Altered cJun expression: An early event in human lung carcinogenesis

Cancer Research

Volumn 56, Issue 2, 1996, Pages 305-315

  Szabo, Eva ^a   Riffe, Maura E ^a   Steinberg, Seth M ^a   Birrer, Michael J ^a   Linnoila, R Ilona ^a  

^a NATIONAL CANCER INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ARTICLE; CANCER CELL CULTURE; GENE EXPRESSION REGULATION; GROWTH REGULATION; HUMAN; HUMAN CELL; LUNG CARCINOGENESIS; LUNG NON SMALL CELL CANCER; ONCOGENE C JUN; PRIORITY JOURNAL; SIGNAL TRANSDUCTION; TUMOR PROMOTION;

CARCINOMA, NON-SMALL-CELL LUNG; FEMALE; GENE EXPRESSION; GENES, FOS; GENES, JUN; GROWTH SUBSTANCES; HUMANS; IMMUNOHISTOCHEMISTRY; LUNG NEOPLASMS; MALE; MIDDLE AGED; PROTO-ONCOGENE PROTEINS C-JUN; SIGNAL TRANSDUCTION; TRANSCRIPTION FACTOR AP-1;

EID: 0030063176     PISSN: 00085472     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (51)

1. Lamph, W. W., Wamsley, P., Sassone-Corsi, P., and Verma, I Induction of proto-oncogene JUN/AP-1 by serum and TPA. Nature (Lond.), 334: 629-631, 1988.
2. Quantin, B., and Breathnach, R. Epidermal growth factor stimulates transcription of the c-jun proto-oncogene in rat fibroblasts. Nature (Lond.), 334. 538-539, 1988.
3. Ryder, K., and Nathans, D. Induction of protooncogene c-jun by serum growth factors. Proc. Natl. Acad Sci. USA, 85: 8464-8467, 198S.
4. Castellazzi, M., Spyrou, G , LaVista, N., Dangy, J-P., Piu, F , Yaniv, M., and Brun, G. Overexpression of c-jun, junB, or junD affects cell growth differently. Proc. Natl. Acad. Sci. USA, 88: 8890-8894, 1991.
5. Bohmann, D , Bos, T J., Admon, A., Nishimura, T , Vogt, P. K., and Tjian, R. Human proto-oncogene c-jun encodes a DNA binding protein with structural and functional properties of transcription factor AP-1. Science (Washington DC), 238. 1386-1392, 1987.
6. Chiu, R., Boyle, W J , Meek, J , Smeal, T., Hunter, T., and Karin, M. The c-Fos protein interacts with c-Jun/AP-1 to stimulate transcription of AP-1 responsive genes. Cell, 54: 541-552, 1988.
7. Franza, B. R., Rauscher, F. J., Josephs, S. F , and Curran, T. The fos complex and fos-related antigens recognize sequence elements that contain AP-1 binding sites. Science (Washington DC), 239: 1150-1153, 1988.
8. Rauscher, F. J., Cohen, D R., Curran, T., Bos, T. J., Vogt, P K., Bohmann, D., Tjian, R , and Franza, B. R Fos-associated protein p39 is the product of the jun proto-oncogene Science (Washington DC), 240: 1010-1016, 1988.
9. 1 transition in mouse fibroblasts. Nature (Lond.), 334, 535-537, 1988.
10. Wu, B., Fodor, E. J. B., Edwards, R. H., and Runer, W J Nerve growth factor induces the proto-oncogene c-jun in PC12 cells. J Biol. Chem., 264: 9000-9003, 1989.
11. 1 and S Oncogene, 6: 229-235, 1991.
12. Yamaguchi-Iwai, Y., Satake, M., Murakami, Y., Sakai, M., Muramatsu, M., and Ito, Y. Differentiation of F9 embryonal carcinoma cells induced by the c-jun and activated c-Ha-ras oncogenes. Proc. Natl. Acad. Sci USA, 87: 8670-8674, 1990
13. deGroot, R. P , Kruyt, F. A. E., van der Saag, P. T., and Kruijer, W. Ectopic expression of c-jun leads to differentiation of P19 embryonal carcinoma cells. EMBO J., 9: 1831-1837, 1990.
14. Szabo, E., Preis, L. H., and Birrer, M. J. Constitutive cJun expression induces partial macrophage differentiation in U-937 cells. Cell Growth & Differ., 5: 439-446, 1994.
15. Lee, W., Mitchell, P., and Tjian, R. Purified transcription factor AP-1 interacts with TPA-inducible enhancer elements Cell. 49: 741-752, 1987.
16. Bernstein, L. R., and Colburn, N. H AP1/jun function is differentially induced in promotion-sensitive and resistant JB6 cells. Science (Washington DC), 244: 566-569, 1989.
17. Dong, Z., Birrer, M. J., Watts, R. G , Matrisian, L. M., and Colburn, N. H. Blocking of rumor promoter-induced AP-1 activity inhibits induced transformation in JB6 mouse epidermal cells. Proc. Natl. Acad. Sci. USA, 94: 609-613, 1994.
18. Heintz, N. H , Janssen, Y. M., and Mossman, B. T. Persistent induction of c-fos and c-jun expression by asbestos. Proc Natl Acad. Sci. USA, 90. 3299-3303, 1993
19. Slaughter, D. P , Southwick, H W , and Smejkal, W. Field cancerization in oral stratified squamous epithelium. Cancer (Phila.), 6: 693-698, 1953.
20. Sozzi, G., Miozzo, M., Tagliabue, E., Calderone, C., Lombardi, L., Sivana, P , Pastorino, U., Pierotti, M. A., and Delia Porta, G. Cytogenetic abnormalities and overexpression of receptors for growth factors in normal bronchial epithelium and rumor samples of lung cancer patients. Cancer Res., 51. 400-404, 1991.
21. Sozzi, G , Miozzo, M., Donghi, R., Pilotti, S., Cariani, C T., Pastorino, U., Della Porta, G., and Pierotti, M. A. Deletions of 17p and p53 mutations in preneoplastic lesions of the lung. Cancer Res., 52: 6079-6082, 1992
22. Bennett, W P., Colby, T. V., Travis, W. D., Borkowski, A., Jones, R. T., Lane, D. P., Metcalf, R. A , Samet, J M., Takeshima, Y., Gu, J. R., Vahakangas, K H., Soini, Y., Paakko, P., Welsh, J. A., Trump, B. F., and Harris, C. C. p53 protein accumulates frequently in early bronchial neoplasia. Cancer Res., 53: 4817-4822, 1993.
23. Sozzi, G., Miozzo, M., Pastorino, U., Pilotti, S., Donghi, R., Giarola, M., De Gregorio, L., Manenti, G., Radice, P., Minoletti, F., Della Porta, G., and Pierotti, M. A. Genetic evidence for an independent origin of multiple preneoplastic and neoplastic lung lesions. Cancer Res., 55: 135-140, 1995.
24. Li, Z-H., Zheng, J., Weiss, L. M., and Shibata, D. c-K-ras and p53 mutations occur very early in adenocarcinoma of the lung. Am. J. Pathol., 144: 303-309, 1994.
25. Ohshima, S., Shimizu, Y., and Takahama, M. Detection of c-Ki-ras gene mutation in paraffin sections of adenocarcinoma and atypical broncholoalveolar cell hyperplasia of human lung. Virchows Arch., 424: 129-134, 1994
26. Sugio, K., Kishimoto, Y., Virmani, A. K., Hung, J. Y , and Gazdar, A F. K-ras mutations are a relatively late event in the pathogenesis of lung carcinomas. Cancer Res., 54: 5811-5815, 1994
27. Linnoila, R. I., Mulshine, J , Steinberg, S. M. Funa, K., Matthews, M J., Cotelingham, J., and Gazdar, A F. Neuroendocrine differentiation in endocrine and non-endocrine carcinomas Am. J Clin Pathol., 90. 1-12, 1988.
28. Gown, A. M., de Wever, N., and Battifora, H. Microwave-based antigenic unmasking, a revolutionary new technique for routine immunohistochemistry. Appl. Immunohistochem., 1: 256-266, 1993.
29. Shaw, G L , Gazdar, A. F., Phelps, R., Linnoila, R. I., Ihde, D C , Johnson, B. E . Oie, H. K., Pass, H. I., Steinberg, S. M , Ghosh, B C., Walsh, T. E., Nesbitt, J. C , Cotelingham, J. D , Minna, J. D , and Mulshine, J. L. Individualized chemotherapy for patients with non-small cell lung cancer determined by prospective identification of neuroendocrine markers and in vitro drug sensitivity testing. Cancer Res., 53: 5181-5187, 1993
30. Linnoila, R I., Piantadosi, S., and Ruckdeschel, J C Impact of neuroendocrine differentiation in non-small cell lung cancer, the LCSG experience. Chest, 106 (Suppl.): 367s-371s, 1994.
31. Kaplan, E. L., and Meier, P. Nonparametric estimation from incomplete observations. J. Am Stat. Assoc., 53: 457-481, 1958.
32. Mantel, N. Evaluation of survival data and two new rank order statistics arising in its consideration. Cancer Chemother. Rep., 50: 163-170, 1966.
33. Belkowski, L. S , Fan, X , and Bloom, B. R. Transfection of murine and human macrophage-like cell lines by cationic liposomes Focus (Idaho), 11: 35, 1989.
34. German, C. M., Moffat, L. F , and Howard, B H. Recombinant genomes which express chloramphenicol acetyl transferase in mammalian cells. Mol. Cell. Biol., 2. 1044-1051, 1982.
35. Szabo, E., Preis, L. H , Brown, P. H., and Birrer, M. J. The role of jun and fos gene family members in 12-O-tetradecanoylphorbol-13-acetate induced hemopoietic differentiation. Cell Growth & Differ., 2: 475-482, 1991.
36. Fearon, E. R., and Vogelstein, B. A genetic mode! for colorectal tumorigenesis. Cell. 61: 759-767, 1990.
37. Saccomanno, G., Archer, V E., Auerbach, O., Saunders, R. P., and Brennan, L M Development of carcinoma of the lung as reflected in exfoliated cells. Cancer (Phila), 33. 256-270, 1974.
38. Noguchi, M., and Shimosato, Y The development and progression of adenocarcinoma of the lung. Cancer Treat, & Res , 72: 131-142, 1995.
39. Volm, M., Drings, P., and Wodrich, W. Prognostic significance of the expression of c-fos, c-jun, and c-erbB-1 oncogene products in human squamous cell lung carcinomas. J Cancer Res. Clin. Oncol., 119: 507-510, 1993
40. Volm, M., Drings, P., Wodrich, W., and van Kaick, G. Expression of oncoproteins in primary human non-small cell lung cancer and incidence of metastases. Clin. Exp Metastasis, 11: 325-329, 1993.
41. Wodnch, W., and Volm, M Overexpression of oncoproteins in non-small cell lung carcinomas of smokers. Carcinogenesis (Lond), 14: 1121-1124, 1993.
42. Volm, M., van Kaick, G., and Mattern, J. Analysis of c-fos, c-jun, c-erbB1, c-erbB2, and c-myc in primary lung carcinomas and their lymph node metastases Clin. Exp. Metastasis, 12: 329-334, 1994
43. Levin, W. J , Casey, G , Ramos, J. C., Arboleda, M J., Reissmann, P. T., and Slamon, D. J. Tumor suppressor and immediate early transcription factor genes in non-small cell lung cancer. Chest, 106 (Suppl.): 372s-376s, 1994
44. Adcock, I M., Shirasaki, H., Gelder, C. M., Peters, M. J., Brown, C. R., and Barnes, P. J. The effects of glucocorticoids on phorbol ester and cytokine stimulated transcription factor activation in human lung. Life Sci., 55: 1147-1153, 1994.
45. Linardopoulos, S., Papadakis, E., Delakas, D., Theodosiou, V , Cranidis, A , and Spandidos, D. A. Human lung and bladder carcinoma tumors as compared to their adjacent normal tissue have elevated AP-1 activity associated with the retinoblastoma gene promoter. Anticancer Res , 13: 257-262, 1993.
46. Sakai, M., Okuda, A., Hatayama, I , Sato, K., Nishi, S., and Muramatsu, M. Structure and expression of the rat c-jun messenger RNA, tissue distribution and increase daring chemical hepatocarcinogenesis. Cancer Res., 49: 5633-5637, 1989.
47. Suzuki, S., Satoh, K., Nakano, H., Hatayama, I., Sato, K., and Tsuchida, S. Lack of correlated expression between the glutathione S-transferase P-form and the oncogene products of c-Jun and c-Fos in rat tissues and preneoplastic hepatic foci. Carcinogenesis (Lond.), 16: 567-571, 1995.
48. 2 is directly related to increased proliferation and transformation of tracheal epithelial cells. Cancer Res., 55: 2723-2726, 1995
49. Dolan, L. R., Rutberg, S. E., Amin, S., Emura, M., Mohr, U., Kraft, A., Yokoyama, K., and Ronai, Z. Regulation of c-jun by lung carcinogens in Clara cells of hamsters. Carcinogenesis (Lond.), 15: 2789-2793, 1994.
50. Yamit-Hezi, A., Plaksin, D., and Eisenbach, L. c-fos and c-jun overexpression in malignant cells reduces their tumorigenic and metastatic potential and affects their MHC class I gene expression Oncogene, 9: 1065-1079, 1994.
51. Minna, J. D., Schutte, J., Viallet, J., Thoman, F., Kaye, F. J., Takahashi, T., Nau, M., Whang-Peng, J., Birrer, M., and Gazdar, A. Transcription factors and recessive oncogenes in the pathogenesis of human lung cancer. Int. J. Cancer, 4 (Suppl.): 32-34, 1989.