Amrinone reverses bupivacaine-induced regional myocardial dysfunction

Acta Anaesthesiologica Scandinavica

Volumn 40, Issue 1, 1996, Pages 47-52

  Fujita, Y ^a  

^a KAWASAKI MEDICAL SCHOOL   (Japan)

Author keywords

Anesthetic, local: bupivacaine; Heart: myocardial contractility; Pharmacology: amrinone

Indexed keywords

AMRINONE; BUPIVACAINE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CARDIOTOXICITY; CARDIOVASCULAR EFFECT; CONTROLLED STUDY; DOG; DRUG EFFECT; HEART MUSCLE CONTRACTILITY; HEMODYNAMICS; INTRAVENOUS DRUG ADMINISTRATION; NONHUMAN; PRIORITY JOURNAL;

EID: 0030059528     PISSN: 00015172     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1399-6576.1996.tb04387.x     Document Type: Article

References (20)

1. Bernards CM, Carpenter RL, Kenter ME, Brown DL, Rupp SM, Thompson GE. Effects of epinephrine on central nervous system and cardiovascular system toxicity of bupivacaine in pigs. Anesthesiology 1989: 71: 711-717.
2. de La Coussaye JE, Eledjam J-J, Bassoul B, Bruelle P, Lefrant J-Y, Peray PA et al. Receptor mechanisms for clonidine reversal of bupivacaine-induced impairment of ventricular conduction in pentobarbital-anesthetized dogs. Anesth Analg 1994: 78: 624-637.
3. Bernards CM, Carpenter RL, Rupp SM, Brown DL, Morse BV, Morell RC et al. Effects of midazolam and diazepam premedication on central nervous system and cardiovascular toxicity of bupivacaine in pigs. Anesthesiology 1989: 70: 318-323.
4. Lindgren L, Randell T, Suzuki N, Kyttä J, Yli-Hankala A, Rosenberg PH. The effect of amrinone on recovery from severe bupivacaine intoxication in pigs. Anesthesiology 1992: 77: 309-315.
5. Fujita Y. Comparative direct effects of lidocaine and bupivacaine on regional myocardial function in dogs at non-cardiovascular toxic levels. Anesth Analg 1994: 78: 1158-1163.
6. Leone BJ, Lehot JJ, Runciman WB, Welding RN, Ramsay JG, Arvieux CC et al. Effects of lignocaine and bupivacaine on regional myocardial function and coronary blood flow in anaesthetized dogs. Br J Anaesth 1988: 60: 671-679.
7. Lowenstein E. Regional length and thickness measurements. Br J Anaesth 1988: 60: 58S-64S.
8. Ismail EF, Kim S-J, Salem MR, Crystal GJ. Direct effects of propofol on myocardial contractility in in situ canine hearts. Anesthesiology 1992: 77: 964-972.
9. Water DD, Luz PD, Wyatt HL, Swan HJC, Forrester JS. Early changes in regional and global left ventricular function induced by graded reduction in regional coronary perfusion. Am J Cardiol 1977: 39: 537-543.
10. Buffington CW. The magnitude and duration of direct myocardial depression following intracoronary local anesthetics: a comparison of lidocaine and bupivacaine. Anesthesiology 1989: 70: 280-287.
11. Toda N, Nakajima M, Nishimura K, Miyazaki M. Responses of isolated dog arteries to amrinone. Cardiovasc Res 1984: 18: 174-182.
12. Makela VHM, Kapur PA. Amrinone blunts cardiac depression caused by enflurane or isoflurane anesthesia in dogs. Anesth Analg 1987: 66: 215-221.
13. Alousi AA, Canter JM, Fort DJ. The beneficial effect of amrinone on acute drug-induced heart failure in the anaesthetized dog. Cardiovasc Res 1985: 19: 483-494.
14. Morgan JP. Abnormal intracellular modulation of calcium as a major cause of cardiac contractile dysfunction. N Engl J Med 1991: 325: 625-632.
15. Coyle DE, Sperekalis N. Bupivacaine and lidocaine blockade of calcium-mediated slow action potentials in guinea pig ventricular muscle. J Pharmacol Exp Ther 1987: 242: 1001-1005.
16. Lynch C. Depression of myocardial contractility in vitro by bupivacaine, etidocaine, and lidocaine. Anesth Analg 1986: 65: 551-559.
17. Butterworth JF IV, Brownlow RC, Leith JP Pielipp RC, Cole LR. Bupivacaine inhibits cyclic-3′,5′ adenosine monophosphate production. A possible contributing factor to cardiovascular toxicity. Anesthesiology 1993: 79: 88-95.
18. Edelson J, Lejemtel TH, Alousi AA, Biddlecome CE, Maskin CS, Sonnenblick EH. Relationship between amrinone plasma concentration and cardiac index. Clin Pharm Ther 1981: 29: 723-728.
19. Levy JA, Bailey JM. Amrinone: pharmacokinetics and pharmacodynamics. J Cardiothorac Anesth 1989: 3: 10S-14S.
20. Bailey JM, Levy JH, Roger G, Szlam F, Hug CC jr. Pharmacokinetics of amrinone during cardiac surgery. Anesthesiology 1991: 75: 961-968.