Differential effects of pre-treatment with intrathecal or intravenous morphine on the prevention of spinal cord hyperexcitability following sciatic nerve section in the rat

Acta Anaesthesiologica Scandinavica

Volumn 40, Issue 1, 1996, Pages 91-95

  Luo, L ^a   Wiesenfeld Hallin, Z ^a  

^a KAROLINSKA UNIVERSITY HOSPITAL   (Sweden)

Author keywords

Hyperalgesia; Opioids; Postoperative pain; Preemptive analgesia

Indexed keywords

MORPHINE; NALOXONE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CONTROLLED STUDY; DRUG EFFECT; FEMALE; HYPERALGESIA; INTRATHECAL DRUG ADMINISTRATION; INTRAVENOUS DRUG ADMINISTRATION; NERVE TRANSECTION; NONHUMAN; POSTOPERATIVE PAIN; PRIORITY JOURNAL; RAT; SCIATIC NERVE; SPINAL CORD;

EID: 0030063330     PISSN: 00015172     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1399-6576.1996.tb04393.x     Document Type: Article

References (15)

1. Woolf CJ, Chong M-S. Preemptive analgesia-treating post-operative pain by preventing the establishment of central sensitization. Anesth Analg 1993: 77: 362-379.
2. Wall PD, Waxman S, Basbaum A. Ongoing activity in peripheral nerve: Injury discharge. Exp Neurol 1974: 45: 576-588.
3. Wall PD, Woolf CJ. Muscle but not cutaneous C-afferent input produces prolonged increases in the excitability of the flexion reflex in the rat. J Physiol (London) 1984: 356: 443-458.
4. McMahon SB, Wall PD. Changes in spinal cord reflexes after cross-anastomosis of cutaneous and muscle nerves in the adult rat. Nature 1989: 342: 272-274.
5. McQuar HJ, Carroll D, Moore RA. Postoperative orthopaedic pain - the effect of opiate premedication and local anaesthetic blocks. Pain 1988: 33: 291-295.
6. Richmond CE, Bromley LM, Woolf CJ. Preoperative morphine pre-empts postoperative pain. The Lancet 1993: 342: 73-75.
7. Katz J, Kavanagh BP, Sandler AN, Nierenberg H, Boylan JF, Friedlander M, et al. Pre-emptive analgesia: clinical evidence of neuroplasticity contributing to postoperative pain. Anesthesiology 1992: 77: 439-446.
8. Bach S, Noreng MF, Tjéllden NU. Phantom limb pain in amputees during the first 12 months following limb amputation, after preoperative lumbar epidural blockade. Pain 1988: 33: 297-301.
9. Tverskoy M, Oz Y, Isakson A, Finger J, Bradley Jr. EL, Kissin I. Preemptive effect of fentanyl and ketamine on postoperative pain and wound hyperalgesia. Anesth Analg 1994: 78: 205-209.
10. Luo L, Puke MJC, Wiesenfeld-Hallin Z. The effects of intrathecal morphine and clonidine on the prevention and reversal of spinal cord hyperexcitability following sciatic nerve section in the rat. Pain 1994: 58: 245-252.
11. 2-adrenoceptor agonists clonidine and dexmedetomidine on the prevention and treatment of experimental neuropathic pain. Anesth Analg 1993: 77: 104-109.
12. Hökfelt T, Zhang X, Wiesenfeld-Hallin Z. Messenger plasticity in primary sensory neurons following axotomy and its functional implications. Trends Neurosci 1994: 17: 22-29.
13. Wiesenfeld-Hallin Z, Xu X-J, Håkanson R, Feng D-M, Folkers K. The specific antagonistic effect of intrathecal spantide II on substance P- and C-fiber conditioning stimulation-induced facilitation of the nociceptive flexor reflex in rats. Brain Res 1990: 526: 284-290.
14. Dickenson AH. Where and how do opioids act? In: Gebhart AG, Hammond DL, Jensen TS, eds. Progress in pain research and management, vol 2, Proceedings of the 7th world congress on pain, Seattle: IASP Press, 1994: 525-552.
15. Morgan M. The rational use of intrathecal and extradural opioids. Br J Anaesth 1989: 63: 165-188.