Hypotension-induced expression of the c-fos gene in the medulla oblongata of piglets

Brain Research

Volumn 706, Issue 2, 1996, Pages 199-209

  Ruggiero, D A ^a,b   Tong, S ^c   Anwar, M ^a   Gootman, N ^c   Gootman, P M ^c  

^a WEILL CORNELL MEDICAL COLLEGE   (United States)

^b Neurological Research Institute of Lubec   (United States)

^c SUNY DOWNSTATE MEDICAL CENTER   (United States)

Author keywords

Autonomic nervous system; Blood pressure; Catecholamine; Functional activity; Gene induction; Immediate early response gene; Neonate

Indexed keywords

NITROPRUSSIDE SODIUM; TYROSINE 3 MONOOXYGENASE;

ADOLESCENT; ANIMAL EXPERIMENT; ARTICLE; BLOOD PRESSURE; BRAIN REGION; CONTROLLED STUDY; GENE EXPRESSION; HYPOTENSION; IMMUNOCYTOCHEMISTRY; MEDULLA OBLONGATA; NEWBORN; NONHUMAN; PRIORITY JOURNAL; SOLITARY TRACT NUCLEUS; SWINE;

EID: 0030063172     PISSN: 00068993     EISSN: None     Source Type: Journal    
DOI: 10.1016/0006-8993(95)01173-0     Document Type: Article

References (62)

1. Barman, S.M. and Gebber, G.L., Rostral ventrolateral medullary and caudal medullary raphe neurons with activity correlated to the 10Hz rhythm in sympathetic nerve discharge, J. Neurophysiol., 68 (1992) 1535-1547.
2. Barman, S.M. and Gebber, G.L., Lateral tegmental field neurons play a permissive role in governing the 10-Hz rhythm in sympathetic nerve discharge, Am J. Physiol., 265 (1993) R1006-R1013.
3. Badoer, E., McKinley, M.J., Oldfield, B.J. and McAllen, R.M., Distribution of hypothalamic, medulllary and lamina terminalis neurons expressing fos after hemorrhage in a conscious rat, Brain Res., 582 (1992) 323-328.
4. Chalmers, J., Arnilda, L., Llewellyn-Smith, I., Minson, J., Pilowsky, P. and Suzuki, S., Central neurons and neurotransmitters in the control of blood pressure, Clin. Exp. Pharmacol. Physiol., 21 (1994) 819-829.
5. Chan, R.K.W. and Sawchenko, P.E., Spatially and temporally differentiated patterns of c-fos expression in brainstem catecholaminergic cell groups induced by cardiovascular challenges in the rat, J. Comp. Neurol., 348 (1994) 433-460.
6. Ciriello, J., Brainstem projections of aortic baroreceptor afferent fibres in the rat, Neurosci. Lett., 36 (1983) 37-42.
7. Cohen, H.L., Gootman, P.M., Hundley, B.W., Condemi, G. and Eberle, L.P., Power spectral analysis of the baroreflex in neonatal swine, Brain Res., 558 (1991) 131-135.
8. Cunningham, E.T., Jr. and Sawchenko, P.E., Anatomical specificity of noradrenergic inputs to the paraventricular and supraoptic nuclei of the rat hypothalamus, J. Comp. Neurol., 274 (1990) 60-76.
9. Curran, T. and Franza, B.R., Jr., Fos and Jun: the AP-1 connection, Cell, 55 (1988) 395-397.
10. Davis, D.W., Hawkins, R.A., Mans, A.M., Hibbard, L.S. and Biebuyck, J.F., Regional cerebral glucose utilization during Althesin anesthesia, Anesthesiology, 61 (1984) 362-368.
11. Day, T.A., Sibbald, J.R. and Smith, D.W., A1 neurons and excitatory amino acid receptors in rat caudal medulla mediate vagal excitation of supraoptic vasopressin cells, Brain Res., 594 (1992) 244-252.
12. Donoghue, S., Felder, R.B., Jordan, D. and Spyer, K.M., The central projections of carotid baroreceptors and chemoreceptors in the cat: a neurophysiological study, J. Physiol., 347 (1984) 397-409.
13. Dun, N.J., Dun, S.L. and Chiaia, N.L., Hemorrhage induces Fos immunoreactivity in rat medullary catecholaminergic neurons, Brain Res., 608 (1993) 223-232.
14. Erickson, J.T. and Millhorn, D.E., Fos-like protein is induced in neurons of the medulla oblongata after stimulation of the carotid sinus nerve in awake and anesthetized rats, Brain Res., 567 (1991) 11-24.
15. 2-adrenergic modulation of synaptic excitability in the rat nucleus tractus solitarius, Brain Res., 480 (1989) 190-197.
16. Ferrari, M., Wilson, D.A., Hanley, D.F. and Traystman, R.J., Effects of graded hypotension on cerebral blood flow, blood volume, and mean transient time in dogs, Am. J. Physiol., 262 (1992) H1908-H1914.
17. Gomez, R.E., Cannata, T.A., Milner, T.A., Anwar, M. Reis, D.J. and Ruggiero, D.A., Vasopressinergic mechanisms in the nucleus reticularis lateralis in blood control, Brain Res., 604 (1993) 90-105.
18. Gootman, P.M., Cohen, H.L., Steele, A.M., Sica, A.L., Condemi, G., Gandhi, M.R. and Eberle, L.P., Effects of anesthesia on efferent phrenic activity in neonatal swine, Brain Res., 522 (1990) 131-134.
19. Gootman, P.M. and Cohen, M.I., Efferent splanchnic activity and systemic arterial pressure, Am. J. Physiol., 219 (1970) 897-903.
20. Gootman, P.M. and Cohen, M.I., Evoked potentials produced by electrical stimulation of medullary vasomotor regions, Exp. Brain Res., 13 (1971) 1-14.
21. Gootman, P.M. and Cohen, M.I., Periodic modulation (cardiac and respiratory) of spontaneous and evoked sympathetic discharge, Acta Physiol. Polon., 24 (1973) 99-109.
22. Gootman, P.M., Cohen, M.I., Piercey, M.P. and Wolotsky, P., A search for medullary neurons with activity patterns similar to those in sympathetic nerves, Brain Res., 87 (1975) 395-406.
23. Gootman, P.M., Gandhi, M.R., Steele, A.M., Hundley, B.W., Cohen, H.L., Eberle, L.P. and Sica, A.L., Respiratory modulation of sympathetic activity in neonatal swine, Am. J. Physiol., 261 (1991) R1147-R1154.
24. Gootman, P.M., Hundley, B.W., Condemi, G. and Cohen, H.L., Postnatal development of cardiovascular and sympathetic responses to simulated Valsalva maneuvers in neonatal swine. In M. Yoshikawa, M. Uono, H. Tanabe, S. Ishikawa (Eds.), New Trends in Autonomic Nervous System Research, Basic and Clinical Integration, Elsevier Science Publishers, New York, 1991, pp. 349-351.
25. Gootman, P.M., Hundley, B.W., Sica, A.L. and Gootman, N., Coherence of efferent sympathetic activity and phrenic discharge in a neonatal animal: relation to SIDS. In T.O. Rognum (Ed.), Sudden Infant Death Syndrome. New Trends in the Nineties, Scandinavian University Press, 1995, pp. 235-241.
26. Gootman, P.M. and Sica, A.L., Spectral analysis: A tool for study of neonatal sympathetic systems, News Physiol. Sci., 9 (1994) 233-236.
27. Gordon, F.J., Aortic baroreceptor reflexes are mediated by NMDA receptors in caudal ventrolateral medulla, Am. J. Physiol., 252 (1987) R628-R633.
28. Grubb, R.L. and Raichle, M.E., Effects of hemorrhage and pharmacologic hypotension on cerebral oxygen utilization and blood flow, Anesthesiology, 36 (1982) 3-8.
29. Guyenet, P.G., Role of the ventral medulla oblongata in blood pressure regulation. In A.D. Loewy and K.M. Spyer (Eds.), Central Regulation of Autonomic Functions, Oxford Univ. Press, NY, 1990, pp. 145-167.
30. Hopkins, D.A., Gootman, P.M., Gootman, N., DiRusso, S.M. and Zeballos, M.E., Brainstem cells of origin of the cervical vagus and cardiopulmonary nerves in the neonatal pig (Sus scrofa), Brain Res., 306 (1984) 63-72.
31. Housley, G.D., Martin-Body, R.L., Dawson, N.J. and Sinclair, J.D., Brain stem projections of the glossopharyngeal nerve and its carotid sinus branch in the rat, Neuroscience, 6 (1987) 237-250.
32. Ivanovich, A.D., Miletich, D.J., Abrecht, R.F. and Zahed, B., Sodium nitroprusside and cerebral blood flow in the anesthetized and unanesthetized goat, Anesthesiology, 44 (1976) 21-26.
33. Kobashi, M., Ichikawa, H., Sugimoto, T. and Adachi, A., Response of neurons in the solitary tract nucleus, area postrema and lateral parabrachial nucleus to gastric load of hypertonic saline, Neurosci. Lett., 158 (1993) 47-50.
34. Kreye, V.A.W., Sodium nitroprusside: approaches towards elucidation of its mode of action, Trends Pharmacol. Sci., 1 (1980) 384-388.
35. Krukoff, T.L., Expression of c-fos in studies of central autonomic and sensory systems, Mol. Neurobiol., 7 (1994) 247-263.
36. Kumada, M., Terui, N. and Kuwaki, T., Arterial baroreceptor reflex-its central and peripheral neural mechanisms, Prog. Neurobiol., 35 (1990) 331-361.
37. Lee, W.M.F., Lin, C. and Curran, T., Activation of the transforming potential of the human Fos proto-oncogene requires message stabilization and results in increased amounts of partially modified Fos protein, Molec. Cell. Biol., 8 (1988) 5521-5527.
38. Li, Y.-W. and Dampney, R.A.L., Expression of c-fos protein in the medulla oblongata of conscious rabbits in response to baroreceptor activation, Neurosci. Lett., 144 (1992) 70-74.
39. Li, Y.-W. and Dampney, R.A.L., Expression of Fos-like protein in brain following sustained hypertension and hypotension in conscious rabbits, Neuroscience, 61 (1994) 613-634.
40. McAllen, R.M., Badoer, E., Shafton, A.D., Oldfield, B.J. and McKinley, M.J., Hemorrhage induces c-fos immunoreactivity in spinally projecting neurons of cat subretrofacial nucleus, Brain Res., 575 (1992) 329-332.
41. McKitrick, M.J., Krukoff, T.L. and Calaresu, F.R., Expression of c-fos protein in rat brain after electrical stimulation of the aortic depressor nerve, Brain Res., 599 (1992) 215-222.
42. Miller, A.D. and Ruggiero, D.A., Emetic reflex arc revealed by expression of the immediate-early gene c-fos in the cat, J. Neurosci., 14 (1994) 871-888.
43. Minson, J.B., Llewellyn-Smith, I.J., Arnolda, L.F., Pilowsky, P.M., Oliver, J.R. and Chalmers, J.P., Disinhibition of the rostral ventral medulla increases blood pressure and FOS expression in bulbospinal neurons, Brain Res., 646 (1994) 44-52.
44. Miura, M., Takayama, K. and Okada, J., Neuronal expression of Fos protein in the rat brain after baroreceptor stimulation, J. Auton. Nerv. Syst., 50 (1994) 31-43.
45. Morgan, J.I. and Curran, T., Stimulus-transcription coupling in the nervous system: involvement of the inducible proto-oncogenes fos and jun, Annu. Rev. Neurosci., 1 (1991) 421-251.
46. Mtui, E.P., Anwar, M., Reis, D.J. and Ruggiero, D.A., Medullary visceral reflex circuits: Local afferents to nucleus tractus solitarii synthesize catecholamines and project to thoracic spinal cord, J. Comp. Neurol., 351 (1995) 5-26.
47. Ross, C.A., Ruggiero, D.A., Park, D.H., Joh, T.H., Sved, A.F., Fernandez-Pardal, J.M. and Reis, D.J., Tonic vasomotor control by the rostral ventrolateral medulla: effect of electrical or chemical stimulation of the area containing C1 adrenaline neurons on arterial pressure, heart rate, and plasma catecholamines and vasopressin, J. Neurosci., 4 (1984) 474-494.
48. Ruggiero, D.A., Anwar, M. and Gootman, P.M., Presumptive adrenergic neurons containing phenylethanolamine N-methyltransferase immunoreactivity in the medulla oblongata of neonatal swine, Brain Res., 583 (1992) 105-119.
49. Ruggiero, D.A., Cravo, S.L., Arango, V. and Reis, D.J., Central control of the circulation by the rostral ventrolateral reticular nucleus: Anatomical substrates. In J. Ciriello, C. Polosa and C. Caverson (Eds.), Progress in Brain Research, Elsevier, Amsterdam, 1989, pp. 49-79.
50. Ruggiero, D.A., Cravo, S.L., Golanov, E., Gomez, R., Anwar, M. and Reis, D.J., Adrenergic and non-adrenergic spinal projections of a cardiovascular-active presser area of medulla oblongata: quantitative topographic analysis, Brain Res., 663 (1994) 107-120.
51. Ruggiero, D.A., Gomez, R.E., Cravo, S.L., Mtui, M., Anwar, M. and Reis, D.J., The rostral ventrolateral medulla: Anatomical substrates of cardiopulmonary integration. In H.-P. Koepchen and T. Huopaniemi (Eds.), Cardiorespiratory and Motor Coordination, Springer-Verlag, New York, 1991, pp. 89-102.
52. Ruggiero, D.A., Meeley, M.P., Anwar, M. and Reis, D.J., Newly identified GABAergic neurons in regions of the ventrolateral medulla that regulate blood pressure, Brain Res., 339 (1985) 171-177.
53. Ruggiero, D.A., Pickel, V.M., Milner, T.A., Anwar, M., Otake, K., Mtui, E.P. and Park, D., Viscerosensory processing in nucleus tractus solitarii: Structural and neurochemical substrates. In R.A. Barraco (Ed.), Nucleus of the Solitary Tract, CRC Press, Boca Raton, FL, 1994, pp. 3-34.
54. Salinas-Zeballos, M.-E., Zeballos, G.A. and Gootman, P.M., A stereotaxic atlas of developing swine (Sus scrofa) forebrain. In M.E. Tumbleson (Ed.), Swine in Biomedical Research, Plenum Publ., NY, 1986, p. 887-906.
55. 2 chemoreceptor neuron identification by c-fos immunocytochemistry, J. Appl. Physiol., 73 (1992) 96-100.
56. Shen, E., Dun, S.L., Ren, C. and Dun, N.J., Hypovolemia induces Fos-like immunoreactivity in neurons of the rat supraoptic and paraventricular nuclei, J. Auton. Nerv. Syst., 37 (1992) 227-230.
57. Shen, E., Dun, S.L., Ren, C., Bennett-Clarke, C. and Dun, N.J., Hypotension preferentially induces c-fos immunoreactivity in supraoptic vasopressin neurons, Brain Res., 593 (1992) 136-139.
58. Spyer, K.M., Central nervous mechanisms contributing to cardiovascular control, J. Physiol., 474 (1994) 1-19.
59. Sved, A.F., Mancini, D.L., Graham, J.C., Schreihoffer, A.M. and Hoffman, G.E., PNMT-containing neurons of the C1 cell group express c-fos in response to changes in baroreceptor input, Am. J. Physiol., 266 (1994) R361-R367.
60. Takayama, K., Suzuki, T. and Miura, M., The comparison of effects of various anesthetics on expression of Fos protein in the rat brain, Neurosci. Lett., 176 (1994) 59-62.
61. Tong, S., Ingenito, S., Anderson, J.E., Gootman, N., Sica, A.L. and Gootman, P.M., Development of a swine animal model for the study of Sudden Infant Death Syndrome (SIDS), Lab. Anim. Sci., 45 (1995) 398-403.
62. Trzebski, A., Homeodynamics versus homeostasis: periodicities superimposed on non-linear dynamic sympathetic tone generated in ventral medulla, Acta Neurobiol. Exp., 54 (1994) 109-125.