Influence of T lymphocytes and major histocompatibility complex class II genes on diabetes susceptibility in the NOD mouse

Current Topics in Microbiology and Immunology

Volumn 206, Issue , 1996, Pages 51-66

  Slattery, R M ^a   Miller, J F A P ^b  

^a Biology and Environment   (Australia)

^b ROYAL MELBOURNE HOSPITAL   (Australia)

Author keywords

[No Author keywords available]

Indexed keywords

CD4 ANTIGEN; CD8 ANTIGEN; IA ANTIGEN; MAJOR HISTOCOMPATIBILITY ANTIGEN CLASS 2;

ANIMAL MODEL; ANTIGEN PRESENTING CELL; DISEASE PREDISPOSITION; IMMUNOREGULATION; INSULIN DEPENDENT DIABETES MELLITUS; MAJOR HISTOCOMPATIBILITY COMPLEX; MOUSE; NONHUMAN; PRIORITY JOURNAL; REVIEW; T LYMPHOCYTE;

ANIMALIA; MUS MUSCULUS;

EID: 0030059391     PISSN: 0070217X     EISSN: None     Source Type: Book Series    
DOI: 10.1007/978-3-642-85208-4_4     Document Type: Review

References (64)

1. Acha-Orbea H, McDevitt HO (1987) The first external domain of the nonobese diabetic mouse class II I-A beta chain is unique. Proc Natl Acad Sci USA 84 2435-2439
2. Allison J, Malcolm L, Chosich N, Miller JFAP (1992) Inflammation but not autoimmunity occurs in transgenic mice expressing constitutive levels of interleukin-2 in islet B cells Eur J Immunol 22: 1115-1121
3. Atkinson MA, Maclaren NK (1988) Autoantibodies in nonobese diabetic mice immunoprecipitate 64, 000-Mr islet antigen Diabetes 37: 1587-1590 (published erratum appears in Diabetes (1989) 38(5) inside front cover)
4. Baxter AG, Adams MA, Mandel TE (1989) Comparison of high- and low-diabetes-incidence NOD mouse strains Diabetes 38: 1296-1300
5. Bendelac A, Boitard C, Bach JF, Camaud C (1989) Neonatal induction of allogeneic tolerance prevents T cell-mediated autoimmunity in NOD mice Eur J Immunol 19: 611-616
6. Bendelac A, Boitard C, Bedossa P, Bazin H, Bach JF, Camaud C (1988) Adoptive T cell transfer of autoimmune nonobese diabetic mouse diabetes does not require recruitment of host B lymphocytes J Immunol 141: 2625-2628
7. Bendelac A, Carnaud C, Boitard C, Bach JF (1987) Syngenic transfer of autoimmune diabetes from diabetic NOD mice to healthy neonates. Requirement for both L3T4+ and Lyt-2+ T cells. J Exp Med 166: 823-832
8. Böhme J, Schuhbaur B, Kanagawa O, Benoist C, Mathis D (1990) MHC-linked protection from diabetes dissociated from clonal deletion of T cells. Science 249: 293-295
9. Chandy KG, Charles AM, Kershnar A, Buckingham B, Waldeck N, Gupta S (1984) Autologous mixed lymphocyte reaction in man. XV. Cellular and molecular basis of deficient autologous mixed lymphocyte response in insulin-dependent diabetes mellitus J Clin Immunol 4: 424-428
10. Charlton B, Mandel TE (1988) Progression from insulitis to beta-cell destruction in NOD mouse requires L3T4+ T-lymphocytes. Diabetes 37 1108-1112
11. Charlton B, Mandel TE (1989) Recurrence of insulitis in the NOD mouse after early prolonged anti-CD4 monoclonal antibody treatment. Autoimmunity 4: 1-7
12. Charlton B, Bacelj A, Mandel TE (1988) Administration of silica particles or anti-Lyt2 antibody prevents beta-cell destruction in NOD mice given cyclophosphamide. Diabetes 37: 930-935
13. Charlton B, Bacelj A, Slattery RM, Mandel TE (1989) Cyclophosphamide-induced diabetes in NOD/WEHI mice. Evidence for suppression in spontaneous autoimmune diabetes mellitus. Diabetes 38: 441-447
14. Cooke A (1990) An overview on possible mechanisms of destruction of the insulin-producing beta cell. Curr Top Microbiol Immunol 164: 125-142
15. Deng H, Apple R, Clare-Salzler M, Trembleau S, Mathis D, Adorini L, Sercarz E (1993) Determinant capture as a possible mechanism of protection afforded by major histocompatibility complex class II molecules in autoimmune disease J Exp Med 178: 1675-1680
16. Gammon G, Sercarz E (1989) How some T cells escape tolerance induction. Nature 342: 183-185
17. Garchon HJ (1992) Non-MHC-linked genes in autoimmune diseases. Curr Opin Immunol 4: 716-722
18. Hanafusa T, Sugihara S, Fujino KH, Miyagawa J, Miyazaki A, Yoshioka T, Yamada K et al. (1988) Induction of insulitis by adoptive transfer with L3T4+Lyt2- T-lymphocytes in T-lymphocyte-depleted NOD mice. Diabetes 37: 204-208
19. Harada M, Makino S (1986) Suppression of overt diabetes in NOD mice by anti-thymocyte serum or anti-Thy 1, 2 antibody Jikken Dobustu 35: 501-504
20. Hutchings P, Rosen H, O'Reilly L, Simpson E, Gordon S, Cooke A (1990) Transfer of diabetes in mice prevented by blockade of adhesion-promoting receptor on macrophages. Nature 348: 639-642
21. Ikehara S, Ohtsuki H, Good RA, Asamoto H, Nakamura T, Sekita K, Muso E et al. (1985) Prevention of type I diabetes in nonobese diabetic mice by allogenic bone marrow transplantation. Proc Natl Acad Sci USA 82: 7743-7747
22. Ikehara S, Kawamura M, Takao F, Inaba M, Yasumizu R, Than S, Hisha H et al. (1990) Organ-specific and systemic autoimmune diseases originate from defects in hematopoietic stern cells. Proc Natl Acad Sci USA 87: 8341-8344
23. Katz J, Benoist C, Mathis D (1993) Major histocompatibility complex class I molecules are required for the development of insulitis in non-obese diabetic mice Eur J Immunol 23: 3358-3360
24. Kaufman DL, Clare-Salzler M, Tian J, Forsthuber T, Ting GS, Robinson P, Atkinson MA et al (1993) Spontaneous loss of T-cell tolerance to glutamic acid decarboxylase in munne insulin-dependent diabetes. Nature 366: 69-72
25. Kida K, Kaino Y, Miyagawa T, Gotoh Y, Matsuda H, Kono T (1985) Effect of cyclosporin on insulitis and islet cell surface antibody in non-obese diabetic mice. Congress of the international Diabetes Federation, Madrid
26. Koike T, Itoh Y, Ishii T, Ito I, Takabayashi K, Maruyama N, Tomioka H et al (1987) Preventive effect of monoclonal anti-L3T4 antibody on development of diabetes in NOD mice. Diabetes 36: 539-541
27. La Face DM, Peck AB (1989) Reciprocal allogeneic bone marrow transplantation between NOD mice and diabetes-nonsusceptible mice associated with transfer and prevention of autoimmune diabetes Diabetes 38 894-901
28. Lee KU, Amano K, Yoon JW (1988) Evidence for initial involvement of macrophage in development of insulitis in NOD mice Diabetes 37: 989-991
29. Lund T, O'Reilly L, Hutchings P, Kanagawa O, Simpson E, Gravely R, Chandler P et al. (1990) Prevention of insulin-dependent diabetes mellitus in non-obese diabetic mice by transgenes encoding modified I-A beta-chain or normal I-E alpha-chain. Nature 345: 727-729
30. Makino S, Harada M, Kishimoto Y, Hayashi Y (1986) Absence of insulitis and overt diabetes in athymic nude mice with NOD genetic background. Jikken Dobutsu 35: 495-498
31. Michel C, Boitard C, Bach JF (1989) Insulin autoantibodies in non-obese diabetic (NOD) mice. Clin Exp Immunol 75: 457-460
32. Miller BJ, Appel MC, O'Neil JJ, Wicker LS (1988) Both the Lyt-2+ and L3T4+ T cell subsets are required for the transfer of diabetes in nonobese diabetic mice J Immunol 140: 52-58
33. Miller JFAP, Flavell R (1994) T cell tolerance and autoimmunity in transgenic models of central and peripheral tolerance. Curr Opin Immunol 6 892-899
34. Miyazaki T, Uno M, Uehira M, Kikutani H, Kishimoto T, Kimoto M, Nishimoto H et al (1990) Direct evidence for the contribution of the unique I-ANOD to the development of insulitis in non-obese diabetic mice. Nature 345: 722-724
35. Mori Y, Suko M, Okudaira H, Matsuba I, Tsuruoka A, Sasaki A, Yokoyama H et al. (1986) Preventive effects of cyclosporin on diabetes in NOD mice. Diabetologia 29: 244-247
36. Nagata M, Yokono K, Hayakawa M, Kawase Y, Hatamori N, Ogawa W, Yonezawa K et al. (1989) Destruction of pancreatic islet cells by cytotoxic T lymphocytes in nonobese diabetic mice. J Immunol 143. 1155-1162
37. Nishimoto H, Kikutani H, Yamamura K, Kishimoto T (1987) Prevention of autoimmune insulitis by expression of I-E molecules in NOD mice. Nature 328: 432-434
38. Ogawa M, Maruyama T, Hasegawa T, Kanaya T, Kobayashi F, Tochino Y, Uda H (1985) The inhibitor effect of neonatal thymectomy on the incidence of insulitis in non-obese diabetic mice. Biomed Res 6: 103-106
39. Parish NM, Chandler P, Quartey-Papafio R, Simpson E, Cooke A (1993) The effect of bone marrow and thymus chimerism between non-obese diabetic (NOD) and NOD-E transgenic mice, on the expression and prevention of diabetes. Eur J Immunol 23: 2667-2675
40. Pennline KJ, Roque GE, Monahan M (1994) Recombinant human IL-10 prevents the onset of diabetes in the nonobese diabetic mouse Clin Immunol Immunopathol 71: 169-175
41. Ploegh H, Benaroch P (1993) MHC class II dimer of dimers. Nature 364: 16-17
42. Podolin PL, Pressey A, DeLarato NH, Fischer PA, Peterson LB, Wicker LS (1993) I-E+ nonobese diabetic mice develop insulitis and diabetes J Exp Med 178: 793-803
43. Pontessilli O, Carotenuto P, Gazda LS, Pratt PF, Prowse SJ (1987) Circulating lymphocyte populations and autoantibodies in non-obese diabetic (NOD) mice: a longitudinal study. Clin Exp Immunol 70. 84-93
44. Reddy S, Biddy N, Elliott RB (1990) Longitudinal study of islet cell antibodies and insulin autoantibodies and development of diabetes in non-obese diabetic (NOD) mice. Clin Exp Immunol 81: 400-405
45. Scott B, Liblau R, Degermann S, Marconi LA, Ogata L, Caton AJ, McDevitt HO et al. (1994) A role for non-MHC genetic polymorphism tn susceptibility to spontaneous autoimmunity Immunity 1: 73-82
46. Sempe P, Richard M-F, Bach J-F, Boitard C (1994) Evidence of CD4+ regulatory T cells in the non-obese diabetic male mouse. Diabetologia 37. 337-343
47. Serreze DV, Leiter EH (1991) Development of diabetogenic T cells from NOD/Lt marrow is blocked when an allo-H-2 haplotype is expressed on cells of hemopoietic origin, but not on thymic epithelium. J Immunol 147: 1222-1229
48. Serreze DV, Leiter EH, Christianson GJ, Greiner D, Roopenian DC (1994) Major histocompatibility complex class I-deficient NOD-B2mnull mice are diabetes and insulitis resistant Diabetes 43: 505-509
49. Serreze DV, Leiter EH, Worthen SM, Shultz LD (1988) NOD marrow stem cells adoptively transfer diabetes to resistant (NOD × NON)F1 mice Diabetes 37 252-255
50. Shizuru JA, Taylor EC, Banks BA, Gregory AK, Fathman CG (1988) Immunotherapy of the nonobese diabetic mouse: treatment with an antibody to T-helper lymphocytes. Science 240. 659-662
51. Singer SM, Tisch R, Yang XD, McDevitt HO (1993) An Abd transgene prevents diabetes in nonobese diabetic mice by inducing regulatory T cells. Proc Natl Acad Sci USA 9: 9566-9570
52. Slattery RM, Kjer NL, Allison J, Charlton B, Mandel TE, Miller JFAP (1990) Prevention of diabetes in non-obese diabetic I-Ak transgenic mice. Nature 345. 724-743
53. Slattery RM, Miller JFAP, Heath WR, Charlton B (1993) Failure of a protective major histocompatibility complex class II molecule to delete autoreactive T cells in autoimmune diabetes Proc Natl Acad Sci USA 90 10808-10810
54. Tisch R, Yang XD, Singer SM, Liblau RS, Fugger L, McDevitt HO (1993) Immune response to glutamic acid decarboxylase correlates with insulitis in non-obese diabetic mice. Nature 366: 72-75
55. Todd JA, Bell JI, McDevitt HO (1987) HLA-DQ beta gene contributes to susceptibility and resistance to insulin-dependent diabetes mellitus. Nature 329: 599-604
56. Uehirs M, Uno M, Kurner T, Kikutani H, Mori K, Inomoto T, Uede T et al. (1989) Development of autoimmune insulitis is prevented in E alpha d but not in A beta k NOD trasgenic mice. Int Immunol 1: 209-213
57. Uno M, Miyazaki T, Uehira M, Nishimoto H, Kimoto M, Miyazaki J, Yamamura K (1992) Complete prevention of diabetes in transgenic NOD mice expressing I-E molecules immunol Lett 31: 47-52
58. Wang Y, McDuffie M, Nomikos IN, Hao L, Lafferty KJ (1988) Effect of cyclosporine on immunologically mediated diabetes in nonobese diabetic mice. Transplantation 46 Suppl: 106S
59. Wang Y, Pontesilli O, Gill RG, La RF, Lafferty KJ (1991) The role of CD4+ and CD8+ T cells in the destruction of islet grafts by spontaneously diabetic mice. Proc Natl Acad Sci USA 88: 527-531
60. Wicker LS, Miller BJ, Chai A, Terada M, Mullen Y (1988) Expression of genetically determined diabetes and insulitis in the nonobese diabetic (NOD) mouse at the level of bone marrow-derived cells. Transfer of diabetes and insulitts to nondiabetic (NOD X B10) F1 mice with bone marrow cells from NOD mice J Exp Med 167: 1801-1810
61. Wicker LS, Leiter EH, Todd JA, Renjilian RJ, Peterson E, Fischer PA, Podolin PL et al. (1994) Beta 2-microglobulin-deficient NOD mice do not develop insulitis or diabetes. Diabetes 43. 500-504
62. Wogensen L, Lee MS, Sarvetnick N (1994) Production of interleukin 10 by islet cells accelerates immune-mediated destruction of beta cells in nonobese diabetic mice. J Exp Med 179: 1379-1384
63. Yasunami R, Bach JF (1988) Anti-suppressor effect of cyclophosphamide on the develop ment of spontaneous diabetes in NOD mice Eur J Immunol 18. 481-484
64. Ziegler AG, Vardi P, Ricker AT, Hattori M, Soeldner JS, Eisenbarth GS (1989) Radioassay determination of insulin autoantibodies in NOD mice. Correlation with increased risk of progression to overt diabetes Diabetes 38: 358-363