-
1
-
-
0002990050
-
Beta-lactam antibiotics: Structure-activity relationships
-
(Eds. Demain AL and Solomon NA), Springer, Berlin
-
Hoover JRE, Beta-lactam antibiotics: Structure-activity relationships. In: Handbook of Experimental Pharmacology (Eds. Demain AL and Solomon NA), Vol. 67/II. pp. 119-245. Springer, Berlin, 1983.
-
(1983)
Handbook of Experimental Pharmacology
, vol.67
, Issue.2
, pp. 119-245
-
-
Hoover, J.R.E.1
-
2
-
-
0019277757
-
Cephalosporin nephrotoxicity. Transport, cytotoxicity and mitochondrial toxicity to cephaloglycin
-
Tune BM and Fravert D, Cephalosporin nephrotoxicity. Transport, cytotoxicity and mitochondrial toxicity to cephaloglycin. J Pharmacol Exp Ther 215: 186-190, 1980.
-
(1980)
J Pharmacol Exp Ther
, vol.215
, pp. 186-190
-
-
Tune, B.M.1
Fravert, D.2
-
3
-
-
0000017649
-
The nephrotoxicity of cephalosporin antibiotics. Structure-activity relationships
-
Tune BM, The nephrotoxicity of cephalosporin antibiotics. Structure-activity relationships. Comments Toxicol 1: 145-170, 1986.
-
(1986)
Comments Toxicol
, vol.1
, pp. 145-170
-
-
Tune, B.M.1
-
4
-
-
0016372484
-
Substituent effects upon the base hydrolysis of penicillins and cephalosporins. Competitive intramolecular nucleophilic amino attack in cephalosporins
-
Indelicato JM, Norvilas TT, Pfeiffer RR, Wheeler WJ and Wilham WL, Substituent effects upon the base hydrolysis of penicillins and cephalosporins. Competitive intramolecular nucleophilic amino attack in cephalosporins. J Med Chem 17: 523-527, 1974.
-
(1974)
J Med Chem
, vol.17
, pp. 523-527
-
-
Indelicato, J.M.1
Norvilas, T.T.2
Pfeiffer, R.R.3
Wheeler, W.J.4
Wilham, W.L.5
-
5
-
-
0017085194
-
Comparative stability of cephalosporins in aqueous solution: Kinetics and mechanisms of degradation
-
Yamana T and Tsuji A, Comparative stability of cephalosporins in aqueous solution: Kinetics and mechanisms of degradation. J Pharrn Sci 65: 1563-1574, 1976.
-
(1976)
J Pharrn Sci
, vol.65
, pp. 1563-1574
-
-
Yamana, T.1
Tsuji, A.2
-
6
-
-
0017409143
-
Hydrolysis of 3-chloro-3-cephems. Intramolecular nucleophilic attack in cefaclor
-
Indelicato JM, Dinner A, Peters LR and Wilham WL, Hydrolysis of 3-chloro-3-cephems. Intramolecular nucleophilic attack in cefaclor. J Med Chem 20: 961-963, 1977.
-
(1977)
J Med Chem
, vol.20
, pp. 961-963
-
-
Indelicato, J.M.1
Dinner, A.2
Peters, L.R.3
Wilham, W.L.4
-
7
-
-
0023923956
-
The acylating potential of γ-lactam antibacterials: Base hydrolysis of bicyclic pyrazolidinones
-
Indelicato JM and Pasini CE, The acylating potential of γ-lactam antibacterials: Base hydrolysis of bicyclic pyrazolidinones. J Med Chem 31: 1227-1230, 1988.
-
(1988)
J Med Chem
, vol.31
, pp. 1227-1230
-
-
Indelicato, J.M.1
Pasini, C.E.2
-
8
-
-
0025370772
-
Comparative reactivity of 1-carba-1-dethiacephalosporins with cephalosporins
-
Blaszczak L, Brown R, Cook G, Hornback W, Hoying R, Indelicato J, Jordan C, Katner A, Kinnick M, McDonald JI, Morin JM, Munroe JE and Pasini CE, Comparative reactivity of 1-carba-1-dethiacephalosporins with cephalosporins. J Med Chem 33: 1656-1662, 1990.
-
(1990)
J Med Chem
, vol.33
, pp. 1656-1662
-
-
Blaszczak, L.1
Brown, R.2
Cook, G.3
Hornback, W.4
Hoying, R.5
Indelicato, J.6
Jordan, C.7
Katner, A.8
Kinnick, M.9
McDonald, J.I.10
Morin, J.M.11
Munroe, J.E.12
Pasini, C.E.13
-
9
-
-
0026601868
-
Pharmaceutical properties of loracarbef: The remarkable solution stability of an oral 1-carba-1-dethiacephalosporin antibiotic
-
Pasini C and Indelicato J, Pharmaceutical properties of loracarbef: The remarkable solution stability of an oral 1-carba-1-dethiacephalosporin antibiotic. Pharm Res 9: 250-254, 1992.
-
(1992)
Pharm Res
, vol.9
, pp. 250-254
-
-
Pasini, C.1
Indelicato, J.2
-
10
-
-
0000919077
-
The nephrotoxicity of beta-lactam antibiotics
-
(Eds. Hook JB and Goldstein RS), Raven Press, New York
-
Tune BM, The nephrotoxicity of beta-lactam antibiotics. In: Toxicology of the Kidney (Eds. Hook JB and Goldstein RS), pp. 257-281. Raven Press, New York, 1993.
-
(1993)
Toxicology of the Kidney
, pp. 257-281
-
-
Tune, B.M.1
-
11
-
-
0020972419
-
Penicillin binding proteins and the mechanism of action of beta-lactam antibiotics
-
Waxman DJ and Strominger JL, Penicillin binding proteins and the mechanism of action of beta-lactam antibiotics. Annu Rev Biochem 52: 825-869, 1983.
-
(1983)
Annu Rev Biochem
, vol.52
, pp. 825-869
-
-
Waxman, D.J.1
Strominger, J.L.2
-
12
-
-
0023900854
-
The mitochondrial respiratory toxicity of cephalosporin antibiotics. An inhibitory effect on substrate uptake
-
Tune BM, Sibley RK and Hsu C-Y. The mitochondrial respiratory toxicity of cephalosporin antibiotics. An inhibitory effect on substrate uptake. J Pharmacol Exp Ther 245: 1054-1059, 1988.
-
(1988)
J Pharmacol Exp Ther
, vol.245
, pp. 1054-1059
-
-
Tune, B.M.1
Sibley, R.K.2
Hsu, C.-Y.3
-
13
-
-
0024440759
-
Thienamycin nephrotoxicity: Mitochondrial injury and oxidative effects of imipenem in the rabbit kidney
-
Tune BM, Fravert D and Hsu C-Y, Thienamycin nephrotoxicity: Mitochondrial injury and oxidative effects of imipenem in the rabbit kidney. Biochem Pharmacol 38: 3779-3783, 1989.
-
(1989)
Biochem Pharmacol
, vol.38
, pp. 3779-3783
-
-
Tune, B.M.1
Fravert, D.2
Hsu, C.-Y.3
-
14
-
-
0024598780
-
The oxidative and mitochondrial toxic effects of cephalosporin antibiotics in the kidney. A comparative study of cephaloridine and cephaloglycin
-
Tune BM, Fravert D and Hsu C-Y, The oxidative and mitochondrial toxic effects of cephalosporin antibiotics in the kidney. A comparative study of cephaloridine and cephaloglycin. Biochem Pharmacol 38: 795-802, 1989.
-
(1989)
Biochem Pharmacol
, vol.38
, pp. 795-802
-
-
Tune, B.M.1
Fravert, D.2
Hsu, C.-Y.3
-
15
-
-
0041524546
-
The renal tubular transport and nephrotoxicity of beta-lactam antibiotics
-
(Eds. Anders MW, Dekant W, Henschler D, Oberleithner H and Silbernagl S), Academic Press, Orlando, FL
-
Tune BM, The renal tubular transport and nephrotoxicity of beta-lactam antibiotics. In: Renal Disposition and Nephrotoxicity of Xenobiotics (Eds. Anders MW, Dekant W, Henschler D, Oberleithner H and Silbernagl S), pp. 249-267. Academic Press, Orlando, FL, 1993.
-
(1993)
Renal Disposition and Nephrotoxicity of Xenobiotics
, pp. 249-267
-
-
Tune, B.M.1
-
16
-
-
0024274131
-
Nephrotoxic potential of first-, second-, and third-generation cephalosporins
-
Cojocel C, Göttsche U, Tölle K-L and Baumann K, Nephrotoxic potential of first-, second-, and third-generation cephalosporins. Arch Toxicol 62: 458-464, 1988.
-
(1988)
Arch Toxicol
, vol.62
, pp. 458-464
-
-
Cojocel, C.1
Göttsche, U.2
Tölle, K.-L.3
Baumann, K.4
-
17
-
-
0025113468
-
Renal cell cultures: A tool for studying tubular function and nephrotoxicity
-
Gstraunthaler G, Steinmassl D and Pfaller W, Renal cell cultures: A tool for studying tubular function and nephrotoxicity. Toxicol Lett 53: 1-7, 1990.
-
(1990)
Toxicol Lett
, vol.53
, pp. 1-7
-
-
Gstraunthaler, G.1
Steinmassl, D.2
Pfaller, W.3
-
18
-
-
0019847157
-
Renal tolerance of ceftazidime in animals
-
Capel-Edwards K and Pratt DAH, Renal tolerance of ceftazidime in animals. J Antimicrob Chemother 8 (Suppl B): 241-245, 1981.
-
(1981)
J Antimicrob Chemother
, vol.8
, Issue.SUPPL. B
, pp. 241-245
-
-
Capel-Edwards, K.1
Pratt, D.A.H.2
-
19
-
-
0023551772
-
-
EORTC International Antimicrobial Therapy Cooperative Group, ceftazidime combined with a short or long course of amikacin for empirical therapy of Gram-negative bacteremia in cancer patients with granulocytopenia. N Engl J Med 317: 1692-1698, 1987.
-
(1987)
N Engl J Med
, vol.317
, pp. 1692-1698
-
-
-
20
-
-
0024341357
-
A comparison of double β-lactam combinations with netilmicin/ureidopenicillin regimens in the empirical therapy of febrile neutropenic patients
-
Kibbler CC, Prentice HG, Sage RJ, Hoffbrand AV, Brenner MK, Mannan P, Warner P, Bhamra A and Noone P, A comparison of double β-lactam combinations with netilmicin/ureidopenicillin regimens in the empirical therapy of febrile neutropenic patients. J Antimicrob Chemother 23: 759-771, 1989.
-
(1989)
J Antimicrob Chemother
, vol.23
, pp. 759-771
-
-
Kibbler, C.C.1
Prentice, H.G.2
Sage, R.J.3
Hoffbrand, A.V.4
Brenner, M.K.5
Mannan, P.6
Warner, P.7
Bhamra, A.8
Noone, P.9
-
21
-
-
0013904918
-
Acute toxicity of cephaloridine, an antibiotic derived from cephalosporin C
-
Atkinson RM, Currie JP, Dayis B, Pratt DAH, Sharpe HM and Tomich EG, Acute toxicity of cephaloridine, an antibiotic derived from cephalosporin C. Toxicol Appl Pharmacol 8: 398-406, 1966.
-
(1966)
Toxicol Appl Pharmacol
, vol.8
, pp. 398-406
-
-
Atkinson, R.M.1
Currie, J.P.2
Dayis, B.3
Pratt, D.A.H.4
Sharpe, H.M.5
Tomich, E.G.6
-
23
-
-
0018879755
-
Biliary excretion of cephalosporins in rats: Influence of molecular weight
-
Wright WE and Line VD, Biliary excretion of cephalosporins in rats: Influence of molecular weight. Antimicrob Agents Chemother 17: 842-846, 1980.
-
(1980)
Antimicrob Agents Chemother
, vol.17
, pp. 842-846
-
-
Wright, W.E.1
Line, V.D.2
-
24
-
-
0014817232
-
Nephrotoxicity due to cephaloridine: A light- and electron-microscopic study in rabbits
-
Silverblatt F, Turck M and Bulger R, Nephrotoxicity due to cephaloridine: A light- and electron-microscopic study in rabbits. J Infect Dis 122: 33-44, 1970.
-
(1970)
J Infect Dis
, vol.122
, pp. 33-44
-
-
Silverblatt, F.1
Turck, M.2
Bulger, R.3
-
25
-
-
0020181505
-
Pathogenesis of nephrotoxicity of cephalosporins and aminoglycosides: A review of current concepts
-
Silverblatt F, Pathogenesis of nephrotoxicity of cephalosporins and aminoglycosides: A review of current concepts. Rev Infect Dis 4: S360-S365, 1982.
-
(1982)
Rev Infect Dis
, vol.4
-
-
Silverblatt, F.1
-
26
-
-
0021798830
-
Carbapenems, a new class of beta-lactam antibiotics. Discovery and development of imipenem/cilastatin
-
Birnbaum J, Kahan FM, Kropp H and MacDonald JS, Carbapenems, a new class of beta-lactam antibiotics. Discovery and development of imipenem/cilastatin. Am J Med 78 (Suppl 6A): 3-21, 1985.
-
(1985)
Am J Med
, vol.78
, Issue.SUPPL. 6A
, pp. 3-21
-
-
Birnbaum, J.1
Kahan, F.M.2
Kropp, H.3
Macdonald, J.S.4
-
27
-
-
0027943664
-
Preventive effect of betamipron on nephrotoxicity and uptake of carbapenems in rabbit renal cortex
-
Hirouchi Y, Naganuma H, Kawahara Y, Okada R, Kamiya A, Inui K and Hori R, Preventive effect of betamipron on nephrotoxicity and uptake of carbapenems in rabbit renal cortex. Jpn J Pharmacol 66: 1-6, 1994.
-
(1994)
Jpn J Pharmacol
, vol.66
, pp. 1-6
-
-
Hirouchi, Y.1
Naganuma, H.2
Kawahara, Y.3
Okada, R.4
Kamiya, A.5
Inui, K.6
Hori, R.7
-
28
-
-
0014099154
-
Nephron transport and renal tubular effects of cephaloridine in animals
-
Child KJ and Dodds MG, Nephron transport and renal tubular effects of cephaloridine in animals. Br J Pharmacol Chemother 30: 354-370, 1967.
-
(1967)
Br J Pharmacol Chemother
, vol.30
, pp. 354-370
-
-
Child, K.J.1
Dodds, M.G.2
-
29
-
-
0016786623
-
Relationship between the transport and toxicity of cephalosporins in the kidney
-
Tune BM, Relationship between the transport and toxicity of cephalosporins in the kidney. J Infect Dis 132: 189-194, 1975.
-
(1975)
J Infect Dis
, vol.132
, pp. 189-194
-
-
Tune, B.M.1
-
30
-
-
0019131429
-
Mechanisms of cephalosporin nephrotoxicity. A comparison of cephaloridine and cephaloglycin
-
Tune BM and Fravert D, Mechanisms of cephalosporin nephrotoxicity. A comparison of cephaloridine and cephaloglycin. Kidney Int 18: 591-600, 1980.
-
(1980)
Kidney Int
, vol.18
, pp. 591-600
-
-
Tune, B.M.1
Fravert, D.2
-
31
-
-
0019301914
-
The effect of renal cation transport inhibitors on the in vivo and in vitro accumulation and efflux of cephaloridine
-
Wold JS and Turnipseed SA, The effect of renal cation transport inhibitors on the in vivo and in vitro accumulation and efflux of cephaloridine. Life Sci 27: 2559-2564, 1980.
-
(1980)
Life Sci
, vol.27
, pp. 2559-2564
-
-
Wold, J.S.1
Turnipseed, S.A.2
-
32
-
-
0020066448
-
Effects of ureteral obstruction on the toxicity of cephalosporins in the rabbit kidney
-
Wang PL, Prime DJ, Hsu C-Y and Tune BM, Effects of ureteral obstruction on the toxicity of cephalosporins in the rabbit kidney. J Infect Dis 145: 574-581, 1982.
-
(1982)
J Infect Dis
, vol.145
, pp. 574-581
-
-
Wang, P.L.1
Prime, D.J.2
Hsu, C.-Y.3
Tune, B.M.4
-
33
-
-
0013808622
-
Mechanism of action of penicillins: A proposal based on their structural similarity to acyl-D-alanyl-D-alanine
-
Tipper DJ and Strominger JL, Mechanism of action of penicillins: A proposal based on their structural similarity to acyl-D-alanyl-D-alanine. Proc Natl Acad Sci USA 54: 1133-1141, 1965.
-
(1965)
Proc Natl Acad Sci USA
, vol.54
, pp. 1133-1141
-
-
Tipper, D.J.1
Strominger, J.L.2
-
34
-
-
0020555408
-
The reactivity and binding of beta-lactam antibiotics in rabbit renal cortex
-
Browning MC and Tune BM, The reactivity and binding of beta-lactam antibiotics in rabbit renal cortex. J Pharmacol Exp Ther 226: 640-644, 1983.
-
(1983)
J Pharmacol Exp Ther
, vol.226
, pp. 640-644
-
-
Browning, M.C.1
Tune, B.M.2
-
36
-
-
0029129979
-
Effects of L-carnitine on the renal tubular transport of cephaloridine
-
Tune B, Effects of L-carnitine on the renal tubular transport of cephaloridine. Biochem Pharmacol 50: 562-564, 1995.
-
(1995)
Biochem Pharmacol
, vol.50
, pp. 562-564
-
-
Tune, B.1
-
37
-
-
0015332763
-
Effect of organic acid transport inhibitors on renal cortical uptake and proximal tubular toxicity of cephaloridine
-
Tune BM, Effect of organic acid transport inhibitors on renal cortical uptake and proximal tubular toxicity of cephaloridine. J Pharmacol Exp Ther 181: 250-256, 1972.
-
(1972)
J Pharmacol Exp Ther
, vol.181
, pp. 250-256
-
-
Tune, B.M.1
-
38
-
-
0017750291
-
Inhibition of transport and prevention of toxicity of cephaloridine in the kidney. Dose-responsiveness of the rabbit and the guinea pig to probenecid
-
Tune BM, Wu K-Y and Kempson RL, Inhibition of transport and prevention of toxicity of cephaloridine in the kidney. Dose-responsiveness of the rabbit and the guinea pig to probenecid. J Pharmacol Exp Ther 202: 466-471, 1977.
-
(1977)
J Pharmacol Exp Ther
, vol.202
, pp. 466-471
-
-
Tune, B.M.1
Wu, K.-Y.2
Kempson, R.L.3
-
39
-
-
0029074065
-
Effects of nephrotoxic beta-lactam antibiotics on the mitochondrial metabolism of monocarboxylic substrates
-
Tune B, Effects of nephrotoxic beta-lactam antibiotics on the mitochondrial metabolism of monocarboxylic substrates. J Pharmacol Exp Ther 274: 194-199, 1995.
-
(1995)
J Pharmacol Exp Ther
, vol.274
, pp. 194-199
-
-
Tune, B.1
-
41
-
-
0023854866
-
Comparative toxicities of cephalosporin antibiotics in a rabbit kidney cell line (LLC-RK1)
-
Williams PD, Laska DA, Tay LK and Hottendorf GH, Comparative toxicities of cephalosporin antibiotics in a rabbit kidney cell line (LLC-RK1). Antimicrob Agents Chemother 32: 314-318, 1988.
-
(1988)
Antimicrob Agents Chemother
, vol.32
, pp. 314-318
-
-
Williams, P.D.1
Laska, D.A.2
Tay, L.K.3
Hottendorf, G.H.4
|