Neuroimaging findings in patients on immunosuppressive therapy: Experience with tacrolimus toxicity

American Journal of Roentgenology

Volumn 166, Issue 3, 1996, Pages 683-688

  Appignani, Barbara A ^a   Bhadelia, Rafeeque A ^a   Blacklow, Stephen C ^b   Wang, Annabel K ^a   Roland, Suzanne F ^a   Freeman Jr , Richard B ^c  

^a TUFTS MEDICAL CENTER   (United States)

^b BRIGHAM AND WOMEN S HOSPITAL   (United States)

^c TUFTS UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

TACROLIMUS;

ARTICLE; BRAIN TOXICITY; CLINICAL ARTICLE; COMPUTER ASSISTED TOMOGRAPHY; DIAGNOSTIC IMAGING; HUMAN; IMMUNOSUPPRESSIVE TREATMENT; LIVER TRANSPLANTATION; NUCLEAR MAGNETIC RESONANCE IMAGING; PRIORITY JOURNAL;

EID: 0030062819     PISSN: 0361803X     EISSN: None     Source Type: Journal    
DOI: 10.2214/ajr.166.3.8623651     Document Type: Article

References (22)

1. Goto T, Kino H, Hatanaka M, Koshaka M, Aoki H, Imanaka H. FK506: historical perspectives. Transplant Proc 1991;23:2713-2717
2. Fung J, Abu-Elmagd K, Jain A, et al. A randomized trial of primary liver transplantation under immunosuppression with FK 506 vs cyclosporine. Transplant Proc 1991;23:2977-2983
3. The U.S. Multicenter FK506 Liver Study Group A comparison of tacrolimus (FK506) and cyclosporine for immunosuppression in liver transplantation. N Engl J Med 1994;331.1110-1115
4. Fung JJ, Alessiani M, Abu-Elmagd K, et al. Adverse effects associated with the use of FK 506. Transplant Proc 1991;23:3105-3108
5. Eidelman BH, Abu-Elmagd K, Wilson J, et al. Neurologic complications of FK 506. Transplant Proc 1991;23:3175-3178
6. Wallemacq PE, Reding R. FK506 (tacrolimus), a novel immunosuppressant in organ transplantation: clinical, biomedical and analytic aspects. Clin Chem 1993;39:2219-2228
7. Klintmalm GB. FK 506: an update. Clin Transplant 1994,8.207-210
8. Thuluvath PJ, Edwin D, Yue NC, deVilliera C, Hochman S, Klein A. Increased signals seen in globus pallidus in T1-weighted magnetic resonance imaging in cirrhotics are not suggestive of chronic hepatic encephalopathy Hepatology 1995;21:440-442
9. Uchino A, Hasuo K, Natsumoto S, Nasuda K. Cerebral magnetic resonance imaging of liver cirrhosis patients. Clin Imaging 1994;18:123-130
10. Zeneroli ML, Cioni G, Crisi G, Vezzelli C, Ventura E. Globus pallidus alterations and brain atrophy in liver cirrhosis patients with encephalopathy: an MR imaging study. Magn Reson Imaging 1991,9.295-302
11. Inoue E, Hori S, Narumi Y, et al. Portal-systemic encephalopathy. presence of basal ganglia lesions with high signal intensity on MR images. Radiology 1991;179:551-555
12. Venkataramanan R, Jain A, Warty VS, et al Pharmacokinetics of FK506 in transplant patients. Transplant Proc 1991;23:2736-2739
13. Schreiber SL, Crabtree GR. The mechanism of action of cyclosporin A and FK506. Immunol Today 1992;13:136-142
14. Schreiber SL. Chemistry and biology of the immunophilins and their immunosuppressive ligands. Science 1991;251:283-287
15. Liu J, Farmer JD, Lane WS, Friedman J, Weissman I, Schreiber SL. Calcineurin is a common target of cyclophilin-cyclosporin A and FKBP-FK506 complexes Cell 1991;66:807-815
16. deGroen PC, Aksamit AJ, Rakela J, Forbes GS, Krom RAF. Central nervous system toxicity after liver transplantation: the role of cyclosporine and cholesterol. N Engl J Med 1987;317:861-866
17. Singh N, Yu VL, Gayowski T. Central nervous system lesions in adult liver transplant recipients: clinical review with implications for management. Medicine (Baltimore) 1994;73:110-118
18. Estol CJ, Faris AA, Martinez AJ, Ahdab-Barmada M. Central pontine myelinolysis after liver transplantation. Neurology 1989;39:493-498
19. Ferreiro JA, Robert MA, Townsend J, Vinters HV. Neuropathologic findings after liver transplantation. Acta Neuropathol 1992;84:1-14
20. Wsolek ZK, McComb RD, Pfeiffer RF, et al. Pontine and extrapontine myelinolysis following liver transplantation. Transplantation 1989,48 1006-1012
21. Boon AP, Adams DH, Buckels JAC, McMaster P Neuropathological findings in autopsies after liver transplantation. Transplant Proc 1991,23 1471-1472
22. Korogi Y, Takahashi M, Shinzato J, et al. MR findings in two presumed cases of central pontine myelinolysis. AJNR 1993;14:651-654