II in a soluble extract from isolated mammalian nuclei. Nucleic Acids Research 11, 1475-1489.
8. DOSTATNI, N , THIERRY, F. & YANIV, M. (1988). A dimer of BPV-1 E2 protein containing a protease resistant core interacts with its DNA target EMBO Journal 7, 3807-3816.
9. DOSTATNI, N., LAMBERT, P. F , SOUSA, R., HAM, J., HOWLEY, P M. & YANIV, M (1991). The functional BPV-1 E2 trans-activating protein can act as a repressor by preventing formation of the initiation complex. Genes & Development 5, 1657-1671.
10. GLOSS, B. & BERNARD, H. U. (1990). The E6/E7 promoter of human papillomavirus type 16 is activated in the absence of E2 proteins by a sequence-aberrant Sp1 distal element. Journal of Virology 64, 5577-5584.
11. GLOSS, B., YEO-GLOSS, M., MEISTERERNST, M., ROGGE, L., WINNACKER, E. L. & BERNARD, H. U. (1989). Clusters of nuclear factor I binding sites identify enhancers of several papillomaviruses but alone are not sufficient for enhancer function. Nucleic Acids Research 17, 3519-3533.
12. GRAHAM, F. L. & VAN DER EB, A J (1973). A new technique for the assay of infectivity of human adenovirus 5 DNA. Virology 52, 456-461.
13. HAM, J., DOSTATNI, N., ARNOS, F. & YANIV, M. (1991) Several different upstream promoter elements can potentiate transactivation by the BPV-1 E2 protein EMBO Journal 10, 2931-2940.
14. HOPPE-SEYLER, F. & BUTZ, K. (1992) Activation of human papilloma-virus type 18 E6-E7 oncogene expression by transcription factor Sp1. Nucleic Acids Research 20, 6701-6706.
15. LAMBERT, P. F. & HOWLEY, P M. (1988). Bovine papillomavirus type 1 E1 replication-defective mutants are altered in their transcriptional regulation. Journal of Virology 62, 4009-4015.
16. Li, R., KNIGHT, J., BREAM, G., STENLUND, A. & BOTCHAN, M. (1989). Specific recognition nucleotides and their DNA context determine the affinity of E2 protein for 17 binding sites in the BPV-1 genome. Genes & Development 3, 510-526.
17. Li, R., KNIGHT, J. D., JACKSON, S. P., TJIAN, R. & BOTCHAN, M. R. (1991). Direct interaction between Sp1 and the BPV enhancer E2 protein mediates synergistic activation of transcription. Cell 65, 493-505
18. MCBRIDE, A. A., BYRNE, J. C. & HOWLEY, P. M. (1989). E2 polypeptides encoded by bovine papillomavirus I form dimers through the carboxy-terminal DNA-binding domain, transactivation is mediated through the amino-terminal domain. Proceedings of the National Academy of Sciences, USA 86, 510-514.
19. MOHR, I. J., CLARK, R., SUN, S , ANDROPHY, E J., MACPHERSON, P. & BOTCHAN, M. (1990). Targeting the E1 replication protein to the papillomavirus origin of replication by complex formation with the E2 transactivator. Science 250, 1694-1699.
20. NEARY, K & DIMAIO, D. (1989) Open reading frames E6 and E7 of bovine papillomavirus type 1 are both required for full transformation of mouse C127 cells. Journal of Virology 63, 259-266.
21. ROMANCZUK, H. & HOWLEY, P. M (1992) Disruption of either the E1 or E2 regulatory gene of human papillomavirus type 16 increases viral immortalization capacity. Proceedings of the National Academy of Sciences, USA 89, 3159-3163.
22. SANDLER, A. B., VANDE POL, S. B. & SPALHOLZ, B. A. (1993). Repression of bovine papillomavirus type 1 transcription by the E1 replication protein. Journal of Virology 67, 5079-5087.
23. SCHILLER, J. T., KLEINER, E., ANDROPHY, E. J., LOWY, D. R. & PFISTER, H. (1989). Identification of bovine papillomavirus E1 mutants with increased transforming and transcriptional activity. Journal of Virology 63, 1775-1782.
24. SCHILLER, J. T., VASS, W. C. & LOWY, D. R. (1984). Identification of a second transforming region in bovine papillomavirus DNA. Proceedings of the National Academy of Sciences, USA 81, 7880-7884.
25. SEO, Y. S., MÜLLER, F., LUSKY, M., GIBBS, E., KIM, H. Y., PHILLIPS, B. & HURWITZ, J. (1993). Bovine papillomavirus (BPV)-encoded E2 protein enhances binding of E1 protein to the BPV replication origin. Proceedings of the National Academy of Sciences, USA 90, 2865-2869
26. SPALHOLZ, B. A., YANG, Y. C & HOWLEY, P. M. (1985). Transactivation of a bovine papillomavirus transcriptional regulatory element by the E2 gene product. Cell 42, 183-191.
27. SPALHOLZ, B. A., LAMBERT, P. F., YEE, C. L. & HOWLEY, P. M. (1987). Bovine papillomavirus transcriptional regulation: localization of the E2-responsive elements of the long control region. Journal of Virology 61, 2128-2137.
28. SPALHOLZ, B. A., VANDE POL, S. B. & HOWLEY, P. M. (1991). Characterization of the cis elements involved in basal and E2-transactivated expression of the bovine papillomavirus P2443 promoter. Journal of Virology 65, 743-753
29. SPALHOLZ, B A., MCBRIDE, A. A., SARAFI, T. & QUINTERO, J. (1993). Binding of bovine papillomavirus E1 to the origin is not sufficient for DNA replication. Virology 193, 201-212.
30. STENLUND, A., ZABIELSKI, J., AHOLA, H., MORENO-LOPEZ, J. & PETTERSSON, U. (1985). Messenger RNAs from the transforming region of bovine papillomavirus type 1. Journal of Molecular Biology 182, 541-554.
31. SZYMANSKI, P. & STENLUND, A. (1991). Regulation of early gene expression from the bovine papillomavirus genome in transiently transfected C127 cells. Journal of Virology 65, 5710-5720.
32. TOMIC, M., SUNJEVARIC, I., SAVTCHENKO, E. S. & BLUMENBERG, M. (1990). A rapid and simple method for introducing specific mutations into any position of DNA leaving all other positions unaltered. Nucleic Acids Research 18, 1656.
33. USTAV, M., USTAV, E., SZYMANSKI, P. & STENLUND, A. (1991). Identification of the origin of replication of bovine papillomavirus and characterization of the viral origin recognition factor E1. EMBO Journal 10, 4321-4329.
34. USTAV, E., USTAV, M., SZYMANSKI, P. & STENLUND, A. (1993). The bovine papillomavirus origin of replication requires a binding site for the E2 transcriptional activator. Proceedings of the National Academy of Sciences, USA 90, 898-902.
35. VANDE POL, S. B. & HOWLEY, P. M. (1990) A bovine papillomavirus constitutive enhancer is negatively regulated by the E2 repressor through competitive binding for a cellular factor. Journal of Virology 64, 5420-5429.
36. VANDE POL, S B. & HOWLEY, P. M. (1992). The bovine papillomavirus constitutive enhancer is essential for viral transformation. DNA replication, and the maintenance of latency. Journal of Virology 66, 2346-2358
37. WILSON, V. & LUDES-MEYERS, J. (1991). A bovine papillomavirus E1-related protein binds specifically to bovine papiliomavirus DNA. Journal of Virology 65, 5314-5322.
38. WINOKUR, P. & MCBRIDE, A. A (1992). Separation of the transcriptional activation and replication functions of the bovine papillomavirus-1 E2 protein. EMBO Journal 11, 4111-4118.
39. YANG, Y. C., OKAYAMA, H. & HOWLEY, P. M. (1985). Bovine papillomavirus contains multiple transforming genes. Proceedings of the National Academy of Sciences, USA 82, 1030-1034.
40. YANG, L., Li, R., MOHR, I. J., CLARK, R. & BOTCHAN, M. (1991). Activation of BPV-1 replication in vitro by the transcription factor E2. Nature 353, 628-632.