Possible Involvement of Altered Na+-Ca2+ Exchange in Negative Inotropic Effects of Class I Antiarrhythmic Drugs on Rabbit and Rat Ventricles

Journal of Cardiovascular Pharmacology

Volumn 27, Issue 3, 1996, Pages 355-361

  Ito, Katsuaki ^a   Nagafuchi, Kazunori ^a   Taga, Atsuo ^a   Yorikane, Ryosuke ^b   Koike, Hiroyuki ^b  

^a UNIVERSITY OF MIYAZAKI   (Japan)

^b DAIICHI SANKYO CO   (Japan)

Author keywords

Flecainide; Lidocaine; Na+ Ca2+ exchange; RS 2135 Na+ channel; Sarcoplasmic reticulum

Indexed keywords

12 AMINO 2,3,3A,4,11,12,12A,12B OCTAHYDRO 10 HYDROXYISOQUINO[2,1,8 LMA]CARBAZOL 5(1H) ONE; ANTIARRHYTHMIC AGENT; CALCIUM ION; FLECAINIDE; LIDOCAINE; RYANODINE; SODIUM CHANNEL BLOCKING AGENT;

ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; COOLING; DOSE RESPONSE; HEART MUSCLE CONTRACTILE FORCE; HEART PAPILLARY MUSCLE; HEART VENTRICLE CONTRACTION; INOTROPISM; MALE; NONHUMAN; PRIORITY JOURNAL; RABBIT; RAT; SARCOPLASMIC RETICULUM; SODIUM CALCIUM EXCHANGE;

ANIMALS; ANTI-ARRHYTHMIA AGENTS; CALCIUM; CALCIUM CHANNELS; CARBAZOLES; DEPRESSION, CHEMICAL; DOSE-RESPONSE RELATIONSHIP, DRUG; FLECAINIDE; ISOQUINOLINES; LIDOCAINE; MALE; MYOCARDIAL CONTRACTION; RABBITS; RATS; RATS, WISTAR; RYANODINE; SODIUM; SODIUM CHANNELS;

EID: 0030058684     PISSN: 01602446     EISSN: None     Source Type: Journal    
DOI: 10.1097/00005344-199603000-00007     Document Type: Article

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