Wild-type p53 induces diverse effects in 32D cells expressing different oncogenes

Molecular and Cellular Biology

Volumn 16, Issue 2, 1996, Pages 487-495

  Soddu, Silvia ^a   Blandino, Giovanni ^a,b   Scardigli, Raffaella ^a   Martinelli, Roberta ^a   Rizzo, Maria Giulia ^a   Crescenzi, Marco ^a   Sacchi, Ada ^a  

^a REGINA ELENA NATIONAL CANCER INSTITUTE   (Italy)

^b WEIZMANN INSTITUTE OF SCIENCE   (Israel)

Author keywords

[No Author keywords available]

Indexed keywords

INTERLEUKIN 3; PROTEIN P53;

ANIMAL CELL; APOPTOSIS; ARTICLE; BONE MARROW CELL; CELL DIFFERENTIATION; CELL GROWTH; CELL TRANSFORMATION; MOUSE; NONHUMAN; ONCOGENE; PRIORITY JOURNAL; PROTEIN EXPRESSION; STEM CELL;

ANIMALIA;

EID: 0030060411     PISSN: 02707306     EISSN: None     Source Type: Journal    
DOI: 10.1128/MCB.16.2.487     Document Type: Article

References (64)

1. Ahuia, H., M. Bar-Eli, S. H. Advani, S. Benchimol, and M. G. Cline. 1989. Alteration in the p53 gene and the clonal evolution of the blast crisis of chronic myclocytic leukemia. Proc. Natl. Acad. Sci. USA 86:6783-6787.
2. Anderson, S. M., P. M. Carroll, and F. D. Lee. 1990 Abrogation of IL-3 dependent growth requires a functional v-src gene product: evidence for an autocrine growth cycle. Oncogene 5:317-325.
3. Ausubel, F. M., R. Brent, R. E. Kingston, D. D. Moore, J. G. Seidman, J. A. Smith, and K. Struhl (ed.). 1990. Current protocols in molecular biology. Wiley Interscience, New York.
4. Baker, S. J., E. R. Fearon, J. M. Nigro, S. R. Hamilton, A. C. Preisinger, et al. 1989. Chromosome 17 deletions and p53 gene mutations in colorectal carcinomas. Science 244:217-221.
5. Baker, S. J., S. Markowitz, E. R. Fearon, J. K. V. Willson, and B. Vogelstein. 1990 Suppression of human colorectal carcinoma cell growth by wild-type p53. Science 249:912-915
6. Blandino, G., R. Scardigli, M. G. Rizzo, M. Crescenzi, S. Soddu, and A. Sacchi. 1995. Wild-type p53 modulates apoptosis of normal, IL-3 deprived, hematopotetic cells. Oncogene 10:731-737
7. Canman, C. E., T. M. Gilmer, S. B. Coutts, and M. B. Kastan. 1995 Growth factor modulation of p53-mediated growth arrest versus apoptosis. Genes Dev 9:600-611.
8. Chen, P., Y. Chen, R. Bookstein, and W. H. Lee. 1990. Genetic mechanisms of tumor suppression by the human p53 gene Science 250:1576-1580.
9. Cheng, J., J. K. Yee, J. Yeargin, T. Friedmann, and M. Haas. 1992. Suppression of acute lymphoblastic leukemia by the human wild-type p53 gene Cancer Res. 52:222-226.
10. Chomczynski, P., and N. Sacchi. 1987. Single step method of RNA isolation by acidic guanidinium thiocyanate phenol extraction. Anal. Biochem 162: 156-159.
11. Clarke, A. R., C. A. Purdie, D. J. Harrison, R. G. Morris, C. C. Bird, M. L. Hooper, and A. H. Wyllie. 1993. Thymocyte apoptosis induced by p53- dependent and independent pathways Nature (London) 362:849-852.
12. Courtneidge, S. A., R. Dhand, D. Pilat, G. M. Twamley, M. D. Waterfield, and M. F. Roussel. 1993 Activation of Src family kinases by colony stimulating factor-1, and their association with its receptor. EMBO J. 12:943-950.
13. Donehower, L. A., M. Harvey, B. L. Slagle, M. J. McArthur, C. A. Montgomery, Jr., J. S. Butel, and A. Bradley. 1992 Mice deficient for p53 are developmentally normal but susceptible to spontaneous tumors Nature (London) 356:215-221.
14. Dotto, G. P., L. F. Parada, and R. A. Weinberg. 1985. Specific growth response of ras-transformed embryo fibroblasts to tumor promoters. Nature (London) 318:472-475.
15. Dulik, V., W. K. Kaufmann, S. J. Wilson, T. D. Tisty, E. Lees, J. W. Harper, S. J. Elledge, and S. I. Reed. 1994. p53 dependent inhibition of cyclin- dependent kinase activities in human fibroblasts during radiation-induced G1 arrest. Cell 76:1013-1023.
16. Ehinger, M., E. Nilsson, A. M. Persson, I. Olson, and U. Gullberg. 1995 Involvement of the tumor suppressor gene p53 in tumor necrosis factor- induced differentiation of the leukemic cell line K562 Cell Growth Differ. 6:9-17.
17. El-Deiry, W. S., T. Tokino, V. E. Velculescu, D. B. Levy, R. Parsons, M. J. Trent, D. Lin, E. W. Mercer, K. W. Kinzler, and B. Vogelstein. 1993 WAF-1, a potential mediator of p53 tumor suppression Cell 75:817-825
18. Farmer, G., J. Bargonetti, H. Zhu, P. Friedman, R. Prywes, and C. Prives. 1992. Wild-type p53 activates transcription in vitro. Nature (London) 358: 83-86.
19. Fearon, E. R., and B. Vogelstein. 1990 A genetic model for colorectal tumorigenesis. Cell 61:759-767
20. Feinstein, E., R. P. Gale, J. Reed, and E. Canaani. 1992. Expression of the normal p53 gene induces differentiation of K562 cells Oncogene 7:1853-1857
21. Finlay, C. A., P. W. Hinds, and A. J. Levine. 1989. The p53 proto-oneogene can act a suppressor of transformation Cell 57:1083-1093
22. Gottlieb, E., R. Haffner, T. von Ruden, E. F. Wagner, and M. Oren. 1994. Down-regulation of wild-type p53 activity interferes with apoptosis of IL-3- dependent hematopoietic cells following IL-3 withdrawal EMBO J. 13: 1368-1374
23. Gottlieb, E., R. Haffner, E. Yonish-Rouach, T. von Ruden, E. F. Wagner, and M. Oren. 1994. Wild type p53 activity contributes to dependence on hematopoietic survival factors, p. 31-45. In E Mihich and R T. Schimke (ed.), Apoptosis. Plenum Press, New York.
24. Greenberger, J. S., R. J. Eckner, A. Sakakeeny, P. Marks, D. Reid, G. Nabel, A. Hapel, J. N. Ihle, and K. C. Humphries. 1983. Interleukin-3 dependent hematopoietic progenitor cell lines. Fed. Proc. 42:2762-2771.
25. Greenberger, J. S., M. A. Sakakeeny, R. K. Humphries, C. J. Eaves, and R. J. Eckner. 1983. Demonstration of permanent factor-dependent multipotential (erythroid/neutrophil/basophil) hematopoietic progenitor cell lines Proc. Natl. Acad Sci. USA 80:2931-2935
26. Halevy, O., B. G. Novitch, D. B. Spicer, S. X. Skapek, J. Rhee, G. J. Hannon, D. Beach, and A. B. Lassar. 1995. Correlation of terminal cell cycle arrest of skeletal muscle with induction of p21 by MyoD Science 279:1018-1021
27. Johnson, P., D. Gray, M. Mowat, and S. Benchimol. 1991 Expression of wild-type p53 is not compatible with continued growth of p53-negative tumor cells. Mol. Cell Biol. 11:1-11.
28. Kemp, C. J., L. A. Donehower, A. Bradley, and A. Balmain. 1993. Reduction of p53 gene dosage does not increase initiation or promotion but enhances malignant progression of chemically induced skin tumors. Cell 74:813-822.
29. Kern, S. E., K. W. Kinzler, A. Bruskin, D. Jarosz, P. Friedman, C. Prives, and B. Vogelstein. 1991. Identification of p53 as a sequence-specific DNA binding protein. Science 252:1708-1711.
30. Kruger, A., and S. M. Anderson. 1991. The v-src oncogene blocks the differentiation of a murine myeloid progenitor cell line and induces a tumorigenic phenotype. Oncogene 6:245-256.
31. Kuerbitz, S. J., B. S. Plunkett, W. V. Walsh, and M. B. Kastan. 1992 Wild-type p53 is a cell cycle checkpoint determinant following irradiation Proc. Natl. Acad. Sci. USA 89:7491-7495.
32. La Rocca, A., and F. Tatò, Unpublished data.
33. Lee, J. C., A. J. Hapel, and J. N. Ihle. 1982. Constitutive production of a unique lymphokine (IL-3) by the Wehi-3 cell line. J Immunol. 128:2393-2398.
34. Livingstone, L., A. White, J. Sprouse, E. Livanos, T. Jacks, and T. D. Tisty. 1992. Altered cell cycle arrest and gene amplification potential accompany loss of wild-type p53. Cell 70:923-935.
35. Lowe, S. W., H. E. Ruley, T. Jacks, and U. E. Housman. 1993. p53-dependent apoptosis modulates the cytotoxicity of anticancer agents. Cell 74:957-967.
36. Lowe, S. W., E. M. Schmitt, S. W. Smith, B. A. Osborne, and T. Jacks. 1993. p53 is required tor radiation-induced apoptosis m mouse thymocytes. Nature (London) 362:847-852.
37. Lu, X., and D. P. Lane. 1993. Differential induction of transcriptionally active p53 following UV or ionizing radiation: defects in chromosome instability syndromes? Cell 75:765-778.
38. Martinez, J., I. Georgoff, J. Martinez, and A. J. Levine. 1991 Cellular localization and cell cycle regulation by a temperature-sensitive p53 protein. Genes Dev. 5:151-159.
39. Mavilio, F., B. L. Kreider, M. Valtieri, G. Naso, N. Shirsat, D. Venturelli, E. P. Reddy, and G. Rovera. 1989. Alteration of growth and differentiation factors response by Kirsten and Harvey sarcoma viruses in the IL-3 dependent murine hematopoietic cell line 32D c13(G). Oncogene 4:301-308
40. Metcalf, D. 1989 The molecular control of cell division, differentiation commitment and maturation in hematopoietic cells. Nature (London) 339: 27-30.
41. Michalovitz, D., O. Halevy, and M. Oren. 1990. Conditional inhibition of transformation and of cell proliferation by a temperature-sensitive mutant of p53 Cell 62:671-680.
42. Migliaccio, G., A. R. Migliaccio, B. L. Kreider, G. Rovera, and J. W. Adamson. 1989 Selection of lineage-restricted cell lines immortalized at different stages of hematopoietic differentiation from the murine cell line 32D J Cell Biol. 109:833-841.
43. Morgenstern, J. P., and H. Land. 1990. Advanced mammalian gene transfer high titre retroviral vectors with multiple drug selection markets and a complementary helper-free packaging cell line. Nucleic Acids Res. 18:3587- 3596.
44. Ozturk, M., F. Ponchel, and A. Puisieux. 1992. p53 as a potential target in cancer therapy Bone Marrow Transplant. 9(Suppl. 1):164-170.
45. Patel, G., B. Kreider, G. Rovera, and E. P. Reddy. 1993. v-myb blocks granulacytc colony-stimulating factor-induced cell differentiation but not proliferation. Mol. Cell. Biol. 13:2269-2276.
46. Pierce, J. H., E. Di Marco, G. W. Cox, D. Lombardi, M. Ruggiero, L. Varesio, L. M. Wang, G. G. Choudhury, A. Y. Sakaguchi, and P. P. Di Fiore. 1990. Macrophage-colony-stimulating factor (CSF-1) induces proliferation, chemotaxis, and reversible monocytic differentiation in myeloid progenitor cells transfected with the human c-fms/CSF-1 receptor cDNA Proc. Natl Acad. Sci USA 87:5613-5617.
47. Rovera, G., M. Valtieri, F. Mavilio, and E. P. Reddy. 1987 Effect of Abelson murine leukemia virus on granulocytic differentiation and interleukin-3 dependence of a murine progenitor cell line. Oncogene 1:29-35.
48. Ryan, J. J., R. Danish, C. A. Gottlieb, and M. F. Clarke. 1993. Cell cycle analysis of p53-induced cell death in murine erythroleukemia cells. Mol. Cell Biol. 13:711-719.
49. Sachs, L. 1978. Control of normal cell differentiating and the phenotypic reversion of malignancy in myeloid leukemia. Nature (London) 274:535-539.
50. Sander, C. A., T. Yano, H. M. Clark, C. Harris, D. L. Longo, E. S. Jaffe, and M. Raffeld. 1993, p53 mutation is associated with progression in follicular lymphomas. Blood 82:1994-2004.
51. Sawyers, C. L., C. T. Denny, and O. N. Witte. 1991. Leukemia and the disruption of normal hematopoiesis Cell 64:337-350.
52. Sawyers, C. L., J. McLaughlin, A. Goga, M. Havlik, and O. Witte. 1994. The nuclear tyrosine kinase c-abl negatively regulates cell growth. Cell 77:121-131.
53. Shaulsky, G., N. Goldfinger, A. Peled, and V. Rotter. 1991. Involvement of wild-type p53 in pre-B-cell differentiation in vitro. Proc. Natl. Acad Sci. USA 88:8982-8986
54. Sidransky, D., T. Mikkelsen, K. Schwechheimer, M. L. Rosenblum, W. Cavanee, and B. Vogelstein. 1992. Clonal expression of p53 mutant cells is associated with brain tumor progression Nature (London) 355:846-847.
55. Soddu, S., and G. Blandino. Unpublished data.
56. Soddu, S., G. Blandino, G. Citro, R. Scardigli, G. Piaggio, A. Ferber, B. Calabretta, and A. Sacchi. 1994. Wild-type p53 gene expression induces granulocytic differentiation of HL-60 cells. Blood 83:2230-2237.
57. Steinman, R. A., B. Hoffman, A. Iro, C. Guillouf, D. A. Liebermann, and M. E. El-Houseini. 1994. Induction of p21 (WAF-1/CIP1) during differentiation. Oncogene 9:3389-3396.
58. Tanaka, N., M. Ishihara, M. Kitagawa, H. Karada, T. Kimura, T. Matsuyama, M. S. Lamphier, S. Aizawa, T. W. Mak, and T. Taniguchi. 1994. Cellular commitment to oncogene-induced transformation or apoptosis is dependent on the transcription factor IRF-1. Cell 77:829-839.
59. Taylor, S. J., and D. Shalloway. 1993. The cell cycle and c-src. Curr. Opin. Genet Dev 3:26-34.
60. Valtieri, M., D. J. Tweardy, D. Caracciolo, K. Johnson, F. Maviolo, S. Altmann, D. Santoli, and G. Rovera. 1987. Cytokine-dependent granulocytic differentiation. Regulation of proliferative and differentiative responses in a murine progenitor cell line. J. Immunol. 138:3829-3835.
61. Wang, J. Y. J. 1993. Abl tyrosine kinase in signal transduction and cell-cycle regulation, Curr. Opin. Genet Dev 3:35-43.
62. Williams, G. T., C. A. Smith, E. Spooncer, T. M. Dexter, and D. R. Taylor. 1990. Haematopoietic colony stimulating factors promote cell survival by suppressing apoptosis. Nature (London) 343:76-79
63. Yin, Y., M. A. Tainsky, Z. F. Bischoff, I. C. Strong, and G. M. Wahl. 1992. Wild-type p53 restores cell cycle control and inhibits gene amplification in cells with mutant p53 alleles. Cell 70:937-948.
64. Yonish-Rouach, E., D. Resnitzky, J. Lotem, L. Sachs, A. Kimchi, and M. Oren. 1991. Wild-type p53 induces apoptosis of myeloid leukaemic cells that is inhibited by interleukin-6 Nature (London) 352:345-347