Studies on the mechanism of toxicity of chlorophenols found in fish through quantitative structure-activity relationships

Water Research

Volumn 30, Issue 2, 1996, Pages 393-399

  Kishino, Takuo ^a   Kobayshi, Kunio ^b  

^a UBE NATIONAL COLLEGE OF TECHNOLOGY   (Japan)

^b KYUSHU UNIVERSITY   (Japan)

Author keywords

Chlorophenols; Fish; Mechanism of toxicity; QSAR

Indexed keywords

CHLORINE; CHLOROPHENOL; HYDROXYL GROUP;

ARTICLE; ATOM; CONTROLLED STUDY; DIFFUSION; DISSOCIATION; GOLDFISH; NONHUMAN; PRIORITY JOURNAL; QUANTITATIVE STRUCTURE ACTIVITY RELATION; TOXICITY;

CARASSIUS AURATUS;

EID: 0030059832     PISSN: 00431354     EISSN: None     Source Type: Journal    
DOI: 10.1016/0043-1354(95)00152-2     Document Type: Article

References (22)

1. Blackman G. E., Parke M. H. and Garton G. (1955) The physiological activity of substituted phenols. II. Relationships between physical properties and physiological activity. Arch. Biochem. Biophys. 54, 55-71.
2. Cohen E., Gamliel A. and Katan J. (1988) The fungitoxicity of chlorophenols to the pathogenic fungi, Fusarium oxysporum and Rhizoctonia solani: A structure-activity relationship study. Pestic. Sci. 24, 139-146.
3. Crandall C. A. and Goodnight C. J. (1959) The effect of various factors on the toxicity of sodium pentachlorophenate to fish. Limnol. Oceanogr. 4, 53-56.
4. Dalela R. C., Saroj Rani, Sarita Rani and Verma S. R. (1980) Influence of pH on the toxicity of phenol and its two derivatives pentacholorophenol and dinitrophenol to some fresh water teleosts. Acta Hydrochim. Hydrobiol. 8, 623-629.
5. Devillers J. and Chambon P. (1986) Acute toxicity and QSAR of chlorophenols on Daphnia magna. Bull. Environ. Contam. Toxicol. 37, 599-605.
6. Hansch C. and Dunn W. J. III (1972) Linear relationships between lipophilic character and biological activity of drugs. J. Pharm. Sci. 61, 1-19.
7. Holcombe G. W., Fiandt J. T. and Phipps G. L. (1980) Effects of pH increases and sodium chloride additions on the acute toxicity of 2,4-dichlorophenol to the fathead minnow. Wat. Res. 14, 1073-1077.
8. Huang Ju-Chang and Gloyna E. F. (1968) Effect of organic compounds on photosynthetic oxygenation - I. Chlorophyll destruction and suppression of photosynthetic oxygen production. Wat. Res. 2, 347-366.
9. Kishino T. (1989) Studies on the action mode of chlorophenols in fish. Doctoral thesis, Kyusyu University, Fukuoka, Japan.
10. Kishino T. and Kobayashi K. (1994) Relation between the chemical structures of chlorophenols and their dissociation constants and partition coefficients in several solvent-water systems. Wat. Res. 28, 1547-1552.
11. Kishino T. and Kobayashi K. (1996) Acute toxicity and structure activity relationships of chlorophenols in fish. Wat. Res. 30, 387-392.
12. Kishino T. and Kobayashi K. (1995b) Relation between toxicity and accumulation of chlorophenols at various pH. and their absorption mechanism in fish. Wat. Res. 29, 431-442.
13. Kobayashi K. and Akitake H. (1975) Studies on the metabolism of chlorophenols in fish - II. Turnover of absorbed PCP in goldfish. Nippon Suisan Gakkaishi 41, 93-99.
14. Kobayashi K., Kimura S. and Shimizu E. (1977) Studies on the metabolism of chlorophenols in fish - IX. Isolation and identification of pentachlorophenyl-β-glucuronide accumulated in bile of goldfish. Nippon Suisan Gakkaishi 43, 601-607.
15. Kobayashi K., Akitake H. and Manabe K. (1979) Studies on the metabolism of chlorophenols in fish - X. Relation between toxicity and accumulation of various chlorophenols in goldfish. Nippon Suisan Gakkaishi 45, 173-175.
16. Kobayashi K. and Kishino T. (1980) Studies on the metabolism of chlorophenols in fish - XIII. Effect of pH on the toxicity and accumulation of pentachlorophenol in goldfish. Nippon Suisan Gakkaishi 46, 167-170.
17. Liu D., Thomson K. and Kaiser K. L. E. (1982) Quantitative structure-toxicity relationship of halogenated phenols on bacteria. Bull. Environ. Contam. Toxicol. 29, 130-136.
18. McLeese D. W., Zitko V. and Peterson M. R. (1979) Structure-lethality relationships for phenols, anilines and other aromatic compounds in shrimp and clams. Chemosphere 8, 53-57.
19. Ribo J. M. and Kaiser K. L. E. (1983) Effects of selected chemicals to photoluminescent bacteria and their correlations with acute and sublethal effects on other organisms. Chemosphere 12, 1421-1442.
20. Rogers J. A. and Wong A. (1980) The temperature dependence and thermodynamics of partitioning of phenols in the n-octanol-water system. Int. J. Pharm. 6, 339-348.
21. Saarikoski J. and Viluksela M. (1981) Influence of pH on the toxicity of substituted phenols to fish. Arch. Environ. Contam. Toxicol. 10, 747-753.
22. Scherrer R. A. and Howard S. M. (1977) Use of distribution coefficients in quantitative structure-activity relationships. J. Med. Chem. 20, 53-58.