메뉴 건너뛰기




Volumn 31, Issue 3-4, 1996, Pages 113-121

NMR study of dideoxynucleotides with anti-human immunodeficiency virus (HIV) activity

Author keywords

2',3' Dideoxyribosyladenine 5' monophosphate; 2',3' Dideoxyribosylinosine 5' triphosphate; 3' Azido 2',3' dideoxyribosylthymine (AZT); 3' Azido 2',3' dideoxyribosylthymine 5' monophosphate; 3' Azido 2',3' dideoxyribosylthymine 5' triphosphate; Anti human immunodeficiency virus (HIV); NMR

Indexed keywords

2',3' DIDEOXYADENOSINE PHOSPHATE; 2',3' DIDEOXYINOSINE 5' TRIPHOSPHATE; DIDEOXYNUCLEOTIDE; UNCLASSIFIED DRUG; ZIDOVUDINE; ZIDOVUDINE 5' PHOSPHATE; ZIDOVUDINE 5' TRIPHOSPHATE;

EID: 0030059698     PISSN: 0165022X     EISSN: None     Source Type: Journal    
DOI: 10.1016/0165-022X(95)00027-O     Document Type: Article
Times cited : (3)

References (24)
  • 1
    • 0024317375 scopus 로고
    • New acquisition in the development of anti-HIV agents
    • De Clercq, E., New acquisition in the development of anti-HIV agents, Antiviral Res., 12 (1989) 1-20.
    • (1989) Antiviral Res. , vol.12 , pp. 1-20
    • De Clercq, E.1
  • 2
    • 0000137138 scopus 로고
    • Correlation between preferred sugar ring conformation and activity of nucleoside analogues against human immunodeficiency virus
    • Van Roey, P., Salenrno, J.M., Chu, C.K. and Schinazi, R.F., Correlation between preferred sugar ring conformation and activity of nucleoside analogues against human immunodeficiency virus, Proc. Natl. Acad. Sci. USA, 86 (1989) 3929-3933.
    • (1989) Proc. Natl. Acad. Sci. USA , vol.86 , pp. 3929-3933
    • Van Roey, P.1    Salenrno, J.M.2    Chu, C.K.3    Schinazi, R.F.4
  • 3
    • 0024437897 scopus 로고
    • NMR investigation on the structure and conformation of 3′-azido-2′,3′-dideoxyribosylthymine (AZT), an inhibitor of the HIV (AIDS virus)
    • Swapna, G.V.T., Jagannadh, B., Gurjar, M.K. and Kunwar, A.C., NMR investigation on the structure and conformation of 3′-azido-2′,3′-dideoxyribosylthymine (AZT), An inhibitor of the HIV (AIDS virus), Biochem. Biophys. Res. Commun., 164 (1989) 1086-1092.
    • (1989) Biochem. Biophys. Res. Commun. , vol.164 , pp. 1086-1092
    • Swapna, G.V.T.1    Jagannadh, B.2    Gurjar, M.K.3    Kunwar, A.C.4
  • 4
    • 0025925048 scopus 로고
    • 1H-NMR study of the sugar pucker of 2′,3′-dideoxynucleosides with anti-human immunodeficiency virus (HIV) activity
    • 1H-NMR study of the sugar pucker of 2′,3′-dideoxynucleosides with anti-human immunodeficiency virus (HIV) activity, Biochem. Biophys. Res. Commun., 179 (1991) 386-391.
    • (1991) Biochem. Biophys. Res. Commun. , vol.179 , pp. 386-391
    • Jagannadh, B.1    Reddy, D.V.2    Kunwar, A.C.3
  • 5
    • 0041019256 scopus 로고
    • NMR investigation on the structure and conformation of 2′,3′-dideoxynucleosides: Potent inhibitors of human immunodeficiency virus
    • Khetrapal, C.L. and Govil, G. (Eds.), Narosa Publishing House, New Delhi, India
    • Kunwar, A.C., Jagannadh, B. and Reddy, D.V., NMR investigation on the structure and conformation of 2′,3′-dideoxynucleosides: potent inhibitors of human immunodeficiency virus. In: Khetrapal, C.L. and Govil, G. (Eds.), Magnetic Resonance-Current Trends, Narosa Publishing House, New Delhi, India, 1991, pp. 171-186.
    • (1991) Magnetic Resonance-current Trends , pp. 171-186
    • Kunwar, A.C.1    Jagannadh, B.2    Reddy, D.V.3
  • 10
    • 2642628181 scopus 로고
    • A two-dimensional nuclear overhauser experiment with pure absorption phase in four quadrants
    • States, D.J., Haberkorn, R.A. and Ruben, D.J., A two-dimensional nuclear Overhauser experiment with pure absorption phase in four quadrants, J. Magn. Reson., 48 (1982) 286-292.
    • (1982) J. Magn. Reson. , vol.48 , pp. 286-292
    • States, D.J.1    Haberkorn, R.A.2    Ruben, D.J.3
  • 11
    • 0000246632 scopus 로고
    • Structure of toluence as determined by NMR of oriented molecules
    • Diehl, P., Kellerhals, H.P. and Niederberger, W., Structure of toluence as determined by NMR of oriented molecules, J. Magn. Reson., 4 (1971) 352-357.
    • (1971) J. Magn. Reson. , vol.4 , pp. 352-357
    • Diehl, P.1    Kellerhals, H.P.2    Niederberger, W.3
  • 13
    • 0015511563 scopus 로고
    • Conformational analysis of the sugar ring in nucleosides and nucleotides. A new description using the concept of pseudorotation
    • Altona, C. and Sundaralingam, M., Conformational analysis of the sugar ring in nucleosides and nucleotides. A new description using the concept of pseudorotation, J. Am. Chem. Soc., 94 (1972) 8205-8212.
    • (1972) J. Am. Chem. Soc. , vol.94 , pp. 8205-8212
    • Altona, C.1    Sundaralingam, M.2
  • 14
    • 20444483055 scopus 로고
    • The relationship between proton-proton NMR coupling constants and substituent electronegative I: An empirical generalization of the Karplus equation
    • Haasnoot, C.A.G., de Leeuw, F.A.A.M. and Altona, C., The relationship between proton-proton NMR coupling constants and substituent electronegative I: an empirical generalization of the Karplus equation, Tetrahedron, 36 (1980) 2783-2792.
    • (1980) Tetrahedron , vol.36 , pp. 2783-2792
    • Haasnoot, C.A.G.1    De Leeuw, F.A.A.M.2    Altona, C.3
  • 15
    • 84956382691 scopus 로고
    • The relationship between proton-proton NMR coupling constants and substituents electronegatives II-conformational analysis of the sugar ring in nucleosides and nucleotides in solution using a generalized Karplus equation
    • Haasnoot, C.A.G., de Leeuw, F.A.A.M., de Leeuw, H.P.M. and Altona, C., The relationship between proton-proton NMR coupling constants and substituents electronegatives II-conformational analysis of the sugar ring in nucleosides and nucleotides in solution using a generalized Karplus equation, Org. Magn. Reson., 15 (1981) 43-52.
    • (1981) Org. Magn. Reson. , vol.15 , pp. 43-52
    • Haasnoot, C.A.G.1    De Leeuw, F.A.A.M.2    De Leeuw, H.P.M.3    Altona, C.4
  • 16
    • 84912329691 scopus 로고
    • Nuclear magnetic resonance spectroscopy. Chemical shifts, coupling constants and molecular geometry
    • Sarma, R.H. (Ed.), Pergamon Press, New York, NY
    • Dhingra, M.M. and Sarma, R.H., Nuclear magnetic resonance spectroscopy. Chemical shifts, coupling constants and molecular geometry. In: Sarma, R.H. (Ed.), Stereodynamics of Molecular Systems, Pergamon Press, New York, NY, 1979, pp. 3-38.
    • (1979) Stereodynamics of Molecular Systems , pp. 3-38
    • Dhingra, M.M.1    Sarma, R.H.2
  • 17
    • 49349134796 scopus 로고
    • Conformations of nucleoosides and nucleotides
    • Emsley, J.W., Feeney, J., Shutcliffe, L.H. (Eds.), Pergamon Press, Oxford
    • Davies, D.B., Conformations of nucleoosides and nucleotides. In: Emsley, J.W., Feeney, J., Shutcliffe, L.H. (Eds.), Progress in NMR spectroscopy, Pergamon Press, Oxford, 12, 1978, pp. 135-225.
    • (1978) Progress in NMR Spectroscopy , vol.12 , pp. 135-225
    • Davies, D.B.1
  • 18
    • 0021436726 scopus 로고
    • 13NMR in conformational analysis of nucleic acid fragments 2. A reparametrization of the Karplus equation for vicinal NMR coupling constants in CCOP and HCOP fragments
    • 13NMR in conformational analysis of nucleic acid fragments 2. A reparametrization of the Karplus equation for vicinal NMR coupling constants in CCOP and HCOP fragments, J. Biomol. Struct. Dynamics, 1 (1984) 1387-1405.
    • (1984) J. Biomol. Struct. Dynamics , vol.1 , pp. 1387-1405
    • Lankhorst, P.P.1    Haasnoot, C.A.G.2    Erkelens, C.3    Altona, C.4
  • 21
    • 0342389680 scopus 로고
    • Application of molecular mechanics to the study of drug-membrane interactions: The role of molecular conformation in the passive membrane permiability of zidovudine (AZT)
    • Painter, G.R., Shockcor, J.P. and Andrews, C.W., Application of molecular mechanics to the study of drug-membrane interactions: the role of molecular conformation in the passive membrane permiability of zidovudine (AZT), Adv. Mol. Model., 2 (1990) 135-163.
    • (1990) Adv. Mol. Model. , vol.2 , pp. 135-163
    • Painter, G.R.1    Shockcor, J.P.2    Andrews, C.W.3
  • 22
    • 0027295759 scopus 로고
    • A comparison of the conformations of the 5′-triphosphates of zidovudine (AZT) and thymidine bound to HIV-reverse transcriptase
    • Painter, G.R., Aulabaugh, A.E. and Webster Andrews, C., A comparison of the conformations of the 5′-triphosphates of zidovudine (AZT) and thymidine bound to HIV-reverse transcriptase, Biochem. Biophys. Res. Commun., 191 (1993) 1166-1171.
    • (1993) Biochem. Biophys. Res. Commun. , vol.191 , pp. 1166-1171
    • Painter, G.R.1    Aulabaugh, A.E.2    Webster Andrews, C.3
  • 23
    • 0027971493 scopus 로고
    • Two-dimensional transferred nuclear overhauser effect spectroscopy (TRNOESY) studies of nucleotide conformation in arginene kinase complexes
    • Murali, N., Jarori, G.K. and Nageswara Rao, B.D., Two-dimensional transferred nuclear Overhauser effect spectroscopy (TRNOESY) studies of nucleotide conformation in arginene kinase complexes, Biochemistry, 33 (1994) 14227-14236.
    • (1994) Biochemistry , vol.33 , pp. 14227-14236
    • Murali, N.1    Jarori, G.K.2    Nageswara Rao, B.D.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.