Rational design of granulocyte-macrophage colony-stimulating factor antagonist peptides

Journal of Biological Chemistry

Volumn 271, Issue 6, 1996, Pages 2966-2971

  Monfardini, Cristina ^a,b   Kieber Emmons, Thomas ^b   Voet, Donald ^b   Godillot, A Paul ^a,b   Weiner, David B ^a,b   Williams, William V ^a,b,c  

^a UNIVERSITY OF PENNSYLVANIA   (United States)

^b UNIVERSITY OF PENNSYLVANIA   (United States)

^c CHILDREN S HOSPITAL OF PHILADELPHIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

COLONY STIMULATING FACTOR; COLONY STIMULATING FACTOR ANTAGONIST; COLONY STIMULATING FACTOR RECEPTOR; CYCLOPEPTIDE; CYTOKINE; GRANULOCYTE MACROPHAGE COLONY STIMULATING FACTOR; HEMOPOIETIC GROWTH FACTOR; UNCLASSIFIED DRUG;

APOPTOSIS; ARTICLE; BONE MARROW RESCUE; CANCER ADJUVANT THERAPY; CANCER IMMUNOTHERAPY; CELL STRAIN HL 60; CONTROLLED STUDY; DRUG DESIGN; HEMATOPOIESIS; HUMAN; HUMAN CELL; IMMUNOMODULATION; INFLAMMATION; PRIORITY JOURNAL;

AMINO ACID SEQUENCE; ANTIBODIES; APOPTOSIS; DRUG DESIGN; ENZYME-LINKED IMMUNOSORBENT ASSAY; GRANULOCYTE-MACROPHAGE COLONY-STIMULATING FACTOR; HL-60 CELLS; HUMANS; KINETICS; MODELS, STRUCTURAL; MOLECULAR SEQUENCE DATA; PEPTIDES, CYCLIC; PROTEIN STRUCTURE, SECONDARY; RADIOLIGAND ASSAY; RECEPTORS, GRANULOCYTE-MACROPHAGE COLONY-STIMULATING FACTOR; RECOMBINANT PROTEINS; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 0030063097     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.271.6.2966     Document Type: Article

References (52)

1. Weisbart, R., and Golde, D. (1989) Hematol. Oncol. Clin. North Am. 3, 401-409
2. Antman, K. H. (1993) Eur. J. Cancer 3, S2-S6
3. Tao, M.-H., and Levy, R. (1993) Nature 362, 755-758
4. Dranoff, G., Jaffee, E., Lazenby, A., Golumbek, P., Levitsky, H., Brase, K., Jackson, V., Hamada, H., Pardoll, D., and Mulligan, R. C. (1993) Proc. Natl. Acad. Sci U. S. A. 90, 3539-3343
5. Diederichs, K., Boone, T , and Karplus, P. A. (1991) Science 254, 1779-1782
6. Diederichs, K., Jacques, S , Boone, T., and Karplus, P. A. (1991) J. Mol. Biol. 221, 55-60
7. LaLonde, J. M., Hanna, L. S , Rattoballi, R., Berman, H. M., and Voet, D. (1989) J. Mol. Biol. 205, 783-785
8. Walter, M. R., Cook, W J., Ealick, S. E., Nagabhushan, T. L., Trotta, P. P., and Bugg, C. E. (1992) J. Mol. Biol 224, 1075-1085
9. deVos, A. M., Ultsch, M., and Kossiakoff, A. A. (1992) Science 255, 306-312
10. Brandhuber, B. J., Boone, T., Kenney, W. C., and McKay, D B. (1987) Science 238, 1707-1709
11. Garrett, D. S., Powers, R., March, C. J., Frieden, E. A., Clore, G. M., and Gronenborn, A. M (1992) Biochemistry 31, 4347-4353
12. Powers, R., Garrett, D S., March, C. J., Frieden. E. A., Gronenborn, A. M., and Clore, G. M. (1993) Biochemistry 32, 6744-6762
13. Redfield, C., Boyd, J., Smith, L J., Smith, R. A , and Dobson, C. M. (1992) Biochemistry 31, 10431-10437
14. Smith, L J., Redfield, C., Boyd, J., Lawrence, G. M , Edwards, R. G., Smith, R. A., and Dobson, C. M. (1992) J. Mol. Biol. 224, 899-904
15. Pandit, J., Bohm, A , Jancarik, J., Halenbeck, R., Koths, K., and Kim, S. H. (1992) Science 258, 1358-13562
16. Milburn, M V , Hassell, A. M , Lambert, M. H., Jordan, S. R , Proudfoot, A E., Graber, P., and Wells, T. N. (1993) Nature 363, 172-1726
17. Chiba, S , Tojo, A., Kitamura, T., Urabe, A., Miyazono, K., and Takaku, F. (1990) Leukemia 4, 29-36
18. Cannistra, S. A , Groshek, P., Garlick, R., Miller, J., and Griffin, J. D (1990) Proc. Natl. Acad Sci. U. S A. 87, 93-97
19. DiPersio, J., Billing, P., Kaufman, S , Eghtesady, P., Williams, R E., and Gasson, J. C. (1988) J. Biol. Chem. 263, 1834-1841
20. Gearing, D. P., King. J. A., Gough, N. M., and Nicola, N. A. (1989) EMBO J. 8, 3667-3676
21. Hayashida, K., Kitamura, T., Gorman, D. M., Arai, K.-I., Yokota, T., and Miyajima, A (1990) Proc. Natl. Acad. Sci. U. S. A. 87, 9655-9659
22. Park, L , Friend, D., Gillis, S., and Urdal, D. (1986) J. Biol. Chem 261, 4177-4183
23. Onetto-Pothier, N., Aumont, N., Haman, A , Bigras, C., Wong, G. G., Clark, S C., De Lean, A., and Hoang, T (1990) Blood 75, 59-66
24. Shanafelt, A. B., and Kastelein, R. A. (1992) J. Biol. Chem. 267, 25466-25472
25. Yokota, T., Watanabe, S , Mui, A. L., Muto, A., Miyajima, A., and Arai, K. (1993) Leukemia 7, S102-S107
26. Sakamaki, K., Miyajima, I., Kitamura, T., and Miyajima, A. (1992) EMBO J. 11, 3541-3549
27. VonFeldt, J. M., Monfardini, C., Fish, S., Rosenbaum, H., Kieber-Emmons, T., Williams, R. M., Kahn, S A , Weiner, D B., and Williams, W. V. (1995) Peptide Res 8, 20-32
28. Monfardini, C , Kieber-Emmons, T., VonFeldt, J. M., O'Malley, B., Rosenbaum, H., Godillot, A. P., Kaushansky, K., Brown, C. B., Voet, D , McCallus, D. E , Weiner, D B , and Williams, W. V. (1995) J. Biol. Chem. 270, 6628-6638
29. Williams, W., Guy, H , Rubm, D., Robey, F., Myers, J , Kieber-Emmons, T., Weiner, D., and Greene, M. (1988) Proc. Natl. Acad. Sci. U. S. A. 85, 6488-6492
30. Williams, W , Moss, D., Kieber-Emmons, T., Cohen, J., Myers, J., Weiner, D., and Greene, M (1989) Proc. Natl Acad Sci. U. S. A. 86, 5537-5541
31. Williams, W , Kieber-Emmons, T., Weiner, D. Rubin, D., and Greene, M. (1991) J. Biol. Chem. 266, 9241-9250
32. Williams, W., Kieber-Emmons, T., VonFeldt, J., Greene, M. I , and Weiner, D. (1991) J Biol. Chem. 266, 5182-5190
33. VonFeldt, J. M., Monfardini, C., Kieber-Emmons, T., Voet, D., Weiner, D. B., and Williams, W. V. (1994.) Immunol. Res. 13, 96-109
34. Ugen, K. E., Goedert, J. J , Boyer, J., Refaeli, Y., Frank, I., Williams, W. V., Willoughby, A , Landesman, S., Mendez, H., Rubinstein, A., Keiber-Emmons, T., and Weiner, D B. (1992) J. Clin. Invest. 89, 1923-1930
35. Kaushansky, K., Shoemaker, S., Alfaro, S , and Brown, C. (1989) Proc. Natl. Acad. Sci U. S. A 86, 1213-1217
36. Cheng, Y. C., and Prusoff, W. H. (1973) Biochem. Pharmacol. 22, 3099-3108
37. Rajotte, D., Haddad, P., Haman, A., Cragoe, E. J., Jr , and Hoang, T. (1992) J. Biol. Chem. 267, 9980-9987
38. Hone. M , and Broxmeyer, H E. (1995) Exp Hematol. 23, 168-173
39. Lopez, A. F., Shannon, M. F., Hereus, T., Nicola, N. A., Cambareri, B., Dottore, M., Layton, M. J., Eglinton, L., and Vadas, M A (1992) EMBO J. 11, 909-916
40. Shanafelt, A. B., Miyajima, A., Kitamura, T, and Kasteleim, R. A. (1991) EMBO J. 10, 4105-4112
41. Hercus, T. R , Bagley, C. J., Cambareri, B , Dottore, M., Woodcock, J. M., Vadas, M. A., Shannon, M. F., and Lopez, A. F. (1994) Proc. Natl. Acad. Sci. U S. A. 91, 5838-5842
42. Hercus, T R., Cambaren, B., Dottore, M., Woodcock, J., Bagley, C. J., Vadas, M. A., Shannon, M. F., and Lopez, A. F. (1994) Blood 83, 3500-3508
43. Gough, N., Grail, D., Gearing, D , and Metcalf, D. (1987) Eur. J. Biochem. 169, 353-358
44. Shanafelt, A. B , and Kastelein, R. A. (1989) Proc. Natl Acad Sci U. S. A. 86, 4872-4876
45. Altmann, S. W , Johnson, G D., and Prystowky, M. B. (1991) J. Biol. Chem. 266, 5333-5341
46. Brown, C. B., Hart, C. E , Curtis, D. M., Bailey, M. C., and Kaushansky, K. (1990) J. Immunol. 144, 2184-2189
47. Kanakura, Y., Cannistra, S. A., Brown, C. B., Nakamura, M., Seelig, G. F., Prosise, W. W., Hawkins, J. C., Kaushansky, K., and Griffin, J. D. (1991) Blood 77, 1033-1043
48. Nice, E., Dempsey, P., Layton, J., Morstyn, G., Cui, D. F , Simpson, R., Fabri, L , and Burgess, A. (1990) Growth Factors 3, 159-169
49. Seelig, G., Prosise, W , Scheffler, J., Nagabhushan, T., and Trotta, P. (1990) J. Cell. Biochem. 14C, 246
50. Brown, C. B., Pihl, C. E., and Kaushansky, K (1994) Eur. J. Biochem. 225, 873-880
51. Greenfield, R. S , Braslawsky, G. R., Kadow, K. F , Spitalny, G L., Chace, D., Bull, C. O., and Bursuker, I. (1993) J. Immunol. 150, 5241-5251
52. Clark-Lewis, L, Lopez, A. F., To, L B., Vadas, M. A., Schrader, J. W., Hood, L. E., and Kent, S. B. H. (1988) J. Immunol. 141, 881-889