Codon adjustment to maximise heterologous gene expression in Streptomyces lividans can lead to decreased mRNA stability and protein yield

Molecular and General Genetics

Volumn 250, Issue 2, 1996, Pages 223-229

  Lammertyn, Elke ^a   Van Mellaert, Lieve ^a   Bijnens, Ann Pascale ^a   Joris, Bernard ^b   Anné, Jozef ^a  

^a REGA INSTITUTE FOR MEDICAL RESEARCH   (Belgium)

^b UNIVERSITY OF LIÈGE   (Belgium)

Author keywords

Codon bias; Heterologous gene expression; mRNA stability; Streptomyces lividans

Indexed keywords

MESSENGER RNA; TUMOR NECROSIS FACTOR;

ARTICLE; CODON; GENE EXPRESSION; NONHUMAN; NORTHERN BLOTTING; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN SECRETION; PROTEIN SYNTHESIS REGULATION; STREPTOMYCES LIVIDANS;

ALGORITHMS; ALPHA-AMYLASE; BASE SEQUENCE; BLOTTING, NORTHERN; CLONING, MOLECULAR; CODON; CODON, INITIATOR; DNA PRIMERS; GENE EXPRESSION; MOLECULAR SEQUENCE DATA; MUTAGENESIS, SITE-DIRECTED; NUCLEIC ACID CONFORMATION; PROMOTER REGIONS (GENETICS); PROTEIN SORTING SIGNALS; RECOMBINANT FUSION PROTEINS; RNA, MESSENGER; SOFTWARE; STREPTOMYCES; TUMOR NECROSIS FACTOR-ALPHA;

EID: 0030062876     PISSN: 00268925     EISSN: None     Source Type: Journal    
DOI: 10.1007/s004380050070     Document Type: Article

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