The cross-reactivity of autoantibodies in connective tissue diseases

Clinical and Experimental Rheumatology

Volumn 14, Issue 4, 1996, Pages 425-431

  Caponi, L ^a  

^a UNIVERSITY OF PISA   (Italy)

Author keywords

autoantibodies; cross reactivity; lupus

Indexed keywords

AUTOANTIBODY;

ANALYTIC METHOD; ANTIBODY SPECIFICITY; ANTIGEN ANTIBODY REACTION; ANTIGEN SPECIFICITY; AUTOIMMUNITY; BINDING AFFINITY; CONNECTIVE TISSUE DISEASE; CROSS REACTION; HUMAN; MOLECULAR RECOGNITION; PATHOGENESIS; PRIORITY JOURNAL; REVIEW;

ANIMALS; AUTOANTIBODIES; AUTOANTIGENS; CONNECTIVE TISSUE DISEASES; CROSS REACTIONS; HUMANS;

EID: 0030057880     PISSN: 0392856X     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Review

References (63)

1. SHOENFELD Y: Idiotypic induction of autoimmunity: a new aspect of the idiotypic network, FASEB J 1994, 8, 1296-1301.
2. RUF J, FERRAND M, DURAND-GORDE JM, DE MICCO C, CARAYON P: Significance of thyroglobulin antibodies cross-reactive with thyroperoxidase (TGPO antibodies) in individual patients and immunized mice. Clin Exp Immunol 1993; 92: 65-72.
3. MAPPOURAS DG, PHILIPPOU G, HARALAMBOUS S, TZARTOS SJ, BALAFAS A, SOUVATZOGLOU A, LYMBERI P: Antibodies to acetylcolinesterase cross-reacting with thyroglobulin in myastenia gravis and Graves' disease. Clin Exp Immunol 1995; 100: 336-43.
4. VAN DE WATER J, TURCHANY J, LEUNG PSC, LAKE J, MUNOZ S, SURH CD, COPPEL R, ANSARI AFTA B, NAKANUMA Y, GERSHWIN ME: Molecular mimicry in primary biliary cirrhosis. J Clin Invest 1993; 91: 2653-64.
5. LONROT M, HYOTY H, KNIP M et al.: Antibody cross reactivity induced by the homologous regions in glutamic acid decarboxylase (GAD(65)) and 2C protein of coxackie virus B4. Clin Exp Immunol 1996; 104: 398-405.
6. ANDRE-SCHWARTZ J, DATTA SK, SHOENFELD Y, ISENBERG DA, STOLLAR D, SCHWARTZ RS: Binding of cytoskeletal proteins by monoclonal anti-DNA lupus autoantibodies. Clin Immunol Immunopathol 1984; 31: 261-71.
7. FAABER P, CAPEL PJA, RIJIKE TPM, VIERWINDEN G, VAN DE PUTTE LBA, KOENE RAP: Cross-reactivity of anti-DNA antibodies with proteoglycans. Clin Exp Immunol 1984; 55: 502-8.
8. FAABER P, RIJIKE TPM, VAN DE PUTTE LBA, CAPEL PJA, BERDEN JHM: Cross-reactivity of human and murine anti-DNA antibodies with heparan sulphate. The major glycosaminoglycan in glomerular basement membrane. J Clin Invest 1986; 77: 1824-30.
9. SHOENFELD Y, RAUCH J, MASSICOTTE M, DATTA SK, ANDRE-SCHWARTZ J, STOLLAR D, SCHWARTZ RS: Polyspecificity of monoclonal lupus autoantibodies produced by human-human hybridomas. N Engl J Med 1983; 308: 414-20.
10. LAFER EM, RAUCH J, ANDRZEJEWSKI C, MUDD D, FURIE B, SCHWARTZ RS, STOLLAR BD: Polyspecific monoclonal lupus autoantibodies reactive with both polynucleotides and phospholipids. J Exp Med 1981; 153: 897-909.
11. REICHLIN M, MARTIN A, TAYLOR-ALBER E, TSUKAZA K, ZHANG W, WOLFSON REICHLIN M, KOREN E, EBLING FM, TSAO B, HAHN BH: Lupus autoantibodies to native DNA cross-react with the A and D SnRNP polypeptides. J Clin Invest 1994; 93: 443-9.
12. SUN KH, LIU WT, TANG SJ, TSAI CY, HSIEH SC, WU TH, HAN SH: The expression of acidic ribosomal phosphoproteins on the surface membrane of different tissues in autoimmune and normal mice which are the target molecules for anti-double-stranded DNA antbodies. Immunology 1996; 87: 362-71.
13. PISETSKY DS, HOCH SO, KLATT CL, O'DONNELL MA, KEENE JD: Specificity and idiotypic analysis of a monoclonal anti-Sm antibody with anti-DNA activity. J Immunol 1985; 135: 4080-5.
14. BLOOM DD, DAVIGNON J-L, COHEN PL, EISENBERG RA, CLARKE SH: Overlap of the anti-Sm and anti-DNA responses of MRL/Mp-lpr/lpr mice. J Immunol 1993; 160: 1579-90.
15. ELKON KB, BONFA E, LLOVET R, EISENBERG RA: Association between anti-Sm and anti-ribosomal P protein autoantibodies in human systemic lupus erythematosus and MRL/lpr mice. J Immunol 1989; 143: 1549-54.
16. NOJIMA Y, MINOTA S, YAMADA A, TAKAKU F: Identification of an acidic ribosomal protein reactive with anti-Sm autoantibodies. J Immunol 1989; 143: 1915-20.
17. DE KEISER F, HOCH SO, TAKEI M, DANG H, DE KEYSER H, ROKEACH LA, TALAL N: Cross-reactivity of the B/B' sub-unit of the Sm ribonucleoprotein autoantigen with proline-rich polypeptides. Clin Immunol Immunopathol 1992; 62, 285-90.
18. LERNER EA, LERNER MR, JANEWAY J, STEITS A: Monoclonal antibodies to nucleic acid-containing cellular constituents: probes for molecular biology and autoimmune disease. Proc Natl Acad Sci USA 1981; 78: 2737-41.
19. REUTER R, ROTHE S, HABETS W, VAN VENROOIJ WJ, LUHRMANN R: Autoantibody production against the U small nuclear ribonuclear particle E, F and G in patients with connective tissue diseases. Eur J Immunol 1990; 20: 437-40.
20. HABETS WJ, HOET M, BRINGMANN P, LÜHRMANN R, VAN VENROOIJ W: Autoantibodies to ribonucleoprotein particles containing U2 small nuclear RNA. Embo J 1985; 4: 1545-50.
21. HABETS WJ, HOET MH, DE JONG BAW, VAN DER KEMP A, VAN VENROOIJ WJ: Mapping of B cell epitopes on small nuclear ribonuclear ribonucleoproteins that react with human autoantibodies as well as with experimentally-induced mouse monoclonal antibodies. J Immunol 1989; 143: 2560-6.
22. HABETS WJ, SILLEKENS PTG, HOET MH, MCALLISTER G, LERNER MR, VAN VENROOIJ WJ: Small nuclear RNA-associated proteins are immunologically related as revealed by mapping of autoimmune reactive-B cell epitopes. Proc Natl Acad Sci USA 1989; 86: 4674-8.
23. ROKEACH L, JANNATIPOUR M, HOCH S: Heterologous expression and epitope mapping of a human small nuclear ribonucleoprotein-associated Sm-B'/B autoantigen. J Immunol 1990; 144: 1015-22.
24. OHOSONE Y, MIMORIT, FUJII T, AKIZUKI M, MATSUOKA Y, IRIMAJIRI S, HARDIN JA, CRAFT J, HOMMA M: Autoantigenic epitopes of the B polypeptide of Sm small nuclear RNP particles. Arthritis Rheum 1992; 35: 960-6.
25. HABETS W, BERDEN JHM, HOCH SO, VAN VENROOIJ W: Further characterization and subcellular localization of Sm and U1 ribonucleoprotein antigens. Eur J Immunol 1985; 15: 992-7.
26. HIRAKATA M, CRAFT J, HARDIN JA: Autoantigenic epitopes of the B and D polypeptides of the U1 snRNP. J Immunol 1993; 150: 3592-601.
27. COUTINHO A, KAZATCHKINE MD, AVRAMEAS S: Natural autoantibodies. Curr Op Immunology 1995; 7: 812-8.
28. HUREZ V, DIETRIC G, KAVERY SV, KAZATCHKINE MD: Polyreactivity is a property of natural and disease-associated human autoantibodies. Scand J Immunol 1993; 38: 190-6.
29. BERNEMAND A, TERNYNCK T, AVRAMEAS S: Natural mouse IgG reacts with self antigens including molecules involved in the immune response. Eur J Immunol 1992; 22: 625-33.
30. KLINMAN DM: Cross-reactivity of IgM-secreting B cells from normal BALB/c mice. J Immunol 1992; 149: 3569-73.
31. GILBERT D, FREDERIC B, JOVELIN F, TRON F: Do naturally occurring autoantibodies participate in the constitution of the pathological B-cell repertoire in systemic lupus erythematosus? J Autoimmunity 1996; 9: 247-57.
32. BENJAMIN DC, BERZOFSKY JA, EAST IJ, GURD FRN, HANNUM C, LEACH SJ, MARGOLIASH E, MICHAEL JG, MILLER A, PRAGER EM, REICHLIN M, SERCARZ EE, SMITH-JILL SJ, TODD PE, WILSON AC: The antigenic structure of proteins: a reappraisal. Annu Rev Immunol 1984; 2: 67-101.
33. QUERY CC, KEENE JD: A human autoimmune protein associated with U1 RNA contains a region of homology that is cross reactive with retroviral p30gag antigen. Cell 1987; 51: 211-20.
34. ATKINSON MA, BOWMAN MA, CANPBELL L, DARROW BL, KAUFMAN DL, MACLAREN NK: Cellular immunity to a determinant common to glutamate decarboxylase and Coxsackie virus in insulin-dependent diabetes. J Clin Invest 1994; 94: 2125-9.
35. SABBATINI A, BOMBARDIERI S, MIGLIORINI P: Autoantibodies from patients with systemic lupus erythematosus bind a shared sequence of SmD and Epstein-Barr virus-encoded nuclear antigen EBNA-I. Eur J Immunol 1993; 23: 1146-52.
36. THEOFILOPOULOS AN: The basis of autoimmunity. Part I. Mechanisms of aberrant self recognition. Immunol Today 1995; 16: 90-8.
37. RADIC MZ, WEIGERT M: Genetic and structural evidence for antigen selection of anti-DNA antibodies. Annu Rev Immunol 1994; 12: 487-520.
38. BERZOFSKY JA: Intrinsic and extrinsic factors in protein antigenic structure. Science 1985; 229: 932-40.
39. BRENDEL V, DOHLMAN J, BLAISDELL BE, KARLIN S: Very long charge runs in systemic lupus erythematosus-associated autoantigens. Proc Natl Acad Sci USA 1991; 88: 1536-40.
40. BRONZE-DA-ROCHA E, MACHADO C, STAINES NA, SUNKEL CE: Systemic lupus erythematosus murine monoclonal DNA-binding antibodies recognize cytoplasmic and nuclear phosphorylated antigens that display cell cycle redistribution in HEp-2 cells. Immunology 1992; 77: 582-91.
41. BRADEN BC, POLJAK RJ: Structural features of the reactions between antibodies and protein antigens. FASEB J 1995; 9: 9-16.
42. RICHARDS FF, KONIGSBERG WH, ROSENSTEIN RW, VARGA JM: On the specificity of antibodies. Science 1975; 187: 130-7.
43. RADIC MZ, MACKLE J, ERICKSON J, MOL C, ANDERSON WF, WEIGERT M: Residues that mediate DNA binding of autoimmun antibodies. J Immunol 1993; 150: 4966-77.
44. ZOUALI M, MIGLIORINI P, STOLLAR DB: Murine lupus anti-DNA antibodies cross-react with the hapten (4-hydroxy-5-iodo-3-nitrophenyl) acetyl, but immunization-induced anti-DNA antibodies do not. Eur J Immunol 1987, 17: 509-13.
45. SHLOMCHIK M, MASCELLI M, SHAN H, RADIC MZ, PISETSKY D, MARSHAK-ROTHSTEIN A, WEIGERT M: Anti-DNA antibodies from autoimmune mice arise by clonal expansion and somatic mutation. J Exp Med 1990; 171: 265-97.
46. SHORES EW, EISENBERG RA, COHEN PL: Role of the Sm antigen in the generation of anti-Sm autoantibodies in the SLE prone MRL mouse. J Immunol 1986; 136: 3662-7.
47. SHLOMCHIK M, MARSHAK-ROTHSTEIN A, WOLFOWICZ CB, ROTHSTEIN TL, WEIGERT MG: The role of clonal selection and somatic mutation in autoimmunity. Nature 1987; 328: 805-11.
48. HABETS W, HOET MH, VAN VENROOIJ WJ: Epitope patterns of anti-RNP antibodies in rheumatic diseases. Evidence for an antigen-driven reesponse. Arthritis Rheum 1990; 33: 834-41.
49. TILLMAN DM, JOU NT, HILL RJ, MARION TN: Both IgM and IgG anti-DNA antibodies are the products of clonally selective B cell stimulation in (NZB x NZW) F1 mice. J Exp Med 1992; 176: 761-79.
50. SHAN H, SHLOMCHIK M, MARSHAK-ROTHSTEIN A, PISETSKY D, LITWIN S, WEIGERT MG: The mechanism of autoantibody production in an autoimmune MRL/lpr mouse. J Immunol 1994; 153: 5104-20.
51. VLAHAKOS D, FOSTER MH, UCCI A, BARRET J, DATTA SK, MADAIO MP: Murine monoclonal anti-DNA antibodies penetrate cells, bind to nuclei, and induce glomerular proliferation and proteinuria in vivo. J Am Soc Nephrol 1992; 2: 1345-54.
52. ALARCON-SEGOVIA, RUIZ-ARGUELLES A, LLORENTE L: Broken dogma: penetration of autoantibodies into living cells. Immunology Today 1996; 17: 163-4.
53. RAZ E, BEN-BASSAT H, DAVIDI T, SHLOMAI Z, EILAT D: Cross-reaction of anti-DNA autoantibodies with cell surface proteins. Eur J Immunol 1993; 23: 383-90.
54. HOLERS VM, KOTZIN BL: Human peripheral blood monocytes displays surface antigens recognized by monoclonal antinuclear antibodies. J Clin Invest 1985; 76: 991-8.
55. PRABHAKAR BS, ALLAWAY GP, SRINIVASAPPA J, NOTKINS AL: Cell surface expression of the 70-kD component of Ku, a DNA-binding nuclear autoantigen. J Clin Invest 1990; 86: 1301-5.
56. KOREN E, REICHLIN MW, KOSCEC M, FUGATE RD, REICHLIN M: Autoantibodies to the ribosomal P proteins react with a plasma membrane-related target on human cells. J Clin Invest 1993; 89: 1236-41.
57. LEFEBER WP, NORRIS DA, RYAN SR, JC HUFF, LEE LA, KUBO M, BOYCE ST, KOTZIN BL, WESTON WL: Ultraviolet light induces expression of selected nuclear antigens on cultured human keratinocytes. J Clin Invest 1984; 74: 1545-51.
58. GOLAN TD, ELKON KB, GHARAVI AE, KRUEGER JG: Enhanced membrane binding of autoantibodies to cultured keratinocytes of systemic lupus erythematosus patients after ultraviolet B/ultraviolet A irradiation. J Clin Invest 1992; 90: 1067-76.
59. CASCIOLA-ROSEN L, ANHALT G, ROSEN A: Autoantigen targeted in systemic lupus erythrmatosus are clustered in two populations of surface structures on apoptotic keratinocytes. J Exp Med 1994; 179: 1317-30.
60. KOREN E, KOSCEC M, WOLFSON-REICHLIN M, EBLING FM, TSAO B, HAHN BH, REICHLIN M: Murine and human antibodies to native DNA that cross-react with the A and D SnRNP polypeptides cause direct injury of cultured kidney cells. J Immunol 1995; 154: 4857-64.
61. ROSEN A, CASCIOLA-ROSEN L, AHEARN J: Novel packages of viral and self-antigens are generated during apop tosis. J Exp Med 1995; 181: 1557-61.
62. SUN KH, LIU WT, TSAI CY, TANG SJ, HAN SH, YU CL: Anti dsDNA antibodies cross-react with ribosomal P proteins expressed on the surface of glomerular mesangial cells to exert a cytostatic effect. Immunology 1995; 85: 262-9.
63. PANKEWYCZ OG, MIGLIORINI P, MADAIO MP: Polyreactive autoantibodies are nephritogenic in murine lupus nephritis. J Immunol 1987; 139: 3287-94.