Selective inhibition of cyclic AMP-dependent protein kinase by amphiphilic triterpenoids and related compounds

Phytochemistry

Volumn 41, Issue 1, 1996, Pages 55-63

  Wang, Bing Hui ^a   Polya, Gideon M ^a  

^a LA TROBE UNIVERSITY   (Australia)

Author keywords

Cyclic AMP dependent protein kinase; Protein kinase inhibitors; Triterpenoids

Indexed keywords

CYCLIC AMP DEPENDENT PROTEIN KINASE; ENZYME INHIBITOR; EPIDERMAL GROWTH FACTOR RECEPTOR; OLIGOPEPTIDE; TRITERPENE;

AMINO ACID SEQUENCE; ANIMAL; ARTICLE; BRAIN; CHEMISTRY; COMPARATIVE STUDY; DRUG ANTAGONISM; ENZYMOLOGY; KINETICS; METABOLISM; MOLECULAR GENETICS; RAT; STRUCTURE ACTIVITY RELATION; SYNTHESIS;

AMINO ACID SEQUENCE; ANIMALS; BRAIN; CYCLIC AMP-DEPENDENT PROTEIN KINASES; ENZYME INHIBITORS; KINETICS; MOLECULAR SEQUENCE DATA; OLIGOPEPTIDES; RATS; RECEPTOR, EPIDERMAL GROWTH FACTOR; STRUCTURE-ACTIVITY RELATIONSHIP; TRITERPENES;

ANIMALIA;

EID: 0030062263     PISSN: 00319422     EISSN: None     Source Type: Journal    
DOI: 10.1016/0031-9422(95)00583-8     Document Type: Article

References (10)

1. Harborne, J. B. (1988) Introduction to Ecological Biochemistry (3rd edn). Academic Press, London.
2. Harborne, J. B. and Baxter, H. (1993) Phytochemical Dictionary. A Handbook of Bioactive Compounds from Plants. Taylor and Francis, London.
3. Jinsart, W., Ternai, B., Buddhasukh, D. and Polya G. M. (1992) Phytochemistry 31, 3711.
4. Rang, H. P. and Dale, M. M. (1991) Pharmacology (2nd edn). Churchill Livingstone, London.
5. Nogrady, T. (1985) Medicinal Chemistry. A Biochemical Approach. Oxford University Press, Oxford.
6. Jinsart, W., Ternai, B. and Polya, G. M. (1991) Biol. Chem. Hoppe-Seyler 372, 819.
7. Jinsart, W., Ternai, B. and Polya, G. M. (1992) Biol. Chem. Hoppe-Seyler 373, 205.
8. Ferriola, P. C., Cody, V. and Middleton, E. (1989) Biochem. Pharmacol. 38, 1617.
9. Rogers, J. C. and Williams, D. L. (1989) Biochem. Biophys. Res. Commun. 164, 419.
10. Polya, G. M. and Foo, L. Y. (1994) Phytochemistry 35, 1399.