The neurofibromatosis type 1 (NF1) tumor suppressor gene and myeloid leukemia

Current Topics in Microbiology and Immunology

Volumn 211, Issue , 1996, Pages 232-239

  Largaespada, D A ^a   Brannan, C I ^b   Shaughnessy, J D ^a   Jenkins, N A ^a   Copeland, N G ^a  

^a NATIONAL CANCER INSTITUTE   (United States)

^b UNIVERSITY OF FLORIDA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

TRANSCRIPTION FACTOR;

CONFERENCE PAPER; LEUKEMOGENESIS; MOUSE; MUTATION; MYELOID LEUKEMIA; NEUROFIBROMATOSIS; NONHUMAN; PRIORITY JOURNAL; SIGNAL TRANSDUCTION; TUMOR SUPPRESSOR GENE;

ANIMALS; DISEASE MODELS, ANIMAL; FORECASTING; GENES, NEUROFIBROMATOSIS 1; GENES, RAS; HUMANS; LEUKEMIA, MYELOID; MICE;

EID: 0030058362     PISSN: 0070217X     EISSN: None     Source Type: Book Series    
DOI: 10.1007/978-3-642-85232-9_23     Document Type: Article

References (29)

1. Bader, J. L. (1986). "Neurofibromatosis and cancer." Ann. N. Y. Acad. Sci. 486: 56-65.
2. Bader, J. L. and R. W. Miller (1978). "Neurofibromatosis and childhood leukemia." J. Pediat. 92: 925-929.
3. Barbacid, M. (1990). "Ras oncogenes: their role in neoplasia." Eur. J. Clin. Invest. 20: 225-235.
4. Basu, T. N., D. H. Gutmann, J. A. Fletcher, T. W. Glover, F. S. Collins and J. Downward (1992). "Aberrant regulation of ras proteins in malignant tumor cells from type 1 neurofibromatosis patients." Nature 356: 713-715.
5. Bedigian, H. G., D. A. Johnson, N. A. Jenkins, N. G. Copeland and R. Evans (1984). "Spontaneous and induced leukemias of myeloid origin in recombinant inbred BXH-2 mice." J. Virol. 51: 586-594.
6. Boguski, M. S. and F. McCormick (1993). "Proteins regulating ras and its relatives." Nature 366: 643-653.
7. Bourne, H. R., D. A. Sanders and F. McCormick (1990). "The GTPase superfamily: a conserved switch for diverse cell functions." Nature 348: 125-132.
8. Brannan, C. I., A. S. Perkins, K. S. Vogel, N. Ratner, M. L. Nordlund, S. W. Reid, A. M. Buchberg, N. A. Jenkins, L. F. Parada and N. G. Copeland (1994). "Targeted disruption of the neurofibromatosis type -1 gene leads to developmental abnormalities in heart and various neural crest-derived tissues." Genes Devel. 8: 1019-1029.
9. Buchberg, A. M., H. G. Bedigian, N. A. Jenkins and N. G. Copeland (1990). "Evi-2, a common integration site involved in murine myeloid leukemogenesis." Mol. Cell. Biol. 10: 4658-4666.
10. Cawthon, R. M., L. B. Andersen, A. M. Buchberg, G. Xu, P. O'Connel, D. Viskochil, R. B. Weiss, M. R. Wallace, D. A. Marchuk, M. Culver, et al. (1991). "cDNA sequence and genomic structure of EVI-2B, a gene lying within an intron of the neurofibromatosis type 1 gene." Genomics 9: 446-460.
11. DeClue, J. E., A. G. Papageorge, J. A. Fletcher, S. R. Diehl, N. Ratner, W. C. Vass and D. R. Lowy (1992). "Abnormal regulation of mammalian p21ras contributes to malignant tumor growth in von Recklinghausen (Type 1) neurofibromatosis." Cell 69: 265-273.
12. Emanuel, P. D., L. J. Bates, R. B. Castleberry, R. J. Gualtieri and K. S. Zuckerman (1991). "Selective hypersensitivity to granulocyte-macrophage colony-stimulating factor by juvenile chronic myeloid leukemia hematopoietic progenitors." Blood 77: 925-929.
13. Golub, T. R., G. F. Barker, M. Lovett and D. G. Gilliland (1994). "Fusion of PDGF receptor β to a novel ets-like gene, tel, in chronic myelomonocytic leukemia with t(5;12) chromosomal translocation." Cell 77: 307-316.
14. Gutmann, D. H. and F. S. Collins (1993). "The neurofibromatosis type 1 gene and its protein product, neurofibromin." Neuron 10: 335-343.
15. Hope, D. G. and J. J. Mulvihill (1981). "Malignancy in neurofibromatosis." Adv. Neurol. 29: 33-56.
16. Jacks, T., T. S. Shih, E. M. Schmitt, R. T. Bronson, A. Bernards and R. A. Weinberg (1994). "Tumor predisposition in mice heterozygous for a targeted mutation in Nf1." Nature Genet. 7: 353-361.
17. Jacobs, A. (1992). "Gene mutations in myelodysplasia." Leuk. Res. 16: 47-50.
18. Janssen, J. W. G., A. C. M. Steenvoorden, J. Lyons, B. Anger, J. U. Bohlke, J. L. Bos, H. Seliger and C. R. Bartram (1987). "RAS gene mutations in acute and chronic myelocytic leukemias, chronic myeloproliferative disorders, and myelodysplastic syndromes." PNAS 84: 9228-9232.
19. Jenkins, N. A., N. G. Copeland, B. A. Taylor, H. G. Bedigian and B. K. Lee (1982). "Ecotropic murine leukemia virus DNA content of normal and lymphomatous tissues of BXH-2 recombinant inbred mice." J. Virol. 42: 379-388.
20. Kalra, R., D. C. Paderanga, K. Olson and K. M. Shannon (1994). "Genetic analysis is consistent with the hypothesis that NF1 limits myeloid growth through p21ras." Blood 84: 3435-3439.
21. Largaespada, D. A., J. D. Shaughnessy, N. A. Jenkins and N. G. Copeland (1995). "Retroviral insertion at the Evi-2 locus in BXH-2 myeloid leukemia cell lines disrupts Nf1 expression without changes in steady state ras-GTP levels." J. Virol. 69: 5095-5102.
22. Lubbert, M., J. M. Jr., G. Kitchingman, F. McCormick, R. Mertelsmann, F. Herrmann and H. P. Koeffler (1992). "Prevalence of N-ras mutations in children with myelodysplastic syndromes and acute myeloid leukemia." Oncogene 7: 263-268.
23. Neubauer, A., K. Shannon and E. Liu (1991). "Mutation of the ras protooncogenes in childhood monosomy 7." Blood 77: 594-598.
24. Padua, R. A., G. Carter, D. Hughes, J. Gow, C. Farr, D. Oscier, F. McCormick and A. Jacobs (1988). "RAS mutations in myelodysplasia detected by amplification, oligonucleotide hybridization, and transformation." Leukemia 2: 503-510.
25. Pendergast, A. M., L. A. Quilliam, L. D. Cripe, C. H. Bassing, Z. Dai, N. Li, A. Batzer, K. M. Rabun, C. J. Der, J. Schlessinger, et al. (1993). "BCR-ABL-induced oncogenesis is mediated by direct interaction of the SH2 domain of the GRB-2 adaptor protein." Cell 75: 175-185.
26. Puil, L., J. Lui, G. Gish, G. Mbamalu, D. Bowtell, P. G. Pelicci, R. Arlinghaus and T. Pawson (1994). "Bcr-abl oncoproteins bind directly to activators of the ras signalling pathway." EMBO J. 13: 764-773.
27. Sawyers, C. and C. T. Denny (1994). "Chronic myelomonocytic leukemia: Tel-a-kinase what ets all about." Cell 77: 171-173.
28. Shannon, K. M., P. O'Connell, G. A. Martin, D. Paderanga, K. Olson, P. Dinndorf and F. McCormick (1994). "Loss of thenormal NF1 allele from the bone marrow of children with type 1 neurofibromatosis and malignant myeloid disorders." New Eng. J. Med. 330: 597-601.
29. von Lohuizen, M. and A. Berns (1990). "Tumorigenesis by slow transforming retroviruses - an update." Biochim. Biophys. Acta. 1032 (2-3): 213-235.