Decreased vascular reactivity of portal vein in rats with portal hypertension

Journal of Hepatology

Volumn 24, Issue 2, 1996, Pages 194-199

  Huang, Yi Tsau ^a   Lin, Han Chieh ^b   Yu, Pi Chin ^b   Lee, Fa Yauh ^b   Tsai, Yang Te ^b   Lee, Shou Dong ^b   Yang, May C M ^b  

^a NATIONAL YANG MING UNIVERSITY   (Taiwan)

^b TAIPEI VETERANS GENERAL HOSPITAL   (Taiwan)

Author keywords

Cyclic nucleotide; Intracellular calcium; Portal hypertension; Portal vein

Indexed keywords

2 [[2 (2,6 DIMETHOXYPHENOXY)ETHYL]AMINOMETHYL] 1,4 BENZODIOXAN; CALCIUM; CYCLIC AMP; CYCLIC GMP; NORADRENALIN; YOHIMBINE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BLOOD VESSEL REACTIVITY; CALCIUM CELL LEVEL; CONTROLLED STUDY; HUMAN; PATHOGENESIS; PORTAL HYPERTENSION; PORTAL VEIN; PRIORITY JOURNAL;

EID: 0030059181     PISSN: 01688278     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0168-8278(96)80029-8     Document Type: Article

References (45)

1. Vorobioff J, Bredfeldt JE, Groszmann RJ. Hyperdynamic circulation in portal hypertensive rat model: a primary factor for maintenance of chronic portal hypertension. Am J Physiol 1983; 244: G52-7.
2. Benoit JN, Granger DN. Splanchnic hemodynamic in chronic portal hypertension. Semin Liver Dis 1986; 6: 287-98.
3. Oberti F, Sogni P, Cailmail S, Moreau R, Pipy B, Lebrec D. Role of prostacyclin in hemodynamic alteration in conscious rats with extrahepatic or intrahepatic portal hypertension. Hepatology 1993; 18: 621-7.
4. Sitzmann JV, Bulkley GB, Mitchell MC, Campbell K. Role of prostacyclin in the splanchnic hyperemia contributing to portal hypertension. Ann Surg 1989; 209: 322-7.
5. Sherwin R, Joshi P, Hendler R, Felig P, Conn HO. Hyperglucagonemia in Laennec's cirrhosis. Role of portal-systemic shunting. N Engl J Med 1974; 290: 239-42.
6. Benoit JN, Barrowman JA, Harper SL, Kvietys PR, Granger DN. Role of humoral factors in the intestinal hyperemia associated with chronic portal hypertension. Am J Physiol 1984; 247: G486-93.
7. Claria J, Jimenez W, Ros J, Asbert M, Castro A, Arroyo V, Rivera F, Rodes J. Pathogenesis of arterial hypotension in cirrhotic rats with ascites: role of endogenous nitric oxide. Hepatology 1992; 15: 343-9.
8. Wnitro-L-arginine administration corrects peripheral vasodilation and systemic capillary hypotension and ameliorates plasma volume expansion and sodium retention in portal hypertensive rats. Hepatology 1993; 17: 84-90.
9. Braillon A, Gaudin C, Poo JL, Moreau R, Debaene B, Lebrec D. Plasma catecholamine concentrations are a reliable index of sympathetic vascular tone in patients with cirrhosis. Hepatology 1992; 15: 58-62.
10. Gaudin C, Braillon A, Poo JL, Kleber G, Moreau R, Lebrec D. Plasma catecholamines in patients with presinusoidal portal hypertension: comparison with cirrhotic patients and non-portal hypertensive subjects. Hepatology 1991; 13: 913-6.
11. Gaudin C, Ruget G, Braillon A, Selz F, Cuche JL, Lebrec D. Portal and arterial free and conjugated noradrenaline in two models of portal hypertension in rats. Life Sci 1989; 45: 1333-9.
12. Rodriquez-Puyol D, Alsasua A, Santos JC, Blanchart A, Novoa-Lopez JM. Plasma catecholamines and urinary excretion of their main metabolites in three models of portal hypertension. Clin Physiol Biochem 1988; 301-9.
13. Joh T, Granger DN, Benoit JN. Intestinal microvascular responsiveness to norepinephrine in chronic portal hypertension. Am J Physiol 1991; 260: H1135-43.
14. Pizcueta MP, Casamitjana R, Bosch R, Rodes J. Decreased systemic vascular sensitivity to norepinephrine in portal hypertensive rats: role of hyperglucagonism. Am J Physiol 1990; 258: G191-5.
15. Kiel JW, Pitts V, Benoit JN, Granger DN, Shephard AP. Reduced vascular sensitivity to norepinephrine in portal-hypertensive rats. Am J Physiol 1985; 248: G192-5.
16. Polio J, Sieber CC, Lerner E, Groszmann RJ. Cardiovascular hyporesponsiveness to norepinephrine, propranolol and nitroglycerin in portal-hypertensive and aged rats. Hepatology 1993; 18: 128-36.
17. Sitzmann JV, Li S-S, Wu Y-P, Groszmann RJ, Buckley GB. Decreased mesenteric vascular response to angiotensin II in portal hypertension. J Surg Res 1981; 61: 535-9.
18. Murray BM, Paller MS. Pressor resistance to vasopressin in sodium depletion, potassium depletion and cirrhosis. Am J Physiol 1986; 251: R525-30.
19. Cahill PA, Wu Y, Sitzmann JV. Altered adenylyl cyclase activities and G-protein abnormalities in portal hypertensive rabbits. J Clin Invest 1994; 93: 2691-700.
20. Huang YT, Lo JW, Lin HC, Tsai YT, Hong CY, Yang MCM. Change in vascular cAMP and cGMP contents in portal hypertensive rats. Pharmacology 1995; 50: 86-91.
21. Wu Z-Y, Benoit JN. Nonreceptor-mediated intestinal vasoconstriction in portal hypertensive rats. Am J Physiol 1994; 267: H370-5.
22. Hadengue A, Moreau R, Gaudin C, Bacq Y, Champigneulle B, Lebrec D. Total effective vascular compliance in patients with cirrhosis. A study of the response to acute blood volume expansion. Hepatology 1992; 15: 809-15.
23. Ingles AC, Hernandez I, Garcia-Estan J, Quesada T, Carbonell LF. Increased total vascular capacity in conscious cirrhotic rats. Gastroenterology 1992; 103: 275-81.
24. Chojkier M, Groszmann RJ. Measurement of portal systemic shunting in the rat by using T-labeled microspheres. Am J Physiol 1981; 140: G371-5.
25. 1-adrenoceptor of portal hypertensive rats. Br J Pharmacol 1994; 111: 439-44.
26. Chao TW, Yu PC, Kuo JS, Pang PKT, Yang MCM. Responsiveness to synthetic parathyroid hormone in the portal vein of portal hypertensive rats. J Hepatol 1992; 16: 326-31.
27. Abdelrahman A, Pang CCY. Differential venous effects of isoprenaline in conscious rats. Eur J Pharmacol 1990; 190: 321-7.
28. Murphy RA. Mechanics of vascular smooth muscle. In: Bohr DF, Somlyo AP, Sparks HV, eds. Handbook of Physiology, Section 2. The Cardiovascular System, Vol. II. Bethesda: American Physiology Society, 1980.
29. Yang MCM, Tu MS, Chou CK, Hong CY, Kuo JS. cAMP and vascular action of endothelin. Pharmacology 1991; 42: 252-6.
30. Wang R, Karpinski E, Pang PKT. Two types of calcium channels in isolated smooth muscle cells from the rat tail artery. Am J Physiol 1989; 256: H1361-8.
31. Ishikawa S, Saito T. Enhancement by veratridine and 60 mM KCl of vasopressin-induced 3′,3′-cyclic adenosine monophosphate production and cellular free calcium concentration in rat renal papillary collecting tubule cells in culture. Endocrinology 1989; 124: 265-71.
32. 2+ indicators with greatly improved fluorescence properties. J Biol Chem 1985; 260: 3440-50.
33. Bomzon A, Blendis LM. Vascular reactivity in experimental portal hypertension. Am J Physiol 1987; 252: G158-62.
34. Laffi G, Marra F, Failli P, Ruffiero M, Cecchi E, Carloni V, Giotti A, Gentilini P. Defective signal transduction in platelets from cirrhotics is associated with increased cyclic nucleotides. Gastroenterology 1993; 105: 148-56.
35. Farah AE. Glucagon and the circulation. Pharmacol Rev 1983; 35: 181-217.
36. Vane JR, Anggard EE, Botting RM. Regulatory functions of the vascular endothelium. N Engl J Med 1990; 323: 27-37.
37. Rodríguez-Pérez F, Isales CM, Groszmann RJ. Platelet cytosolic calcium, peripheral hemodynamics, and vasodilatory peptides in liver cirrhosis. Gastroenterology 1993; 105: 863-7.
38. 2+ localization and sensitivity in vascular smooth muscle. Trends Pharmacol Sci 1989; 10: 320-5.
39. Clapham DE. Calcium signaling. Cell 1995; 80: 259-68.
40. 1-like receptors linked to increases in intracellular calcium concentration and inhibition of cyclic AMP accumulation in cultured vascular smooth muscle cells derived from bovine basilar artery. J Pharmacol Exp Ther 1993; 266: 692-9.
41. 2+ is elevated in hypertrophic aortic muscle from hypertensive rats. Am J Physiol 1991; 260: H507-15.
42. i and force in ferret cardiac muscle after chemical loading of aequorin. Am J Physiol 1993; 265: C1703-10.
43. Castro A, Ros J, Jiménez W, Clària J, Llibre J, Leivas A, Arroyo V, Rivera F, Rodés J. Intracellular calcium concentration in vascular smooth muscle cells of rats with cirrhosis. J Hepatol 1994; 21: 521-6.
44. Hirata M, Kohse KP, Chang CH, Ikebe T, Murad F. Mechanism of cyclic GMP inhibition of inositol phosphate formation in rat aorta segments and cultured bovine aortic smooth muscle cells. J Biol Chem 1990; 265: 1268-73.
45. Kitten AM, Hymer TK, Katz MS. Bidirectional modulation of parathyroid hormone-responsive adenylyl cyclase by protein kinase C. Am J Physiol 1994; 266: E897-904.