Evidence that specificity of microhelix charging by a class I tRNA synthetase occurs in the transition state of catalysis

Biochemistry

Volumn 35, Issue 2, 1996, Pages 608-615

  Gale, Andrew J ^a   Shi, Jian Ping ^a,b   Schimmel, Paul ^a  

^a MASSACHUSETTS INSTITUTE OF TECHNOLOGY   (United States)

^b CUBIST PHARMACEUTICALS INC   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AMINO ACID TRANSFER RNA LIGASE; BACTERIAL ENZYME; TRANSFER RNA;

ARTICLE; CATALYSIS; ENZYME ACTIVITY; ENZYME ANALYSIS; ENZYME SPECIFICITY; ENZYME STRUCTURE; ESCHERICHIA COLI; NONHUMAN; PRIORITY JOURNAL; PROTEIN NUCLEIC ACID INTERACTION;

ANTICODON; BASE SEQUENCE; BINDING SITES; BINDING, COMPETITIVE; CATALYSIS; ESCHERICHIA COLI; KINETICS; METHIONINE-TRNA LIGASE; MOLECULAR SEQUENCE DATA; MUTAGENESIS, SITE-DIRECTED; NUCLEIC ACID CONFORMATION; RNA, BACTERIAL; RNA, TRANSFER, MET; SUBSTRATE SPECIFICITY;

BACTERIA (MICROORGANISMS); ESCHERICHIA COLI;

EID: 0030061945     PISSN: 00062960     EISSN: None     Source Type: Journal    
DOI: 10.1021/bi9520904     Document Type: Article

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