Prostaglandin E2 control of T cell cytokine production is functionally related to the reduced lymphocyte proliferation in atopic dermatitis

Journal of Allergy and Clinical Immunology

Volumn 97, Issue 1 I, 1996, Pages 85-94

  Chan, Sai ^a   Henderson Jr , William R ^b   Li, Shi Hua ^a   Hanifin, Jon M ^a,c  

^a OREGON HEALTH AND SCIENCE UNIVERSITY   (United States)

^b UNIVERSITY OF WASHINGTON   (United States)

^c Department of Dermatology ^*  (United States)

Author keywords

atopic dermatitis; cytokine; proliferation; Prostaglandin E2; T cell

Indexed keywords

GAMMA INTERFERON; INTERLEUKIN 4; LEUKOTRIENE; PHYTOHEMAGGLUTININ; PROSTAGLANDIN E2;

ARTICLE; ATOPIC DERMATITIS; GENE EXPRESSION; HUMAN; HUMAN CELL; IMMUNE RESPONSE; IMMUNOREGULATION; LYMPHOCYTE ACTIVATION; LYMPHOCYTE PROLIFERATION; PRIORITY JOURNAL; PROSTAGLANDIN RELEASE; ADULT; BIOSYNTHESIS; CELL CULTURE; CELL DIVISION; DRUG EFFECT; IMMUNOLOGY; PATHOLOGY; T LYMPHOCYTE;

ADULT; CELL DIVISION; CELLS, CULTURED; DERMATITIS, ATOPIC; DINOPROSTONE; HUMANS; INTERFERON TYPE II; INTERLEUKIN-4; T-LYMPHOCYTES;

EID: 0030060526     PISSN: 00916749     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0091-6749(96)70286-5     Document Type: Article

References (27)

1. Lobitz WC Jr, Honeyman JF, Winkler MW. Suppressed cell-mediated immunity in two adults with atopic dermatitis. Br J Dermatol 1972;86:317-28.
2. McGeady SJ, Buckley RH. Depression of cell-mediated immunity in atopic eczema. J ALLERGY CLIN IMMUNOL 1975;56:393-406.
3. Strannegärd I-L, Lindholm L, Strannegärd Ö. T lymphocytes in atopic children. Int Arch Allergy Appl Immunol 1976;50:684.
4. Elliott ST, Hanifin JM. Lymphocyte response to phytohemagglutinin in atopic dermatitis. Enhancement after in vitro culture. Arch Dermatol 1979;115:1424-6.
5. 2 inhibits production of Th-1 lymphokines but not of Th-2 lymphokines. J Immunol 1991;146:108-13.
6. Phipps RP, Stein SH, Roper RL. A new view of prostaglandin E regulation of the immune response. Immunology Today 1991;12:349-52.
7. Jakob T, Hudspith BN, Latchman YE, Rycroft R. Brostoff J. Depressed lymphocyte transformation and the role of prostaglandins in atopic dermatitis. Clin Exp Immunol 1990;79:380-4.
8. 2 regulation of cytokine production in atopic dermatitis. J Immunol 1993;151:3345-52.
9. Hanifin JM, Rajka G. Diagnostic features of atopic dermatitis. Acta Derm Venereol Suppl (Stockh) 1980;92:44-7.
10. Chan SC, Reifsnyder D, Beavo JA, Hanifin JM. Immunochemical characterization of the distinct monocyte cyclic AMP-phosphodiesterase from patients with atopic dermatitis. J ALLERGY CLIN IMMUNOL 1993;91:1179-88.
11. Holden CA, Chan S, Hanifin JM. Monocyte localization of elevated cAMP phosphodiesterase activity in atopic dermatitis. J Invest Dermatol 1986;87:372.
12. Chan SC, Li S-H, Hanifin JM. Increased interleukin 4 production by atopic mononuclear leukocytes correlates with increased cyclic AMP-PDE activity and is reversible by PDE inhibition. J Invest Dermatol 1993;100:681-4.
13. Jaffe BM, Behrman HR. Prostaglandins E, A, and F. In: Jaffe BM, Behrman HR, editors. Hormone radioimmunoassay. New York: Academic Press, 1974:19.
14. Geissler FT, Kuzan FB, Faustman EM, Henderson WR Jr. Lipid mediator production by post-implantation rat embryos in vitro. Prostaglandins 1989;38:145.
15. Li S-H, Chan SC, Kramer SM, Hanifin JM. Modulation of leukocyte cyclic AMP phosphodiesterase activity by recombinant interferon-gamma: evidence for a differential effect on atopic monocytes. J Interferon Res 1993;13:197-202.
16. Mizoguchi M, Furusawa S, Okitsu S, Yoshino K. Macrophage-derived interleukin 1 activity in atopic dermatitis. J Invest Dermatol 1985;84:303.
17. Kapp A, Kirnbauer R, Luger TA, Schöpf E. Altered production of immuno-modulating cytokines in patients with atopic dermatitis. Acta Derm Venereol Suppl (Stockh) 1989;144:97-9.
18. Räsanen L, Reunala T. Langerhans' cell antigen presentation and interleukin-1 production in atopic dermatitis. Acta Derm Venereol Suppl (Stockh) 1989;(suppl 144):64-6.
19. Thestrup-Pedersen K, Larsen CS, Zachariae C, Kristensen M, Beleuran B, Larsen CG. Interleukin release from peripheral blood mononuclear cells and soluble interleukin-2 receptors in serum from patients with atopic dermatitis. Immunological and pharmacological aspects of atopic and contact eczema. In: Czernielewski JM, editor. Pharmacology and the skin. Karger, Switzerland: Basel, 1991;4:188.
20. Reinhold U, Wehrmann W, Kukel S, Kreysel HW. Evidence that defective interferon-gamma production in atopic dermatitis patients is due to intrinsic abnormalities. Clin Exp Immunol 1990;79:374.
21. Jujo K, Renz H, Abe J, Gelfand EW, Leung DYM. Decreased interferon-gamma and increased interleukin 4 production in atopic dermatitis promotes IgE synthesis. J ALLERGY CLIN IMMUNOL 1992;90:323-31.
22. Hanifin JM, Schneider LC, Leung DYM, et al. Recombinant interferon-gamma therapy for atopic dermatitis. J Am Acad Dermatol 1993;28:189-97.
23. van Reijsen FC, Bruynzeel-Koomen CAFM, Kalthoff FS, et al. Skin derived aeroallergen-speciflc T cell clones of Th2 phenotype in patients with atopic dermatitis. J ALLERGY CLIN IMMUNOL 1992;90:184-92.
24. Gajewski TF, Fitch FW. Anti-proliferative effect of IFN-γ in immune regulation, I: IFN-γ inhibits the proliferation of Th2 but not Th1 murine helper T lymphocyte clones. J Immunol 1988;140:4245-52.
25. 2 differentially modulates cytokine secretion profiles of human T helper lymphocytes. J Immunol 1993;150:5321-9.
26. Peleman R, Wu J, Fargeas C, Delespesse G. Recombinant interleukin 4 suppresses the production of interferon-γ by human mononuclear cells. J Exp Med 1989;170:1751.
27. Vercelli D, Jabara HH, Lauener RP, Geha RS. IL-4 inhibits the synthesis of IFN-γ and induces the synthesis of IgE in human mixed lymphocyte cultures. J Immunol 1990; 144:570-3.