Activation of GTP formation and high-affinity GTP hydrolysis by mastoparan in various cell membranes: G-protein activation via nucleoside diphosphate kinase, a possible general mechanism of mastoparan action

Biochemical Pharmacology

Volumn 51, Issue 3, 1996, Pages 217-223

  Klinker, Jan F ^a   Laugwitz, Karl Ludwig ^a   Hagelüken, Astrid ^a   Seifert, Roland ^a,b  

^a FREIE UNIVERSITÄT BERLIN   (Germany)

^b STANFORD UNIVERSITY MEDICAL CENTER   (United States)

Author keywords

Cell membranes; G proteins; GTP azidoanilide; GTPase; Mastoparan; Nucleoside diphosphate kinase; Pertussis toxin

Indexed keywords

ENKEPHALIN[2 DEXTRO ALANINE 5 DEXTRO LEUCINE]; GUANINE NUCLEOTIDE BINDING PROTEIN; GUANOSINE TRIPHOSPHATASE; GUANOSINE TRIPHOSPHATE; MASTOPARAN; MASTOPARAN 7; MASTOPARAN DERIVATIVE; NUCLEOSIDE DIPHOSPHATE KINASE; PERTUSSIS TOXIN; PROTEIN SUBUNIT; UNCLASSIFIED DRUG; WASP VENOM;

ANIMAL CELL; ARTICLE; CELL LINE; CELL MEMBRANE; CONTROLLED STUDY; ENZYME ACTIVITY; ERYTHROLEUKEMIA CELL; HAMSTER; HUMAN; HUMAN CELL; HYDROLYSIS; MAST CELL LEUKEMIA; NEUROBLASTOMA CELL; NONHUMAN; PHOTOAFFINITY LABELING; PRIORITY JOURNAL; RAT; SMOOTH MUSCLE FIBER; VAS DEFERENS;

ANIMALS; CELL LINE; CELL MEMBRANE; CRICETINAE; GTP-BINDING PROTEINS; GUANOSINE TRIPHOSPHATE; HUMANS; LEUKEMIA, ERYTHROBLASTIC, ACUTE; NEUROBLASTOMA; NUCLEOSIDE-DIPHOSPHATE KINASE; PEPTIDES; PERTUSSIS TOXIN; RATS; TUMOR CELLS, CULTURED; VIRULENCE FACTORS, BORDETELLA; WASP VENOMS;

EID: 0030062604     PISSN: 00062952     EISSN: None     Source Type: Journal    
DOI: 10.1016/0006-2952(95)02119-1     Document Type: Article

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