Glucocorticoids induced down-regulation of glucocorticoid receptor mRNA expression in asthma

Clinical and Experimental Immunology

Volumn 103, Issue 2, 1996, Pages 311-315

  Vachier, I ^a   Roux, S ^b   Chanez, P ^a   Loubatiere J ^b   Terouanne B ^b   Nicolas, J C ^b   Godard, P ^a  

^a HÔPITAL ARNAUD DE VILLENEUVE   (France)

^b INSERM   (France)

Author keywords

Asthma; Corticosteroids; Glucocorticoid receptor; Human blood monocytes; mRNA

Indexed keywords

GLUCOCORTICOID; GLUCOCORTICOID RECEPTOR; MESSENGER RNA; METHYLPREDNISOLONE;

ADULT; ARTICLE; ASTHMA; CLINICAL ARTICLE; CLINICAL TRIAL; FEMALE; FORCED EXPIRATORY VOLUME; HUMAN; MALE; MONOCYTE; PRIORITY JOURNAL;

EID: 0030062999     PISSN: 00099104     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1365-2249.1996.d01-628.x     Document Type: Article

References (29)

1. Miesfield RL. Molecular genetics of corticosteroid action. Am Rev Respir Dis 1990; 141:11-17.
2. Rinehart JJ, Sagone AL, Balcerzack SP, Ackerman A, Lobuglio AF. Effects of corticosteroid therapy on human monocyte function. N Eng J Med 1975; 292:236-41.
3. Barnes PJ, Adock I. Anti-inflammatory actions of steroids; molecular mechanisms. TiPS 1993; 14:436-41.
4. Okret S, Dong Y, Brönnegard M, Gustafsson JA. Regulation of glucocorticoid receptor expression. Biochimie 1991; 73:51-59.
5. Silva CM, Powell-Oliver FE, Jewell CM, Sar M, Allgood VE, Cidlowski JA. Regulation of the human glucocorticoid receptor by long-term and chronic treatment with glucocorticoid. Steroids 1994; 59:436-42.
6. Poston RN, Chanez P, Lacoste JY, Litchfield T, Lee TH, Bousquet J. Immunohistochemical characterization of the cellular infiltration in asthmatic bronchi. Am Rev Respir Dis 1992; 145:918-21.
7. Vachier I, Chanez P, Le Doucen C, Damon M, Descomps B, Godard P. Enhancement of reactive oxygen species formation in stable and unstable asthmatic patients. Eur Respir J 1994; 7:1585-92.
8. Wilkinson JR, Lane SJ, Lee TH. Effects of corticosteroids on cytokine generation and expression of activation antigens by monocytes in bronchial asthma. Int Arch Allergy Appl Immunol 1991; 94:220-1.
9. Adcock IM, Brown CR, Peters MJ et al. DNA binding of glucocorticoid receptor from peripheral blood monocytes of steroid sensitive and resistant patients. Am Rev Respir Dis 1993; 147:A244 (Abstr.).
10. Sher ER, Leung DYM, Surs W et al. Steroid resistant asthma. J Clin Invest 1993; 93:33-39.
11. Burnstein KL, Cidlowski JA. The down side of glucocorticoid receptor regulation. Mol Cell Endocrinol 1992; 83:C1-C8.
12. American Thoracic Society. Standard for diagnosis and care of patients with chronic obstructive disease (COPD) and asthma. Am Rev Respir Dis 1997; 136:225-45.
13. Aas K. Heterogeneity of bronchial asthma: subpopulation or different stages of the disease. Allergy 1981; 36:3-14.
14. Vachier I, Damon M, Le Doucen C et al. Increased oxygen species generation in blood monocytes of asthmatic patients. Am Rev Respir Dis 1992; 146:1161-6.
15. Polgar K, Abel G, Sipka S, Papp Z. Neutral-red uptake and expression of monocytic antigens in amniotic-fluid mononuclear phagocytes. An J Reprod Immunol Microbiol 1988; 18:81-6.
16. Chomczynski P, Sacchi N. Single-step method of RNA isolation by acid guanidium thiocyanate-phenol-chloroform extraction. Anal Biochem 1987; 162:156-9.
17. Chelly J, Kaplan JC, Maire P, Gautron S, Khan A. Transcription of the dystrophin gene in human muscle and non-muscle tissues. Nature 1988; 333:858-60.
18. Rappolee DA, Werb Z. mRNA phenotyping to study gene expression in small numbers of cells: platelet-derived growth factor and other factors in wound-derived macrophages. Am J Respir Cell Mol Biol 1990; 2:3-10.
19. Roux S, Térouanne B, Defacque H, Vachier I, Loubatière J, Nicolas JC. Nonradioactive quantification of glucocorticoid receptor expression during differentiation of human monocytic cells (U937). Anal Biochem 1995; 227:235-41.
20. Térouanne B, Balaguer P, Boussioux AM, Nicolas JC. Quantitative and qualitative analysis of amplified DNA sequences by a competitive hybridization assay. Anal Biochem 1992; 205:193-9.
21. Balaguer P, Térouanne B, Villebrun MA, Boussioux AM, Nicolas JC. Glucose 6-phosphate dehydrogenase. Non isotopic DNA probe techniques Kricka LJ, ed. New York: Academic Press, 1992.
22. Reversibility of airflow obstruction: FEV1 vs peak flow. Lancet 1992; 340:85-86.
23. Carmichael J, Palerson IC, Diaz P, Crompton GF, Kay AB, Grant IWB. Corticosteroid resistance in chronic asthma. Br Med J 1981; 282:1419-22.
24. Oka T, Matsunaga H, Tokunaga K, Mitsunaga S, Juji T, Yamane A. A simple method for detecting single base substitution and its application to HLA-DPB1 typing. Nucl Acids Res 1994; 22:1541-7.
25. Schleimer RP. Effects of glucocorticoids on inflammatory cells relevant to their therapeutic application in asthma. Am Rev Respir Dis 1990; 141:S59-69.
26. Adock IM, Bronnegard M, Barnes PJ. Glucocorticoid receptor mRNA localization and expression in human lung. Am Rev Respir Dis 1991; 143:A628.
27. Rosewicz S, MacDonald AR, Maddux BA, Godfine ID, Miesfeld RL, Logsden CD. Mechanism of glucocorticoid receptor down-regulation by glucocorticoids. J Biol Chem 1988; 263:2581-4.
28. Okret S, Poellinger L, Dong Y, Gustafson JA. Down-regulation of glucocorticoid receptor mRNA by glucocorticoid hormones and recognition by the receptor of a specific binding sequence within a receptor cDNA clone. Proc Natl Acad Sci USA 1986; 83:5899-903.
29. Schlaghecke R, Beuscher D, Kornely E, Specker C. Effect of glucocorticoid receptors do not result in glucocorticoid resistance. Arthritis Rheum 1994; 37:1127-31.