Effects of upper airway stimulation on swallowing, gasping, and autoresuscitation in hypoxic mice

Journal of Applied Physiology

Volumn 80, Issue 2, 1996, Pages 472-477

  Khurana, Atul ^a,b   Thach, Bradley T ^a  

^a WASHINGTON UNIVERSITY   (United States)

^b WASHINGTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

apnea; aspiration; chemoreflex; larynx; obstruction; sudden death

Indexed keywords

AIRWAY OBSTRUCTION; ANIMAL EXPERIMENT; APNEA; ARTICLE; CONTROLLED STUDY; HYPOXIA; LUNG ASPIRATION; MECHANICAL STIMULATION; MOUSE; NONHUMAN; PRIORITY JOURNAL; RESUSCITATION; SWALLOWING;

EID: 0030063227     PISSN: 87507587     EISSN: None     Source Type: Journal    
DOI: 10.1152/jappl.1996.80.2.472     Document Type: Article

References (43)

1. Abu-Osba, Y. K., O. P. Mathew, and B. T. Thach. An animal model for airway sensory deprivation producing obstructive apnea with postmortem findings of sudden infant death syndrome. Pediatrics 68: 796-801, 1981.
2. Adolph, E. F., and P. A. Hoy. Ventilation of lungs in infant and adult rats and its responses to hypoxia. J. Appl. Physiol. 15: 1075-1086, 1960.
3. Am. Vet. Med. Assoc. Report of the AVMA panel on euthanasia J. Am. Vet. Med. Assoc. 173: 59-72, 1978.
4. Boggs, D. F., and D. Bartlett, Jr. Chemical specificity of a laryngeal apneic reflex in puppies. J. Appl. Physiol. 53: 455-462, 1982.
5. Davies, A. M., J. S. Koenig, and B. T. Thach. Upper airway chemoreflex responses to saline and water in preterm infants. J. Appl. Physiol. 64:1412-1420, 1988.
6. Dehaan, R., and J. Field. Anoxic endurance of cardiac and respiratory function in the adult and infant rat. Am. J. Physiol. 197: 445-448, 1959.
7. Donnelly, D. F., and G. G. Haddad. Effect of graded anaesthesia on laryngeal-induced central apnea. Respir. Physiol. 66: 235-245, 1986.
8. Downing, S. E., and J. C. Lee. Laryngeal chemosensitivity: a possible mechanism for sudden infant death. Pediatrics 55: 640-649, 1975.
9. Enzmann, E. V., and G. Pincus. The extinction of reflexes in spinal mice of different ages as an indicator of the decline of anaerobiosis. J. Gen. Physiol. 18: 163-169, 1934.
10. Fazekas, J. F., F. A. D. Alexander, and H. E. Himwich. Tolerance of the newborn to anoxia. Am. J. Physiol. 134: 281-287, 1941.
11. Gershan, W. M., M. S. Jacobi, and B. T. Thach. Maturation of cardiorespiratory interactions in spontaneous recovery from hypoxic apnea (autoresuscitation). Pediatr. Res. 28: 87-93, 1990.
12. Gershan, W. M., M. S. Jacobi, and B. T. Thach. Mechanisms underlying induced autoresuscitation failure in BALB/c and SWR mice. J. Appl. Physiol. 72: 677-685, 1992.
13. Godfrey, S. Respiratory and cardiovascular changes during asphyxia and resuscitation of foetal and newborn rabbits. Q. J. Exp. Physiol. 53: 97-118, 1968.
14. Goding, G. S., M. A. Richardson, and R. E. Trachy. Laryngeal chemoreflex: anatomic and physiologic study by use of the superior laryngeal nerve in the piglet. Otolaryngol. Head Neck Surg. 97: 28-38, 1987.
15. Guntheroth, W. G., and I. Kawabori. Hypoxic apnea and gasping. J. Clin. Invest. 56: 1371-1377, 1975.
16. Harding, R., P. Johnson, and M. E. McClelland. Liquid-sensitive laryngeal receptors in the developing sheep, cat and monkey. J. Physiol. Lond. 277: 409-422, 1978.
17. Jacobi, M. S., W. M. Gershan, and B. T. Thach. Effect of pentobarbital on spontaneous recovery from hypoxic apnoea in mice. Respir. Physiol. 84: 337-349, 1991.
18. Jacobi, M. S., W. M. Gershan, and B. T. Thach. Mechanism of failure of recovery from hypoxic apnea by gasping in 17-to 23-day-old mice. J. Appl. Physiol. 71: 1098-1105, 1991.
19. Jacobi, M. S., and B. T. Thach. Effect of maturation on spontaneous recovery from hypoxic apnea by gasping. J. Appl. Physiol. 66: 2384-2390, 1989.
20. Johnson, P., D. M. Salisbury, and A. T. Storey. Apnoea induced by stimulation of sensory receptors in the larynx. In: Symposium on Development of Upper Respiratory Anatomy and Function, edited by J. F. Bosma and J. Showacre. Washington, DC: US Govt. Printing Office, 1975, p. 160-183.
21. Kabat, H., and C. Dennis. Resistance of young dogs to acute arrest of the cephalic circulation. Proc. Soc. Exp. Biol. Med. 42: 534-537, 1939.
22. Kessler, M., H. Hailman, and E. Gellhorn. Studies on the effect of anoxic anoxia on the central nervous system. Am. J. Physiol. 140: 291-298, 1943.
23. Khurana, A., and B. T. Thach. Importance of airway protective reflexes in autoresuscitation from prolonged apnea (Abstract). Pediatr. Res. 33: 332A, 1993.
24. Lanier, B., M. A. Richardson, and C. Cummings. Effect of hypoxia on laryngeal reflex apnea - implications for sudden infant death. Otolaryngol. Head Neck Surg. 91: 597-604, 1983.
25. Melton, J. E., L. O. Chae, and N. H. Edelman. Effects of respiratory afferent stimulation on phrenic neurogram during hypoxic gasping in the cat. J. Appl. Physiol. 75: 2091-2098, 1993.
26. National Institute of Health. Guide for the Care and Use of Laboratory Animals. Bethesda, MD: Natl. Inst. Health, 1985, p. 38. (DHEW Publ. NIH-86-23.)
27. Nishino, T., T. Kohchi, Y. Honda, M. Shirahata, and T. Yonezawa. Differences in the effects of hypercapnia and hypoxia on the swallowing reflex in cats. Br. J. Anaesth. 58: 903-908, 1986.
28. Noell, W., and H. I. Chinn. Failure of the visual pathway during anoxia. Am. J. Physiol. 161: 573-590, 1950.
29. Peiper, A. Gasping respiration. In: Cerebral Function in Infancy and Childhood. New York: Consultants Bureau, 1963, p. 327-339.
30. Perkett, E. A., and R. L. Vaughan. Evidence for a laryngeal chemoreflex in some human preterm infants. Acta Paediatr. Scand. 71: 969-972, 1982.
31. Selle, W. A. Influence of age on survival of respiration, spinal reflexes, pupillary responses and heart action. Proc. Soc. Exp. Biol. Med. 48: 417-419, 1941.
32. Simpson, K. Pathology of sudden death. Lancet. 2: 745-747, 1947.
33. St. John, W. M. Neurogenesis, control and functional significance of gasping. J. Appl. Physiol. 68: 1305-1315, 1990.
34. St. John, W. M., and K. V. Knuth. A characterization of the respiratory pattern of gasping. J. Appl. Physiol. 50: 984-993, 1981.
35. Stephen, C. R., E. W. Ahlgren, and E. J. Bennett. Physiologic background. In: Elements of Pediatric Anesthesia. Springfield, IL: Thomas, 1970, p. 5-24.
36. Stevens, M. H. Sudden unexplained death in infancy. Am. J. Dis. Child. 110: 243-247, 1965.
37. Thach, B. T., M. S. Jacobi, and W. M. Gershan. Control of breathing during asphyxia and autoresuscitation. In: Developmental Neurobiology of Breathing, edited by G. G. Haddad and J. P. Farber. New York: Dekker, 1991, vol. 52, p. 681-699. (Lung Biol Health Dis. Ser.)
38. Tomori, Z., R. Benacka, V. Donic, and R. Tkacova. Reversal of apnoea by aspiration reflex in anaesthetized cats. Eur. Respir. J. 4: 1117-1125, 1991.
39. Tomori, Z., V. Donic, and M. Kurpas. Comparison of inspiratory effort in sniff-like aspiration reflex, gasping and normal breathing in cats. Eur. Respir. J. 6: 53-59, 1993.
40. Valdes-DaPena, M. A. Sudden and unexpected death in infancy: a review of the world literature 1954-1966. Pediatrics 39: 123-138, 1967.
41. Wennergren, G., T. Hertzberg, J. Milerad, J. Bjure, and H. Lagercrantz. Hypoxia reinforces laryngeal reflex bradycardia in infants. Acta Paediatr. Scand. 78. 11-17, 1989.
42. Werne, J., and I. Garrow. Sudden apparently unexplained death during infancy. I. Pathologic findings in infants found dead. Arch. Pathol. 29: 633-675, 1953.
43. Woolley, S. C., and M. J. Gentle. Physiological and behavioral responses of the domestic hen to hypoxia. Res. Vet. Sci. 45: 377-382, 1988.