A mannose 6-phosphate-containing N-linked glycopeptide derived from lysosomal acid lipase is bound to mhc class II in B lymphoblastoid cell lines

Journal of Immunology

Volumn 156, Issue 5, 1996, Pages 1841-1847

  Dustin, Michael L ^a   McCourt, Dave W ^a,b   Kornfeld, Stuart ^a  

^a WASHINGTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b Midwest Analytical   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ACID LIPASE; GLYCOPEPTIDE; MAJOR HISTOCOMPATIBILITY ANTIGEN CLASS 2; MANNOSE 6 PHOSPHATE;

ALLELE; ANTIBODY AFFINITY; ANTIGEN BINDING; ARTICLE; B LYMPHOBLAST; HUMAN; HUMAN CELL; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN DETERMINATION; PROTEIN LOCALIZATION; RECEPTOR AFFINITY; SEQUENCE ANALYSIS;

AMINO ACID SEQUENCE; B-LYMPHOCYTES; CARBOHYDRATE CONFORMATION; CELL LINE; GLYCOPEPTIDES; HLA-DR ANTIGENS; HUMANS; LIPASE; LYMPHOCYTE ACTIVATION; LYSOSOMES; MANNOSEPHOSPHATES; MEMBRANE GLYCOPROTEINS; MOLECULAR SEQUENCE DATA; PEPTIDES; PROTEIN BINDING; RECEPTOR, IGF TYPE 2;

EID: 0030063185     PISSN: 00221767     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (54)

1. Unanue, E. R 1984 Antigen-presenting function of the macrophage. Annu. Rev. Immunol. 2:395.
2. Germain, R N., and D. H. Margulies. 1993 The biochemistry and cell biology of antigen processing and presentation Annu. Rev. Immunol. 11:403.
3. Cresswell, P. 1994. Assembly, transport, and function of MHC class II molecules. Annu. Rev. Immunol. 12:259
4. Engelhard, V H 1994 Structure of peptides associated with class I and class II MHC molecules. Annu. Rev. Immunol. 12:181.
5. Matzinger, P. 1994. Tolerance, danger, and the extended family Annu Rev Immunol. 12:991.
6. Rudensky, A Y., P Preston-Hurlburt, S. C. Hong, A. Barlow, and C A Janeway, Jr. 1991. Sequence analysis of peptides bound to MHC class II molecules. Nature 353:622.
7. Nelson, C. A., R. W. Roof, D. W. McCourt, and E. R. Unanue. 1992. Identification of the naturally processed form of hen egg white lysosyme bound to the murine major histocompatibility complex class II molecule I-Ak. Proc. Natl. Acad. Sci. USA 89:7380.
8. Chicz, R M., R. G. Urban, W. S Lane, J. C. Gorga, L. J. Stern, D A. A. Vignali, and J L. Strominger. 1992. Predominant naturally processed peptides bound to HLA-DR1 are derived from MHC-retated molecules and are heterogeneous in size. Nature 358:764
9. Hunt, D. F., H. Michel, T A. Dickinson, J Shabanowitz, A. L. Cox, K. Sakaguchi, E Appella, H. M. Grey, and A. Sette 1992 Peptides presented to the immune system by the murine class II major histocompatibility complex molecule I-Ad. Science 256:1817
10. Newcomb, J. R., and P. Cresswell. 1993. Characterization of endogenous peptides bound to purified HLA-DR molecules and their absence from invariant chain-associated αβ dimers J Immunol. 150:499.
11. Chicz, R. M., R. G Urban, J. C. Gorga, D. A. A. Vignali, W. S. Lane, and J. L. Strominger. 1993 Specificity and promiscuity among naturally processed peptides bound to HLA-DR alleles. J. Exp. Med. 178:27.
12. Ishioka, G. Y , A. G. Lamont, D. Thomson, N. Bulbow, F. C. Gaeta, A. Sette, and H. M Grey. 1992. MHC interaction and T cell recognition of carbohydrates and glycopeptides. J Immunol. 148:2446.
13. Nalefski, E. A., and A. Rao. 1993. Nature of the ligand recognized by a hapten-and carrier-specific, MHC-restricted T cell receptor. J. Immunol. 150:3806
14. Harding, C. V., J. Kihlberg, M Elofsson, G. Magnusson, and E. R. Unanue. 1993. Glycopeptides bind MHC molecules and elicit specific T cell responses. J. Immunol. 151:2419.
15. Deck, B., M. Elofsson, J Kihlberg, and E. R. Unanue. 1995. Specificity of glycopeptide-specific T cells. J. Immunol. 155:1074
16. Guagliardi, L. E., B Koppelman, J S. Blum, M. S Marks, P Cresswell, and F. M. Brodsky. 1990 Co-localization of molecules involved in antigen processing and presentation in an early endocytic compartment. Nature 343.133.
17. Peters, P. J., J J. Neefjes, V. Oorschot, H. L. Ploegh, and H. J. Geuze. 1991. Segregation of MHC class II molecules from MHC class I molecules in the Golgi complex for transport to lysosomal compartments. Nature 349:669.
18. West, M. A., J. M. Lucocq, and C. Watts 1994. Antigen processing and class II MHC peptide-loading compartments in human B-lymphoblastoid cells. Nature 369 147.
19. Amigorena, S., J. R. Drake, P. Webster, and I. Mellman 1994 Transient accumulation of new class II MHC molecules in a novel endocytic compartment in B lymphocytes. Nature 369:113.
20. Tulp, A , D. Verwoerd, B. Dobberstein, H. L. Ploegh, and J. Pieters. 1994. Isolation and characterization of the intracellular MHC class II compartment Nature 369.120
21. Kornfeld, S., and I. Mellman. 1989 The biogenesis of lysosomes. Annu. Rev Cell Biol. 5:483.
22. Falk, K., O Rötzschke, S. Stevanovic, G. Jung, and H. G. Rammensee 1994 Pool sequencing of natural HLA-DR, DQ and DP ligands reveals detailed peptide motifs, constraints of processing, and general rules Immunogenetics 39.230.
23. Sahagian, G. G , J. J. Distler, and G W Jourdian. 1992. Membrane receptors for phosphomannosyl residues. Methods Enzymol. 83:392.
24. Simons, K , A Helenius, K. Leonard, M. Sarvas, and M. J. Gething. 1978. Formation of protein micelles from amphiphilic membrane proteins. Proc. Natl. Acad. Sci USA 75.5306.
25. Dustin, M. L , D. Olive, and T. A. Springer. 1989 Correlation of CD2 binding and functional properties of multimeric and monomeric lymphocyte function associated antigen-3. J. Exp. Med. 169:503
26. Fraker, P. J., and J C. Speck. 1978. Protein and cell membrane iodinations with a sparingly soluble chloroamide, 1,3,4,6-tetrachloro-3,6-diphenyl glycoluril. Biochem. Biophys Res. Commun. 80:849.
27. Baranski, T. J., P. L. Faust, and S. Kornfeld. 1990. Generation of a lysosomal enzyme targeting signal in the secretory protein pepsinogen Cell 63:281.
28. Hubbard, A L , and Z A. Cohn. 1972. The enzymatic iodination of the red cell membrane. J Cell Biol. 55:390.
29. Laemmli, U. K. 1970. Cleavage of structural proteins during the assembly of the head of bacteriophage T4. Nature 227:680.
30. Germain, R N., and L. R. Hendrix. 1991. MHC class II structure, occupancy and surface expression determined by post-endoplasmic reticulum antigen binding. Nature 353:134.
31. Cantor, A. B., T. J. Baranski, and S. Kornfeld. 1992. Lysosomal enzyme phosphorylation. II. Protein recognition determinants in either lobe of procathepsin D are sufficient for phosphorylation of both the amino and carboxyl lobe oligosaccharides J. Biol. Chem. 267:23349.
32. Varki, A. and S. Kornfeld. 1983. The spectrum of anionic oligosaccharides released by endo-beta-N-acetylglucosaminidase H from glycoproteins. J. Biol. Chem. 258:2808.
33. Cantor, A. B., and S. Kornfeld. 1992. Phosphorylation of asn-linked oligosaccharides located at novel sites on the lysosomal enzyme cathepsin D. J. Biol. Chem. 267:23357.
34. Jardetzky, T S , W. S. Lane, R. A. Robinson, D. R. Madden, and D. C. Wiley. 1991. Identification of self peptides bound to purified HLA-B27. Nature 353:326.
35. Kornfeld, R. and S. Kornfeld. 1985 Assembly of asparagine-linked oligosaccharides Annu Rev Biochem. 54.631.
36. Singer, K. H , S. M. Denning, L. P. Whichard, and B. F. Haynes. 1990. Thymocyte LFA-1 and thymic epithelial cell ICAM-1 molecules mediate binding of activated human thymocytes to thymic epithelial cells J Immunol. 144:2931.
37. Jones, P. P. 1984. Analysis of H-2 and Ia antigens by two-dimensional polyacrylamide gel electrophoresis. Methods Enzymol. 108:452.
38. Lamb, C. A , Y. W. Yewdell, J. R. Bennick, and P. Cresswell. 1991. Invariant chain targets HLA class II molecules to acidic endosomes containing influenza virus. Proc. Natl. Acad. Sci USA 88:5998
39. Teyton, L , and P. A. Peterson. 1992. Invariant chain-a regulator of antigen presentation Trends Cell Biol. 2:52.
40. Springer, T A., R J. Robb, C. Terhorst, and J. L. Strominger. 1977. Subunit and disulfide structure of monomeric and dimeric forms of detergent-soluble HLA antigens. J. Biol Chem 252:4694.
41. Sadegh-Nasseri, S , and R. N. Germain. 1991. A role for peptide in determining MHC class II structure Nature 353:167.
42. Nelson, C. A., S. J. Petzold, and E. R Unanue. 1994. Peptides determine the lifespan of MHC class II molecules in the antigen-presenting cell. Nature 371: 250.
43. Nelson, C. A , S. J Petzold, and E. R. Unanue. 1993. Identification of two distinct properties of class II major histocompatibility complex-associated peptides. Proc. Natl. Acad. Sci. USA 90:1227
44. Anderson, R. A., and G. N. Sando. 1991 Cloning and expression of cDNA encoding human lysosomal acid lipase/cholesteryl ester hydrolase. J. Biol. Chem. 266:22479
45. Ameis, D., M. Markel, D. C. Eckerskom, and H. Greten. 1994. Purification, characterization and molecular cloning of human hepatic lysosomal acid lipase. Eur J. Biochem 219:905.
46. Gieselmann, V., R Pohlmann, A. Hasilik, and K. von Figura. 1983. Biosynthesis and transport of cathepsin D in cultured human fibroblasts. J. Cell Biol. 97:1.
47. Einstein, R., and C. A. Gabel. 1991. Cell- and ligand-specific dephosphorylation of acid hydrolases: evidence that the mannose 6-phosphatase is controlled by compartmentalization J Cell Biol. 112:81.
48. Jardetzky, T. S., J. C. Gorga, R. Busch, J. Rothbard, J L. Strominger, and D. C. Wiley. 1990. Peptide binding to DR1: a peptide with most residues substituted to alanine retains MHC binding. EMBO J. 9:1797
49. Stern, L J., J. H. Brown, T S. Jardetzky, J. C. Gorga, R. G. Urban, J. L. Strominger, and D. C. Wiley. 1994 Crystal structure of the human class II MHC protein HLA-DR1 complexed with an influenza virus peptide. Nature 368:215.
50. Kageyama, S., T. J Tsomides, Y. Sykulev, and H. N. Eisen. 1995 Variations in the number of peptide-MHC class I complexes required to activate cytotoxic T cell responses. J. Immunol. 154:567
51. Harding, C. V . and E. R. Unanue. 1990. Quantitation of antigen-presenting cell MHC class II/peptide complexes necessary for T-cell stimulation Nature 346: 574.
52. Demotz, S , H. M. Grey, and A. Sette. 1990. The minimal number of class II MHC-antigen complexes needed for T cell activation. Science 249.1028.
53. Vignali, D. A. A., and J. L. Strominger. 1994. Amino acid residues that flank core peptide epitopes and the extracellular domains of CD4 modulate differential signalling through the T cell receptor. J. Exp. Med. 179:1945.
54. Bezouska, K., C. T. Yuen, J. O'Brian, R. A. Childs, W. Chai, A. M Lawson, K. Drbal, A Fiserová, M Pospísil, and T. Feizi. 1994. Oligosaccharide ligands for NKR-P1 protein activate NK cells and cytotoxicity. Nature 372:150.