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Volumn 44, Issue 1-3, 1996, Pages 171-181

Induction of protective immunity by aerosol or oral application of candidate vaccines in a dose-controlled pig aerosol infection model

Author keywords

Actinobacillus pleuropneumoniae; Aerosol; Bronchoalveolar lavage; Immunoglobulin; Mucosal immunity; Oral immunization; Pig; Vaccine

Indexed keywords

AEROSOLS; BACTERIA; CONTROLLED DRUG DELIVERY; DRUG DOSAGE; IMMUNIZATION; IMMUNOLOGY; LIVING SYSTEMS STUDIES; PHYSIOLOGICAL MODELS;

EID: 0030062140     PISSN: 01681656     EISSN: None     Source Type: Journal    
DOI: 10.1016/0168-1656(95)00150-6     Document Type: Conference Paper
Times cited : (48)

References (52)
  • 1
    • 0019412005 scopus 로고
    • Bacterial adherence: Adhesin-receptor interactions mediating the attachment of bacteria to mucosal surfaces
    • Beachey, E.H. (1981) Bacterial adherence: adhesin-receptor interactions mediating the attachment of bacteria to mucosal surfaces. J. Infect. Dis. 143, 325-345.
    • (1981) J. Infect. Dis. , vol.143 , pp. 325-345
    • Beachey, E.H.1
  • 2
    • 0025718806 scopus 로고
    • Polymerase chain reaction-gene probe detection of microorganisms by using filter-concentrated samples
    • Bej, A.K., Mahbubani, M.H., Dicesare, J.L. and Atlas, R.M. (1991) Polymerase chain reaction-gene probe detection of microorganisms by using filter-concentrated samples. Appl. Environ. Microbiol. 57, 3529-3534.
    • (1991) Appl. Environ. Microbiol. , vol.57 , pp. 3529-3534
    • Bej, A.K.1    Mahbubani, M.H.2    Dicesare, J.L.3    Atlas, R.M.4
  • 3
    • 0022159646 scopus 로고
    • Quantitative morphology of peracute pulmonary lesions in swine induced by Haemophilus pleuropneumoniae
    • Bertram, T.A. (1985) Quantitative morphology of peracute pulmonary lesions in swine induced by Haemophilus pleuropneumoniae. Vet. Pathol. 22, 598-609.
    • (1985) Vet. Pathol. , vol.22 , pp. 598-609
    • Bertram, T.A.1
  • 4
    • 0017440263 scopus 로고
    • Cultural and biochemical criteria for the identification of haemophilus spp from swine
    • Biberstein, E.L., Gunnarsson, A. and Hurvell, B. (1977) Cultural and biochemical criteria for the identification of haemophilus spp from swine. Am. J. Vet. Res. 38, 7-11.
    • (1977) Am. J. Vet. Res. , vol.38 , pp. 7-11
    • Biberstein, E.L.1    Gunnarsson, A.2    Hurvell, B.3
  • 5
    • 0026327014 scopus 로고
    • Protective local and systemic antibody responses of swine exposed to an aerosol of Actinobacillus pleuropneumoniae serotype 1
    • Bossé, J.T., Johnson, R.P., Nemec, M. and Rosendal, S. (1992) Protective local and systemic antibody responses of swine exposed to an aerosol of Actinobacillus pleuropneumoniae serotype 1. Infect. Immun. 60, 479-484.
    • (1992) Infect. Immun. , vol.60 , pp. 479-484
    • Bossé, J.T.1    Johnson, R.P.2    Nemec, M.3    Rosendal, S.4
  • 6
    • 0017249009 scopus 로고
    • Pulmonary distribution of particle given by intratracheal instillation or by aerosol inhalation
    • Brain, J.D., Knudson, D.E., Sorokin, S.P. and Davis, M.A. (1976) Pulmonary distribution of particle given by intratracheal instillation or by aerosol inhalation. Environ. Res. 11, 13-33.
    • (1976) Environ. Res. , vol.11 , pp. 13-33
    • Brain, J.D.1    Knudson, D.E.2    Sorokin, S.P.3    Davis, M.A.4
  • 7
    • 0025078306 scopus 로고
    • Toxic risks from inhalation of bacterial endotoxin
    • Burrell, R. and Yeh, S.H. (1990) Toxic risks from inhalation of bacterial endotoxin. Br. J. Ind. Med. 47, 688-691.
    • (1990) Br. J. Ind. Med. , vol.47 , pp. 688-691
    • Burrell, R.1    Yeh, S.H.2
  • 8
    • 0014771113 scopus 로고
    • Aerosol survival of Escherichia coli B disseminated from the dry state
    • Cox, C.S. (1970) Aerosol survival of Escherichia coli B disseminated from the dry state. Appl. Microbiol. 19, 604-607.
    • (1970) Appl. Microbiol. , vol.19 , pp. 604-607
    • Cox, C.S.1
  • 9
    • 0015024022 scopus 로고
    • Aerosol survival of Pasteurella tularensis disseminated from the wet and dry states
    • Cox, C.S. (1971) Aerosol survival of Pasteurella tularensis disseminated from the wet and dry states. Appl, Microbiol. 21, 482-486.
    • (1971) Appl, Microbiol. , vol.21 , pp. 482-486
    • Cox, C.S.1
  • 10
    • 0026466822 scopus 로고
    • Cellular changes in the bronchoalveolar lavage (BAL) of pigs, following immunization by the enteral or respiratory route
    • Delventhal, S., Hensel, A., Petzoldt, K. and Pabst, R. (1992a) Cellular changes in the bronchoalveolar lavage (BAL) of pigs, following immunization by the enteral or respiratory route. Clin. Exp. Immunol. 90, 223-227.
    • (1992) Clin. Exp. Immunol. , vol.90 , pp. 223-227
    • Delventhal, S.1    Hensel, A.2    Petzoldt, K.3    Pabst, R.4
  • 11
    • 0026749787 scopus 로고
    • Effects of microbial stimulation on the number, size and activity of bronchus-associated lymphoid tissue (BALT) in the pig
    • Delventhal, S., Hensel, A., Petzoldt K. and Pabst, R. (1992b) Effects of microbial stimulation on the number, size and activity of bronchus-associated lymphoid tissue (BALT) in the pig. Int. J. Exp. Pathol. 73, 351-357.
    • (1992) Int. J. Exp. Pathol. , vol.73 , pp. 351-357
    • Delventhal, S.1    Hensel, A.2    Petzoldt, K.3    Pabst, R.4
  • 12
    • 0022994809 scopus 로고
    • Immune responses to the lipopolysaccharides and capsular polysaccharides of Haemophilus pleuropneumoniae in convalescent and immunized pigs
    • Fenwick, B.W. and Osburn, B.I. (1986) Immune responses to the lipopolysaccharides and capsular polysaccharides of Haemophilus pleuropneumoniae in convalescent and immunized pigs. Infect. Immun. 54, 575-582.
    • (1986) Infect. Immun. , vol.54 , pp. 575-582
    • Fenwick, B.W.1    Osburn, B.I.2
  • 13
    • 38249041937 scopus 로고
    • Radiolabeling of Erysipelothrix rhusiopathiae bacteria for inhalation studies in piglets
    • Gerlach, G.-F., Creutzig, H., Franz, B. and Petzoldt, K. (1986) Radiolabeling of Erysipelothrix rhusiopathiae bacteria for inhalation studies in piglets. J. Aerosol Sci. 17, 337-339.
    • (1986) J. Aerosol Sci. , vol.17 , pp. 337-339
    • Gerlach, G.-F.1    Creutzig, H.2    Franz, B.3    Petzoldt, K.4
  • 14
    • 0027172535 scopus 로고
    • A porcine aerosol infection model for studying dose dependent effects caused by Actinobacillus pleuropneumoniae bacteria
    • Hensel, A., Windt, H., Stockhofe-Zurwieden, N., Lödding, H., Koch, W. and Petzoldt, K. (1993) A porcine aerosol infection model for studying dose dependent effects caused by Actinobacillus pleuropneumoniae bacteria. J. Aerosol Med. 6, 73-88.
    • (1993) J. Aerosol Med. , vol.6 , pp. 73-88
    • Hensel, A.1    Windt, H.2    Stockhofe-Zurwieden, N.3    Lödding, H.4    Koch, W.5    Petzoldt, K.6
  • 15
    • 0028010589 scopus 로고
    • Influence of serum and glucose additives on survival of Actinobacillus pleuropneumoniae aerosolized from the freeze-dried state
    • Hensel, A. (1994a) Influence of serum and glucose additives on survival of Actinobacillus pleuropneumoniae aerosolized from the freeze-dried state. Appl. Environ. Microbiol. 60, 2155-2157
    • (1994) Appl. Environ. Microbiol. , vol.60 , pp. 2155-2157
    • Hensel, A.1
  • 17
    • 0028710330 scopus 로고
    • Prevalence of aerobic bacteria in bronchoalveolar lavage fluids (BALF) of healthy pigs
    • Hensel, A., Ganter, M., Kipper, S., Krehon, S., Wittenbrink, M.M. and Petzoldt, K. (1994c) Prevalence of aerobic bacteria in bronchoalveolar lavage fluids (BALF) of healthy pigs. Am. J. Vet. Res., 55, 1697-1702.
    • (1994) Am. J. Vet. Res. , vol.55 , pp. 1697-1702
    • Hensel, A.1    Ganter, M.2    Kipper, S.3    Krehon, S.4    Wittenbrink, M.M.5    Petzoldt, K.6
  • 18
    • 0028360040 scopus 로고
    • Oral and aerosol immunization with viable or inactivated Actinobacillus pleuropneumoniae bacteria: Antibody response to capsular polysaccharides in bronchoalveolar lavage fluids (BALF) and sera of pigs
    • Hensel, A., Pabst, R., Bunka, S. and Petzoldt, K. (1994d), Oral and aerosol immunization with viable or inactivated Actinobacillus pleuropneumoniae bacteria: antibody response to capsular polysaccharides in bronchoalveolar lavage fluids (BALF) and sera of pigs. Clin. Exp. Immunol. 96, 91-97.
    • (1994) Clin. Exp. Immunol. , vol.96 , pp. 91-97
    • Hensel, A.1    Pabst, R.2    Bunka, S.3    Petzoldt, K.4
  • 19
    • 0343951842 scopus 로고
    • Aerosol application of viable or inactivated Actinobacillus pleuropneumoniae serotype 9 to pigs induces antibodies in bronchoalveolar lining fluids and serum and protects against homologous aerosol challenge
    • in press
    • Hensel, A., Stockhofe-Zurwieden, N., Ganter, M. and Petzoldt, K. (1995a) Aerosol application of viable or inactivated Actinobacillus pleuropneumoniae serotype 9 to pigs induces antibodies in bronchoalveolar lining fluids and serum and protects against homologous aerosol challenge. Vet. Microbiol., in press.
    • (1995) Vet. Microbiol.
    • Hensel, A.1    Stockhofe-Zurwieden, N.2    Ganter, M.3    Petzoldt, K.4
  • 20
    • 0029154978 scopus 로고
    • Oral immunization of pigs with viable or inactivated Actinobacillus pleuropneumoniae serotype 9 induces pulmonary and systemic antibodies and protects against homologous aerosol challenge
    • Hensel, A., Stockhofe-Zurwieden, N. and Petzoldt, K. (1995b) Oral immunization of pigs with viable or inactivated Actinobacillus pleuropneumoniae serotype 9 induces pulmonary and systemic antibodies and protects against homologous aerosol challenge. Infect. Immun. 63, 3048-3053.
    • (1995) Infect. Immun. , vol.63 , pp. 3048-3053
    • Hensel, A.1    Stockhofe-Zurwieden, N.2    Petzoldt, K.3
  • 21
    • 0026284752 scopus 로고
    • Mucosal immunity and vaccination
    • Holmgren, J. (1991) Mucosal immunity and vaccination. FEMS Microbiol. Immunol. 89, 1-10.
    • (1991) FEMS Microbiol. Immunol. , vol.89 , pp. 1-10
    • Holmgren, J.1
  • 22
    • 0026249158 scopus 로고
    • Virulence properties of Actinobacillus pleuropneumoniae
    • Inzana, T.J. (1991). Virulence properties of Actinobacillus pleuropneumoniae. Microbial Pathogenesis 11, 305-316.
    • (1991) Microbial Pathogenesis , vol.11 , pp. 305-316
    • Inzana, T.J.1
  • 23
    • 0026065998 scopus 로고
    • Adherence of Actinobacillus pleuropneumoniae to porcine tracheal epithelial cells and frozen lung sections
    • Jacques, M., Belanger, M., Roy, G. and Foiry, B. (1991) Adherence of Actinobacillus pleuropneumoniae to porcine tracheal epithelial cells and frozen lung sections. Vet. Microbiol. 27, 133-143.
    • (1991) Vet. Microbiol. , vol.27 , pp. 133-143
    • Jacques, M.1    Belanger, M.2    Roy, G.3    Foiry, B.4
  • 25
    • 0017183413 scopus 로고
    • The hemolytic activity of Haemophilus species
    • Kilian, M. (1976) The hemolytic activity of Haemophilus species. Acta Pathol. Microbiol. Scand. Sect. B 84, 339-341.
    • (1976) Acta Pathol. Microbiol. Scand. Sect. B , vol.84 , pp. 339-341
    • Kilian, M.1
  • 27
    • 0023302676 scopus 로고
    • Sequential study of lesion development in experimental haemophilus pleuropneumonia
    • Liggett, A.D. and Harrison, L.R. (1987) Sequential study of lesion development in experimental haemophilus pleuropneumonia. Res. Vet. Sci. 42, 204-221.
    • (1987) Res. Vet. Sci. , vol.42 , pp. 204-221
    • Liggett, A.D.1    Harrison, L.R.2
  • 28
    • 0027361261 scopus 로고
    • Protective immunity following immunisation of pigs with aerosol of Actinobacillus pleuropneumoniae serotype 2
    • Loftager, M.K., Eriksen, L., Aasted, B. and Nielsen, R. (1994) Protective immunity following immunisation of pigs with aerosol of Actinobacillus pleuropneumoniae serotype 2. Res. Vet. Sci. 55, 281-286.
    • (1994) Res. Vet. Sci. , vol.55 , pp. 281-286
    • Loftager, M.K.1    Eriksen, L.2    Aasted, B.3    Nielsen, R.4
  • 29
    • 0008903012 scopus 로고
    • Actinobacillus (Haemophilus) pleuropneumoniae symposium, a review
    • Lynch, J A. and Lariviére, S. (1988) Actinobacillus (Haemophilus) pleuropneumoniae symposium, a review. Can. Vet. J. 29, 571.
    • (1988) Can. Vet. J. , vol.29 , pp. 571
    • Lynch, J.A.1    Lariviére, S.2
  • 30
    • 0023680550 scopus 로고
    • Prevention and control of Actinobacillus (Haemophilus) pleuropneumoniae infection in swine: A review
    • MacInnes, J.I. and Rosendal, S. (1988) Prevention and control of Actinobacillus (Haemophilus) pleuropneumoniae infection in swine: a review. Can. J. Vet. 29, 572-574.
    • (1988) Can. J. Vet. , vol.29 , pp. 572-574
    • MacInnes, J.I.1    Rosendal, S.2
  • 31
    • 0001873715 scopus 로고
    • Recovery of freeze-dried cells from dry powder aerosols
    • Andrew, M.H.E. and Russell, A.D. (Eds.), Academic Press, Inc., New York
    • Mackey, E.Y. (1984) Recovery of freeze-dried cells from dry powder aerosols. In: Andrew, M.H.E. and Russell, A.D. (Eds.), The Revival of Injured Microbes. Academic Press, Inc., New York, pp. 45-75.
    • (1984) The Revival of Injured Microbes , pp. 45-75
    • Mackey, E.Y.1
  • 32
    • 0023243066 scopus 로고
    • The common mucosal immune system and current strategies for induction of immune responses in external secretions
    • Mestecky, J. (1987) The common mucosal immune system and current strategies for induction of immune responses in external secretions. J. Clin. Immunol. 7, 265-276.
    • (1987) J. Clin. Immunol. , vol.7 , pp. 265-276
    • Mestecky, J.1
  • 33
    • 85030195764 scopus 로고
    • Zur Haemophilus-pleuopneumonie beim Schwein, II. Eine kontagiöse Krankheit von wirtschaftlicher Bedeutung
    • Nicolet, J., König, H. and Scholl, E. (1969) Zur Haemophilus-pleuopneumonie beim Schwein, II. Eine kontagiöse Krankheit von wirtschaftlicher Bedeutung. Schweiz. Arch. Tierheilk. 111, 116-174.
    • (1969) Schweiz. Arch. Tierheilk. , vol.111 , pp. 116-174
    • Nicolet, J.1    König, H.2    Scholl, E.3
  • 34
    • 0017554209 scopus 로고
    • Pleuropneumonia of swine caused by Haemophilus parahaemolyticus. A study of the epidemiology of infection
    • Nielsen, R. and Mandrup, M. (1977) Pleuropneumonia of swine caused by Haemophilus parahaemolyticus. A study of the epidemiology of infection. Nord. Vet. Med. 29, 465-473.
    • (1977) Nord. Vet. Med. , vol.29 , pp. 465-473
    • Nielsen, R.1    Mandrup, M.2
  • 35
    • 0021455059 scopus 로고
    • Haemophilus pleuropneumoniae serotypes: Cross protection experiments
    • Nielsen, R. (1984) Haemophilus pleuropneumoniae serotypes: cross protection experiments. Nord. Vet. Med, 36, 221-234.
    • (1984) Nord. Vet. Med , vol.36 , pp. 221-234
    • Nielsen, R.1
  • 36
    • 0026101391 scopus 로고
    • Blocking enzyme-linked immunosorbent assay for detection of antibod-ies to Actinobacillus pleuropneumoniae serotype 2
    • Nielsen, R., Plambeck, T. and Foged, N.T. (1991) Blocking enzyme-linked immunosorbent assay for detection of antibod-ies to Actinobacillus pleuropneumoniae serotype 2. J. Clin. Microbiol. 29, 794-797.
    • (1991) J. Clin. Microbiol. , vol.29 , pp. 794-797
    • Nielsen, R.1    Plambeck, T.2    Foged, N.T.3
  • 37
    • 0029096242 scopus 로고
    • Lymphocyte subsets in BAL after exposition to Actinobacillus pleuropneumoniae in pigs previously immunized orally or by aerosol
    • Pabst, R., Delventhal, S., Gebert, A., Mensel, A. and Petzoldt, K. (1995) Lymphocyte subsets in BAL after exposition to Actinobacillus pleuropneumoniae in pigs previously immunized orally or by aerosol. Lung 173, 233-241.
    • (1995) Lung , vol.173 , pp. 233-241
    • Pabst, R.1    Delventhal, S.2    Gebert, A.3    Mensel, A.4    Petzoldt, K.5
  • 38
    • 0020712910 scopus 로고
    • A comfortable, minimum stress method of restraint for Yucatan miniature swine
    • Panepinto, L.M., Phillips, R.W., Norden, S., Pryor, P.C. and Cox, R. (1983) A comfortable, minimum stress method of restraint for Yucatan miniature swine. Lab. Anim. Sci. 3, 95-97.
    • (1983) Lab. Anim. Sci. , vol.3 , pp. 95-97
    • Panepinto, L.M.1    Phillips, R.W.2    Norden, S.3    Pryor, P.C.4    Cox, R.5
  • 39
    • 0343951831 scopus 로고
    • Haemophilus pleuropneumoniae infections in pigs
    • Rijsing, H.-J. (1981) Haemophilus pleuropneumoniae infections in pigs. Proc. Int. Pig Vet. Sec. 9, 77-83.
    • (1981) Proc. Int. Pig Vet. Sec. , vol.9 , pp. 77-83
    • Rijsing, H.-J.1
  • 40
    • 0026734528 scopus 로고
    • Immunization of pigs against Actinobacillus pleuropneumoniae with two recombinant protein preparations
    • Rossi-Campos, A., Anderson, C., Gerlach, G.F., Klashinsky, S., Potter, A.A. and Wilson, P.J. (1992) Immunization of pigs against Actinobacillus pleuropneumoniae with two recombinant protein preparations. Vaccine 10, 512-518.
    • (1992) Vaccine , vol.10 , pp. 512-518
    • Rossi-Campos, A.1    Anderson, C.2    Gerlach, G.F.3    Klashinsky, S.4    Potter, A.A.5    Wilson, P.J.6
  • 41
    • 0021104150 scopus 로고
    • Haemophilus pleuropneumoniae infection in swine: A review
    • Sebunya, T.N.K. and Saunders, J.R. (1983) Haemophilus pleuropneumoniae infection in swine: a review. JAVMA 182, 1331-1337.
    • (1983) JAVMA , vol.182 , pp. 1331-1337
    • Sebunya, T.N.K.1    Saunders, J.R.2
  • 42
    • 0020196272 scopus 로고
    • Pulmonary clearance of Haemophilus pleuropneumoniae and Serratia marcescens in mice
    • Sebunya, T.N.K. and Saunders, J.R. (1982) Pulmonary clearance of Haemophilus pleuropneumoniae and Serratia marcescens in mice. Am. J. Vet. Res. 43, 1799-1801.
    • (1982) Am. J. Vet. Res. , vol.43 , pp. 1799-1801
    • Sebunya, T.N.K.1    Saunders, J.R.2
  • 43
    • 0020658001 scopus 로고
    • Dose reponse relationship of Haemophilus pleuropneumoniae aerosols in pigs
    • Sebunya, T.N.K., Saunders, J.R. and Osborne, A.D. (1983) Dose reponse relationship of Haemophilus pleuropneumoniae aerosols in pigs. Can. J. Comp. Med. 47, 54-56.
    • (1983) Can. J. Comp. Med. , vol.47 , pp. 54-56
    • Sebunya, T.N.K.1    Saunders, J.R.2    Osborne, A.D.3
  • 44
    • 78651144803 scopus 로고
    • Porcine contagious pleuropneumonia. I. Experimental transmission, etiology and pathology
    • Shope, R.E. (1964) Porcine contagious pleuropneumonia. I. Experimental transmission, etiology and pathology. J. Exp. Med. 119, 357-368.
    • (1964) J. Exp. Med. , vol.119 , pp. 357-368
    • Shope, R.E.1
  • 47
    • 0026586661 scopus 로고
    • Survival of toxigenic Pasteurella multocida in aerosols and aqueous liquids
    • Thomson, C.M.A., Chanter, N. and Wathes, C.M. (1992) Survival of toxigenic Pasteurella multocida in aerosols and aqueous liquids. Appl. Environ. Microbiol, 58, 932-936.
    • (1992) Appl. Environ. Microbiol , vol.58 , pp. 932-936
    • Thomson, C.M.A.1    Chanter, N.2    Wathes, C.M.3
  • 49
    • 0024650917 scopus 로고
    • A method for bronchoalveolar lavage in live pigs
    • van Leengoed, L.A.M.G. and Kamp, E.M. (1989a) A method for bronchoalveolar lavage in live pigs. Vet. Quart. 11, 65-72.
    • (1989) Vet. Quart. , vol.11 , pp. 65-72
    • Van Leengoed, L.A.M.G.1    Kamp, E.M.2
  • 50
    • 0024824401 scopus 로고
    • Endobronchial inoculation of various doses of Actinobacillus (Haemophilus) pleuropneumoniae in pigs
    • van Leengoed, L.A.M.G. and Kamp, E.M. (1989b) Endobronchial inoculation of various doses of Actinobacillus (Haemophilus) pleuropneumoniae in pigs. Am. J. Vet. Res. 50, 2054-2059.
    • (1989) Am. J. Vet. Res. , vol.50 , pp. 2054-2059
    • Van Leengoed, L.A.M.G.1    Kamp, E.M.2
  • 51
    • 0024636177 scopus 로고
    • Haemophilux pleuropneumoniae in pigs: A review
    • Veary, C.M. (1989) Haemophilux pleuropneumoniae in pigs: a review. Tydskr. S. Afr. Vet. Ver. 60, 56-61.
    • (1989) Tydskr. S. Afr. Vet. Ver. , vol.60 , pp. 56-61
    • Veary, C.M.1
  • 52
    • 0020443542 scopus 로고
    • Respiratory tract immune response to microbial pathogens
    • Wilkie, B.N. (1982) Respiratory tract immune response to microbial pathogens. J. Am. Vet. Med. Assoc. 181, 1074-1079.
    • (1982) J. Am. Vet. Med. Assoc. , vol.181 , pp. 1074-1079
    • Wilkie, B.N.1


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