Protective effects of tirilazad mesylate and metabolite U-89678 against blood-brain barrier damage after subarachnoid hemorrhage and lipid peroxidative neuronal injury

Journal of Neurosurgery

Volumn 84, Issue 2, 1996, Pages 229-233

  Smith, Sarah L ^a   Scherch, Heidi M ^a   Hall, Edward D ^a  

^a PFIZER INC   (United States)

Author keywords

21 aminosteroid; blood brain barrier; lipid peroxidation; neuron; subarachnoid hemorrhage; tirilazad; U 89678

Indexed keywords

21 [4 [2,6 BIS(1 PYRROLIDINYL) 4 PYRIMIDINYL] 1 PIPERAZINYL] 16ALPHA METHYLPREGNA 1,9(11) DIENE 3,20 DIONE; TIRILAZAD; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BLOOD BRAIN BARRIER; BRAIN INJURY; BRAIN ISCHEMIA; BRAIN PROTECTION; CELL SURVIVAL; CELL VIABILITY; CONTROLLED STUDY; DRUG EFFECT; DRUG POTENCY; LIPID PEROXIDATION; NERVE INJURY; NONHUMAN; PRIORITY JOURNAL; RAT; SPINAL CORD NERVE CELL; SUBARACHNOID HEMORRHAGE;

EID: 0030058338     PISSN: 00223085     EISSN: None     Source Type: Journal    
DOI: 10.3171/jns.1996.84.2.0229     Document Type: Article

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